메뉴 건너뛰기




Volumn 57, Issue 9, 2013, Pages 4554-4558

Evaluation of combinations of 4=-ethynyl-2-fluoro-2=-deoxyadenosine with clinically used antiretroviral drugs

Author keywords

[No Author keywords available]

Indexed keywords

4' ETHYNYL 2 FLUORO 2' DEOXYADENOSINE; ADENOSINE DEAMINASE; EFAVIRENZ; EMTRICITABINE; ETRAVIRINE; LAMIVUDINE; RILPIVIRINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TENOFOVIR; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG; ZIDOVUDINE;

EID: 84882363875     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00283-13     Document Type: Article
Times cited : (22)

References (32)
  • 2
    • 4644275334 scopus 로고    scopus 로고
    • FDA approves two combination pills, Epzicom and Truvada; Comment on commercial race to once-a-day nucleosides
    • James JS. 2004. FDA approves two combination pills, Epzicom and Truvada; comment on commercial race to once-a-day nucleosides. AIDS Treat News 403:6. http://www.aidsnews.org/2004/08/epzicom-truvada .html.
    • (2004) AIDS Treat News , vol.403 , pp. 6
    • James, J.S.1
  • 3
    • 34548303425 scopus 로고    scopus 로고
    • The first once-daily single-tablet regimen for the treatment of HIV-infected patients
    • Killingley B, Pozniak A. 2007. The first once-daily single-tablet regimen for the treatment of HIV-infected patients. Drugs Today 43:427-442.
    • (2007) Drugs Today , vol.43 , pp. 427-442
    • Killingley, B.1    Pozniak, A.2
  • 4
    • 33744753057 scopus 로고    scopus 로고
    • In vitro evaluation of the anti-HIV activity and metabolic interactions of tenofovir and emtricitabine
    • Borroto-Esoda K, Vela JE, Myrick F, Ray AS, Miller MD. 2006. In vitro evaluation of the anti-HIV activity and metabolic interactions of tenofovir and emtricitabine. Antivir. Ther. 11:377-384.
    • (2006) Antivir. Ther. , vol.11 , pp. 377-384
    • Borroto-Esoda, K.1    Vela, J.E.2    Myrick, F.3    Ray, A.S.4    Miller, M.D.5
  • 5
    • 67649553022 scopus 로고    scopus 로고
    • The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: A mechanism of action study
    • doi:10.1186/1742-4690-6-44
    • Feng JY, Ly JK, Myrick F, Goodman D, White KL, Svarovskaia ES, Borroto-Esoda K, Miller MD. 2009. The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study. Retrovirology 6:44. doi:10.1186/1742-4690-6-44.
    • (2009) Retrovirology , vol.6 , pp. 44
    • Feng, J.Y.1    Ly, J.K.2    Myrick, F.3    Goodman, D.4    White, K.L.5    Svarovskaia, E.S.6    Borroto-Esoda, K.7    Miller, M.D.8
  • 10
    • 70349088181 scopus 로고    scopus 로고
    • Potent activity of a nucleoside reverse transcriptase inhibitor, 4=-ethynyl-2-fluoro-2=-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinase 3 knockout mice
    • Hattori S, Ide K, Nakata H, Harada H, Suzu S, Ashida N, Kohgo S, Hayakawa H, Mitsuya H, Okada S. 2009. Potent activity of a nucleoside reverse transcriptase inhibitor, 4=-ethynyl-2-fluoro-2=-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinase 3 knockout mice. Antimicrob. Agents Chemother. 53:3887-3893.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 3887-3893
    • Hattori, S.1    Ide, K.2    Nakata, H.3    Harada, H.4    Suzu, S.5    Ashida, N.6    Kohgo, S.7    Hayakawa, H.8    Mitsuya, H.9    Okada, S.10
  • 11
  • 12
    • 0024993530 scopus 로고
    • A three-dimensional model to analyze drug-drug interactions
