Heat shock response activation exacerbates inclusion body formation in a cellular model of huntington disease

Journal of Biological Chemistry

Volumn 288, Issue 33, 2013, Pages 23633-23638

  Bersuker, Kirill ^a   Hipp, Mark S ^a,c   Calamini, Barbara ^b   Morimoto, Richard I ^b   Kopito, Ron R ^a  

^a STANFORD UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR MODEL; HEAT SHOCK RESPONSE; HEAT-SHOCK; HUNTINGTON DISEASE; INCLUSION BODIES; MUTANT HUNTINGTIN; THERAPEUTIC STRATEGY;

BIOCHEMISTRY;

BIOLOGY;

HEAT SHOCK TRANSCRIPTION FACTOR 1; HUNTINGTIN;

ARTICLE; CELL INCLUSION; CELL TRANSFORMATION; CONTROLLED STUDY; DISEASE EXACERBATION; EXON; GENE ACTIVATION; GENE OVEREXPRESSION; GENETIC ANALYSIS; HEAT SHOCK RESPONSE; HUNTINGTON CHOREA; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

FLOW CYTOMETRY; HEAT SHOCK PROTEIN; HEAT SHOCK RESPONSE; HUNTINGTON DISEASE; MOLECULAR CHAPERONE; PROTEIN AGGREGATION;

DNA-BINDING PROTEINS; HEAT-SHOCK RESPONSE; HEK293 CELLS; HUMANS; HUNTINGTON DISEASE; INCLUSION BODIES; MODELS, BIOLOGICAL; MUTANT PROTEINS; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 84882386037     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C113.481945     Document Type: Article

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