Cognitive Remediation in the Treatment of Stimulant Abuse Disorders: A Research Agenda

Experimental and Clinical Psychopharmacology

Volumn 16, Issue 6, 2008, Pages 484-497

  Vocci, Frank J ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

cognitive remediation; impulsivity; risky decision making

Indexed keywords

AMPHETAMINE; ATOMOXETINE; COCAINE; DESIPRAMINE; METHYLPHENIDATE; MODAFINIL; PLACEBO; VOLINANSERIN;

ATTENTION DEFICIT DISORDER; COGNITIVE DEFECT; COGNITIVE REHABILITATION; COMPUTER ASSISTED THERAPY; DECISION MAKING; HUMAN; IMPULSIVENESS; IOWA GAMBLING TASK; LEARNING; MONOAMINERGIC SYSTEM; NEUROPSYCHOLOGICAL TEST; NONHUMAN; PERSEVERATION; RESPONSE TIME; REVIEW; REWARD; RISKY DECISION MAKING; SUBSTANCE ABUSE; WISCONSIN CARD SORTING TEST; WORKING MEMORY;

CENTRAL NERVOUS SYSTEM STIMULANTS; COGNITION DISORDERS; COGNITIVE THERAPY; HUMANS; IMPULSIVE BEHAVIOR; PATIENT DROPOUTS; SUBSTANCE-RELATED DISORDERS; THERAPY, COMPUTER-ASSISTED; TREATMENT OUTCOME;

EID: 57949114704     PISSN: 10641297     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0014101     Document Type: Review

References (118)

