-
1
-
-
0033991826
-
Oral naloxone reverses opioid-associated constipation
-
MEISSNER W, SCHMIDT U, HARTMANN M, KATH R, REINHART K. Oral naloxone reverses opioid-associated constipation. Pain 2000; 84: 105-109.
-
(2000)
Pain
, vol.84
, pp. 105-109
-
-
MEISSNER, W.1
SCHMIDT, U.2
HARTMANN, M.3
KATH, R.4
REINHART, K.5
-
2
-
-
0037249711
-
Opioid-induced bowel dysfunction: Pathophysiology and potential new therapies
-
KURZ A, SESSLER DI. Opioid-induced bowel dysfunction: pathophysiology and potential new therapies. Drugs 2003; 63: 649-671.
-
(2003)
Drugs
, vol.63
, pp. 649-671
-
-
KURZ, A.1
SESSLER, D.I.2
-
3
-
-
38849158390
-
Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients - current status and future options
-
HERBERT MK, HOLZER P. Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients - current status and future options. Clin Nutr 2008; 27: 25-41.
-
(2008)
Clin Nutr
, vol.27
, pp. 25-41
-
-
HERBERT, M.K.1
HOLZER, P.2
-
4
-
-
0024218061
-
Endogenous and exogenous opioids in the control of gastrointestinal motility and secretion
-
KROMER W. Endogenous and exogenous opioids in the control of gastrointestinal motility and secretion. Pharmacol Rev 1988; 40: 121-162.
-
(1988)
Pharmacol Rev
, vol.40
, pp. 121-162
-
-
KROMER W1
-
5
-
-
0029940621
-
Insights into opioid action in the intestinal tract
-
DE LUCA A, COUPAR IM. Insights into opioid action in the intestinal tract. Pharmacol Ther 1996; 69: 103-115.
-
(1996)
Pharmacol Ther
, vol.69
, pp. 103-115
-
-
DE LUCA, A.1
COUPAR, I.M.2
-
6
-
-
2342594524
-
Opioids and opioid receptors in the enteric nervous system: From a problem in opioid analgesia to a possible new prokinetic therapy in humans
-
HOLZER P. Opioids and opioid receptors in the enteric nervous system: From a problem in opioid analgesia to a possible new prokinetic therapy in humans. Neurosci Lett 2004; 361: 192-195.
-
(2004)
Neurosci Lett
, vol.361
, pp. 192-195
-
-
HOLZER P1
-
7
-
-
7944226027
-
The role of endogenous opiates in the control of gastrointestinal motility: Predictions from in vitro modelling
-
SANGER GJ, TULADHAR BR. The role of endogenous opiates in the control of gastrointestinal motility: Predictions from in vitro modelling. Neurogastroenterol Motil 2004; 16(Suppl 2): 38-45.
-
(2004)
Neurogastroenterol Motil
, vol.16
, Issue.SUPPL. 2
, pp. 38-45
-
-
SANGER, G.J.1
TULADHAR, B.R.2
-
8
-
-
33846782895
-
Treatment of opioid-induced gut dysfunction
-
HOLZER P. Treatment of opioid-induced gut dysfunction. Expert Opin Investig Drugs 2007; 16: 181-194.
-
(2007)
Expert Opin Investig Drugs
, vol.16
, pp. 181-194
-
-
HOLZER P1
-
9
-
-
0021894595
-
The central and peripheral influences of opioids on gastrointestinal propulsion
-
MANARA L, BIANCHETTI A. The central and peripheral influences of opioids on gastrointestinal propulsion. Annu Rev Pharmacol Toxicol 1985; 25: 249-273.
-
(1985)
Annu Rev Pharmacol Toxicol
, vol.25
, pp. 249-273
-
-
MANARA, L.1
BIANCHETTI, A.2
-
11
-
-
0035167473
-
Classes of enteric nerve cells in the guinea-pig small intestine
-
BROOKES SJH. Classes of enteric nerve cells in the guinea-pig small intestine. Anat Rec 2001; 262: 58-70.
