Genetic variations in interleukin-8 and interleukin-10 are associated with pain, depressed mood, and fatigue in lung cancer patients

Journal of Pain and Symptom Management

Volumn 46, Issue 2, 2013, Pages 161-172

  Reyes Gibby, Cielito C ^a   Wang, Jian ^a   Spitz, Margaret ^b   Wu, Xifeng ^a   Yennurajalingam, Sriram ^a   Shete, Sanjay ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

cytokines; depression; fatigue; genes; Pain; symptoms

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR BETA; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 16; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; LYMPHOTOXIN; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCYTE CHEMOTACTIC PROTEIN; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CANCER FATIGUE; CANCER PAIN; CANCER PATIENT; CANCER RISK; DEPRESSION; EARLY CANCER; FEMALE; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; RISK ASSESSMENT; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84882452503     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2012.07.019     Document Type: Article

References (74)

1. A. Jemal, R. Siegel, J. Xu, and E. Ward Cancer statistics, 2010 CA Cancer J Clin 60 2010 277 300
2. American Cancer Society. Cancer facts & figures 2010. 2011. Available from http://www.cancer.org/Research/CancerFactsFigures/CancerFactsFigures/ cancer-facts-and-figures-2010. Accessed July 2011.
3. L. Sarna, M.E. Cooley, and J.K. Brown Symptom severity 1 to 4 months after thoracotomy for lung cancer Am J Crit Care 17 2008 455 467
4. E.A. Engels, X. Wu, and J. Gu Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer Cancer Res 67 2007 6520 6527
5. L.M. Coussens, and Z. Werb Inflammation and cancer Nature 420 2002 860 867
6. D.S. O'Callaghan, D. O'Donnell, F. O'Connell, and K.J. O'Byrne The role of inflammation in the pathogenesis of non-small cell lung cancer J Thorac Oncol 5 2010 2024 2036
7. R.M. Bremnes, K. Al-Shibli, and T. Donnem The role of tumor-infiltrating immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer J Thorac Oncol 6 2011 824 833
8. B. Seruga, H. Zhang, L.J. Bernstein, and I.F. Tannock Cytokines and their relationship to the symptoms and outcome of cancer Nat Rev Cancer 8 2008 887 899
9. C.C. Reyes-Gibby, X. Wu, and M. Spitz Molecular epidemiology, cancer-related symptoms, and cytokines pathway Lancet Oncol 9 2008 777 785
10. B.N. Lee, R. Dantzer, and K.E. Langley A cytokine-based neuroimmunologic mechanism of cancer-related symptoms Neuroimmunomodulation 11 2004 279 292
11. S. Lundstrom, and C.J. Furst Symptoms in advanced cancer: relationship to endogenous cortisol levels Palliat Med 17 2003 503 508
12. G. Mantovani, A. Maccio, and P. Lai Cytokine involvement in cancer anorexia/cachexia: role of megestrol acetate and medroxyprogesterone acetate on cytokine downregulation and improvement of clinical symptoms Crit Rev Oncog 9 1998 99 106
13. C.C. Reyes-Gibby, B. El Osta, and M.R. Spitz The influence of tumor necrosis factor-alpha-308 G/A and IL-6-174 G/C on pain and analgesia response in lung cancer patients receiving supportive care Cancer Epidemiol Biomarkers Prev 17 2008 3262 3267
14. C.C. Reyes-Gibby, S. Shete, and S. Yennurajalingam Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes J Pain Symptom Manage 38 2009 894 902
15. S.M. Rausch, B.D. Gonzalez, and M.M. Clark SNPs in PTGS2 and LTA predict pain and quality of life in long term lung cancer survivors Lung Cancer 77 2012 217 223
16. C.C. Reyes-Gibby, M. Spitz, and X. Wu Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A Cancer Epidemiol Biomarkers Prev 16 2007 2745 2751
17. S.M. Rausch, M.M. Clark, and C. Patten Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors Cancer 116 2010 4103 4113
18. A. Collado-Hidalgo, J.E. Bower, P.A. Ganz, M.R. Irwin, and S.W. Cole Cytokine gene polymorphisms and fatigue in breast cancer survivors: early findings Brain Behav Immun 22 2008 1197 1200
19. W. Lee, and Y. Liu Simultaneous multiple response regression and inverse covariance matrix estimation via penalized Gaussian maximum likelihood J Multivar Anal 111 2012 241 255
20. L. Breiman, and J.H. Friedman Predicting multivariate responses in multiple linear regression J Roy Stat Soc B Appl Stat 59 1997 3 54
21. Q. Wei, L. Cheng, and C.I. Amos Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study J Natl Cancer Inst 92 2000 1764 1772