1. Adinoff B., Devous M.D., Cooper D.B., Best S.E., Chandler P., Harris T., et al. Resting regional cerebral blood flow and gambling task performance in cocaine-dependent subjects and healthy comparison subjects. American Journal of Psychiatry 160 (2003) 1892-1894
2. Aharonovich E., Hasin D., Brooks A.C., Liu X., Bisaga A., and Nunes E.V. Cognitive deficits predict low treatment retention in cocaine dependent patients. Drug and Alcohol Dependence 81 (2006) 313-322
3. Ahmed S.H., and Koob G.F. Transition from moderate to excessive drug intake: Change in hedonic set point. Science 282 (1998) 298-300
4. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (1994), Author, Washington, DC
5. Anderson I.M., Clark L., Elliot R., Kulkarni B., Williams S.R., and Deakin J.F. 5-HT (2C) receptor activation by m-chlorophenylpiperazine detected in humans with fMRI. NeuroReport 13 (2002) 1547-1551
6. Ardila A., Roselli M., and Strumwasser S. Neuropsychological deficits in chronic cocaine abusers. International Journal of Neuroscience, 57 1 (1991) 73-79
7. Aron A.R., Dowson J.H., Sahakian B.J., and Robbins T.W. Methylphenidate improves response inhibition in adults with attention deficit/hyperactivity disorder. Biological Psychiatry 54 (2003) 465-1468
8. Aron A.R., Fletcher P.C., Bullmore E.T., Sahakian B.J., and Robbins T.W. Stop-signal inhibition disrupted by damage to the right inferior frontal gyrus. Nat Neurosci 6 (2003) 115-116
9. Baker D.A., McFarland K., Lake R.W., Shen H., Tang X.C., Toda S., et al. Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nature Neuroscience 6 (2003) 743-749
10. Barry D., and Petry N.M. Predictors of decision-making on the Iowa Gambling Task: Independent efforts of lifetime history of substance use disorders and performance on the Trail Making Test. Brain Cognition 66 (2008) 243-252
11. Beatty W.W., Katzung V.M., Moreland V.J., and Nixon S.J. Neuropsychological performance of recently abstinent alcoholics and cocaine abusers. Drug and Alcohol Dependence 37 (1995) 247-253
12. Bechara A., Damasio A.R., Damasio H., and Anderson S.W. Insensitivity to future consequences following damage to the human prefrontal cortex. Cognition 50 (1994) 7-15
13. Bechara A., Dolan S., Denberg N., Hindes A., Anderson S.W., and Nathan P.E. Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers. Neuropsychologia 39 (2001) 76-389
14. Bedard A.C., Ickowitz A., Logan G.D., Hogg-Johnson S., Schackar R., and Tannock R. Selective inhibition in children with attention-deficit disorder off and on stimulant medications. Journal of Abnormal Child Psychology 31 (2003) 315-327
15. Belin D., Mar A.C., Dalley J.W., Robbins T.W., and Everitt B.J. High impulsivity predicts the switch to compulsive cocaine-taking. Science 320 5881 (2008) 1352-1355
16. Berg E.A. A simple objective technique for measuring flexibility in thinking. Journal of General Psychology 39 (1948) 15-22
17. Bolla K.I., Eldreth D.A., London E.D., Kiehl K.A., Mouratidis M., Contoreggi, et al. Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task. Neuroimage 19 (2003) 1085-1094
18. Boulougouris V., Dalley J.W., and Robbins T.W. Effects of orbitofrontal, infralimbic, and prelimbic cortical lesions on serial spatial reversal learning in the rat. Behavioural Brain Research 179 (2007) 219-228
19. Bracy O. Visuospatial II. [Computer software] (1989), Psychological Software Services, Indianapolis, IN
20. Bracy O. Soft tools '90. [Computer software] (1990), Psychological Software Services, Indianapolis, IN
21. Calu D.J., Stalnaker T.A., Franz T.M., Singh T., Shaham Y., and Schoenbaum G. Withdrawal from cocaine self-administration produces long-lasting deficits in orbitofrontal-dependent reversal learning in rats. Learning and Memory 14 (2007) 325-328
22. 2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive perseveration in rats. Neuropsychopharmacology 31 (2006) 757-767
23. Carpenter K.M., Schreiber E., Church S., and McDowell D. Drug Stroop performance: Relationships with primary substance of abuse and treatment outcome in a drug-dependent outpatient sample. Addictive Behaviors 31 (2006) 174-181
24. Cervo L., Cocco A., Petrella C., and Heidbreder C.A. Selective antagonism at dopamine D3 receptors attenuates cocaine-seeking behaviour in the rat. International Journal of Neuropsychopharmacology 10 (2007) 167-181
25. Chamberlain S.R., Muller U., Blackwell A.D., Robbins T.W., and Sakahian B.J. Neurochemical modulation of response inhibition and probabilistic learning in humans. Science 311 (2006) 861-863
