Inhibition of cytosolic and mitochondrial creatine kinase by siRNA in HaCaT- and HeLaS3-cells affects cell viability and mitochondrial morphology

Molecular and Cellular Biochemistry

Volumn 306, Issue 1-2, 2007, Pages 153-162

  Lenz, Holger ^a   Schmidt, Melanie ^a   Welge, Vivienne ^a   Kueper, Thomas ^a   Schlattner, Uwe ^c   Wallimann, Theo ^b   Elsässer, Hans Peter ^d   Wittern, Klaus Peter ^a   Wenck, Horst ^a   Staeb, Franz ^a   Blatt, Thomas ^a  

^a BEIERSDORF AG   (Germany)

^b ETH ZURICH   (Switzerland)

^c INSERM   (France)

^d PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Creatine; Creatine kinase; Mitochondria; siRNA

Indexed keywords

CASPASE; CREATINE KINASE BB; ISOENZYME; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL PROLIFERATION; CELL STRUCTURE; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME INHIBITION; HELA CELL; HUMAN; HUMAN CELL; KERATINOCYTE; METABOLITE; MITOCHONDRION; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN TARGETING;

CELL SURVIVAL; CREATINE KINASE, BB FORM; CREATINE KINASE, MITOCHONDRIAL FORM; CYTOSOL; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; ISOENZYMES; KERATINOCYTES; MITOCHONDRIA; PHOSPHOCREATINE; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 35548976628     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-007-9565-8     Document Type: Article

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