Tracking protein aggregation and mislocalization in cells with flow cytometry

Nature Methods

Volumn 9, Issue 5, 2012, Pages 467-470

  Ramdzan, Yasmin M ^a   Polling, Saskia ^a   Chia, Cheryl P Z ^a   Ng, Ivan H W ^a,b   Ormsby, Angelique R ^a   Croft, Nathan P ^a   Purcell, Anthony W ^a   Bogoyevitch, Marie A ^a   Ng, Dominic C H ^a   Gleeson, Paul A ^a   Hatters, Danny M ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; MONOMER; OLIGOMER;

ARTICLE; BIOSENSOR; CELL INCLUSION; CELL MEMBRANE; CELL NUCLEUS; CELL STRESS; CYTOPLASM; FLOW CYTOMETRY; GOLGI COMPLEX; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION;

CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEUS; CYTOPLASM; FLOW CYTOMETRY; GOLGI APPARATUS; HUMANS; HUNTINGTON DISEASE; INCLUSION BODIES; NERVE TISSUE PROTEINS; PROTEIN TRANSPORT;

MAMMALIA;

EID: 84860387931     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth.1930     Document Type: Article

References (18)

1. Hatters, D.M. IUBMB Life 60, 724-728 (2008).
2. Silveira, J.R. et al. Nature 437, 257-261 (2005).
3. Bucciantini, M. et al. Nature 416, 507-511 (2002).
4. Arrasate, M., Mitra, S., Schweitzer, E.S., Segal, M.R. & Finkbeiner, S. Nature 431, 805-810 (2004).
5. Johnston, J.A., Ward, C.L. & Kopito, R.R. J. Cell Biol. 143, 1883-1898 (1998).
6. Kaganovich, D., Kopito, R. & Frydman, J. Nature 454, 1088-1095 (2008).
7. De Vos, W.H., Van Neste, L., Dieriks, B., Joss, G.H. & Van Oostveldt, P. Cytometry A 77A, 64-75 (2010).
8. MacDonald, M.E. et al. Cell 72, 971-983 (1993).
9. Hoffman, R.A. Curr. Protoc. Cytom. 1.23.21-21.23.17 (2009).
10. Deng, H.X. et al. Science 261, 1047-1051 (1993).
11. Ramdzan, Y.M. et al. Chem. Biol. 17, 371-379 (2010).
12. Ossato, G. et al. Biophys. J. 98, 3078-3085 (2010).
13. Lajoie, P. & Snapp, E.L. PLoS ONE 5, e15245 (2011).
14. McKenna, B.K., Evans, J.G., Cheung, M.C. & Ehrlich, D.J. Nat. Methods 8, 401-403 (2011).
15. Rizzo, M.A., Springer, G.H., Granada, B. & Piston, D.W. Nat. Biotechnol. 22, 445-449 (2004).
16. Olshina, M.A. et al. J. Biol. Chem. 285, 21807-21816 (2010).
17. Johannes, L., Tenza, D., Antony, C. & Goud, B. J. Biol. Chem. 272, 19554-19561 (1997).
18. Mallard, F. et al. J. Cell Biol. 143, 973-990 (1998).