26. Clark L., Robbins T.W., Ersche K.D., and Sahakian B.J. Reflection impulsivity in current and former substance users. Biological Psychiatry 60 (2006) 515-522
27. Dalley J.W., Fryer T.D., Brichard L., Robinson E.S., Theobald D.E., Lääne K., et al. Nucleus accumbens D2/3 receptors predict trait impulsivity and cocaine reinforcement. Science 315 (2007) 1267-1270
28. Del-Ben C.M., Deakin J.F., McKie S., Delvai N.A., Williams S.R., Elliot R., et al. The effect of citalopram pretreatment on neuronal responses to neuropsychological tasks in normal volunteers: An FMRI study. Neuropsychopharmacology 30 (2005) 1724-1734
29. Devito E.E., Blackwell A.D., Kent L., Ersche K.D., Clark L., Salmond C.H., et al. The effects of methylphenidate on decision making in attention deficit/hyperactivity disorder. Biological Psychiatry 64 (2008) 636-639
30. Eagle D.M., Bari A., and Robbins T.W. The neuropharmacology of action inhibition: Cross-species translation of the stop-signal and go/no go tasks. Psychopharmacology 199 (2008) 439-456
31. Eagle D.M., Tufft M.R., Goodchild H.L., and Robbins T.W. Differential effects of modafinil and methylphenidate on stop-signal reaction time task performance in the rat, and interactions with the dopamine receptor antagonist cis-flupenthixol. Psychopharmacology (Berlin) 192 (2007) 193-206
32. Ersche K.D., Roiser J.J.P., Robbins T.W., and Sahakian B.J. Chronic cocaine but not chronic amphetamine use in associated with perseverative responding in humans. Psychopharmacology 197 (2008) 421-431
33. Evenden J.L. The pharmacology of impulsive behavior in rats VII: The effects of serotonergic agonists and antagonists on responding under a discriminative task using unreliable visual stimuli. Psychopharmacology 146 (1999) 422-431
34. Evenden J.L. Varieties of impulsivity. Psychopharmacology 146 (1999) 348-361
35. Fals-Stewart W. Neurocognitive defects and their impact on substance abuse treatment. Journal of Addict Offender Counseling 13 (1993) 46-57
36. Fals-Stewart W., and Lucente S. The effect of cognitive rehabilitation on the neuropsychological status of patients in drug abuse treatment who display neurocognitive impairment. Rehabilitation Psychology 39 (1994) 75-94
37. Fals-Stewart W., and Lucente S. Effects of neurocognitive status and personality functioning on length of stay in residential substance abuse treatment: An integrative study. Psychology of Addictive Behavior 8 (1994) 179-190
38. Fals-Stewart W., and Shafer J. The relationship between neurocognitive functioning and length of stay in a therapeutic community. Journal of Clinical Psychology 48 (1992) 539-543
39. Fellows L.K., and Farah M.J. Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans. Cerebral Cortex 15 (2005) 58-63
40. Field M., and Cox W.M. Attentional bias in addictive behaviors: A review of its development, causes, and consequences. Drug and Alcohol Dependence 97 (2008) 1-20
41. Fillmore M.T., and Rush C.R. Impaired inhibitory control in chronic cocaine users. Drug and Alcohol Dependence 66 (2002) 265-273
42. Fillmore M.T., Rush C.R., and Hays L. Acute effects of oral cocaine on inhibitory controls of behavior in humans. Drug and Alcohol Dependence 67 (2002) 157-167
43. Fillmore M.T., Rush C.R., and Marczinski C.A. Effects of d-amphetamine on behavioral control in stimulant abusers: The role of prepotent response tendencies. Drug and Alcohol Dependence 71 (2003) 143-152
44. Finger E.C., Marsh A.A., Mitchell D.G., Reid M.E., Sims C., Budhani S., et al. Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning. Archives of General Psychiatry 65 (2008) 586-594
45. Fletcher P.J., Tenn C.C., Rizos Z., Lovic V., and Kapur S. Sensitization to amphetamine, but not PCP, impairs attentional set shifting: Reversal by a D1 receptor agonist injected into the medial prefrontal cortex. Psychopharmacology (Berlin) 183 (2005) 190-200
46. Floresco S.B., Magyar O., Ghods-Sharifi S., Vexelman C., and Tse M.T. Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set shifting. Neuropsychopharmacology 31 (2006) 297-309
47. Gal K., and Gyertyan I. Dopamine D3 as well as D2 receptor ligands attenuate the cue-induced cocaine-seeking in a relapse model in rats. Drug and Alcohol Dependence 81 (2006) 63-70
48. Garavan H. Serial attention within working memory. Memory & Cognition 2692 (1998) 263-276
49. Garavan H., and Hester R. The role of cognitive control in cocaine dependence. Neuropsychology Review 17 (2007) 337-345
50. George D.T., Gilman J., Hersch J., Thorsell A., Herion D., Geyer C., et al. Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science 319 (2008) 1536-1539
