-
1
-
-
77952896646
-
TGFbeta signalling: A complex web in cancer progression
-
Ikushima H, Miyazono K. TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer 2010; 10: 415-424.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 415-424
-
-
Ikushima, H.1
Miyazono, K.2
-
2
-
-
75749141315
-
Bone morphogenetic proteins and cancer: Review of the literature
-
Thawani JP, Wang AC, Than KD, Lin C-Y, La Marca F, Park P. Bone morphogenetic proteins and cancer: review of the literature. Neurosurgery 2010; 66: 233-246.
-
(2010)
Neurosurgery
, vol.66
, pp. 233-246
-
-
Thawani, J.P.1
Wang, A.C.2
Than, K.D.3
Lin, C.-Y.4
La Marca, F.5
Park, P.6
-
3
-
-
0034972978
-
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
-
Howe JR, Bair JL, Sayed MG, Anderson ME, Mitros FA, Petersen GM et al. Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis. Nat Genet 2001; 28: 184-187.
-
(2001)
Nat Genet
, vol.28
, pp. 184-187
-
-
Howe, J.R.1
Bair, J.L.2
Sayed, M.G.3
Anderson, M.E.4
Mitros, F.A.5
Petersen, G.M.6
-
4
-
-
42949160593
-
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers
-
Kodach LL, Wiercinska E, de Miranda NFCC, Bleuming SA, Musler AR, Peppelenbosch MP et al. The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers. Gastroenterology 2008; 134: 1332-13341.
-
(2008)
Gastroenterology
, vol.134
, pp. 1332-13341
-
-
Kodach, L.L.1
Wiercinska, E.2
De Miranda Nfcc3
Bleuming, S.A.4
Musler, A.R.5
Peppelenbosch, M.P.6
-
5
-
-
77954831976
-
Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development
-
Edson MA, Nalam RL, Clementi C, Franco HL, DeMayo FJ, Lyons KM et al. Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development. Mol Endocrinol 2010; 24: 1251-1266.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1251-1266
-
-
Edson, M.A.1
Nalam, R.L.2
Clementi, C.3
Franco, H.L.4
Demayo, F.J.5
Lyons, K.M.6
-
6
-
-
37549046846
-
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice
-
Pangas SA, Li X, Umans L, Zwijsen A, Huylebroeck D, Gutierrez C et al. Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol 2008; 28: 248-257.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 248-257
-
-
Pangas, S.A.1
Li, X.2
Umans, L.3
Zwijsen, A.4
Huylebroeck, D.5
Gutierrez, C.6
-
7
-
-
71949103390
-
Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors
-
Middlebrook BS, Eldin K, Li X, Shivasankaran S, Pangas SA. Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors. Endocrinology 2009; 150: 5208-5217.
-
(2009)
Endocrinology
, vol.150
, pp. 5208-5217
-
-
Middlebrook, B.S.1
Eldin, K.2
Li, X.3
Shivasankaran, S.4
Pangas, S.A.5
-
8
-
-
44149090296
-
Role of platelet-derived growth factors in physiology and medicine
-
Andrae J, Gallini R, Betsholtz C. Role of platelet-derived growth factors in physiology and medicine. Genes Dev 2008; 22: 1276-1312.
-
(2008)
Genes Dev
, vol.22
, pp. 1276-1312
-
-
Andrae, J.1
Gallini, R.2
Betsholtz, C.3
-
9
-
-
0032401819
-
Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus
-
Uhrbom L, Hesselager G, Nisté r M, Westermark B. Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus. Cancer Res 1998; 58: 5275-5279.
-
(1998)
Cancer Res
, vol.58
, pp. 5275-5279
-
-
Uhrbom, L.1
Hesselager, G.2
Nistér, M.3
Westermark, B.4
-
10
-
-
33846821916
-
High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene
-
Bruna A, Darken RS, Rojo F, Ocaña A, Peñ uelas S, Arias A et al. High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene. Cancer Cell 2007; 11: 147-160.