22. J. Ware Jr., M. Kosinski, and S.D. Keller A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity Med Care 34 1996 220 233
23. S. Yue, and X. Minge A note on dichotomization of continuous response variable in the presence of contamination and model misspecification Stat Med 29 2010 2200 2214
24. R.C. MacCallum, S. Zhang, K.J. Preacher, and D. Rucker On the practice of dichotomization of quantitative variables Psychol Methods 7 2002 19 40
25. P. Royston, D.G. Altman, and W. Sauerbrei Dichotomizing continuous predictors in multiple regression: a bad idea Stat Med 25 2006 127 141
26. National Comprehensive Cancer Network. Practice guidelines in oncology. 2010. Available from http://www.nccn.org/professionals/physician-gls/PDF/pain. pdf. Accessed September 12, 2007.
27. C.C. Reyes-Gibby, P.K. Morrow, A. Buzdar, and S. Shete Chemotherapy-induced peripheral neuropathy as a predictor of neuropathic pain in breast cancer patients previously treated with paclitaxel J Pain 10 2009 1146 1150
28. H.P. Zhang Classification trees for multiple binary responses J Am Stat Assoc 93 1998 180 193
29. L. Breiman, J.H. Friedman, R.A. Olshen, and C.J. Stone Classification and regression trees 1984 Wadsworth Pacific Grove, CA
30. D.R. Cox Analysis of multivariate binary data J Roy Stat Soc C Appl Stat 21 1972 113 120
31. L.P. Zhao, and R.L. Prentice Correlated binary regression using a quadratic exponential model Biometrika 77 1990 642 648
32. B. Puthothu, M. Krueger, J. Heinze, J. Forster, and A. Heinzmann Impact of IL8 and IL8-receptor alpha polymorphisms on the genetics of bronchial asthma and severe RSV infections Clin Mol Allergy 4 2006 2
33. S.H. Ahn, Y.W. Cho, and M.W. Ahn mRNA expression of cytokines and chemokines in herniated lumbar intervertebral discs Spine 27 2002 911 917
34. J.G. Burke, R.W. Watson, and D. McCormack Intervertebral discs which cause low back pain secrete high levels of proinflammatory mediators J Bone Joint Surg Br 84 2002 196 201
35. D.C. Ang, M.N. Moore, J. Hilligoss, and R. Tabbey MCP-1 and IL-8 as pain biomarkers in fibromyalgia: a pilot study Pain Med 12 2011 1154 1161
36. B.H. Natelson, S.A. Weaver, C.L. Tseng, and J.E. Ottenweller Spinal fluid abnormalities in patients with chronic fatigue syndrome Clin Diagn Lab Immunol 12 2005 52 55
37. S.B. Oh, P.B. Tran, and S.E. Gillard Chemokines and glycoprotein120 produce pain hypersensitivity by directly exciting primary nociceptive neurons J Neurosci 21 2001 5027 5035
38. R.A. Ribeiro, M.L. Vale, and S.M. Thomazzi Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice Eur J Pharmacol 387 2000 111 118
39. J.E. Bower, P.A. Ganz, and M.L. Tao Inflammatory biomarkers and fatigue during radiation therapy for breast and prostate cancer Clin Cancer Res 15 2009 5534 5540
40. J.E. Bower, P.A. Ganz, and M.R. Irwin Inflammation and behavioral symptoms after breast cancer treatment: do fatigue, depression, and sleep disturbance share a common underlying mechanism? J Clin Oncol 29 2011 3517 3522
41. S. Franciosi, H.B. Choi, S.U. Kim, and J.G. McLarnon IL-8 enhancement of amyloid-beta (Abeta 1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia J Neuroimmunol 159 2005 66 74
42. K.W. Moore, M.R. de Waal, R.L. Coffman, and A. O'Garra Interleukin-10 and the interleukin-10 receptor Annu Rev Immunol 19 2001 683 765
43. A.S. Ho, Y. Liu, and T.A. Khan A receptor for interleukin 10 is related to interferon receptors Proc Natl Acad Sci U S A 90 1993 11267 11271
44. S.V. Kotenko, C.D. Krause, and L.S. Izotova Identification and functional characterization of a second chain of the interleukin-10 receptor complex EMBO J 16 1997 5894 5903
45. Q.M. Gong, X.F. Kong, and Z.T. Yang Association study of IFNAR2 and IL10RB genes with the susceptibility and interferon response in HBV infection J Viral Hepat 16 2009 674 680
46. J. Sivula, H. Turpeinen, L. Volin, and J. Partanen Association of IL-10 and IL-10Rbeta gene polymorphisms with graft-versus-host disease after haematopoietic stem cell transplantation from an HLA-identical sibling donor BMC Immunol 10 2009 24
47. K. Hikami, Y. Ehara, and M. Hasegawa Association of IL-10 receptor 2 (IL10RB) SNP with systemic sclerosis Biochem Biophys Res Commun 373 2008 403 407
48. 2 synthesis and CGRP release in rat trigeminal ganglia cells PLoS One 6 2011 e17360
49. C. Martucci, A.E. Trovato, and B. Costa The purinergic antagonist PPADS reduces pain related behaviours and interleukin-1 beta, interleukin-6, iNOS and nNOS overproduction in central and peripheral nervous system after peripheral neuropathy in mice Pain 137 2008 81 95
