Immobilized enzymes to convert N-sulfo, N-acetyl heparosan to a critical intermediate in the production of bioengineered heparin

Journal of Biotechnology

Volumn 167, Issue 3, 2013, Pages 241-247

  Xiong, Jian ^a,b,c   Bhaskar, Ujjwal ^b,c   Li, Guoyun ^b,c   Fu, Li ^b,c   Li, Lingyun ^b,c   Zhang, Fuming ^b,c   Dordick, Jonathan S ^b,c   Linhardt, Robert J ^b,c,d  

^a YANGZHOU UNIVERSITY   (China)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^c Rensselaer Polytechnic Institute   (United States)

^d RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

2 O sulfotransferase; Aryl sulfotransferase IV; Heparosan; Immobilized enzymes

Indexed keywords

POLYSACCHARIDES; RECYCLING;

2-O-SULFOTRANSFERASE; ARYL SULFOTRANSFERASE IV; HEPAROSAN; IMMOBILIZED ENZYME;

ENZYME IMMOBILIZATION;

CHONDROITIN SULFATE; EPIMERASE; GLYCOSAMINOGLYCAN POLYSULFATE; HEPARIN; IMMOBILIZED ENZYME; N ACETYL HEPAROSAN; N SULFO HEPAROSAN; POLYSACCHARIDE; SULFOTRANSFERASE; UNCLASSIFIED DRUG; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; GLYCOSAMINOGLYCAN; N-ACETYLHEPAROSAN;

ARTICLE; BIOENGINEERING; CONTROLLED STUDY; DRUG CONFORMATION; DRUG MARKETING; DRUG SYNTHESIS; ENZYMATIC DEGRADATION; ENZYME IMMOBILIZATION; MORTALITY; NONHUMAN; PRIORITY JOURNAL; BIOREACTOR; BIOSYNTHESIS; CHEMISTRY; ENZYME STABILITY; METABOLISM; PROCEDURES;

SUIDAE;

BIOENGINEERING; BIOREACTORS; CARBOHYDRATE EPIMERASES; ENZYME STABILITY; ENZYMES, IMMOBILIZED; GLYCOSAMINOGLYCANS; HEPARIN; PHOSPHOADENOSINE PHOSPHOSULFATE; SULFOTRANSFERASES;

EID: 84882236877     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2013.06.018     Document Type: Article

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