-
(2001)
Anat Rec
, vol.262
, pp. 58-70
-
-
BROOKES SJH1
-
13
-
-
7944228025
-
The opioid system in the gastrointestinal tract
-
STERNINI C, PATIERNO S, SELMER IS, KIRCHGESSNER A. The opioid system in the gastrointestinal tract. Neurogastroenterol Motil 2004; 16(Suppl 2): 3-16.
-
(2004)
Neurogastroenterol Motil
, vol.16
, Issue.SUPPL. 2
, pp. 3-16
-
-
STERNINI, C.1
PATIERNO, S.2
SELMER, I.S.3
KIRCHGESSNER, A.4
-
14
-
-
7944230640
-
Function of opioids in the enteric nervous system
-
WOOD JD, GALLIGAN JJ. Function of opioids in the enteric nervous system. Neurogastroenterol Motil 2004; 16(Suppl 2): 17-28.
-
(2004)
Neurogastroenterol Motil
, vol.16
, Issue.SUPPL. 2
, pp. 17-28
-
-
WOOD, J.D.1
GALLIGAN, J.J.2
-
15
-
-
0344631516
-
Morphine contracts the guinea pig ileal circular muscle by interfering with a nitric oxide mediated tonic inhibition
-
LENARD L, HALMAI V, BARTHÓ L. Morphine contracts the guinea pig ileal circular muscle by interfering with a nitric oxide mediated tonic inhibition. Digestion 1999; 60: 562-566.
-
(1999)
Digestion
, vol.60
, pp. 562-566
-
-
LENARD, L.1
HALMAI, V.2
BARTHÓ, L.3
-
16
-
-
0018668605
-
Inhibition of stimulated fluid secretion in the rat small and large intestine by opiate agonists
-
BEUBLER E, LEMBECK F. Inhibition of stimulated fluid secretion in the rat small and large intestine by opiate agonists. Naunyn-Schmiedeberg's Arch Pharmacol 1979; 306: 113-118.
-
(1979)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.306
, pp. 113-118
-
-
BEUBLER, E.1
LEMBECK, F.2
-
17
-
-
0020965003
-
Antisecretory activity of opiates in vitro and in vivo in man
-
TURNBERG LA. Antisecretory activity of opiates in vitro and in vivo in man. Scand J Gastroenterol 1983; 84: 79-83.
-
(1983)
Scand J Gastroenterol
, vol.84
, pp. 79-83
-
-
TURNBERG LA1
-
18
-
-
0036177994
-
Involvement of μ- and κ-, but not δ-, opioid receptors in the peristaltic motor depression caused by endogenous and exogenous opioids in the guinea-pig intestine
-
SHAHBAZIAN A, HEINEMANN A, SCHMIDHAMMER H, BEUBLER E, HOLZER-PETSCHE U, HOLZER P. Involvement of μ- and κ-, but not δ-, opioid receptors in the peristaltic motor depression caused by endogenous and exogenous opioids in the guinea-pig intestine. Br J Pharmacol 2002; 135: 741-750.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 741-750
-
-
SHAHBAZIAN, A.1
HEINEMANN, A.2
SCHMIDHAMMER, H.3
BEUBLER, E.4
HOLZER-PETSCHE, U.5
HOLZER, P.6
-
19
-
-
0020599843
-
Morphine tissue levels and reduction of gastrointestinal transit in rats. Correlation supports primary action site in the gut
-
BIANCHI G, FERRETTI P, RECCHIA M, ROCCHETTI M, TAVANI A, MANARA L. Morphine tissue levels and reduction of gastrointestinal transit in rats. Correlation supports primary action site in the gut. Gastroenterology 1983; 85: 852-858.
