메뉴 건너뛰기




Volumn 50, Issue , 2013, Pages 85-95

Coagulation monitoring devices: Past, present, and future at the point of care

Author keywords

Anticoagulant; Blood; Clinical diagnostics; Clotting time; Coagulation; Device; Hematology; Miniaturization; Monitoring; Point of care (POC)

Indexed keywords

BLOOD; DRUG PRODUCTS; MONITORING;

EID: 84882263834     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2013.05.009     Document Type: Review
Times cited : (56)

References (76)
  • 1
    • 18844444286 scopus 로고    scopus 로고
    • Combi. High throughput coagulation analyzers review
    • Qari M.H. Combi. High throughput coagulation analyzers review. Chem. High Throughput Screen. 2005, 8:353-360.
    • (2005) Chem. High Throughput Screen. , vol.8 , pp. 353-360
    • Qari, M.H.1
  • 3
    • 0000333461 scopus 로고
    • A study of the coagulation defect in hemophilia and in jaundice
    • Quick A.J., Stanleybrown M., Bancroft F.W. A study of the coagulation defect in hemophilia and in jaundice. Am. J. Med. Sci. 1935, 190:501-511.
    • (1935) Am. J. Med. Sci. , vol.190 , pp. 501-511
    • Quick, A.J.1    Stanleybrown, M.2    Bancroft, F.W.3
  • 6
    • 84860116862 scopus 로고    scopus 로고
    • Laboratory tests of hemostasis
    • Blackwell Publishing, Massachusetts, D. O'Shaughnessy, M. Makris, D. Lillicrap (Eds.)
    • Kitchen S., Makris M. Laboratory tests of hemostasis. Practical Hemostasis and Thrombosis 2005, 8-17. Blackwell Publishing, Massachusetts. D. O'Shaughnessy, M. Makris, D. Lillicrap (Eds.).
    • (2005) Practical Hemostasis and Thrombosis , pp. 8-17
    • Kitchen, S.1    Makris, M.2
  • 10
    • 23944440217 scopus 로고    scopus 로고
    • Chromogenic methods in coagulation diagnostics
    • Rosen S. Chromogenic methods in coagulation diagnostics. Hamostaseologie 2005, 25:259-266.
    • (2005) Hamostaseologie , vol.25 , pp. 259-266
    • Rosen, S.1
  • 13
    • 78649996833 scopus 로고    scopus 로고
    • Immunoassays for diagnosis of coagulation disorders
    • Kappel A., Ehm M. Immunoassays for diagnosis of coagulation disorders. Hamostaseologie 2010, 30:194-201.
    • (2010) Hamostaseologie , vol.30 , pp. 194-201
    • Kappel, A.1    Ehm, M.2
  • 14
    • 55049104838 scopus 로고    scopus 로고
    • Point of care coagulation tests in critically ill patients
    • Dempfle C.E., Borggrefe M. Point of care coagulation tests in critically ill patients. Semin. Thromb. Hemost. 2008, 34:445-450.
    • (2008) Semin. Thromb. Hemost. , vol.34 , pp. 445-450
    • Dempfle, C.E.1    Borggrefe, M.2
  • 15
    • 84903362136 scopus 로고    scopus 로고
    • Perioperative point of care coagulation testing
    • Weber C.F., Zacharowski K. Perioperative point of care coagulation testing. Dtsch. Arztebl. Int. 2012, 109:369-375.
    • (2012) Dtsch. Arztebl. Int. , vol.109 , pp. 369-375
    • Weber, C.F.1    Zacharowski, K.2
  • 16
    • 77956479323 scopus 로고    scopus 로고
    • Point of care testing in a large urban academic medical center: evolving test menu and clincal applications
    • Lee-Lewandrowski E., Gregory K., Lewandrowski K. Point of care testing in a large urban academic medical center: evolving test menu and clincal applications. Clin. Chim. Acta 2010, 411:1799-1805.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 1799-1805
    • Lee-Lewandrowski, E.1    Gregory, K.2    Lewandrowski, K.3
  • 17
    • 70249123145 scopus 로고    scopus 로고
    • A systematic review of emergency department point-of-care cardiac markers and efficiency measures
    • Storrow A.B., Lyon J.A., Porter M.W., Chuan Z., Jin Ho H., Lindsell C.J. A systematic review of emergency department point-of-care cardiac markers and efficiency measures. Point of Care 2009, 8:121-125.
