-
1
-
-
0023152470
-
Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects
-
Davidson AB, Lee TH, Scanlon PD, Solway J, McFadden ER Jr, et al. (1987) Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects. Am Rev Respir Dis 135: 333-337.
-
(1987)
Am Rev Respir Dis
, vol.135
, pp. 333-337
-
-
Davidson, A.B.1
Lee, T.H.2
Scanlon, P.D.3
Solway, J.4
McFadden Jr., E.R.5
-
2
-
-
0023589276
-
Leukotrienes and airway responses
-
Drazen JM, Austen KF, (1987) Leukotrienes and airway responses. Am Rev Respir Dis 136: 985-998.
-
(1987)
Am Rev Respir Dis
, vol.136
, pp. 985-998
-
-
Drazen, J.M.1
Austen, K.F.2
-
3
-
-
3242807236
-
Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses
-
Kanaoka Y, Boyce JA, (2004) Cysteinyl leukotrienes and their receptors: cellular distribution and function in immune and inflammatory responses. J Immunol 173: 1503-1510.
-
(2004)
J Immunol
, vol.173
, pp. 1503-1510
-
-
Kanaoka, Y.1
Boyce, J.A.2
-
4
-
-
0026613070
-
Recovery of leukotriene E4 from the urine of patients with airway obstruction
-
Drazen JM, O'Brien J, Sparrow D, Weiss ST, Martins MA, et al. (1992) Recovery of leukotriene E4 from the urine of patients with airway obstruction. Am Rev Respir Dis 146: 104-108.
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 104-108
-
-
Drazen, J.M.1
O'Brien, J.2
Sparrow, D.3
Weiss, S.T.4
Martins, M.A.5
-
5
-
-
0026614209
-
Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects
-
Christie PE, Hawksworth R, Spur BW, Lee TH, (1992) Effect of indomethacin on leukotriene4-induced histamine hyperresponsiveness in asthmatic subjects. Am Rev Respir Dis 146: 1506-1510.
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 1506-1510
-
-
Christie, P.E.1
Hawksworth, R.2
Spur, B.W.3
Lee, T.H.4
-
6
-
-
0025284206
-
Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge
-
Wenzel SE, Larsen GL, Johnston K, Voelkel NF, Westcott JY, (1990) Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge. Am Rev Respir Dis 142: 112-119.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 112-119
-
-
Wenzel, S.E.1
Larsen, G.L.2
Johnston, K.3
Voelkel, N.F.4
Westcott, J.Y.5
-
7
-
-
0031871195
-
A placebo-controlled, dose-ranging study of montelukast, a cysteinyl leukotriene-receptor antagonist. Montelukast Asthma Study Group
-
Altman LC, Munk Z, Seltzer J, Noonan N, Shingo S, et al. (1998) A placebo-controlled, dose-ranging study of montelukast, a cysteinyl leukotriene-receptor antagonist. Montelukast Asthma Study Group. J Allergy Clin Immunol 102: 50-56.
-
(1998)
J Allergy Clin Immunol
, vol.102
, pp. 50-56
-
-
Altman, L.C.1
Munk, Z.2
Seltzer, J.3
Noonan, N.4
Shingo, S.5
-
8
-
-
0031754251
-
Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects
-
Hamilton A, Faiferman I, Stober P, Watson RM, O'Byrne PM, (1998) Pranlukast, a cysteinyl leukotriene receptor antagonist, attenuates allergen-induced early- and late-phase bronchoconstriction and airway hyperresponsiveness in asthmatic subjects. J Allergy Clin Immunol 102: 177-183.
-
(1998)
J Allergy Clin Immunol
, vol.102
, pp. 177-183
-
-
Hamilton, A.1
Faiferman, I.2
Stober, P.3
Watson, R.M.4
O'Byrne, P.M.5
-
9
-
-
0029915834
-
Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group
-
Israel E, Cohn J, Dube L, Drazen JM, (1996) Effect of treatment with zileuton, a 5-lipoxygenase inhibitor, in patients with asthma. A randomized controlled trial. Zileuton Clinical Trial Group. Jama 275: 931-936.