50. B.T. Baune, U. Dannlowski, and K. Domschke The interleukin 1 beta (IL1B) gene is associated with failure to achieve remission and impaired emotion processing in major depression Biol Psychiatry 67 2010 543 549
51. D.M. Von Ah, D.H. Kang, and J.S. Carpenter Predictors of cancer-related fatigue in women with breast cancer before, during, and after adjuvant therapy Cancer Nurs 31 2008 134 144
52. A. Basu, J.K. Krady, and S.W. Levison Interleukin-1: a master regulator of neuroinflammation J Neurosci Res 78 2004 151 156
53. N. Muller, M. Riedel, and M.J. Schwarz Psychotropic effects of COX-2 inhibitors - a possible new approach for the treatment of psychiatric disorders Pharmacopsychiatry 37 2004 266 269
54. N. Muller, M.J. Schwarz, and S. Dehning The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine Mol Psychiatry 11 2006 680 684
55. R. Ramachandran, K.B. Ploug, and A. Hay-Schmidt Nitric oxide synthase (NOS) in the trigeminal vascular system and other brain structures related to pain in rats Neurosci Lett 484 2010 192 196
56. Y. Chen, M.K. Boettger, and A. Reif Nitric oxide synthase modulates CFA-induced thermal hyperalgesia through cytokine regulation in mice Mol Pain 6 2010 13
57. S. Presciuttini, M. Curcio, and R. Chillemi Promoter polymorphisms of the NOS3 gene are associated with hypnotizability-dependent vascular response to nociceptive stimulation Neurosci Lett 467 2009 252 255
58. S. Dolan, L.C. Field, and A.M. Nolan The role of nitric oxide and prostaglandin signaling pathways in spinal nociceptive processing in chronic inflammation Pain 86 2000 311 320
59. R.L. Handy, P. Wallace, and P.K. Moore Inhibition of nitric oxide synthase by isothioureas: cardiovascular and antinociceptive effects Pharmacol Biochem Behav 55 1996 179 184
60. J. Joubert, and S.F. Malan Novel nitric oxide synthase inhibitors: a patent review Expert Opin Ther Pat 21 2011 537 560
61. A. Kumar, R. Garg, V. Gaur, and P. Kumar Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice Indian J Pharmacol 43 2011 324 329
62. A. Kumar, R. Garg, and P. Kumar Nitric oxide modulation mediates the protective effect of trazodone in a mouse model of chronic fatigue syndrome Pharmacol Rep 60 2008 664 672
63. O.F. Sendur, Y. Turan, E. Tastaban, C. Yenisey, and M. Serter Serum antioxidants and nitric oxide levels in fibromyalgia: a controlled study Rheumatol Int 29 2009 629 633
64. M. Maes, I. Mihaylova, M. Kubera, and E. Bosmans Not in the mind but in the cell: increased production of cyclo-oxygenase-2 and inducible NO synthase in chronic fatigue syndrome Neuro Endocrinol Lett 28 2007 463 469
65. J. Nijs, B. Van de Velde, and K. De Meirleir Pain in patients with chronic fatigue syndrome: does nitric oxide trigger central sensitisation? Med Hypotheses 64 2005 558 562
66. T. Oates, and D. Jensen The effects of training set size on decision tree complexity Proceedings of the Fourteenth International Conference on Machine Learning 1997 Morgan Kaufmann San Francisco, CA 254 262
67. J. Morgan, R. Daugherty, A. Hilchie, and B. Carey Sample size and modeling accuracy of decision tree based data mining tools Acad Inform Manag Sci J 6 2003 71 99
68. P.-N. Tan, M. Steinbach, and V. Kumar Introduction to data mining 2006 Addison Wesley Boston, MA
69. M.P. Jensen, and C.A. McFarland Increasing the reliability and validity of pain intensity measurement in chronic pain patients Pain 55 1993 195 203
70. M.P. Jensen, T.J. Schnitzer, and H. Wang Sensitivity of single-domain versus multiple-domain outcome measures to identify responders in chronic low-back pain: pooled analysis of 2 placebo-controlled trials of etoricoxib Clin J Pain 28 2012 1 7
71. Z. Butt, L.I. Wagner, and J.L. Beaumont Use of a single-item screening tool to detect clinically significant fatigue, pain, distress, and anorexia in ambulatory cancer practice J Pain Symptom Manage 35 2008 20 30
72. D.E. Locke, P.A. Decker, and J.A. Sloan Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients J Pain Symptom Manage 34 2007 628 638
73. N. Risch, and H. Zhang Extreme discordant sib pairs for mapping quantitative trait loci in humans Science 268 1995 1584 1589
74. G.R. Abecasis, W.O. Cookson, and L.R. Cardon The power to detect linkage disequilibrium with quantitative traits in selected samples Am J Hum Genet 68 2001 1463 1474