-
(1983)
Gastroenterology
, vol.85
, pp. 852-858
-
-
BIANCHI, G.1
FERRETTI, P.2
RECCHIA, M.3
ROCCHETTI, M.4
TAVANI, A.5
MANARA, L.6
-
20
-
-
0036154291
-
Management of opioid-induced gastrointestinal effects in patients receiving palliative care
-
HERNDON CM, JACKSON KC, HALLIN PA. Management of opioid-induced gastrointestinal effects in patients receiving palliative care. Pharmacotherapy 2002; 22: 240-250.
-
(2002)
Pharmacotherapy
, vol.22
, pp. 240-250
-
-
HERNDON, C.M.1
JACKSON, K.C.2
HALLIN, P.A.3
-
21
-
-
0035849330
-
Randomised crossover trial of transdermal fentanyl and sustained release oral morphine for treating chronic non-cancer pain
-
ALLAN L, HAYS H, JENSEN NH, DE WAROUX BI, BOLT M, DONALD R, KALSO E . Randomised crossover trial of transdermal fentanyl and sustained release oral morphine for treating chronic non-cancer pain. Br Med J 2001; 322: 1154-1158.
-
(2001)
Br Med J
, vol.322
, pp. 1154-1158
-
-
ALLAN, L.1
HAYS, H.2
JENSEN, N.H.3
DE WAROUX, B.I.4
BOLT, M.5
DONALD, R.6
KALSO, E.7
-
22
-
-
36549022611
-
The involvement of the μ-opioid receptor in gastrointestinal pathophysiology: Therapeutic opportunities for antagonism at this receptor
-
DEHAVEN-HUDKINS DL, DEHAVEN RN, LITTLE PJ, TECHNER LM. The involvement of the μ-opioid receptor in gastrointestinal pathophysiology: Therapeutic opportunities for antagonism at this receptor. Pharmacol Ther 2008; 117: 162-187.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 162-187
-
-
DEHAVEN-HUDKINS, D.L.1
DEHAVEN, R.N.2
LITTLE, P.J.3
TECHNER, L.M.4
-
23
-
-
35548962696
-
Peripherally acting opioid antagonists in the treatment of opiate-related constipation: A systematic review
-
BECKER G, GALANDI D, BLUM HE. Peripherally acting opioid antagonists in the treatment of opiate-related constipation: A systematic review. J Pain Symptom Manage 2007; 34: 547-565.
-
(2007)
J Pain Symptom Manage
, vol.34
, pp. 547-565
-
-
BECKER, G.1
GALANDI, D.2
BLUM, H.E.3
-
24
-
-
7944221488
-
Preclinical studies of opioids and opioid antagonists on gastrointestinal function
-
GREENWOOD-VAN MEERVELD B, GARDNER CJ, LITTLE PJ, HICKS GA, DEHAVEN-HUDKINS DL. Preclinical studies of opioids and opioid antagonists on gastrointestinal function. Neurogastroenterol Motil 2004; 16(Suppl 2): 46-53.
-
(2004)
Neurogastroenterol Motil
, vol.16
, Issue.SUPPL. 2
, pp. 46-53
-
-
GREENWOOD-VAN MEERVELD, B.1
GARDNER, C.J.2
LITTLE, P.J.3
HICKS, G.A.4
DEHAVEN-HUDKINS, D.L.5
-
25
-
-
0026694257
-
Oral naloxone reduces constipation but not antinociception from oral morphine in the rat
-
JURNA I, KAISER R, KRETZ O, BALDAUF J. Oral naloxone reduces constipation but not antinociception from oral morphine in the rat. Neurosci Lett 1992; 142: 62-64.
-
(1992)
Neurosci Lett
, vol.142
, pp. 62-64
-
-
JURNA, I.1
KAISER, R.2
KRETZ, O.3
BALDAUF, J.4
-
26
-
-
0029878393
-
An investigation of the ability of oral naloxone to correct opioid-related constipation in patients with advanced cancer
-
SYKES NP. An investigation of the ability of oral naloxone to correct opioid-related constipation in patients with advanced cancer. Palliat Med 1996; 10: 135-144.