-
(1996)
Jama
, vol.275
, pp. 931-936
-
-
Israel, E.1
Cohn, J.2
Dube, L.3
Drazen, J.M.4
-
10
-
-
1542327670
-
Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis
-
Beller TC, Friend DS, Maekawa A, Lam BK, Austen KF, et al. (2004) Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis. Proc Natl Acad Sci U S A 101: 3047-3052.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3047-3052
-
-
Beller, T.C.1
Friend, D.S.2
Maekawa, A.3
Lam, B.K.4
Austen, K.F.5
-
11
-
-
8544261165
-
Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice
-
Beller TC, Maekawa A, Friend DS, Austen KF, Kanaoka Y, (2004) Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice. J Biol Chem 279: 46129-46134.
-
(2004)
J Biol Chem
, vol.279
, pp. 46129-46134
-
-
Beller, T.C.1
Maekawa, A.2
Friend, D.S.3
Austen, K.F.4
Kanaoka, Y.5
-
12
-
-
33646036422
-
Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation
-
Kim DC, Hsu FI, Barrett NA, Friend DS, Grenningloh R, et al. (2006) Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation. J Immunol 176: 4440-4448.
-
(2006)
J Immunol
, vol.176
, pp. 4440-4448
-
-
Kim, D.C.1
Hsu, F.I.2
Barrett, N.A.3
Friend, D.S.4
Grenningloh, R.5
-
13
-
-
0034730638
-
Characterization of the human cysteinyl leukotriene 2 receptor
-
Heise CE, O'Dowd BF, Figueroa DJ, Sawyer N, Nguyen T, et al. (2000) Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 275: 30531-30536.
-
(2000)
J Biol Chem
, vol.275
, pp. 30531-30536
-
-
Heise, C.E.1
O'Dowd, B.F.2
Figueroa, D.J.3
Sawyer, N.4
Nguyen, T.5
-
14
-
-
0033600291
-
Characterization of the human cysteinyl leukotriene CysLT1 receptor
-
Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, et al. (1999) Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 399: 789-793.
-
(1999)
Nature
, vol.399
, pp. 789-793
-
-
Lynch, K.R.1
O'Neill, G.P.2
Liu, Q.3
Im, D.S.4
Sawyer, N.5
-
15
-
-
69349105178
-
The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications
-
quiz 415-406
-
Austen KF, Maekawa A, Kanaoka Y, Boyce JA (2009) The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications. J Allergy Clin Immunol 124: 406-414; quiz 415-406.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 406-414
-
-
Austen, K.F.1
Maekawa, A.2
Kanaoka, Y.3
Boyce, J.A.4
-
16
-
-
55949121449
-
Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors
-
Maekawa A, Kanaoka Y, Xing W, Austen KF, (2008) Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors. Proc Natl Acad Sci U S A 105: 16695-16700.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16695-16700
-
-
Maekawa, A.1
Kanaoka, Y.2
Xing, W.3
Austen, K.F.4
-
17
-
-
70449700139
-
Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor
-
Paruchuri S, Tashimo H, Feng C, Maekawa A, Xing W, et al. (2009) Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor. J Exp Med 206: 2543-2555.