    • (2009) Point of Care , vol.8 , pp. 121-125
    • Storrow, A.B.1    Lyon, J.A.2    Porter, M.W.3    Chuan, Z.4    Jin Ho, H.5    Lindsell, C.J.6
  • 19
    • 84861124675 scopus 로고    scopus 로고
    • Use of point-of-care testing for plasma therapy
    • Goodnough L.T., Hill C.C. Use of point-of-care testing for plasma therapy. Transfusion 2012, 52:56-64.
    • (2012) Transfusion , vol.52 , pp. 56-64
    • Goodnough, L.T.1    Hill, C.C.2
  • 21
    • 0028953273 scopus 로고
    • Changes in transfusion therapy and reexploration rate after institution of a blood management program in cardiac surgical patients
    • Spiess B.D., Gillies B.S., Chandler W., Verrier E. Changes in transfusion therapy and reexploration rate after institution of a blood management program in cardiac surgical patients. J. Cardiothorac. Vasc. Anesth. 1995, 9:168-173.
    • (1995) J. Cardiothorac. Vasc. Anesth. , vol.9 , pp. 168-173
    • Spiess, B.D.1    Gillies, B.S.2    Chandler, W.3    Verrier, E.4
  • 23
    • 84882271120 scopus 로고    scopus 로고
    • Solid state apparatus employing Hall effect sensors for detecting the coagulation of blood, Patent No. 6,136,271
    • R. Lorincz, R. Hall, Solid state apparatus employing Hall effect sensors for detecting the coagulation of blood, Patent No. 6,136,271 (2000).
    • (2000)
    • Lorincz, R.1    Hall, R.2
  • 24
    • 0347928631 scopus 로고    scopus 로고
    • Activated clotting time systems vary in precision and bias and are not interchangeable when following heparin management protocols during cardiopulmonary bypass
    • Welsby I.J., McDonnell E., El-Moalem H., Stafford-Smith M., Toffaletti J.G. Activated clotting time systems vary in precision and bias and are not interchangeable when following heparin management protocols during cardiopulmonary bypass. J. Clin. Monit. Comput. 2002, 17:287-292.
    • (2002) J. Clin. Monit. Comput. , vol.17 , pp. 287-292
    • Welsby, I.J.1    McDonnell, E.2    El-Moalem, H.3    Stafford-Smith, M.4    Toffaletti, J.G.5
  • 25
    • 0347812212 scopus 로고    scopus 로고
    • Point-of-care testing of hemostasis in cardiac surgery
    • Prisco D., Paniccia R. Point-of-care testing of hemostasis in cardiac surgery. Thromb. J. 2003, 6:1-10.
    • (2003) Thromb. J. , vol.6 , pp. 1-10
    • Prisco, D.1    Paniccia, R.2
  • 27
    • 84882269521 scopus 로고    scopus 로고
    • Top 200 prescription drugs of, (last accessed 22.04.13).
    • M. Bartholow, Top 200 prescription drugs of 2009, <>, (last accessed 22.04.13). http://www.pharmacytimes.com/publications/issue/2010/May2010/RxFocusTopD rugs-0510.
    • (2009)
    • Bartholow, M.1
  • 28
    • 52249108492 scopus 로고    scopus 로고
    • Heparin: from animal organ extract to designer drug
    • Middeldorp S. Heparin: from animal organ extract to designer drug. Thromb. Res. 2008, 122:753-762.
