Cell-specific integration of nuclear receptor function at the genome

Wiley Interdisciplinary Reviews: Systems Biology and Medicine

Volumn 5, Issue 5, 2013, Pages 615-629

  Everett, Logan J ^a   Lazar, Mitchell A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; DEOXYRIBONUCLEASE I; DNA; ESTROGEN RECEPTOR ALPHA; HISTONE DEACETYLASE 3; LIVER X RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RETINOIC ACID RECEPTOR; RNA POLYMERASE II; TAMOXIFEN; TRANSCRIPTION FACTOR;

ADIPOGENESIS; ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; DISEASE COURSE; DRUG RECEPTOR BINDING; EPIGENETICS; GENETIC TRANSCRIPTION; GENOME; GENOMICS; LIGAND BINDING; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

CELL LINE, TUMOR; CHROMATIN; GENOME, HUMAN; HUMANS; MODELS, BIOLOGICAL; NUCLEOTIDE MOTIFS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84881627645     PISSN: 19395094     EISSN: 1939005X     Source Type: Journal    
DOI: 10.1002/wsbm.1231     Document Type: Article

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70. For additional reading on NR biology, we refer readers to the special issue of Pharmacological Reviews (December 2006, volume 58) published in collaboration with the International Union of Pharmacology, which contains comprehensive reviews on each NR subfamily. For additional information about genome-wide location analysis techniques beyond the reviews cited above, see the special ENCODE Project issues of Nature (September 2012, volume 489) and Genome Research (September 2012, volume 22). Genome-scale data and other resources related to the NR superfamily are hosted by the Nuclear Receptor Signaling Atlas (NURSA: www.nursa.org). An extensive catalogue of genome-wide data sets for NRs and their related cofactors and histone marks is available at: http://cistrome.dfci.harvard.edu/NR_Cistrome/.