Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia

Current Neurovascular Research

Volumn 8, Issue 2, 2011, Pages 145-152

  Ma, Lei ^a   Zhu, Zhenghua ^a   Zhao, Yu ^a   Hou, Lihong ^a   Wang, Qiang ^a   Xiong, Lize ^a   Zhu, Xiaoling ^a   Jia, Ji ^a   Chen, Shaoyang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

CB2 receptor; Cerebral ischemia; Electroacupuncture; Pretreatment.

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; COGNITION; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ACTIVITY; ELECTROACUPUNCTURE; HEMISPHERE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCORING SYSTEM; UPREGULATION;

EID: 79955745600     PISSN: 15672026     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720211795495394     Document Type: Article

References (34)

1. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986; 74(5): 1124-36. (Pubitemid 17174962)
2. Kitagawa K, Matsumoto M, Tagaya M, et al. "Ischemic tolerance" phenomenon found in the brain. Brain Res 1990; 528(1): 21-4. (Pubitemid 20292932)
3. Xiong LZ. Neuroanesthesia and neuroprotection: where are we now? Chin Med J (Engl) 2006; 119(11): 883-6.
4. Keep RF, Wang MM, Xiang J, Hua Y, Xi G. Is there a place for cerebral preconditioning in the clinic? Transl Stroke Res 2010; 1(1): 4-18.
5. Xiong L, Lu Z, Hou L, et al. Pretreatment with repeated electroacupuncture attenuates transient focal cerebral ischemic injury in rats. Chin Med J (Engl.) 2003; 116(1): 108-11. (Pubitemid 36432734)
6. Wang Q, Xiong L, Chen S, Liu Y, Zhu X. Rapid tolerance to focal cerebral ischemia in rats is induced by preconditioning with electroacupuncture: window of protection and the role of adenosine. Neurosci Lett 2005; 381(1-2): 158-62. (Pubitemid 40693161)
7. Wang Q, Peng Y, Chen S, et al. Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system. Stroke 2009; 40(6): 2157-64.
8. Wang Q, Li XY, Chen YK, et al. Activation of Epsilon Protein Kinase C-Mediated Anti-Apoptosis is Involved in Rapid Tolerance Induced by Electroacupuncture Pretreatment Through Cannabinoid Receptor Type 1. Stroke 2011; 42: 389-96.
9. Gong JP, Onaivi ES, Ishiguro H, et al. Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Res 2006; 1071(1): 10-23. (Pubitemid 43255471)
10. Onaivi ES, Ishiguro H, Gong JP, et al. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Ann N Y Acad Sci 2006; 1074: 514-36. (Pubitemid 44532857)
11. Fernández-Ruiz J, Pazos MR, García-Arencibia M, Sagredo O, Ramos JA. Role of CB2 receptors in neuroprotective effects of cannabinoids. Mol Cell Endocrinol 2008; 286(1-2 Suppl 1): S91-6.
12. Fern ández-Ruiz J, Romero J, Velasco G, Tol ón RM, Ramos JA, Guzmán M. Cannabinoid CB2 receptor: a new target for controlling neural cell survival? Trends Pharmacol Sci 2007; 28(1): 39-45. (Pubitemid 46038536)
13. Hillard CJ. Role of cannabinoids and endocannabinoids in cerebral ischemia. Curr Pharm Des 2008; 14(23): 2347-61.
14. Patel KD, Davison JS, Pittman QJ, Sharkey KA. Cannabinoid CB(2) receptors in health and disease. Curr Med Chem 2010; 17(14): 1393-410.
15. Pacher P, Hask ó G. Endocannabinoids and cannabinoid receptors in ischaemia-reperfusion injury and preconditioning. Br J Pharmacol 2008; 153(2): 252-62.
16. Zhang M, Martin BR, Adler MW, et al. Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke. J Neuroimmune Pharmacol 2009;4(2): 249-59.