    • (2008) Thromb. Res. , vol.122 , pp. 753-762
    • Middeldorp, S.1
  • 29
    • 1342330479 scopus 로고    scopus 로고
    • Comparative study of two portable systems for oral anticoagulant monitoring
    • Vacas M., Lafuente P.J., Unanue I., Iriarte J.A. Comparative study of two portable systems for oral anticoagulant monitoring. Haematol. J. 2004, 5:35-38.
    • (2004) Haematol. J. , vol.5 , pp. 35-38
    • Vacas, M.1    Lafuente, P.J.2    Unanue, I.3    Iriarte, J.A.4
  • 30
    • 9044225510 scopus 로고
    • A comparison of activated partial thromboplastin time methods for control of heparin therapy
    • Kitchen S., Preston F.E. A comparison of activated partial thromboplastin time methods for control of heparin therapy. Thromb. Haemost. 1993, 69:1106-1107.
    • (1993) Thromb. Haemost. , vol.69 , pp. 1106-1107
    • Kitchen, S.1    Preston, F.E.2
  • 31
    • 84882241366 scopus 로고    scopus 로고
    • Review Memorandum, Substantial equivalence determination decision summary, (last accessed 22.04.13).
    • Review Memorandum, Substantial equivalence determination decision summary, <>, (last accessed 22.04.13). http://www.accessdata.fda.gov/cdrh_docs/reviews/K093243.pdf.
  • 32
    • 84882278800 scopus 로고    scopus 로고
    • CoaguSense Inc., CoaguSense self-testing PT monitoring system, Department of Health (last accessed 22.04.13).
    • CoaguSense Inc., CoaguSense self-testing PT monitoring system, Department of Health, 2010, <> (last accessed 22.04.13). http://www.coagusense.com/professionals.php.
    • (2010)
  • 33
    • 85025400642 scopus 로고
    • The electrophoresis of the blood platelets of the horse with reference to their origin and to thrombus formation
    • Abramson H.A. The electrophoresis of the blood platelets of the horse with reference to their origin and to thrombus formation. J. Exp. Med. 1928, 47:677-683.
    • (1928) J. Exp. Med. , vol.47 , pp. 677-683
    • Abramson, H.A.1
  • 34
    • 0344009686 scopus 로고    scopus 로고
    • Quantitative evaluation of thrombosis by electrochemical methodology
    • Shih C.C., Shih C.M., Su Y.Y., Su L.H.J., Chang M.S., Lin S.J. Quantitative evaluation of thrombosis by electrochemical methodology. Thromb. Res. 2003, 111:103-109.
    • (2003) Thromb. Res. , vol.111 , pp. 103-109
    • Shih, C.C.1    Shih, C.M.2    Su, Y.Y.3    Su, L.H.J.4    Chang, M.S.5    Lin, S.J.6
  • 36
    • 62149152387 scopus 로고    scopus 로고
    • Monitoring thrombin generation by electrochemistry: development of an amperometric biosensor screening test for plasma and whole blood
    • Thuerlemann C., Haeberli A., Alberio L. Monitoring thrombin generation by electrochemistry: development of an amperometric biosensor screening test for plasma and whole blood. Clin. Chem. 2009, 55:505-512.
    • (2009) Clin. Chem. , vol.55 , pp. 505-512
    • Thuerlemann, C.1    Haeberli, A.2    Alberio, L.3
  • 37
    • 79952111488 scopus 로고    scopus 로고
    • Comparison of International Normalized Ratios provided by two point-of-care devices and laboratory-based venipuncture in a pharmacist-managed anticoagulation clinic
    • Donaldson M., Sullivan J., Norbeck A. Comparison of International Normalized Ratios provided by two point-of-care devices and laboratory-based venipuncture in a pharmacist-managed anticoagulation clinic. Am. J. Health Syst. Pharm. 2010, 67:1616-1622.