51. Gilbert J.G., Newman A.H., Gardner E.L., Ashby Jr. C.R., Heidbreder C.A., Pak A.C., et al. Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: Role of dopamine D3 receptors. Synapse 57 (2005) 17-28
52. Goldman-Rakic P.S. Architecture of the prefrontal cortex and the central executive. Ann NY Acad Sci 769 (1995) 71-83
53. Goldstein R.Z., Tomasi D., Rajaram S., Cottone L.A., Zhang L., Telang F., et al. Role of the anterior cingulate and medial orbitalfrontal cortex in processing drug cues in cocaine addiction. Neuroscience 144 (2007) 1153-1159
54. Grohman K., and Fals-Stewart W. Computer-assisted cognitive rehabilitation with substance abusing patients: Effects on treatment response. Journal of Cognitive Rehabilitation 21 (2003) 1-9
55. Grohman K., Fals-Stewart W., and Donnelly K. Improving treatment response of cognitively impaired veterans with neuropsychological rehabilitation. Brain and Cognition 60 (2006) 203-204
56. Hatcher P.D., Brown V.J., Tait D.S., Bate S., Overend P., Hagan J.J., et al. 5-HT6 antagonists improve performance in an attentional set shifting task in rats. Psychopharmacology 181 (2005) 253-259
57. 6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders. Pharmacology Therapy 117 (2008) 207-231
58. Heinz A., Wrase J., Kahnt T., Beck A., Bromand Z., Grusser S.M., et al. Brain activation by affectively positive stimuli is associated with a lower risk of relapse in detoxified alcoholic subjects. Alcoholism, Clinical and Experimental Research 31 (2007) 1138-1147
59. Hester R., Dixon V., and Garavan H.A. Consistent attentional bias for drug-related material in active cocaine users across word and picture versions of the emotional Stroop task. Drug and Alcohol Dependence 81 (2006) 251-257
60. Jensen N.H., Rodriguiz R.M., Caron M.G., Wetsel W.C., Rothman R.B., and Roth B.L. N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT1A agonist, as a putative mediator of quetiapine's antidepressant activity. Neuropsychopharmacology 33 (2008) 2303-2312
61. Jentsch J.D., Olausson P., De La Garza II R., and Taylor J.R. Impairments of reversal learning and response perseveration after repeated, intermittent cocaine administrations to monkeys. Neuropsychopharmacology 26 (2002) 183-190
62. Kalivas, P., Moran, M., Melendez, R., LaRowe, S., Myrick, H., Malcolm, R., et al. (2005 December). Regulating glutamate homeostasis in treating cocaine addiction. Presented at the annual meeting of the American College of Neuropsychopharmacology, Waikoloa, HI.
63. Kubler A., Murphy K., and Garavan H. Cocaine dependence and attention switching within and between verbal and visouspatial working memory. European Journal of Neuroscience 21 (2005) 1984-1992
64. Lapiz M.D., Bondi C.O., and Morilak D.A. Chronic treatment with desipramine improves cognitive performance of rats in an attentional set-shifting test. Neuropsychopharmacology 32 (2007) 1000-1010
65. Lapiz M.D., and Morilak D.A. Noradrenergic modulation of cognitive function in rate medial prefrontal cortex as measured by attentional set-shifting test. Neuroscience 137 (2006) 1039-1049
66. LaRowe S.D., Myrick H., Mardikian P., Saladin M., McRae A., Brady K., et al. Is cocaine desire reduced by N-acetylcysteine?. American Journal of Psychiatry 164 (2007) 1115-1117
67. Ledgerwood L., Richardson R., and Cranney J. Effects of D-cycloserine on extinction of conditioned freezing. Behavioral Neuroscience 117 (2003) 341-349
68. Li C.S., Milivojevic V., Kemp K., Hong K., and Sinha R. Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence. Drug and Alcohol Dependence 85 (2006) 205-212
69. Liu Y.P., Wilkinson L.S., and Robbins T.W. Effects of acute and chronic buspirone on impulsive choice and efflux of 5-HT and dopamine in hippocampus, nucleus accumbens and prefrontal cortex. Psychopharmacology 173 (2004) 175-185
70. London E., Berman S.M., Voytek B., Simon S.L., Mandelkern M.A., Monterosso J., et al. Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers. Biological Psychiatry 58 (2005) 770-778
71. Mann R., Lee V., Porkess M.V., King M.V., Topham I.A., Marsden C.A., et al. Isolation rearing impairs recognition memory and reversal learning in rat. Journal of Psychopharmacology 19 (2005) A39
72. Moeller F.G., Barratt E.S., Dougherty D.M., Schmitz J.M., and Swann A.C. Psychiatric aspects of impulsivity. American Journal of Psychiatry 158 (2001) 1783-1793
73. Moeller F.G., Dougherty D.M., Barratt E.S., Schmitz J.M., Swann A.C., and Grabowski J. The impact of impulsivity on cocaine use and retention in treatment. Journal of Substance Abuse Treat 21 (2001) 193-198