-
(2009)
J Exp Med
, vol.206
, pp. 2543-2555
-
-
Paruchuri, S.1
Tashimo, H.2
Feng, C.3
Maekawa, A.4
Xing, W.5
-
18
-
-
33646911541
-
Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell
-
Gurish MF, Boyce JA, (2006) Mast cells: ontogeny, homing, and recruitment of a unique innate effector cell. J Allergy Clin Immunol 117: 1285-1291.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 1285-1291
-
-
Gurish, M.F.1
Boyce, J.A.2
-
19
-
-
0033729622
-
Roles of mast cells and basophils in innate and acquired immunity
-
Wedemeyer J, Tsai M, Galli SJ, (2000) Roles of mast cells and basophils in innate and acquired immunity. Curr Opin Immunol 12: 624-631.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 624-631
-
-
Wedemeyer, J.1
Tsai, M.2
Galli, S.J.3
-
20
-
-
0141482048
-
Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R
-
Mellor EA, Frank N, Soler D, Hodge MR, Lora JM, et al. (2003) Expression of the type 2 receptor for cysteinyl leukotrienes (CysLT2R) by human mast cells: Functional distinction from CysLT1R. Proc Natl Acad Sci U S A 100: 11589-11593.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 11589-11593
-
-
Mellor, E.A.1
Frank, N.2
Soler, D.3
Hodge, M.R.4
Lora, J.M.5
-
21
-
-
0034933024
-
Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells
-
Mellor EA, Maekawa A, Austen KF, Boyce JA, (2001) Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells. Proc Natl Acad Sci U S A 98: 7964-7969.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7964-7969
-
-
Mellor, E.A.1
Maekawa, A.2
Austen, K.F.3
Boyce, J.A.4
-
22
-
-
47749133827
-
Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cells
-
Paruchuri S, Jiang Y, Feng C, Francis SA, Plutzky J, et al. (2008) Leukotriene E4 activates peroxisome proliferator-activated receptor gamma and induces prostaglandin D2 generation by human mast cells. J Biol Chem 283: 16477-16487.
-
(2008)
J Biol Chem
, vol.283
, pp. 16477-16487
-
-
Paruchuri, S.1
Jiang, Y.2
Feng, C.3
Francis, S.A.4
Plutzky, J.5
-
23
-
-
0037018105
-
Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists
-
Mellor EA, Austen KF, Boyce JA, (2002) Cysteinyl leukotrienes and uridine diphosphate induce cytokine generation by human mast cells through an interleukin 4-regulated pathway that is inhibited by leukotriene receptor antagonists. J Exp Med 195: 583-592.
-
(2002)
J Exp Med
, vol.195
, pp. 583-592
-
-
Mellor, E.A.1
Austen, K.F.2
Boyce, J.A.3
-
24
-
-
33747790575
-
Cutting edge: Interleukin 4-dependent mast cell proliferation requires autocrine/intracrine cysteinyl leukotriene-induced signaling
-
Jiang Y, Kanaoka Y, Feng C, Nocka K, Rao S, et al. (2006) Cutting edge: Interleukin 4-dependent mast cell proliferation requires autocrine/intracrine cysteinyl leukotriene-induced signaling. J Immunol 177: 2755-2759.
-
(2006)
J Immunol
, vol.177
, pp. 2755-2759
-
-
Jiang, Y.1
Kanaoka, Y.2
Feng, C.3
Nocka, K.4
Rao, S.5
-
25
-
-
0034057863
-
Protein kinase C binding partners
-
Jaken S, Parker PJ, (2000) Protein kinase C binding partners. Bioessays 22: 245-254.
-
(2000)
Bioessays
, vol.22
, pp. 245-254
-
-
Jaken, S.1
Parker, P.J.2
-
26
-
-
0032104245
-
The extended protein kinase C superfamily
-
Mellor H, Parker PJ, (1998) The extended protein kinase C superfamily. Biochem J 332 (Pt 2): 281-292.
-
(1998)
Biochem J
, vol.332
, Issue.Pt 2
, pp. 281-292
-
-
Mellor, H.1
Parker, P.J.2
-
27
-
-
0030987070
-
Regulation of protein kinase C
-
Newton AC, (1997) Regulation of protein kinase C. Curr Opin Cell Biol. 9: 161-167.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 161-167
-
-
Newton, A.C.1
-
28
-
-
0029060391
-
Protein kinase C and lipid signaling for sustained cellular responses
-
Nishizuka Y, (1995) Protein kinase C and lipid signaling for sustained cellular responses. Faseb J 9: 484-496.