    • (2010) Am. J. Health Syst. Pharm. , vol.67 , pp. 1616-1622
    • Donaldson, M.1    Sullivan, J.2    Norbeck, A.3
  • 38
    • 79751481988 scopus 로고    scopus 로고
    • Impact of i-stat point of care implementation in a pharmacist-managed anticoagulation clinic: a retrospective analysis
    • Challen L.M., Nguyen T.G., Villalon A. Impact of i-stat point of care implementation in a pharmacist-managed anticoagulation clinic: a retrospective analysis. Hosp. Pharm. 2011, 46:105-109.
    • (2011) Hosp. Pharm. , vol.46 , pp. 105-109
    • Challen, L.M.1    Nguyen, T.G.2    Villalon, A.3
  • 39
    • 84882272211 scopus 로고    scopus 로고
    • Electrochemical test strip with an integrated micro-needle and associated methods, Patent No. 7,144,495
    • M. Teodorczyk, E.J. Kiser, L.P. Olson, D. McAllister, V. V Yuzhakov, K.W. Leong, Electrochemical test strip with an integrated micro-needle and associated methods, Patent No. 7,144,495 (2006).
    • (2006)
    • Teodorczyk, M.1    Kiser, E.J.2    Olson, L.P.3    McAllister, D.4    Yuzhakov, V.V.5    Leong, K.W.6
  • 40
    • 84882288038 scopus 로고    scopus 로고
    • Coagulation or lysis assays by measuring impedance, Patent No. 6,673,622
    • J. Arvind, Coagulation or lysis assays by measuring impedance, Patent No. 6,673,622 (2004).
    • (2004)
    • Arvind, J.1
  • 41
    • 57549089843 scopus 로고    scopus 로고
    • Cellular procoagulant activity dictates clot structure and stability as a function of distance from the cell surface
    • Campbell R.A., Overmyer K.A., Bagnell C.R., Wolberg A.S. Cellular procoagulant activity dictates clot structure and stability as a function of distance from the cell surface. Arterioscler. Thromb. Vasc. Biol. 2009, 28:2247-2254.
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.28 , pp. 2247-2254
    • Campbell, R.A.1    Overmyer, K.A.2    Bagnell, C.R.3    Wolberg, A.S.4
  • 43
    • 84867361758 scopus 로고    scopus 로고
    • Accelerated in vivo thrombin formation independently predicts the presence and severity of CT angiographic coronary atherosclerosis
    • Borissoff J.I., Joosen I.A., Versteylen M.O., Spronk H.M., ten Cate H., Hofstra L. Accelerated in vivo thrombin formation independently predicts the presence and severity of CT angiographic coronary atherosclerosis. Cardiovasc. Imaging 2012, 5:1201-1210.
    • (2012) Cardiovasc. Imaging , vol.5 , pp. 1201-1210
    • Borissoff, J.I.1    Joosen, I.A.2    Versteylen, M.O.3    Spronk, H.M.4    ten Cate, H.5    Hofstra, L.6
  • 48
    • 12444330291 scopus 로고    scopus 로고
    • Biosensors in clincal chemistry
    • D'Orazio P. Biosensors in clincal chemistry. Clin. Chim. Acta 2003, 334:41-69.
    • (2003) Clin. Chim. Acta , vol.334 , pp. 41-69
    • D'Orazio, P.1
  • 49
    • 42449112966 scopus 로고    scopus 로고
    • Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices
    • Ganter M.T., Hofer C.K. Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices. Anesth. Analg. 2008, 106:1366-1375.
    • (2008) Anesth. Analg. , vol.106 , pp. 1366-1375
    • Ganter, M.T.1    Hofer, C.K.2
  • 50
    • 84882280282 scopus 로고    scopus 로고
    • Microvisk Ltd., Handheld blood coagulation device, Trustech NHS ,(last accessed 22.04.13).
    • A. Warner, Microvisk Ltd., Handheld blood coagulation device, Trustech NHS 2012, <>, (last accessed 22.04.13). http://www.trustech.org.uk/case-study/microvisk/.
