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Volumn 5, Issue 3, 2013, Pages 268-274

Current role of short-term intensive insulin strategies in newly diagnosed type 2 diabetes

Author keywords

cell function; Glycemic remission; Insulin therapy; Type 2 diabetes

Indexed keywords

GLICLAZIDE; GLUCOSE; INSULIN; METFORMIN;

EID: 84881553151     PISSN: 17530393     EISSN: 17530407     Source Type: Journal    
DOI: 10.1111/1753-0407.12054     Document Type: Review
Times cited : (10)

References (55)
  • 1
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010; 87: 4-14.
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 2
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) [published erratum appears in Lancet 1999;354:602]
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) [published erratum appears in Lancet 1999;354:602]. Lancet. 1998; 352: 837-853.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 3
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) [published erratum appears in Lancet 1998;352:1558]
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) [published erratum appears in Lancet 1998;352:1558]. Lancet. 1998; 352: 854-865.
    • (1998) Lancet , vol.352 , pp. 854-865
  • 5
    • 0030751382 scopus 로고    scopus 로고
    • Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment
    • Ilkova H, Glaser B, Tunckale A, Bagriacik N, Cerasi E. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care. 1997; 20: 1353-1356.
    • (1997) Diabetes Care , vol.20 , pp. 1353-1356
    • Ilkova, H.1    Glaser, B.2    Tunckale, A.3    Bagriacik, N.4    Cerasi, E.5
  • 6
    • 7444234167 scopus 로고    scopus 로고
    • Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function
    • Li Y, Xu W, Liao Z etal. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function. Diabetes Care. 2004; 27: 2597-2602.
    • (2004) Diabetes Care , vol.27 , pp. 2597-2602
    • Li, Y.1    Xu, W.2    Liao, Z.3
  • 7
    • 43849105857 scopus 로고    scopus 로고
    • Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: A multicentre randomised parallel-group trial
    • Weng J, Li Y, Xu W etal. Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: A multicentre randomised parallel-group trial. Lancet. 2008; 371: 1753-1760.
    • (2008) Lancet , vol.371 , pp. 1753-1760
    • Weng, J.1    Li, Y.2    Xu, W.3
  • 8
    • 2342587418 scopus 로고    scopus 로고
    • Short-term intensive insulin therapy in newly diagnosed type 2 diabetes
    • Ryan EA, Imes S, Wallace C. Short-term intensive insulin therapy in newly diagnosed type 2 diabetes. Diabetes Care. 2004; 27: 1028-1032.
    • (2004) Diabetes Care , vol.27 , pp. 1028-1032
    • Ryan, E.A.1    Imes, S.2    Wallace, C.3
  • 9
    • 84862832942 scopus 로고    scopus 로고
    • Short-term intensive therapy in newly diagnosed type 2 diabetes partially restores both insulin sensitivity and beta-cell function in subjects with long-term remission
    • Hu Y, Li L, Xu Y etal. Short-term intensive therapy in newly diagnosed type 2 diabetes partially restores both insulin sensitivity and beta-cell function in subjects with long-term remission. Diabetes Care. 2011; 34: 1848-1853.
    • (2011) Diabetes Care , vol.34 , pp. 1848-1853
    • Hu, Y.1    Li, L.2    Xu, Y.3
  • 10
    • 33745863033 scopus 로고    scopus 로고
    • Islet beta cell failure in type 2 diabetes
    • Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. J Clin Invest. 2006; 116: 1802-1812.
    • (2006) J Clin Invest , vol.116 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 11
    • 64649104158 scopus 로고    scopus 로고
    • Banting Lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
    • Defronzo RA. Banting Lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009; 58: 773-795.
    • (2009) Diabetes , vol.58 , pp. 773-795
    • Defronzo, R.A.1
  • 12
    • 0037283601 scopus 로고    scopus 로고
    • The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
    • Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. Diabetologia. 2003; 46: 3-19.
    • (2003) Diabetologia , vol.46 , pp. 3-19
    • Kahn, S.E.1
  • 13
  • 14
  • 15
    • 0028817815 scopus 로고
    • UK prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: A progressive disease [published erratum appears in Diabetes 1996; 45(11): 1655]