    • Prichard MN, Shipman C, Jr. 1990. A three-dimensional model to analyze drug-drug interactions. Antiviral Res. 14:181-205.
    • (1990) Antiviral Res. , vol.14 , pp. 181-205
    • Prichard, M.N.1    Shipman Jr., C.2
  • 13
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC, Talalay P. 1984. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 22:27-55.
    • (1984) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 15
    • 0026563976 scopus 로고
    • Biochemical pharmacology of-And-2=,3=-dideoxy-3=-thiacytidine as anti-hepatitis B virus agents
    • Chang CN, Skalski V, Zhou JH, Cheng YC. 1992. Biochemical pharmacology of-and-2=,3=-dideoxy-3=-thiacytidine as anti-hepatitis B virus agents. J. Biol. Chem. 267:22414-22420.
    • (1992) J. Biol. Chem. , vol.267 , pp. 22414-22420
    • Chang, C.N.1    Skalski, V.2    Zhou, J.H.3    Cheng, Y.C.4
  • 16
    • 34347230952 scopus 로고    scopus 로고
    • Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L-and D-nucleosides
    • Sabini E, Hazra S, Konrad M, Lavie A. 2007. Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L-and D-nucleosides. J. Med. Chem. 50:3004-3014.
    • (2007) J. Med. Chem. , vol.50 , pp. 3004-3014
    • Sabini, E.1    Hazra, S.2    Konrad, M.3    Lavie, A.4
  • 17
    • 79251583792 scopus 로고    scopus 로고
    • K70Q adds high-level tenofovir resistance to "q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism
    • doi:10.1371/journal.pone.0016242
    • Hachiya A, Kodama EN, Schuckmann MM, Kirby KA, Michailidis E, Sakagami Y, Oka S, Singh K, Sarafianos SG. 2011. K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism. PLoS One 6:e16242. doi:10.1371/journal.pone.0016242.
    • (2011) PLoS One , vol.6
    • Hachiya, A.1    Kodama, E.N.2    Schuckmann, M.M.3    Kirby, K.A.4    Michailidis, E.5    Sakagami, Y.6    Oka, S.7    Singh, K.8    Sarafianos, S.G.9
  • 23
    • 0028919933 scopus 로고
    • The inhibition of human immunodeficiency virus type 1 in vitro by a nonnucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds
    • Brennan TM, Taylor DL, Bridges CG, Leyda JP, Tyms AS. 1995. The inhibition of human immunodeficiency virus type 1 in vitro by a nonnucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds. Antiviral Res. 26:173-187.
    • (1995) Antiviral Res. , vol.26 , pp. 173-187
    • Brennan, T.M.1    Taylor, D.L.2    Bridges, C.G.3    Leyda, J.P.4    Tyms, A.S.5
  • 24
    • 0036090544 scopus 로고    scopus 로고
    • Potency of nonnucleoside reverse transcriptase inhibitors (NNRTIs) used in combination with other human immunodeficiency virus NNRTIs, NRTIs, or protease inhibitors
    • King RW, Klabe RM, Reid CD, Erickson-Viitanen SK. 2002. Potency of nonnucleoside reverse transcriptase inhibitors (NNRTIs) used in combination with other human immunodeficiency virus NNRTIs, NRTIs, or protease inhibitors. Antimicrob. Agents Chemother. 46: 1640-1646.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 1640-1646
    • King, R.W.1    Klabe, R.M.2    Reid, C.D.3    Erickson-Viitanen, S.K.4
  • 25
    • 0035080175 scopus 로고    scopus 로고
    • Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and D-and L-(beta)-dideoxynucleoside triphosphate analogs
    • Maga G, Hubscher U, Pregnolato M, Ubiali D, Gosselin G, Spadari S. 2001. Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and D-and L-(beta)-dideoxynucleoside triphosphate analogs. Antimicrob. Agents Chemother. 45:1192-1200.