    • (2012)
    • Warner, A.1
  • 51
    • 84882240253 scopus 로고    scopus 로고
    • MEMS sensor determines clots, MEMS Monthly Market Brief, iSuppli Corporation
    • J. Bouchaud, R. Nixon, MEMS sensor determines clots, MEMS Monthly Market Brief, iSuppli Corporation, 3 (2010) 13.
    • (2010) , vol.3 , pp. 13
    • Bouchaud, J.1    Nixon, R.2
  • 52
    • 84882259276 scopus 로고    scopus 로고
    • A portable cheap blood-clotting test, Technology Review 2008, <>, (last accessed 22.04.13).
    • G. Graham-Rowe, A portable cheap blood-clotting test, Technology Review 2008, <>, (last accessed 22.04.13). http://www.technologyreview.com/news/411164/a-portable-cheap-blood-clott ing-test/.
    • Graham-Rowe, G.1
  • 53
    • 0042830864 scopus 로고    scopus 로고
    • Point of care: diagnostics in hemostasis - the wrong direction?
    • Stief T.W., Fareed J. Point of care: diagnostics in hemostasis - the wrong direction?. Clin. Appl. Thromb. Haemost. 2003, 9:191-195.
    • (2003) Clin. Appl. Thromb. Haemost. , vol.9 , pp. 191-195
    • Stief, T.W.1    Fareed, J.2
  • 54
    • 66249112162 scopus 로고    scopus 로고
    • Point-of-care assessment of antiplatelet agents in the perioperative period: a review
    • Gibbs N.M. Point-of-care assessment of antiplatelet agents in the perioperative period: a review. Anaesth. Intensive Care 2009, 37:354-369.
    • (2009) Anaesth. Intensive Care , vol.37 , pp. 354-369
    • Gibbs, N.M.1
  • 55
    • 84882267161 scopus 로고    scopus 로고
    • CAP Today, Coagulation Analysers - Point of Care Self Monitoring , (last accessed 22.04.13).
    • CAP Today, Coagulation Analysers - Point of Care Self Monitoring 2011, <>, (last accessed 22.04.13). http://www.cap.org/apps/docs/cap_today/0511/0511_CAPTODAY_CoagAnalyzersP OC-selfMonitorGuide.pdf.
    • (2011)
  • 56
    • 17144396926 scopus 로고    scopus 로고
    • Platelet function testing in cardiovascular diseases
    • Michelson A.D. Platelet function testing in cardiovascular diseases. Circulation 2004, 110:489-493.
    • (2004) Circulation , vol.110 , pp. 489-493
    • Michelson, A.D.1
  • 57
    • 68549111033 scopus 로고    scopus 로고
    • Monitoring anticoagulation of primary haemostasis-estimation of platelet function in whole blood assays
    • Calatzis A., Leitner M., Panzer S. Monitoring anticoagulation of primary haemostasis-estimation of platelet function in whole blood assays. Hamostaseologie 2009, 29:279-284.
    • (2009) Hamostaseologie , vol.29 , pp. 279-284
    • Calatzis, A.1    Leitner, M.2    Panzer, S.3
  • 58
    • 10444228879 scopus 로고    scopus 로고
    • Platelet function analysis
    • Harrison P. Platelet function analysis. Blood Rev. 2005, 19:111-123.
    • (2005) Blood Rev. , vol.19 , pp. 111-123
    • Harrison, P.1
  • 59
    • 58249142988 scopus 로고    scopus 로고
    • Methods for the measurement of platelet function
    • Michelson A.D. Methods for the measurement of platelet function. Am. J. Cardiol. 2009, 103:20-26.
    • (2009) Am. J. Cardiol. , vol.103 , pp. 20-26
    • Michelson, A.D.1
  • 61
    • 77953191080 scopus 로고    scopus 로고
    • Platelet function testing and risk of bleeding complications
    • Ferreiro J.L., Sibbing D., Angiolillo D.J. Platelet function testing and risk of bleeding complications. Thromb. Haemost. 2010, 103:1128-1135.
