PncA gene expression and prediction factors on pyrazinamide resistance in Mycobacterium tuberculosis

Tuberculosis

Volumn 93, Issue 5, 2013, Pages 515-522

  Sheen, Patricia ^a   Lozano, Katherine ^a   Gilman, Robert H ^b   Valencia, Hugo J ^a   Loli, Sebastian ^a   Fuentes, Patricia ^a   Grandjean, Louis ^a,c   Zimic, Mirko ^a  

^a UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Mycobacterium tuberculosis; pncA expression level; POA efflux rate; PZA resistance; PZAse activity

Indexed keywords

BACTERIAL ENZYME; MESSENGER RNA; PYRAZINAMIDASE; PYRAZINAMIDE; PYRAZINOIC ACID; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME ASSAY; GENE EXPRESSION; GENE MUTATION; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PNCA GENE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE;

MYCOBACTERIUM TUBERCULOSIS; PNCA EXPRESSION LEVEL; POA EFFLUX RATE; PZA RESISTANCE; PZASE ACTIVITY;

AMIDOHYDROLASES; ANTITUBERCULAR AGENTS; DRUG RESISTANCE, BACTERIAL; GENES, BACTERIAL; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; PROMOTER REGIONS, GENETIC; PYRAZINAMIDE; RNA, BACTERIAL; RNA, MESSENGER;

EID: 84882257396     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2013.03.005     Document Type: Article

References (36)