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1192-1200
    • Maga, G.1    Hubscher, U.2    Pregnolato, M.3    Ubiali, D.4    Gosselin, G.5    Spadari, S.6
  • 26
    • 0032992656 scopus 로고    scopus 로고
    • The thiocarboxanilide nonnucleoside inhibitor UC781 restores antiviral activity of 3=-azido-3=-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus type 1
    • Borkow G, Arion D, Wainberg MA, Parniak MA. 1999. The thiocarboxanilide nonnucleoside inhibitor UC781 restores antiviral activity of 3=-azido-3=-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus type 1. Antimicrob. Agents Chemother. 43:259-263.
    • (1999) Antimicrob. Agents Chemother. , vol.43 , pp. 259-263
    • Borkow, G.1    Arion, D.2    Wainberg, M.A.3    Parniak, M.A.4
  • 27
    • 0142242148 scopus 로고    scopus 로고
    • Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3=-azido-3=-deoxythymidine (AZT)-resistant polymerase to AZT-5=-triphosphate
    • Odriozola L, Cruchaga C, Andreola M, Dolle V, Nguyen CH, Tarrago-Litvak L, Perez-Mediavilla A, Martinez-Irujo JJ. 2003. Non-nucleoside inhibitors of HIV-1 reverse transcriptase inhibit phosphorolysis and resensitize the 3=-azido-3=-deoxythymidine (AZT)-resistant polymerase to AZT-5=-triphosphate. J. Biol. Chem. 278:42710-42716.
    • (2003) J. Biol. Chem. , vol.278 , pp. 42710-42716
    • Odriozola, L.1    Cruchaga, C.2    Andreola, M.3    Dolle, V.4    Nguyen, C.H.5    Tarrago-Litvak, L.6    Perez-Mediavilla, A.7    Martinez-Irujo, J.J.8
  • 28
    • 14644441681 scopus 로고    scopus 로고
    • Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3=-azido-3=-deoxythymidine with nonnucleoside inhibitors
    • Cruchaga C, Odriozola L, Andreola M, Tarrago-Litvak L, Martinez-Irujo JJ. 2005. Inhibition of phosphorolysis catalyzed by HIV-1 reverse transcriptase is responsible for the synergy found in combinations of 3=-azido-3=-deoxythymidine with nonnucleoside inhibitors. Biochemistry 44:3535-3546.
    • (2005) Biochemistry , vol.44 , pp. 3535-3546
    • Cruchaga, C.1    Odriozola, L.2    Andreola, M.3    Tarrago-Litvak, L.4    Martinez-Irujo, J.J.5
  • 29
    • 1342325435 scopus 로고    scopus 로고
    • Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs
    • Basavapathruni A, Bailey CM, Anderson KS. 2004. Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs. J. Biol. Chem. 279:6221-6224.
    • (2004) J. Biol. Chem. , vol.279 , pp. 6221-6224
    • Basavapathruni, A.1    Bailey, C.M.2    Anderson, K.S.3
  • 30
    • 38549172567 scopus 로고    scopus 로고
    • Efavirenz accelerates HIV-1 reverse transcriptase ribonuclease H cleavage, leading to diminished zidovudine excision
    • Radzio J, Sluis-Cremer N. 2008. Efavirenz accelerates HIV-1 reverse transcriptase ribonuclease H cleavage, leading to diminished zidovudine excision. Mol. Pharmacol. 73:601-606.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 601-606
    • Radzio, J.1    Sluis-Cremer, N.2
  • 32
    • 14744267571 scopus 로고    scopus 로고
    • In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase
    • Parikh UM, Koontz DL, Chu CK, Schinazi RF, Mellors JW. 2005. In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase. Antimicrob. Agents Chemother. 49:1139-1144.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 1139-1144
    • Parikh, U.M.1    Koontz, D.L.2    Chu, C.K.3    Schinazi, R.F.4    Mellors, J.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.