17. Kang JM, Park HJ, Choi YG, et al. Acupuncture inhibits microglial activation and inflammatory events in the MPTP-induced mouse model. Brain Res 2007; 1131(1): 211-9. (Pubitemid 46053895)
18. Garcia JH, Wagner S, Liu KF, Hu XJ. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Stroke 1995; 26(4): 627-34.
19. Pagliaro P, Gattullo D, Rastaldo R, Losano G. Ischemic preconditioning from the first to the second window of protection. Life Sci 2001; 69(1): 1-15. (Pubitemid 32536730)
20. Xiong LZ, Yang J, Wang Q, Lu ZH. Involvement of delta-and muopioid receptors in the delayed cerebral ischemic tolerance induced by repeated electroacupuncture preconditioning in rats. Chin Med J (Engl) 2007; 120(5): 394-9. (Pubitemid 46488351)
21. Ashton JC, Rahman RM, Nair SM, Sutherland BA, Glass M, Appleton I. Cerebral hypoxia-ischemia and middle cerebral artery occlusion induce expression of the cannabinoid CB2 receptor in the brain. Neurosci Lett 2007; 412(2): 114-7.
22. Zhang M, Martin BR, Adler MW, Razdan RK, Jallo JI, Tuma RF. Cannabinoid CB(2) receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model. J Cereb Blood Flow Metab 2007; 27(7): 1387-96. (Pubitemid 46985356)
23. Zhang M, Martin BR, Adler MW, Razdan RK, Ganea D, Tuma RF. Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury. Neuroscience 2008; 152(3): 753-60.
24. Castillo A, Tolón MR, Fernández-Ruiz J, Romero J, Martinez- Orgado J. The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors. Neurobiol Dis 2010;37(2): 434-40.
25. Fern ández-L ópez D, Pazos MR, Tol ón RM, et al. The cannabinoid agonist WIN55212 reduces brain damage in an in vivo model of hypoxic-ischemic encephalopathy in newborn rats. Pediatr Res 2007; 62(3): 255-60.
26. Gao H, Guo J, Zhao P, Cheng J. The neuroprotective effects of electroacupuncture on focal cerebral ischemia in monkey. Acupunc Electrothe Res 2002; 27(1): 45-57. (Pubitemid 34546016)
27. Siu FK, Lo SC, Leung MC. Electroacupuncture reduces the extent of lipid peroxidation by increasing superoxide dismutase and glutathione peroxidase activities in ischemic-reperfused rat brains. Neurosc Lett 2004; 354(2): 158-62. (Pubitemid 38032857)
28. Yang L, Yang J, Wang Q, et al. Cardioprotective effects of electroacupuncture pretreatment on patients undergoing heart valve replacement surgery: a randomized controlled trial. Ann Thorac Surg 2010; 89(3): 781-6.
29. Lu ZH, Bai XG, Xiong LZ, Wang YH, Wang Y, Wang Q. Effect of electroacupuncture preconditioning on serum S100beta and NSE in patients undergoing craniocerebral tumor resection. Chin J Integr Med 2010; 16(3): 229-33.
30. Du J, Wang Q, Hu B, et al. Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats. Brain Res 2010; 1360: 1-7.
31. Ashton JC, Glass M. The cannabinoid CB2 receptor as a target for inflammation-dependent neurodegeneration. Curr Neuropharmacol 2007; 5(2): 73-80. (Pubitemid 47019422)
32. Murikinati S, Jüttler E, Keinert T, et al. Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment. FASEB J 2010; 24(3): 788-98.
33. Zhang M, Adler MW, Abood ME, Ganea D, Jallo J, Tuma RF. CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury. Microvasc Res 2009; 78(1): 86-94.
34. Torres E, Gutierrez-Lopez MD, Borcel E, et al. Evidence that MDMA ('ecstasy') increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain. J Neurochem 2010; 113(1): 67-78.