Dihydrodipicolinate synthase from campylobacter jejuni: Kinetic mechanism of cooperative allosteric inhibition and inhibitor-induced substrate cooperativity

Biochemistry

Volumn 52, Issue 32, 2013, Pages 5454-5462

  Skovpen, Yulia V ^a   Palmer, David R J ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC INHIBITION; CAMPYLOBACTER JEJUNI; INHIBITION CONSTANTS; KINETIC EQUATIONS; LYSINE BIOSYNTHESIS; NON-LINEAR REGRESSION; PING-PONG MECHANISM; TETRAMERIC ENZYMES;

AMINO ACIDS; BIOCHEMISTRY; ENZYMES; INTEGRAL EQUATIONS; KINETIC PARAMETERS; KINETIC THEORY;

BACTERIA;

ASPARTATE SEMIALDEHYDE DEHYDROGENASE; BACTERIAL ENZYME; DIHYDRODIPICOLINATE SYNTHASE; LYSINE; PYRUVIC ACID; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING SITE; CAMPYLOBACTER JEJUNI; CATALYSIS; ENZYME INHIBITION; FEEDBACK SYSTEM; KINETICS; MOLECULE; NONHUMAN; PRIORITY JOURNAL;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ASPARTIC ACID; BACTERIAL PROTEINS; BINDING SITES; CAMPYLOBACTER JEJUNI; CATALYSIS; HYDRO-LYASES; KINETICS; LYSINE; MODELS, MOLECULAR; SUBSTRATE SPECIFICITY;

EID: 84881618917     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi400693w     Document Type: Article

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