74. Monterosso J.R., Aron A.R., Cordova X., Xu J., and London E.D. Deficits in response inhibition associated with chronic methamphetamine abuse. Drug and Alcohol Dependence 79 (2005) 273-277
75. Ornstein T.J., Iddon J.L., Baldacchino A.M., Sahakian B.J., London M., Everitt B.J., et al. Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers. Neuropsychopharmacology 23 (2000) 113-126
76. Overtoom C.C., Verbaten M.N., Kenner C., Kenemans J.L., van Engeland H., Buitelaar J.K., et al. Effects of methylphenidate, desipramine, and l-dopa on attention and inhibition in children with attention deficit disorder. Behavioural Brain Research 145 (2003) 7-15
77. Passetti F., Clark L., Mehta M.A., Joyce E., and King M. Neuropsychological predictors in clinical outcome in opiate addiction. Drug and Alcohol Dependence 94 (2008) 82-91
78. Pattij T., and Vanderschuren L.J. The neuropharmacology of impulsive behavior. Trends in Pharmacological Sciences 29 (2008) 192-199
79. Pezze M.A., Dalley J.W., and Robbins T.W. Differential roles of dopamine D1 and D2 receptors in the nucleus accumbens in attentional performance on the five-choice serial reaction time test. Neuropsychopharmacology 32 (2007) 273-283
80. Pilla M., Perachon S., Sautel F., Garrido F., Mann A., Wermuth C.G., et al. Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist. Nature 400 (1999) 371-375
81. Raskin J., Wiltse C.G., Siegal A., Sheikh J., Xu J., Dinkel J.J., et al. Efficacy of duloxetine on cognition, depression and pain in elderly patients with major depressive disorder: An 8 week, double-blind, placebo-controlled trial. American Journal of Psychiatry 164 (2007) 900-909
82. Ressler K.J., Rothbaum B.O., Tannenbaum L., Anderson P., Graap K., Zimand E., et al. Cognitive enhancers as adjuncts to psychotherapy: Use of D-cycloserine in phobic individuals to facilitate extinction of fear. Archives of General Psychiatry 61 (2004) 1136-1144
83. Richards J.B., Sabol K.E., and de Wit H. Effects of methamphetamine on the adjusting amount procedure, a model of impulsive behavior in rats. Psychopharmacology (Berlin) 146 (1999) 432-439
84. Robbins S.J., and Ehrman R.N. The role of attentional bias in substance abuse. Behavioral and Cognitive Neuroscience Review 3 (2004) 243-260
85. Robbins T.W. The 5-choice serial reaction time task: Behavioral pharmacology and functional neurochemistry. Psychopharmacology (Berlin) 163 (2002) 362-380
86. Robbins T.W., and Roberts A.C. Differential regulation of fronto-executive function by the monoamines and acetylcholine. Cerebral Cortex 17 Suppl. 1 (2007) i151-160
87. Robinson E.S., Dalley J.W., Theobald D.E.H., Glennon J.C., Pezze M.A., Murphy E.R., et al. Opposing roles for 5-HT 2A and 5-HT 2C receptors in the nucleus accumbens on inhibitory response control in the 5-choice serial reaction time test. Neuropsychopharmacology 33 (2008) 2398-2406
88. Robinson E.S., Eagle D.M., Mar A.C., Bari A., Banerjee G., Jiang X., et al. Similar effects of the selective noradrenaline reuptake inhibitor atomoxetine on three distinct forms of impulsivity in the rat. Neuropsychopharmacology 33 (2008) 1028-1037
89. Rogers R.D., Everitt B.J., Baldacchino A., Blackshaw A.J., Swainson R., Wynne K., et al. Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: Evidence for monoaminergic mechanisms. Neuropsychopharmacology 20 (1999) 322-339
90. Roselli M., Ardila A., Lubomski M., and Murray S. Personality profile and neuropsychological test performance in chronic cocaine abusers. International Journal of Neuroscience 110 (2001) 55-72
91. Salo R., Nordahl T.E., Moore C., Waters C., Natsuaki Y., Galloway G.P., et al. A dissociation in attentional control: Evidence from methamphetamine dependence. Biological Psychiatry 57 (2005) 310-313
92. Salo R., Nordahl T.E., Natsuaki Y., Leamon M.H., Galloway G.P., Waters C., et al. Attentional control and brain metabolite levels in methamphetamine abusers. Biological Psychiatry 61 (2007) 1272-1280
93. Salo R., Nordahl T.E., Posin K., Leamon M., Gibson D.R., Galloway G.P., et al. Preliminary evidence of reduced cognitive inhibition in methamphetamine-dependent individuals. Psychiatry Research 111 (2002) 65-74
94. Schoenbaum G., Nugent S.L., Saddoris M.P., and Setlow B. Orbitofrontal lesions impair reversal but not acquisition of a go, no go odor discrimination. NeuroReport 13 (2002) 885-890
95. Schrimsher G.W., Parker J.D., and Burke R.S. Relation between cognitive testing performance and pattern of substance use in males at treatment entry. The Clinical Neuropsychologist 21 (2007) 498-510