-
(2007)
Cancer Cell
, vol.11
, pp. 147-160
-
-
Bruna, A.1
Darken, R.S.2
Rojo, F.3
Ocaña, A.4
Peñuelas, S.5
Arias, A.6
-
11
-
-
37249010753
-
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
-
Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, Hoyng SA et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol 2008; 4: 33-41.
-
(2008)
Nat Chem Biol
, vol.4
, pp. 33-41
-
-
Yu, P.B.1
Hong, C.C.2
Sachidanandan, C.3
Babitt, J.L.4
Deng, D.Y.5
Hoyng, S.A.6
-
12
-
-
0037085441
-
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
-
Korchynskyi O, Ten DP. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem 2002; 277: 4883-4891.
-
(2002)
J Biol Chem
, vol.277
, pp. 4883-4891
-
-
Korchynskyi, O.1
Ten, D.P.2
-
13
-
-
0036479133
-
Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic proteinspecific transcriptional activation of Id1 gene
-
Ló pez-Rovira T, Chalaux E, Massagué J, Rosa JL, Ventura F. Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic proteinspecific transcriptional activation of Id1 gene. J Biol Chem 2002; 277: 3176-3185.
-
(2002)
J Biol Chem
, vol.277
, pp. 3176-3185
-
-
López-Rovira, T.1
Chalaux, E.2
Massagué, J.3
Rosa, J.L.4
Ventura, F.5
-
14
-
-
43049134130
-
Plateletderived growth factors (PDGF-A and -B) and their receptors in human fetal and adult ovaries
-
Pinkas H, Fisch B, Rozansky G, Felz C, Kessler-Icekson G, Krissi H et al. Plateletderived growth factors (PDGF-A and -B) and their receptors in human fetal and adult ovaries. Mol Hum Reprod 2008; 14: 199-206.
-
(2008)
Mol Hum Reprod
, vol.14
, pp. 199-206
-
-
Pinkas, H.1
Fisch, B.2
Rozansky, G.3
Felz, C.4
Kessler-Icekson, G.5
Krissi, H.6
-
15
-
-
12944270510
-
Characterization of an immortalized human granulosa cell line (COV434)
-
Zhang H, Vollmer M, De Geyter M, Litzistorf Y, Ladewig A, Dü rrenberger M et al. Characterization of an immortalized human granulosa cell line (COV434). Mol Hum Reprod 2000; 6: 146-153.
-
(2000)
Mol Hum Reprod
, vol.6
, pp. 146-153
-
-
Zhang, H.1
Vollmer, M.2
De Geyter, M.3
Litzistorf, Y.4
Ladewig, A.5
Dürrenberger, M.6
-
16
-
-
80455178772
-
ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif
-
Morikawa M, Koinuma D, Tsutsumi S, Vasilaki E, Kanki Y, Heldin C-H et al. ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif. Nucleic Acids Res 2011; 39: 8712-8727.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 8712-8727
-
-
Morikawa, M.1
Koinuma, D.2
Tsutsumi, S.3
Vasilaki, E.4
Kanki, Y.5
Heldin, C.-H.6
-
17
-
-
74949142886
-
Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination
-
Fei T, Xia K, Li Z, Zhou B, Zhu S, Chen H et al. Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination. Genome Res 2010; 20: 36-44.
-
(2010)
Genome Res
, vol.20
, pp. 36-44
-
-
Fei, T.1
Xia, K.2
Li, Z.3
Zhou, B.4
Zhu, S.5
Chen, H.6
-
18
-
-
0041374084
-
Transcription of the platelet-derived growth factor A-chain gene cytokine
-
Kaetzel DM. Transcription of the platelet-derived growth factor A-chain gene. Cytokine. Growth Factor Rev 2003; 14: 427-46.
-
(2003)
Growth Factor Rev
, vol.14
, pp. 427-446
-
-
Kaetzel, D.M.1
-
19
-
-
77949915025
-
SMAD3 and EGR1 physically and functionally interact in promoter-specific fashion
-
Fortin J, Bernard DJ. SMAD3 and EGR1 physically and functionally interact in promoter-specific fashion. Cell Signal 2010; 22: 936-43.