-
(1995)
Faseb J
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
29
-
-
0023949864
-
Staurosporine inhibits protein kinase C and prevents phorbol ester-mediated leukotriene D4 receptor desensitization in RBL-1 cells
-
Vegesna RV, Wu HL, Mong S, Crooke ST, (1988) Staurosporine inhibits protein kinase C and prevents phorbol ester-mediated leukotriene D4 receptor desensitization in RBL-1 cells. Mol Pharmacol 33: 537-542.
-
(1988)
Mol Pharmacol
, vol.33
, pp. 537-542
-
-
Vegesna, R.V.1
Wu, H.L.2
Mong, S.3
Crooke, S.T.4
-
30
-
-
0025119751
-
Inhibitors of protein kinase C selectively enhanced leukotriene D4-induced calcium mobilization in differentiated U-937 cells
-
Winkler JD, Sarau HM, Foley JJ, Crooke ST, (1990) Inhibitors of protein kinase C selectively enhanced leukotriene D4-induced calcium mobilization in differentiated U-937 cells. Cell Signal 2: 427-437.
-
(1990)
Cell Signal
, vol.2
, pp. 427-437
-
-
Winkler, J.D.1
Sarau, H.M.2
Foley, J.J.3
Crooke, S.T.4
-
31
-
-
15744396122
-
Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling
-
Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, et al. (2005) Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. J Biol Chem 280: 8722-8732.
-
(2005)
J Biol Chem
, vol.280
, pp. 8722-8732
-
-
Naik, S.1
Billington, C.K.2
Pascual, R.M.3
Deshpande, D.A.4
Stefano, F.P.5
-
32
-
-
0035862168
-
The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells
-
Thodeti CK, Nielsen CK, Paruchuri S, Larsson C, Sjolander A, (2001) The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells. Exp Cell Res 262: 95-103.
-
(2001)
Exp Cell Res
, vol.262
, pp. 95-103
-
-
Thodeti, C.K.1
Nielsen, C.K.2
Paruchuri, S.3
Larsson, C.4
Sjolander, A.5
-
33
-
-
0037939677
-
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI
-
Kirshenbaum AS, Akin C, Wu Y, Rottem M, Goff JP, et al. (2003) Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI. Leuk Res 27: 677-682.
-
(2003)
Leuk Res
, vol.27
, pp. 677-682
-
-
Kirshenbaum, A.S.1
Akin, C.2
Wu, Y.3
Rottem, M.4
Goff, J.P.5
-
34
-
-
0033584240
-
T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro
-
Ochi H, Hirani WM, Yuan Q, Friend DS, Austen KF, et al. (1999) T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro. J Exp Med 190: 267-280.
-
(1999)
J Exp Med
, vol.190
, pp. 267-280
-
-
Ochi, H.1
Hirani, W.M.2
Yuan, Q.3
Friend, D.S.4
Austen, K.F.5
-
35
-
-
0036558287
-
Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells
-
Paruchuri S, Hallberg B, Juhas M, Larsson C, Sjolander A, (2002) Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells. J Cell Sci 115: 1883-1893.
-
(2002)
J Cell Sci
, vol.115
, pp. 1883-1893
-
-
Paruchuri, S.1
Hallberg, B.2
Juhas, M.3
Larsson, C.4
Sjolander, A.5
-
36
-
-
84856486368
-
Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression
-
Ng SW, Bakowski D, Nelson C, Mehta R, Almeyda R, et al. (2012) Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression. Nature 482: 111-115.
-
(2012)
Nature
, vol.482
, pp. 111-115
-
-
Ng, S.W.1
Bakowski, D.2
Nelson, C.3
Mehta, R.4
Almeyda, R.5
-
37
-
-
0037248043
-
Mast cells: beyond IgE
-
quiz 33
-
Boyce JA (2003) Mast cells: beyond IgE. J Allergy Clin Immunol 111: 24-32; quiz 33.