-
(1996)
Palliat Med
, vol.10
, pp. 135-144
-
-
SYKES NP1
-
27
-
-
0036153676
-
Low-dose oral naloxone reverses opioid-induced constipation and analgesia
-
LIU M, WITTBRODT E. Low-dose oral naloxone reverses opioid-induced constipation and analgesia. J Pain Symptom Manage 2002; 23: 48-53.
-
(2002)
J Pain Symptom Manage
, vol.23
, pp. 48-53
-
-
LIU, M.1
WITTBRODT, E.2
-
28
-
-
44649196037
-
Oral prolonged release (pr) oxycodone/naloxone combination reduces opioid-induced bowel dysfunction (OIBD)
-
MÜLLER-LISSNER S, LEYENDECKER P, RUCKES MC, FLEISCHER W, REIMER K . Oral prolonged release (pr) oxycodone/naloxone combination reduces opioid-induced bowel dysfunction (OIBD). Eur J Pain 2007; 11 (Suppl 1): S82.
-
(2007)
Eur J Pain
, vol.11
, Issue.SUPPL. 1
-
-
MÜLLER-LISSNER, S.1
LEYENDECKER, P.2
RUCKES, M.C.3
FLEISCHER, W.4
REIMER, K.5
-
29
-
-
0023945604
-
Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates
-
SIMPKINS JW, SMULKOWSKI M, DIXON R, TUTTLE R. Evidence for the delivery of narcotic antagonists to the colon as their glucuronide conjugates. J Pharmacol Exp Ther 1988; 244: 195-205.
-
(1988)
J Pharmacol Exp Ther
, vol.244
, pp. 195-205
-
-
SIMPKINS, J.W.1
SMULKOWSKI, M.2
DIXON, R.3
TUTTLE, R.4
-
30
-
-
33846849498
-
Effect of naloxone-3-glucuronide and N-methylnaloxone on the motility of the isolated rat colon after morphine
-
REBER P, BRENNEISEN R, FLOGERZI B, BATISTA C, NETZER P, SCHEURER U . Effect of naloxone-3-glucuronide and N-methylnaloxone on the motility of the isolated rat colon after morphine. Dig Dis Sci 2007; 52: 502-507.
-
(2007)
Dig Dis Sci
, vol.52
, pp. 502-507
-
-
REBER, P.1
BRENNEISEN, R.2
FLOGERZI, B.3
BATISTA, C.4
NETZER, P.5
SCHEURER, U.6
-
32
-
-
0020082071
-
Antagonism of gut, but not central effects of morphine with quaternary narcotic antagonists
-
RUSSELL J, BASS P, GOLDBERG LI, SCHUSTER CR, MERZ H. Antagonism of gut, but not central effects of morphine with quaternary narcotic antagonists. Eur J Pharmacol 1982; 78: 255-261.
-
(1982)
Eur J Pharmacol
, vol.78
, pp. 255-261
-
-
RUSSELL, J.1
BASS, P.2
GOLDBERG, L.I.3
SCHUSTER, C.R.4
MERZ, H.5
-
33
-
-
34047106723
-
The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone
-
BEATTIE DT, CHERUVU M, MAI N, O'KEEFE M, JOHNSON-RABIDOUX S, PETERSON C, KAUFMAN E, VICKERY R. The in vitro pharmacology of the peripherally restricted opioid receptor antagonists, alvimopan, ADL 08-0011 and methylnaltrexone. Naunyn-Schmiedeberg's Arch Pharmacol 2007; 375: 205-220.
-
(2007)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.375
, pp. 205-220
-
-
BEATTIE, D.T.1
CHERUVU, M.2
MAI, N.3
O'KEEFE, M.4
JOHNSON-RABIDOUX, S.5
PETERSON, C.6
KAUFMAN, E.7
VICKERY, R.8
-
34
-
-
33646455888
-
-
YUAN CS, ISRAEL RJ. Methylnaltrexone, a novel peripheral opioid receptor antagonist for the treatment of opioid side effects. Expert Opin. Investig. Drug 2006; 15: 541-552.