-
(2010)
Cell Signal
, vol.22
, pp. 936-943
-
-
Fortin, J.1
Bernard, D.J.2
-
20
-
-
0026464717
-
Human platelet-derived growth factor a chain is transcriptionally repressed by the wilms tumor suppressor WT1
-
Gashler AL, Bonthron DT, Madden SL, Rauscher FJ, Collins T, Sukhatme VP. Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc Natl Acad Sci USA 1992; 89: 10984-10988.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10984-10988
-
-
Gashler, A.L.1
Bonthron, D.T.2
Madden, S.L.3
Rauscher, F.J.4
Collins, T.5
Sukhatme, V.P.6
-
21
-
-
0033546366
-
GC factor 2 represses platelet-derived growth factor a-chain gene transcription and is itself induced by arterial injury
-
Khachigian LM, Santiago FS, Rafty LA, Chan OL, Delbridge GJ, Bobik A et al. GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury. Circ Res 1999; 84: 1258-1267.
-
(1999)
Circ Res
, vol.84
, pp. 1258-1267
-
-
Khachigian, L.M.1
Santiago, F.S.2
Rafty, L.A.3
Chan, O.L.4
Delbridge, G.J.5
Bobik, A.6
-
22
-
-
0036469899
-
NF1/X represses PDGF a-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter
-
Rafty LA, Santiago FS, Khachigian LM. NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter. EMBO J 2002; 21: 334-343.
-
(2002)
EMBO J
, vol.21
, pp. 334-343
-
-
Rafty, L.A.1
Santiago, F.S.2
Khachigian, L.M.3
-
23
-
-
0028788227
-
Interplay of sp1 and egr-1 in the proximal platelet-derived growth factor a-chain promoter in cultured vascular endothelial cells
-
Khachigian LM, Williams AJ, Collins T. Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells. J Biol Chem 1995; 270: 27679-27686.
-
(1995)
J Biol Chem
, vol.270
, pp. 27679-27686
-
-
Khachigian, L.M.1
Williams, A.J.2
Collins, T.3
-
24
-
-
0028058888
-
Platelet-derived growth factor a-chain gene transcription is mediated by positive and negative regulatory regions in the promoter
-
Kaetzel DM, Maul RS, Liu B, Bonthron D, Fenstermaker RA, Coyne DW. Platelet-derived growth factor A-chain gene transcription is mediated by positive and negative regulatory regions in the promoter. Biochem J 1994; 301: 321-327.
-
(1994)
Biochem J
, vol.301
, pp. 321-327
-
-
Kaetzel, D.M.1
Maul, R.S.2
Liu, B.3
Bonthron, D.4
Fenstermaker, R.A.5
Coyne, D.W.6
-
25
-
-
45849149957
-
High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF
-
Hoffmann A-C, Mori R, Vallbohmer D, Brabender J, Klein E, Drebber U et al. High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF. Neoplasia 2008; 10: 674-679.
-
(2008)
Neoplasia
, vol.10
, pp. 674-679
-
-
Hoffmann, A.-C.1
Mori, R.2
Vallbohmer, D.3
Brabender, J.4
Klein, E.5
Drebber, U.6
-
26
-
-
38649094903
-
Expression of platelet-derived growth factors and their receptors in ovarian clear-cell carcinoma and its putative precursors
-
Yamamoto S, Tsuda H, Takano M, Kita T, Kudoh K, Furuya K et al. Expression of platelet-derived growth factors and their receptors in ovarian clear-cell carcinoma and its putative precursors. Mod Pathol 2008; 21: 115-124.
-
(2008)
Mod Pathol
, vol.21
, pp. 115-124
-
-
Yamamoto, S.1
Tsuda, H.2
Takano, M.3
Kita, T.4
Kudoh, K.5
Furuya, K.6
-
27
-
-
31644442040
-
Platelet-derived growth factor (PDGF) and glial tumorigenesis
-
Shih AH, Holland EC. Platelet-derived growth factor (PDGF) and glial tumorigenesis. Cancer Lett 2006; 232: 139-147.