-
(2003)
J Allergy Clin Immunol
, vol.111
, pp. 24-32
-
-
Boyce, J.A.1
-
38
-
-
84865538716
-
Cysteinyl leukotriene receptors, old and new; implications for asthma
-
Laidlaw TM, Boyce JA, (2012) Cysteinyl leukotriene receptors, old and new; implications for asthma. Clin Exp Allergy 42: 1313-1320.
-
(2012)
Clin Exp Allergy
, vol.42
, pp. 1313-1320
-
-
Laidlaw, T.M.1
Boyce, J.A.2
-
39
-
-
37349081408
-
ATP-dependent transport of leukotrienes B4 and C4 by the multidrug resistance protein ABCC4 (MRP4)
-
Rius M, Hummel-Eisenbeiss J, Keppler D, (2008) ATP-dependent transport of leukotrienes B4 and C4 by the multidrug resistance protein ABCC4 (MRP4). J Pharmacol Exp Ther 324: 86-94.
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 86-94
-
-
Rius, M.1
Hummel-Eisenbeiss, J.2
Keppler, D.3
-
40
-
-
0037120054
-
Intracrine cysteinyl leukotriene receptor-mediated signaling of eosinophil vesicular transport-mediated interleukin-4 secretion
-
Bandeira-Melo C, Woods LJ, Phoofolo M, Weller PF, (2002) Intracrine cysteinyl leukotriene receptor-mediated signaling of eosinophil vesicular transport-mediated interleukin-4 secretion. J Exp Med 196: 841-850.
-
(2002)
J Exp Med
, vol.196
, pp. 841-850
-
-
Bandeira-Melo, C.1
Woods, L.J.2
Phoofolo, M.3
Weller, P.F.4
-
41
-
-
0023819252
-
Leukotriene D4-induced activation of protein kinase C in rat basophilic leukemia cells
-
Vegesna RV, Mong S, Crooke ST, (1988) Leukotriene D4-induced activation of protein kinase C in rat basophilic leukemia cells. Eur J Pharmacol 147: 387-396.
-
(1988)
Eur J Pharmacol
, vol.147
, pp. 387-396
-
-
Vegesna, R.V.1
Mong, S.2
Crooke, S.T.3
-
42
-
-
34547768330
-
PKC-dependent regulation of the receptor locus dominates functional consequences of cysteinyl leukotriene type 1 receptor activation
-
Deshpande DA, Pascual RM, Wang SW, Eckman DM, Riemer EC, et al. (2007) PKC-dependent regulation of the receptor locus dominates functional consequences of cysteinyl leukotriene type 1 receptor activation. Faseb J 21: 2335-2342.
-
(2007)
Faseb J
, vol.21
, pp. 2335-2342
-
-
Deshpande, D.A.1
Pascual, R.M.2
Wang, S.W.3
Eckman, D.M.4
Riemer, E.C.5
-
43
-
-
33845428771
-
CysLT1 receptor engagement induces activator protein-1- and NF-kappaB-dependent IL-8 expression
-
Thompson C, Cloutier A, Bosse Y, Thivierge M, Gouill CL, et al. (2006) CysLT1 receptor engagement induces activator protein-1- and NF-kappaB-dependent IL-8 expression. Am J Respir Cell Mol Biol 35: 697-704.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 697-704
-
-
Thompson, C.1
Cloutier, A.2
Bosse, Y.3
Thivierge, M.4
Gouill, C.L.5
-
44
-
-
0242413115
-
Leukotriene D4 mediates survival and proliferation via separate but parallel pathways in the human intestinal epithelial cell line Int 407
-
Paruchuri S, Sjolander A, (2003) Leukotriene D4 mediates survival and proliferation via separate but parallel pathways in the human intestinal epithelial cell line Int 407. J Biol Chem 278: 45577-45585.
-
(2003)
J Biol Chem
, vol.278
, pp. 45577-45585
-
-
Paruchuri, S.1
Sjolander, A.2
|