SCOPUS 정보 검색 플랫폼

Volumn 154, Issue 9, 2013, Pages 1542-1550

A phase 2, double-blind, randomized, placebo-controlled, dose-escalation study to evaluate the efficacy, safety, and tolerability of naloxegol in patients with opioid-induced constipation

(6) Webster, Lynn a Dhar, Sunita b Eldon, Michael c Masuoka, Lorianne d Lappalainen, Jaakko e Sostek, Mark e

a CRILifetree Clinical Research (United States)

b GENENTECH INC (United States)

c NEKTAR THERAPEUTICS (United States)

d AstraZeneca Pharmaceuticals ^*

e ASTRAZENECA (United Kingdom)

Author keywords

Constipation; Naloxegol; Naloxol; Naloxone; NKTR 118; Opioid

Indexed keywords

MORPHINE; NALOXEGOL; PLACEBO;

ABDOMINAL PAIN; ADULT; AREA UNDER THE CURVE; ARTICLE; COHORT ANALYSIS; CONSTIPATION; CONTROLLED STUDY; DIARRHEA; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; DYSPEPSIA; FEMALE; FLATULENCE; GASTROESOPHAGEAL REFLUX; HUMAN; MAJOR CLINICAL STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MULTICENTER STUDY; NAUSEA; PAIN; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH DISTENSION; TREATMENT DURATION; VOMITING;

CONSTIPATION; NALOXEGOL; NALOXOL; NALOXONE; NKTR-118; OPIOID;

ADULT; ANALGESICS, OPIOID; COHORT STUDIES; CONSTIPATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INTERNATIONAL COOPERATION; MALE; MIDDLE AGED; NALOXONE; NARCOTIC ANTAGONISTS; QUALITY OF LIFE; QUESTIONNAIRES; TIME FACTORS;

EID: 84881637428 PISSN: 03043959 EISSN: 18726623 Source Type: Journal
DOI: 10.1016/j.pain.2013.04.024 Document Type: Article

Times cited : (107)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.