Prefrontal hypoactivity associated with impaired inhibition in stimulant-dependent individuals but evidence for hyperactivation in their unaffected siblings

Neuropsychopharmacology

Volumn 38, Issue 10, 2013, Pages 1945-1953

  Morein Zamir, Sharon ^a,b   Simon Jones, P ^a,b   Bullmore, Edward T ^a,b,c,d   Robbins, Trevor W ^a,b   Ersche, Karen D ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c CAMBRIDGESHIRE AND PETERBOROUGH NHS FOUNDATION TRUST   (United Kingdom)

^d ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

cognitive control; drug use; endophenotypes; fMRI; stimulant dependence; stop signal

Indexed keywords

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BEHAVIOR; BRAIN FUNCTION; BRAIN REGION; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; COPING BEHAVIOR; DRUG DEPENDENCE; ELECTROENCEPHALOGRAM; ENDOPHENOTYPE; EXECUTIVE FUNCTION; FEMALE; FIRST DEGREE RELATIVE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MALE; PREFRONTAL CORTEX; PRIORITY JOURNAL; REACTION TIME; SIBLING; STIMULANT DEPENDENT INDIVIDUAL; TASK PERFORMANCE;

ADULT; AMPHETAMINE-RELATED DISORDERS; BRAIN MAPPING; CASE-CONTROL STUDIES; COCAINE-RELATED DISORDERS; ENDOPHENOTYPES; FEMALE; GYRUS CINGULI; HUMANS; INHIBITION (PSYCHOLOGY); MALE; PREFRONTAL CORTEX; PSYCHOMOTOR PERFORMANCE; SIBLINGS;

EID: 84882455767     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.90     Document Type: Article

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