-
YUAN CS, ISRAEL RJ. Methylnaltrexone, a novel peripheral opioid receptor antagonist for the treatment of opioid side effects. Expert Opin. Investig. Drug 2006; 15: 541-552.
-
-
-
-
35
-
-
38049066540
-
-
REICHLE FM, CONZEN PF. Methylnaltrexone, a new peripheral μ-receptor antagonist for the prevention and treatment of opioid-induced extracerebral side effects. Curr Opin Investig Drugs 2008; 9: 90-100.
-
REICHLE FM, CONZEN PF. Methylnaltrexone, a new peripheral μ-receptor antagonist for the prevention and treatment of opioid-induced extracerebral side effects. Curr Opin Investig Drugs 2008; 9: 90-100.
-
-
-
-
36
-
-
0024407717
-
Variations in demethylation of N-methylnaltrexone in mice, rats, dogs, and humans
-
KOTAKE AN, KUWAHARA SK, BURTON E, MCCOY CE, GOLDBERG LI. Variations in demethylation of N-methylnaltrexone in mice, rats, dogs, and humans. Xenobiotica 1989; 19: 1247-1254.
-
(1989)
Xenobiotica
, vol.19
, pp. 1247-1254
-
-
KOTAKE, A.N.1
KUWAHARA, S.K.2
BURTON, E.3
MCCOY, C.E.4
GOLDBERG, L.I.5
-
37
-
-
17644395685
-
Tolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humans
-
YUAN CS, DOSHAN H, CHARNEY MR, O'CONNOR M, KARRISON T, MALECKAR SA, ISRAEL RJ, MOSS J. Tolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humans. J Clin Pharmacol 2005; 45: 538-546.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 538-546
-
-
YUAN, C.S.1
DOSHAN, H.2
CHARNEY, M.R.3
O'CONNOR, M.4
KARRISON, T.5
MALECKAR, S.A.6
ISRAEL, R.J.7
MOSS, J.8
-
38
-
-
34250619981
-
Reversal of opioid-induced bladder dysfunction by intravenous naloxone and methylnaltrexone
-
doi: 10.1038/ sj.cipt.6100164
-
ROSOW CE, GOMERY P, CHEN TY, STEFANOVICH P, STAMBLER N, ISRAEL R. Reversal of opioid-induced bladder dysfunction by intravenous naloxone and methylnaltrexone. Clin Pharmacol Ther 2007; doi: 10.1038/ sj.cipt.6100164.
-
Clin Pharmacol Ther
, vol.2007
-
-
ROSOW, C.E.1
GOMERY, P.2
CHEN, T.Y.3
STEFANOVICH, P.4
STAMBLER, N.5
ISRAEL, R.6
-
39
-
-
0034685012
-
Methylnaltrexone for reversal of constipation due to chronic methadone use: A randomized, controlled trial
-
YUAN CS, FOSS JF, O'CONNOR M, OSINSKI J, KARRISON T, MOSS J, ROIZEN MF. Methylnaltrexone for reversal of constipation due to chronic methadone use: A randomized, controlled trial. JAMA 2000; 283: 367-372.
-
(2000)
JAMA
, vol.283
, pp. 367-372
-
-
YUAN, C.S.1
FOSS, J.F.2
O'CONNOR, M.3
OSINSKI, J.4
KARRISON, T.5
MOSS, J.6
ROIZEN, M.F.7
-
40
-
-
43549095469
-
Alvimopan and COX-2 inhibition reverse opioid and inflammatory components of postoperative ileus
-
SCHMIDT J, STOFFELS B, NAZIR A, DEHAVEN-HUDKINS DL, BAUER AJ. Alvimopan and COX-2 inhibition reverse opioid and inflammatory components of postoperative ileus. Neurogastroenterol Motil 2008; 20: 689-699.