96. Seu, E., Lang, A., Rivera, R. J., & Jentsch, J. D. (in press). Inhibition of norepinephrine transporter improves behavioral flexibility in rats and monkeys. Psychopharmacology
97. Simon S.L., Domier C., Carnell J., Brethen P., Rawson R., and Ling W. Cognitive impairment in individuals currently using methamphetamine. American Journal on Addictions 9 (2000) 222-231
98. Simon S.L., Domier C.P., Sim T., Richardson K., Rawson R.A., and Ling W. Cognitive performance of current methamphetamine and cocaine abusers. Journal of Addictive Diseases 21 (2002) 61-67
99. Stalnaker T.A., Roesch M.R., Franz T.M., Burke K.A., and Schoenbaum G. Abnormal associative encoding in orbitofrontal neurons in cocaine-experienced rats during decision-making. European Journal of Neuroscience 24 (2006) 2643-2653
100. Streeter C.C., Terhune D.B., Whitfield T.H., Gruber S., Sarid-Segal O., Silveri M.M., et al. Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals. Neuropsychopharmacology 33 (2008) 827-836
101. Sukhotina I.A., Dravolina O.A., Novitskaya Y., Zvartau E.E., Danysz W., and Bespalov A.Y. Effects of m Glu1 receptor blockade on working memory, teime estimation, and impulsivity in rats. Psychopharmacology 196 (2008) 211-220
102. Thompson P.M., Hayashi K.M., Simon S.L., Geaga J.A., Hong M.S., Sui Y., et al. Structural abnormalities in the brains of human subjects who use methamphetamine. Journal of Neuroscience 24 (2004) 6028-6036
103. Turnbridge E.M., Bannerman D.M., Sharp T., and Harrison P.J. Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex. Journal of Neuroscience 24 (2004) 5331-5335
104. Turner D.C., Clark L., Dowson J., Robbins T.W., and Sahakian B.J. Modafinil improves cognition and response inhibition in adult attention deficit/hyperactivity disorder. Biological Psychiatry 55 (2004) 1031-1040
105. Turner D.C., Robbins T.W., Clark L., Aron A.R., Dowson J., and Sahakian B.J. Cognitive enhancing effects of modafinil in healthy volunteers. Psychopharmacology 165 (2003) 260-269
106. Van Gaalen M.M., Brueggeman R.J., Bronius P.F., Schoffelmeer A.N., and Vanderschuren L.J. Behavioral disinhibition requires dopamine receptor activation. Psychopharmacology 187 (2006) 73-85
107. Van Gaalen M.M., Van Koten R., Schoffelmeer A.N., and Vanderschuren L.J. Critical involvement of dopaminergic transmission in impulsive decision making. Biological Psychiatry 60 (2006) 66-73
108. Verdejo-Garcia A., Bechara A., Recknor E.C., and Perez-Garcia M. Decision-making and the Iowa Gambling Task: Ecological validity in individuals with substance dependence. Psychologica Belgica 46 (2006) 55-78
109. Verdejo-Garcia A., Perales J.C., and Perez-Garcia M. Cognitive impulsivity in cocaine and heroin polysubstance abusers. Addictive Behaviors 32 (2007) 950-966
110. Verdejo-Garcia A.V., and Perez-Garcia M. Profiles of executive deficits in cocaine and heroin polysubstance abusers: Common and differential effects on separate executive components. Psychopharmacology 190 (2007) 517-530
111. Vollm B., Richardson P., McKie S., Elliot R., Deakin J.F., and Anderson I.M. Serotonergic modulation of neuronal responses to behavioral inhibition and reinforcing stimuli: And fMRI study in normal volunteers. European Journal of Neuroscience 23 (2006) 552-560
112. Vorel S.R., Ashby Jr. C.R., Paul M., Liu X., Hayes R., Hagan J.J., et al. Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats. Journal of Neuroscience 22 (2002) 9595-9603
113. Wade T.R., de Wit H., and Richards J.B. Effects of dopaminergic drugs on delayed reward as a measure of impulsive behavior in rats. Psychopharmacology 150 (2000) 90-101
114. Walker D.L., Ressler K.J., Lu K.T., and Davis M. Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. Journal of Neuroscience 22 (2002) 2343-2351
115. Waters K.A., Burnham K.E., O'Connor D., Dawson G.R., and Dias R. Assessment of modafinil on attentional processes in a five-choice serial reaction time test in the rat. Journal of Psychopharmacology 19 (2005) 149-158
116. Wheeler R.A., Twining R.C., Jones J.L., Slater J.M., Grigson P.S., and Carelli R.M. Behavioral and electrophysiological indeces of negative affect predict cocaine self-administration. Neuron 57 (2008) 774-785
117. Wise R.A., and Bozarth M.A. A psychomotor stimulant theory of addiction. Psychological Review 94 (1987) 469-492
118. Zhou W., and Kalivas P.W. N-acetylcysteine reduces extinction responding and induces enduring reductions in cue-and heroin-induced drug-seeking. Biological Psychiatry 63 (2008) 338-340