    • (2010) Thromb. Haemost. , vol.103 , pp. 1128-1135
    • Ferreiro, J.L.1    Sibbing, D.2    Angiolillo, D.J.3
  • 62
    • 84882254014 scopus 로고    scopus 로고
    • Microfluidic device and method for fluid clotting time determination, Patent No. 2,201,365
    • S.C. De Ribes, P. Eguiguren, Microfluidic device and method for fluid clotting time determination, Patent No. 2,201,365 B1 (2006).
    • (2006) , vol.1 B
    • De Ribes, S.C.1    Eguiguren, P.2
  • 63
    • 77749305013 scopus 로고    scopus 로고
    • Development of a point of care lateral flow device for measuring human plasma fibrinogen
    • Dudek M.M., Lindahl T.L., Killard A.J. Development of a point of care lateral flow device for measuring human plasma fibrinogen. Anal. Chem. 2010, 82:2029-2035.
    • (2010) Anal. Chem. , vol.82 , pp. 2029-2035
    • Dudek, M.M.1    Lindahl, T.L.2    Killard, A.J.3
  • 64
    • 77958046234 scopus 로고    scopus 로고
    • Platelet aggregation monitoring with a newly developed quartz crystal microbalance system as an alternative to optical platelet aggregometry
    • Sinn S., Müller L., Drechsel H., Wandel M., Northoff H., Ziemer G., Wendel H.P., Gehring F.K. Platelet aggregation monitoring with a newly developed quartz crystal microbalance system as an alternative to optical platelet aggregometry. Analyst 2010, 135:2930-2938.
    • (2010) Analyst , vol.135 , pp. 2930-2938
    • Sinn, S.1    Müller, L.2    Drechsel, H.3    Wandel, M.4    Northoff, H.5    Ziemer, G.6    Wendel, H.P.7    Gehring, F.K.8
  • 65
    • 77954203063 scopus 로고    scopus 로고
    • On-chip aptamer-based sandwich assay for thrombin detection employing magnetic beads and quantum dots
    • Tennico Y.H., Hutanu D., Koesdjojo M.T., Bartel C.M., Remcho V.T. On-chip aptamer-based sandwich assay for thrombin detection employing magnetic beads and quantum dots. Anal. Chem. 2010, 82:5591-5597.
    • (2010) Anal. Chem. , vol.82 , pp. 5591-5597
    • Tennico, Y.H.1    Hutanu, D.2    Koesdjojo, M.T.3    Bartel, C.M.4    Remcho, V.T.5
  • 66
    • 75149121866 scopus 로고    scopus 로고
    • A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood
    • Tovar-Lopez F.J., Rosengarten G., Westein E., Khoshmanesh K., Jackson S.P., Mitchell A., Nesbitt W.S. A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood. Lab Chip 2010, 10:291-302.
    • (2010) Lab Chip , vol.10 , pp. 291-302
    • Tovar-Lopez, F.J.1    Rosengarten, G.2    Westein, E.3    Khoshmanesh, K.4    Jackson, S.P.5    Mitchell, A.6    Nesbitt, W.S.7
  • 67
    • 79954475267 scopus 로고    scopus 로고
    • Development of a fluorescent method for detecting the onset of coagulation in human plasma on microstructured lateral flow platforms
    • Dudek M.M., Kent N.J., Gu P., Fan Z.H., Killard A.J. Development of a fluorescent method for detecting the onset of coagulation in human plasma on microstructured lateral flow platforms. Analyst 2011, 136:1816-1825.
    • (2011) Analyst , vol.136 , pp. 1816-1825
    • Dudek, M.M.1    Kent, N.J.2    Gu, P.3    Fan, Z.H.4    Killard, A.J.5
  • 69
    • 77449129158 scopus 로고    scopus 로고
    • Point-of-care coagulation testing and transfusion algorithms
    • Enriquez L.J., Shore-Lesserson L. Point-of-care coagulation testing and transfusion algorithms. Br. J. Anaesth. 2009, 103:14-22.