-
(2008)
Neurogastroenterol Motil
, vol.20
, pp. 689-699
-
-
SCHMIDT, J.1
STOFFELS, B.2
NAZIR, A.3
DEHAVEN-HUDKINS, D.L.4
BAUER, A.J.5
-
41
-
-
33746210072
-
The selective μ opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats
-
FUKUDA H, SUENAGA K, TSUCHIDA D, MANTYH CR, PAPPAS TN, HICKS GA, DEHAVEN-HUDKINS DL, TAKAHASHI T. The selective μ opioid receptor antagonist, alvimopan, improves delayed GI transit of postoperative ileus in rats. Brain Res 2006; 1102: 63-70.
-
(2006)
Brain Res
, vol.1102
, pp. 63-70
-
-
FUKUDA, H.1
SUENAGA, K.2
TSUCHIDA, D.3
MANTYH, C.R.4
PAPPAS, T.N.5
HICKS, G.A.6
DEHAVEN-HUDKINS, D.L.7
TAKAHASHI, T.8
-
42
-
-
0035543168
-
Alvimopan (ADL 8-2698) is a novel peripheral opioid antagonist
-
SCHMIDT WK. Alvimopan (ADL 8-2698) is a novel peripheral opioid antagonist. Am J Surg 2001; 182(Suppl): 27S-38S.
-
(2001)
Am J Surg
, vol.182
, Issue.SUPPL.
-
-
SCHMIDT WK1
-
43
-
-
16444366557
-
-
CAMILLERI M. Alvimopan, a selective peripherally acting μ-opioid antagonist. Neurogastroenterol. Motil 2004; 17: 157-65
-
CAMILLERI M. Alvimopan, a selective peripherally acting μ-opioid antagonist. Neurogastroenterol. Motil 2004; 17: 157-65
-
-
-
-
45
-
-
23644447886
-
Effect of alvimopan and codeine on gastrointestinal transit: A randomized controlled study
-
GONENNE J, CAMILLERI M, FERBER I, BURTON D, BAXTER K, KEYASHIAN K, FOSS J, WALLIN B, DU W, ZINSMEISTER AR. Effect of alvimopan and codeine on gastrointestinal transit: A randomized controlled study. Clin Gastroenterol Hepatol 2005; 3: 784-791.
-
(2005)
Clin Gastroenterol Hepatol
, vol.3
, pp. 784-791
-
-
GONENNE, J.1
CAMILLERI, M.2
FERBER, I.3
BURTON, D.4
BAXTER, K.5
KEYASHIAN, K.6
FOSS, J.7
WALLIN, B.8
DU, W.9
ZINSMEISTER, A.R.10
-
46
-
-
20144366569
-
Alvimopan: An oral, peripherally acting, μ-opioid receptor antagonist for the treatment of opioid-induced bowel dysfunction-a 21-day treatment-randomized clinical trial
-
PAULSON DM, KENNEDY DT, DONOVICK RA, CARPENTER RL, CHERUBINI M, TECHNER L, DU W, MA Y, SCHMIDT WK, WALLIN B, JACKSON D. Alvimopan: An oral, peripherally acting, μ-opioid receptor antagonist for the treatment of opioid-induced bowel dysfunction-a 21-day treatment-randomized clinical trial. J Pain 2005; 6: 184-192.
-
(2005)
J Pain
, vol.6
, pp. 184-192
-
-
PAULSON, D.M.1
KENNEDY, D.T.2
DONOVICK, R.A.3
CARPENTER, R.L.4
CHERUBINI, M.5
TECHNER, L.6
DU, W.7
MA, Y.8
SCHMIDT, W.K.9
WALLIN, B.10
JACKSON, D.11
-
47
-
-
45549109284
-
SNID0W J, PIERCE A, MORTENSEN E, KLEOUDIS C, CARTER E. Alvimopan, a peripherally acting μ-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction: Results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain
-
in press
-
WEBSTER L, JANSEN JP, PEPPIN J, LASKO B, IRVING G, MORLION B, SNID0W J, PIERCE A, MORTENSEN E, KLEOUDIS C, CARTER E. Alvimopan, a peripherally acting μ-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction: Results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain. Pain 2008; in press.