1. Elizabeth L. Corbett, Catherine J. Watt, Neff Walker, Dermot Maher, Brian G. Williams, Mario C. Raviglione, and Christopher Dye The growing burden of tuberculosis: global trends and interactions with the HIV epidemic Arch Intern Med 163 9 2003 1009 1021
2. B.R. Bloom, and C.J. Murray Tuberculosis: commentary on a reemergent killer Science 257 5073 1992 1055 1064
3. WHO Management of chronic and multidrug-resistant cases. Treatment of tuberculosis: guidelines for national programmes 3rd ed. 2003 Jotto Associati s.a.s.- Biella-Italy Geneva 43 45
4. K. Konno, F.M. Feldmann, and W. McDermott Pyrazinamide susceptibility and amidase activity of tubercle bacilli Am Rev Respir Dis 95 3 1967 461 469
5. D.A. Mitchison The action of antituberculosis drugs in short-course chemotherapy Tubercle 66 3 1985 219 225
6. M.A. Steele, and R.M. Des Prez The role of pyrazinamide in tuberculosis chemotherapy Chest 94 4 1988 845 850
7. L. Vásquez-Campos, L. Asencios-Solis, E. Leo-Hurtado, N. Quispe-Torres, E. Salazar-Lindo, J. Bayona, and M.C. Becerra Drug resistance trends among previously treated tuberculosis patients in a national registry in Peru, 1994-2001 Int J Tuberc Lung Dis 8 4 2004 465 472
8. Y. Zhang, M.M. Wade, A. Scorpio, H. Zhang, and Z. Sun Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid J Antimicrob Chemother 52 5 2003 790 795
9. A. Scorpio, P. Lindholm-Levy, L. Heifets, R. Gilman, S. Siddiqi, and M. Cynamon Characterization of pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis Antimicrob Agents Chemother 41 3 1997 540 543
10. Y. Zhang, A. Scorpio, H. Nikaido, and Z. Sun Role of acid pH and deficient efflux of pyrazinoic acid in unique susceptibility of Mycobacterium tuberculosis to pyrazinamide J Bacteriol 181 7 1999 2044 2049
11. S.J. Cheng, L. Thibert, T. Sanchez, L. Heifets, and Y. Zhang pncA mutations as a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis: spread of a monoresistant strain in Quebec, Canada Antimicrob Agents Chemother 44 3 2000 528 532
12. Y. Zhang, and D. Mitchison The curious characteristics of pyrazinamide: a review Int J Tuberc Lung Dis 7 1 2003 6 21
13. Wanliang Shi, Xuelian Zhang, Xin Jiang, Haiming Ruan, Clifton E. Barry 3rd, Honghai Wang, Wenhong Zhang, and Ying Zhang Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis Science 333 6049 2011 1630 1632
14. K. Hirano, M. Takahashi, Y. Kazumi, Y. Fukasawa, and C. Abe Mutation in pncA is a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis Tuber Lung Dis 78 2 1997 117 122
15. L. Hou, D. Osei-Hyiaman, Z. Zhang, B. Wang, A. Yang, and K. Kano Molecular characterization of pncA gene mutations in Mycobacterium tuberculosis clinical isolates from China Epidemiol Infect 124 2 2000 227 232
16. M. Mestdagh, P.A. Fonteyne, L. Realini, R. Rossau, G. Jannes, W. Mijs, K.A. De Smet, F. Portaels, and E. Van den Eeckhout Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis Antimicrob Agents Chemother 43 9 1999 2317 2319
17. Soon Kew Park, Jung Yoo Lee, Chulhun Ludgerus Chang, Min Ki Lee, Han Chul Son, Cheol Min Kim, Hyun Jung Jang, Hee Kyung Park, and Seok Hoon Jeong pncA mutations in clinical Mycobacterium tuberculosis isolates from Korea BMC Infect Dis 1 2001 4
18. S. Sreevatsan, X. Pan, Y. Zhang, B.N. Kreiswirth, and J.M. Musser Mutations associated with pyrazinamide resistance in pncA of Mycobacterium tuberculosis complex organisms Antimicrob Agents Chemother 41 3 1997 636 640
19. P. Sheen, P. Ferrer, R.H. Gilman, J. López-Llano, P. Fuentes, E. Valencia, and M.J. Zimic Effect of pyrazinamidase activity on pyrazinamide resistance in Mycobacterium tuberculosis Tuberculosis 89 2 2009 109 113
20. M. Zimic, P. Fuentes, R.H. Gilman, A.H. Gutierrez, D. Kirwan, and P. Sheen Pyrazinoic acid efflux rate in Mycobacterium tuberculosis is a better proxy of pyrazinamide resistance Tuberculosis 92 1 2012 84 91
21. M. Zimic, S. Loli, R.H. Gilman, A. Gutierrez, P. Fuentes, M. Cotrina, D. Kirwan, and P. Sheen A new approach for pyrazinamide susceptibility testing in Mycobacterium tuberculosis Microb Drug Resist 2012
22. M.M. Wade, and Y. Zhang Mechanisms of drug resistance in Mycobacterium tuberculosis Front Biosci 9 2004 975 994
23. Z. Sun, and Y. Zhang Reduced pyrazinamidase activity and the natural resistance of Mycobacterium kansasii to the antituberculosis drug pyrazinamide Antimicrob Agents Chemother 43 3 1999 537 542
24. J.L. Chandler, and R.K. Gholson De novo biosynthesis of nicotinamide adenine dinucleotide in Escherichia coli: excretion of quinolinic acid by mutants lacking quinolinate phosphoribosyl transferase J Bacteriol 111 1 1972 98 102
25. J.W. Foster, and A.G. Moat Nicotinamide adenine dinucleotide biosynthesis and pyridine nucleotide cycle metabolism in microbial systems Microbiol Rev. 44 1 1980 83 105
26. D.F. Calbreath, and J.G. Joshi Inhibition of nicotinamidase by nicotinamide adenine dinucleotide J Biol Chem. 246 13 1971 4334 4339
27. M.W. Jewett, S. Jain, A.K. Linowski, A. Sarkar, and P.A. Rosa Molecular characterization of the Borrelia burgdorferi in vivo-essential protein PncA Microbiology 157 Pt 10 2011 2831 2840
28. L.G. Wayne Simple pyrazinamidase and urease tests for routine identification of mycobacteria Am Rev Respir Dis 109 1 1974 147 151
29. S.S. Trivedi, and S.G. Desai Pyrazinamidase activity of Mycobacterium tuberculosis - a test of sensitivity to pyrazinamide Tubercle 68 3 1987 221 224
30. A.S. Hadi, and S. Jefferey Procedures for the identification of multiple outliers in linear models J Am Stat Assoc 88 424 1993 1264 1272
31. M. Takakura, S. Kyo, T. Kanaya, M. Tanaka, and M. Inoue Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer Cancer Res. 58 7 1998 1558 1561
32. K.D. Robertson, E. Uzvolgyi, G. Liang, C. Talmadge, J. Sumegi, F.A. Gonzales, and P.A. Jones The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors Nucleic Acids Res 27 11 1999 2291 2298
33. K. Matsushita, S. Kobayashi, M. Kato, Y. Itoh, K. Okuyama, S. Sakiyama, and K. Isono Reduced messenger RNA expression level of p21 CIP1 in human colorectal carcinoma tissues and its association with p53 gene mutation Int J Cancer 69 4 1996 259 264
34. A.G. Nackley, S.A. Shabalina, I.E. Tchivileva, K. Satterfield, O. Korchynskyi, S.S. Makarov, W. Maixner, and L. Diatchenko Human catechol-O-methyltransferase haplotypes modulate protein expression by altering mRNA secondary structure Science 314 5807 2006 1930 1933
35. M. Lucassen, A. Schmidt, L.G. Eckerle, and H.O. Portner Mitochondrial proliferation in the permanent vs. temporary cold: enzyme activities and mRNA levels in Antarctic and temperate zoarcid fish Am J Physiol Regul Integr Comp Physiol 285 6 2003 R1410 R1420
36. U. Seedorf, E. Leberer, B.J. Kirschbaum, and D. Pette Neural control of gene expression in skeletal muscle. Effects of chronic stimulation on lactate dehydrogenase isoenzymes and citrate synthase Biochem J 239 1 1986 115 120