MRI using targeted dendrimer contrast agents

Dendrimer-Based Nanomedicine

Volumn , Issue , 2008, Pages 255-287

  Swanson, Scott D ^a   Williams, Christopher R ^b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST AGENT;

MEDICAL NANOTECHNOLOGY;

EID: 84882011461     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.4032/9789814241182     Document Type: Chapter

References (50)

1. P. C. Lauterbur, Image formation by induced local interactions - examples employing nuclear magnetic-resonance, Nature, 242, 190-191, 1973.
2. V. R. Fuchs and H. C. Sox, Jr., Physicians views of the relative importance of thirty medical innovations, Health Aff (Millwood), 20, 30-42, 2001.
3. F. W. Wehrli, On the 2003 Nobel Prize in medicine or physiology awarded to Paul C. Lauterbur and Sir Peter Mansfield, Magn. Reson. Med., 51, 1-3, 2004.
4. G. Vogel, 2003 Nobel Prize. Physicists honored for their medical insights. Science, 302, 382-383, 2003.
5. J. Gore, Out of the shadows - MRI and the Nobel Prize, N. Engl. J. Med., 349, 2290-2292, 2003.
6. P. Mansfield and A. A. Maudsley, Medical imaging by NMR, Br. J. Radiol., 50, 188-194, 1977.
7. P. Mansfield, Snapshot magnetic resonance imaging (Nobel lecture), Angew. Chem. Int. Ed. Engl., 43, 5456-5464, 2004.
8. N. E. Rose and S. M. Gold, A comparison of accuracy between clinical examination and magnetic resonance imaging in the diagnosis of meniscal and anterior cruciate ligament tears, Arthroscopy, 12, 398-405, 1996.
9. F. Di Salle, E. Formisano, D. E. Linden, R. Goebel, S. Bonavita, A. Pepino, F. Smaltino, and G. Tedeschi, Exploring brain function with magnetic resonance imaging, Eur. J. Radiol., 30, 84-94, 1999.
10. M. Kriege, C. T. Brekelmans, C. Boetes, P. E. Besnard, H. M. Zonderland, I. M. Obdeijn, R. A. Manoliu, T. Kok, H. Peterse, M. M. Tilanus-Linthorst, S. H. Muller, S. Meijer, J. C. Oosterwijk, L. V. Beex, R. A. Tollenaar, H. J. de Koning, E. J. Rutgers, and J. G. Klijn, Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predisposition, N. Engl. J. Med., 351, 427-437, 2004.
11. S. K. Plevritis, A. W. Kurian, B. M. Sigal, B. L. Daniel, D. M. Ikeda, F. E. Stockdale, and A. M. Garber, Cost-effectiveness of screening BRCA1/2 mutation carriers with breast magnetic resonance imaging, Journal of the American Medical Association, 295, 2374-2384, 2006.
12. P. Caravan, J. J. Ellison, T. J. McMurry, and R. B. Lauffer, Gadolinium (III) Chelates as MRI contrast agents: Structure, dynamics, and applications, Chem. Rev., 99, 2293-2352, 1999.
13. C. W. Jung and P. Jacobs, Physical and chemical properties of superparamagnetic iron oxide MR contrast agents: Ferumoxides, ferumoxtran, ferumoxsil, Magn. Reson. Imaging., 13, 661-674, 1995.
14. G. J. Strijkers, W. J. Mulder, G. A. van Tilborg, and K. Nicolay, MRI contrast agents: Current status and future perspectives, Anticancer Agents Med. Chem., 7, 291-305, 2007.
15. A. K. Patri, J. F. Kukowska-Latallo, and J. R. Baker, Jr., Targeted drug delivery with dendrimers: Comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex, Advanced Drug Delivery Reviews, 57, 2203-2214, 2005.
16. E. M. Purcell, H. C. Torrey, and R. V. Pound, Resonance absorption by nuclear magnetic moments in a solid, Physical Review, 69, 37-38, 1946.
17. F. Bloch, W. W. Hansen, M. Packard, Nuclear induction, Physical Review, 69, 127-127, 1946.