-
(2008)
Pain
-
-
WEBSTER, L.1
JANSEN, J.P.2
PEPPIN, J.3
LASKO, B.4
IRVING, G.5
MORLION, B.6
-
48
-
-
33845382939
-
Meta-analysis: Alvimopan vs. placebo in the treatment of post-operative ileus
-
TAN EK, CORNISH J, DARZI AW, TEKKIS PP. Meta-analysis: Alvimopan vs. placebo in the treatment of post-operative ileus. Aliment Pharmacol Ther 2007; 25: 47-57.
-
(2007)
Aliment Pharmacol Ther
, vol.25
, pp. 47-57
-
-
TAN, E.K.1
CORNISH, J.2
DARZI, A.W.3
TEKKIS, P.P.4
-
49
-
-
34247589358
-
Alvimopan, for postoperative ileus following bowel resection: A pooled analysis of phase III studies
-
DELANEY CP, WOLFF BG, VISCUSI ER, SENAGORE AJ, FORT JG, DU W, TECHNER L, WALLIN B. Alvimopan, for postoperative ileus following bowel resection: A pooled analysis of phase III studies. Ann Surg 2007; 245: 355-363.
-
(2007)
Ann Surg
, vol.245
, pp. 355-363
-
-
DELANEY, C.P.1
WOLFF, B.G.2
VISCUSI, E.R.3
SENAGORE, A.J.4
FORT, J.G.5
DU, W.6
TECHNER, L.7
WALLIN, B.8
-
50
-
-
42349114609
-
Pharmacokinetics of alvimopan and its metabolite in healthy volunteers and patients in postoperative ileus trials
-
doi: 10.1038/sj.clpt.6100292
-
FOSS JF, FISHER DM, SCHMITH VD. Pharmacokinetics of alvimopan and its metabolite in healthy volunteers and patients in postoperative ileus trials. Clin Pharmacol Ther 2007; doi: 10.1038/sj.clpt.6100292.
-
Clin Pharmacol Ther
, vol.2007
-
-
FOSS, J.F.1
FISHER, D.M.2
SCHMITH, V.D.3
-
51
-
-
0032253103
-
Peripheral effects of opioids in a model of chronic intestinal inflammation in mice
-
PUIG MM, POL O. Peripheral effects of opioids in a model of chronic intestinal inflammation in mice. J Pharmacol Exp Ther 1998; 287: 1068-1075.
-
(1998)
J Pharmacol Exp Ther
, vol.287
, pp. 1068-1075
-
-
PUIG, M.M.1
POL, O.2
-
52
-
-
0034763961
-
Inflammation enhances μ-opioid receptor transcription and expression in mice intestine
-
POL O, ALAMEDA F, PUIG MM. Inflammation enhances μ-opioid receptor transcription and expression in mice intestine. Mol Pharmacol 2001; 60: 894-899.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 894-899
-
-
POL, O.1
ALAMEDA, F.2
PUIG, M.M.3
-
53
-
-
0033950552
-
Effect of surgical stress on endogenous morphine and cytokine levels in the plasma after laparoscopoic or open cholecystectomy
-
YOSHIDA S, OHTA J, YAMASAKI K, KAMEI H, HARADA Y, YAHARA T, KAIBARA A, OZAKI K, TAJIRI T, SHIROUZU K. Effect of surgical stress on endogenous morphine and cytokine levels in the plasma after laparoscopoic or open cholecystectomy. Surg Endosc 2000; 14: 137-140.
-
(2000)
Surg Endosc
, vol.14
, pp. 137-140
-
-
YOSHIDA, S.1
OHTA, J.2
YAMASAKI, K.3
KAMEI, H.4
HARADA, Y.5
YAHARA, T.6
KAIBARA, A.7
OZAKI, K.8
TAJIRI, T.9
SHIROUZU, K.10
|