-
(2006)
Cancer Lett
, vol.232
, pp. 139-147
-
-
Shih, A.H.1
Holland, E.C.2
-
28
-
-
0141645497
-
Targeting PDGF receptors in cancer-rationales and proof of concept clinical trials
-
George D. Targeting PDGF receptors in cancer-rationales and proof of concept clinical trials. Adv Exp Med Biol 2003; 532: 141-151.
-
(2003)
Adv Exp Med Biol
, vol.532
, pp. 141-151
-
-
George, D.1
-
29
-
-
0037445186
-
Granulosa cell tumor of the ovary
-
Schumer ST, Cannistra SA. Granulosa cell tumor of the ovary. J Clin Oncol 2003; 21: 1180-1189.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1180-1189
-
-
Schumer, S.T.1
Cannistra, S.A.2
-
30
-
-
52449083054
-
Expression of c-kit and platelet-derived growth factor receptors in ovarian granulosa cell tumors
-
Rocconi RP, Matthews KS, Kimball KJ, Conner MG, Baker AC, Barnes MN. Expression of c-kit and platelet-derived growth factor receptors in ovarian granulosa cell tumors. Reprod Sci 2008; 15: 673-677.
-
(2008)
Reprod Sci
, vol.15
, pp. 673-677
-
-
Rocconi, R.P.1
Matthews, K.S.2
Kimball, K.J.3
Conner, M.G.4
Baker, A.C.5
Barnes, M.N.6
-
31
-
-
37449013816
-
Expression, mutational analysis and in vitro response of imatinib mesylate and nilotinib target genes in ovarian granulosa cell tumors
-
Chu S, Alexiadis M, Fuller PJ. Expression, mutational analysis and in vitro response of imatinib mesylate and nilotinib target genes in ovarian granulosa cell tumors. Gynecol Oncol 2008; 108: 182-190.
-
(2008)
Gynecol Oncol
, vol.108
, pp. 182-190
-
-
Chu, S.1
Alexiadis, M.2
Fuller, P.J.3
-
32
-
-
70350506325
-
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy- induced death
-
Gonfloni S, Di Tella L, Caldarola S, Cannata SM, Klinger FG, Di Bartolomeo C et al. Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy- induced death. Nat Med 2009; 15: 1179-1185.
-
(2009)
Nat Med
, vol.15
, pp. 1179-1185
-
-
Gonfloni, S.1
Di Tella, L.2
Caldarola, S.3
Cannata, S.M.4
Klinger, F.G.5
Di Bartolomeo, C.6
-
33
-
-
3543047952
-
Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist gremlin
-
Pangas SA, Jorgez CJ, Matzuk MM. Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist gremlin. J Biol Chem 2004; 279: 32281-32286.
-
(2004)
J Biol Chem
, vol.279
, pp. 32281-32286
-
-
Pangas, S.A.1
Jorgez, C.J.2
Matzuk, M.M.3
-
34
-
-
0036105591
-
RVista for comparative sequence-based discovery of functional transcription factor binding sites
-
Loots GG, Ovcharenko I, Pachter L, Dubchak I, Rubin EM. rVista for comparative sequence-based discovery of functional transcription factor binding sites. Genome Res 2002; 12: 832-839.
-
(2002)
Genome Res
, vol.12
, pp. 832-839
-
-
Loots, G.G.1
Ovcharenko, I.2
Pachter, L.3
Dubchak, I.4
-
35
-
-
77950675984
-
TEX14 interacts with CEP55 to block cell abscission
-
Iwamori T, Iwamori N, Ma L, Edson MA, Greenbaum MP, Matzuk MM. TEX14 interacts with CEP55 to block cell abscission. Mol Cell Biol 2010; 30: 2280-22892.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 2280-22892
-
-
Iwamori, T.1
Iwamori, N.2
Ma, L.3
Edson, M.A.4
Greenbaum, M.P.5
Matzuk, M.M.6
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