    • (2009) Br. J. Anaesth. , vol.103 , pp. 14-22
    • Enriquez, L.J.1    Shore-Lesserson, L.2
  • 70
    • 77952106148 scopus 로고    scopus 로고
    • Development of a fluorescent anti-factor Xa assay to monitor unfractionated and low molecular weight heparins
    • Harris L.F., Castro-López V., Hammadi N., O'Donnell J.S., Killard A.J. Development of a fluorescent anti-factor Xa assay to monitor unfractionated and low molecular weight heparins. Talanta 2010, 81:1725-1730.
    • (2010) Talanta , vol.81 , pp. 1725-1730
    • Harris, L.F.1    Castro-López, V.2    Hammadi, N.3    O'Donnell, J.S.4    Killard, A.J.5
  • 71
    • 80052817045 scopus 로고    scopus 로고
    • Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays
    • Castro-López V., Harris L.F., O'Donnell J.S., Killard A.J. Quantification of unfractionated heparin in human plasma and whole blood by means of novel fluorogenic anti-FXa assays. J. Pharm. Biomed. Anal. 2011, 56:992-997.
    • (2011) J. Pharm. Biomed. Anal. , vol.56 , pp. 992-997
    • Castro-López, V.1    Harris, L.F.2    O'Donnell, J.S.3    Killard, A.J.4
  • 72
    • 84881144606 scopus 로고    scopus 로고
    • A microfluidic anti-Factor Xa assay device for point of care monitoring of anticoagulant therapy, Analyst, in press,
    • L.F. Harris, P. Rainey, V. Castro-Lopez, J.S. O'Donnell, A.J. Killard, A microfluidic anti-Factor Xa assay device for point of care monitoring of anticoagulant therapy, Analyst, in press, http://dx.doi.org/10.1039/C3AN00401E.
    • Harris, L.F.1    Rainey, P.2    Castro-Lopez, V.3    O'Donnell, J.S.4    Killard, A.J.5
  • 73
    • 0037403263 scopus 로고    scopus 로고
    • Conventional detection method of fibrinogen and fibrin degradation products using latex piezoelectric immunoassay
    • Aizawa H., Kurosawa S., Tozuka M., Park J.W., Kobayashi K., Tanaka H. Conventional detection method of fibrinogen and fibrin degradation products using latex piezoelectric immunoassay. Biosens. Bioelectron. 2003, 18:765-771.
    • (2003) Biosens. Bioelectron. , vol.18 , pp. 765-771
    • Aizawa, H.1    Kurosawa, S.2    Tozuka, M.3    Park, J.W.4    Kobayashi, K.5    Tanaka, H.6
  • 74
    • 0036605186 scopus 로고    scopus 로고
    • Empowering patients with point-of-care testing
    • Bissell M., Sanfilippo F. Empowering patients with point-of-care testing. Trends Biotechnol. 2002, 20:269-270.
    • (2002) Trends Biotechnol. , vol.20 , pp. 269-270
    • Bissell, M.1    Sanfilippo, F.2
  • 75
    • 70849108991 scopus 로고    scopus 로고
    • Drivers of biodiagnostic development
    • Giljohann D., Mirkin C.A. Drivers of biodiagnostic development. Nature 2009, 461-464.
    • (2009) Nature , pp. 461-464
    • Giljohann, D.1    Mirkin, C.A.2
  • 76
    • 33846987884 scopus 로고    scopus 로고
    • Aptamer based microsphere biosensor for thrombin detection
    • Zhu H., Suter J.D., White I.M., Fan X. Aptamer based microsphere biosensor for thrombin detection. Sensors 2006, 6:785-795.
    • (2006) Sensors , vol.6 , pp. 785-795
    • Zhu, H.1    Suter, J.D.2    White, I.M.3    Fan, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.