18. A. Abragam, The Principles of Nuclear Magnetism, Oxford, Clarendon Press, 1961.
19. R. R. Ernst, G. Bodenhausen, and A. Wokaun, Principles of Nuclear Magnetic Resonance in One and Two Dimensions, Oxford, New York, Clarendon Press, Oxford University Press, 1988.
20. E. M. Haacke, Magnetic Resonance Imaging: Physical Principles and Sequence Design, New York, Wiley-Liss, 1999.
21. N. Bloembergen, E. M. Purcell, and R. V. Pound, Relaxation effects in nuclear magnetic resonance absorption, Physical Review, 73, 679-712, 1948.
22. S. H. Koenig, R. G. Bryant, K. Hallenga, and G. S. Jacob, Magnetic cross-relaxation among protons in protein solutions, Biochemistry, 17, 4348-4358, 1978.
23. R. A. Dwek, R. E. Richards, K. G. Morallee, E. Nieboer, R. J. Williams, and A. V. Xavier, The lanthanide cations as probes in biological systems. Proton relaxation enhancement studies for model systems and lysozyme, Eur. J. Biochem., 21, 204-209, 1971.
24. C. F. Geraldes, A. D. Sherry, R. D. Brown, 3rd, and S. H. Koenig, Magnetic field dependence of solvent proton relaxation rates induced by Gd3 and Mn2 complexes of various polyaza macrocyclic ligands: implications for NMR imaging, Magn. Reson. Med., 3, 242-250, 1986.
25. S. H. Koenig, C. Baglin, R. D. Brown, 3rd, and C. F. Brewer, Magnetic field dependence of solvent proton relaxation induced by Gd3 and Mn2 complexes, Magn. Reson. Med., 1, 496-501, 1984.
26. W. P. Cacheris, S. C. Quay, and S. M. Rocklage, The relationship between thermodynamics and the toxicity of gadolinium complexes, Magn. Reson. Imaging, 8, 467-481, 1990.
27. I. Solomon, Relaxation processes in a system of 2 spins, Physical Review, 99, 559-565, 1955.
28. N. Bloembergen and L. O. Morgan, Proton relaxation times in paramagnetic solutions effects of electron spin relaxation, Journal of Chemical Physics, 34, 842-850, 1961.
29. R. B. Lauffer, Paramagnetic metal-complexes as water proton relaxation agents for Nmr imaging - Theory and design, Chemical Reviews, 87, 901-927, 1987.
30. S. Laus, A. Sour, R. Ruloff, E. Toth, and A. E. Merbach, Rotational dynamics account for pH-dependent relaxivities of PAMAM dendrimeric, Gd-based potential MRI contrast agents, Chemistry-a European Journal, 11, 3064-3076, 2005.
31. G. M. Nicolle, E. Toth, H. Schmitt-Willich, B. Raduchel, and A. E. Merbach, The impact of rigidity and water exchange on the relaxivity of a dendritic MRI contrast agent, Chemistry-a European Journal, 8, 1040-1048, 2002.
32. P. A. Bottomley, T. H. Foster, R. E. Argersinger, and L. M. Pfeifer, Areview of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1-100 MHz: Dependence on tissue type, NMR frequency, temperature, species, excision, and age, Med. Phys., 11, 425-448, 1984.
33. S. D. Konda, M. Aref, M. Brechbiel, and E. C. Wiener, Development of a tumor-targeting MR contrast agent using the high-affinity folate receptor: Work in progress, Invest. Radiol., 35, 50-57, 2000.
34. H. Kobayashi, S. Kawamoto, T. Saga, N. Sato, T. Ishimori, J. Konishi, K. Ono, K. Togashi, and M. W. Brechbiel, Avidin-dendrimer-(1B4MGd)(254): A tumor-targeting therapeutic agent for gadolinium neutron capture therapy of intraperitoneal disseminated tumor which can be monitored by MRI, Bioconjugate Chemistry, 12, 587-593, 2001.
