Creatine kinase - Mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved

Journal of Clinical Investigation

Volumn 122, Issue 1, 2012, Pages 291-302

  Gupta, Ashish ^a   Akki, Ashwin ^a   Wang, Yibin ^b   Leppo, Michelle K ^a   Chacko, V P ^a   Foster, D Brian ^a   Caceres, Viviane ^a   Shi, Sa ^a,c   Kirk, Jonathan A ^a   Su, Jason ^a   Lai, Shenghan ^a,c   Paolocci, Nazareno ^a,d   Steenbergen, Charles ^a   Gerstenblith, Gary ^a   Weiss, Robert G ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HARBIN MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF PERUGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE KINASE ISOENZYME; CREATINE KINASE M; UNCLASSIFIED DRUG;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; EMBRYO; ENERGY METABOLISM; ENERGY RESOURCE; HEART FAILURE; HEART MUSCLE CONTRACTILITY; HEART STIMULATION; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STARVATION; SURVIVAL; THORACIC AORTA SURGERY; TRANSGENIC MOUSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CREATINE KINASE, MM FORM; DISEASE MODELS, ANIMAL; DOBUTAMINE; ENERGY METABOLISM; GENE EXPRESSION; HEART FAILURE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; PERFUSION; RECOMBINANT PROTEINS;

EID: 84855420869     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI57426     Document Type: Article

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