Unchanged mitochondrial organization and compartmentation of high-energy phosphates in creatine-deficient GAMT-/- mouse hearts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 4, 2013, Pages

  Branovets, Jelena ^a   Sepp, Mervi ^a   Kotlyarova, Svetlana ^a   Jepihhina, Natalja ^a   Sokolova, Niina ^a   Aksentijevic, Dunja ^b   Lygate, Craig A ^b   Neubauer, Stefan ^b   Vendelin, Marko ^a   Birkedal, Rikke ^a  

^a TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Confocal imaging; Creatine kinase shuttle; Guanidinoacetate methyltransferase; Intracellular diffusion barriers; Mitochondrial positioning; Respiration and ATPase kinetics

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; GUANIDINOACETATE METHYLTRANSFERASE; PHOSPHATE; PYRUVATE KINASE;

ANIMAL EXPERIMENT; ARTICLE; CELL COMPARTMENTALIZATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HEART FUNCTION; HEART MITOCHONDRION; MATHEMATICAL MODEL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM;

CONFOCAL IMAGING; CREATINE KINASE SHUTTLE; GUANIDINOACETATE METHYLTRANSFERASE; INTRACELLULAR DIFFUSION BARRIERS; MITOCHONDRIAL POSITIONING; RESPIRATION AND ATPASE KINETICS;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; CREATINE; CREATINE KINASE; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; FEMALE; GENOTYPE; GUANIDINOACETATE N-METHYLTRANSFERASE; HOMEOSTASIS; KINETICS; LANGUAGE DEVELOPMENT DISORDERS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA, HEART; MODELS, CARDIOVASCULAR; MOVEMENT DISORDERS; MYOCYTES, CARDIAC; PHENOTYPE; PYRUVATE KINASE;

EID: 84881631358     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00919.2012     Document Type: Article

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