35. E. C. Wiener, M. W. Brechbiel, H. Brothers, R. L. Magin, O. A. Gansow, D. A. Tomalia, and P. C. Lauterbur, Dendrimer-based metal chelates: Anew class of magnetic resonance imaging contrast agents, Magn. Reson. Med., 31, 1-8, 1994.
36. H. Kobayashi, T. Saga, S. Kawamoto, N. Sato, A. Hiraga, T. Ishimori, J. Konishi, K. Togashi, and M. W. Brechbiel, Dynamic micromagnetic resonance imaging of liver micrometastasis in mice with a novel liver macromolecular magnetic resonance contrast agent DABAm64-(1B4M-Gd)(64), Cancer Research, 61, 4966-4970, 2001.
37. S. D. Konda, M. Aref, M. Brechbiel, and E. C. Wiener, Development of a tumor-targeting MR contrast agent using the high-affinity folate receptor - Work in progress, Investigative Radiology, 35, 50-57, 2000.
38. S. W. Choi and J. B. Mason, Folate and carcinogenesis: An integrated scheme, J. Nutr., 130, 129-132, 2000.
39. H. Kobayashi, N. Sato, S. Kawamoto, T. Saga, A. Hiraga, T. Ishimori, J. Konishi, K. Togashi, and M. W. Brechbiel, 3D MR angiography of intratumoral vasculature using a novel macromolecular MR contrast agent, Magnetic Resonance in Medicine, 46, 579-585, 2001.
40. H. Kobayashi, S. Kawamoto, R. A. Star, T. A. Waldmann, Y. Tagaya, and M. W. Brechbiel, Micro-magnetic resonance lymphangiography in mice using a novel dendrimer-based magnetic resonance imaging contrast agent, Cancer Res., 63, 271-276, 2003.
41. H. Xu, C. A. Regino, M. Bernardo, Y. Koyama, H. Kobayashi, P. L. Choyke, and M. W. Brechbiel, Toward improved syntheses of dendrimer-based magnetic resonance imaging contrast agents: New bifunctional diethylenetriamine-pentaacetic acid ligands and nonaqueous conjugation chemistry, J. Med. Chem., 50, 3185-3193, 2007.
42. J. W. Dear, H. Kobayashi, M. W. Brechbiel, and R. A. Star, Imaging acute renal failure with polyamine dendrimer-based MRI contrast agents, Nephron. Clin. Pract., 103, c45-49, 2006.
43. S. J. Wang, M. Brechbiel, and E. C. Wiener, Characteristics of a new MRI contrast agent prepared from polypropyleneimine dendrimers, generation 2, Investigative Radiology, 38, 662-668, 2003.
44. S. D. Swanson, A. K. Patri, J. F. Kukowska-Latilla, and J. R. Baker Jr., Targeted contrast using gadolinium labeled G5 dendrimers. In, ISMRM, Fourteenth Scientific Meeting and Exhibition, Seattle, WA, 2006.
45. S. H. Bai, C. Thomas, A. Rawat, and F. Ahsan Recent progress in dendrimer-based nanocarriers, Critical Reviews in Therapeutic Drug Carrier Systems, 23, 437-495, 2006.
46. V. Gajbhiye, P. V. Kumar, R. K. Tekade, and N. K. Jain, Pharmaceutical and biomedical potential of PEGylated dendrimers, Current Pharmaceutical Design, 13, 415-429, 2007.
47. S. D. Caruthers, S. A. Wickline, and G. M. Lanza, Nanotechnological applications in medicine, Current Opinion in Biotechnology, 18, 26-30, 2007.
48. D. A. Tomalia, L. A. Reyna, and S. Svenson, Dendrimers as multipurpose nanodevices for oncology drug delivery and diagnostic imaging, Biochemical Society Transactions, 35, 61-67, 2007.
49. S. Svenson and D. A. Tomalia, Commentary - Dendrimers in biomedical applications - reflections on the field, Advanced Drug Delivery Reviews, 57, 2106-2129, 2005.
50. J. L. Mynar, T. J. Lowery, D. E. Wemmer, A. Pines, and J. M. J. Frechet, Xenon biosensor amplification via dendrimer-cage supramolecular constructs, Journal of the American Chemical Society, 128, 6334-6335, 2006.