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. UK prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: A progressive disease [published erratum appears in Diabetes 1996; 45(11): 1655]. Diabetes. 1995; 44: 1249-1258.
    • (1995) Diabetes , vol.44 , pp. 1249-1258
  • 16
    • 0026731869 scopus 로고
    • Glucose toxicity
    • Yki-Jarvinen H. Glucose toxicity. Endocr Rev. 1992; 13: 415-431.
    • (1992) Endocr Rev , vol.13 , pp. 415-431
    • Yki-Jarvinen, H.1
  • 17
    • 34249682591 scopus 로고    scopus 로고
    • Beta-cell failure in diabetes and preservation by clinical treatment
    • Wajchenberg BL. Beta-cell failure in diabetes and preservation by clinical treatment. Endocr Rev. 2007; 28: 187-218.
    • (2007) Endocr Rev , vol.28 , pp. 187-218
    • Wajchenberg, B.L.1
  • 18
    • 0036314864 scopus 로고    scopus 로고
    • Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes?
    • Gerich JE. Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes? Diabetes. 2002; 51 (Suppl. 1): S117-121.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 1
    • Gerich, J.E.1
  • 19
    • 0026511753 scopus 로고
    • Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion
    • Leahy JL, Bonner-Weir S, Weir GC. Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion. Diabetes Care. 1992; 15: 442-455.
    • (1992) Diabetes Care , vol.15 , pp. 442-455
    • Leahy, J.L.1    Bonner-Weir, S.2    Weir, G.C.3
  • 20
    • 0033667824 scopus 로고    scopus 로고
    • Determinants of glucose toxicity and its reversibility in the pancreatic islet beta-cell line, HIT-T15
    • Gleason CE, Gonzalez M, Harmon JS, Robertson RP. Determinants of glucose toxicity and its reversibility in the pancreatic islet beta-cell line, HIT-T15. Am J Physiol Endocrinol Metab. 2000; 279: E997-1002.
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Gleason, C.E.1    Gonzalez, M.2    Harmon, J.S.3    Robertson, R.P.4
  • 22
    • 80054975337 scopus 로고    scopus 로고
    • Insulin improves beta-cell function in glucose-intolerant rat models induced by feeding a high-fat diet
    • Li HQ, Wang BP, Deng XL etal. Insulin improves beta-cell function in glucose-intolerant rat models induced by feeding a high-fat diet. Metabolism. 2011; 60: 1566-1574.
    • (2011) Metabolism , vol.60 , pp. 1566-1574
    • Li, H.Q.1    Wang, B.P.2    Deng, X.L.3
  • 23
    • 0032504211 scopus 로고    scopus 로고
    • Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells
    • Hugl SR, White MF, Rhodes CJ. Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. J Biol Chem. 1998; 273: 17771-17779.
    • (1998) J Biol Chem , vol.273 , pp. 17771-17779
    • Hugl, S.R.1    White, M.F.2    Rhodes, C.J.3
  • 24
    • 0041828484 scopus 로고    scopus 로고
    • Inflammatory mediators and islet beta-cell failure: A link between type 1 and type 2 diabetes
    • Donath MY, Storling J, Maedler K, Mandrup-Poulsen T. Inflammatory mediators and islet beta-cell failure: A link between type 1 and type 2 diabetes. J Mol Med. 2003; 81: 455-470.
    • (2003) J Mol Med , vol.81 , pp. 455-470
    • Donath, M.Y.1    Storling, J.2    Maedler, K.3    Mandrup-Poulsen, T.4
  • 25
    • 0041523870 scopus 로고    scopus 로고
    • Beneficial effects of insulin versus sulphonylurea on insulin secretion and metabolic control in recently diagnosed type 2 diabetic patients
    • Alvarsson M, Sundkvist G, Lager I etal. Beneficial effects of insulin versus sulphonylurea on insulin secretion and metabolic control in recently diagnosed type 2 diabetic patients. Diabetes Care. 2003; 26: 2231-2237.
    • (2003) Diabetes Care , vol.26 , pp. 2231-2237
    • Alvarsson, M.1    Sundkvist, G.2    Lager, I.3
  • 26
    • 56149118663 scopus 로고    scopus 로고
    • Beneficial effects of insulin on glycemic control and beta-cell function in newly diagnosed type 2 diabetes with severe hyperglycemia after short-term intensive insulin therapy
    • Chen HS, Wu TE, Jap TS, Hsiao LC, Lee SH, Lin HD. Beneficial effects of insulin on glycemic control and beta-cell function in newly diagnosed type 2 diabetes with severe hyperglycemia after short-term intensive insulin therapy. Diabetes Care. 2008; 31: 1927-1932.
    • (2008) Diabetes Care , vol.31 , pp. 1927-1932
    • Chen, H.S.1    Wu, T.E.2    Jap, T.S.3    Hsiao, L.C.4    Lee, S.H.5    Lin, H.D.6
  • 27
    • 84982315629 scopus 로고    scopus 로고
    • [The effects of early intensive therapy on islet beta cell function and long-term glycemia control in newly diagnosed type 2 diabetic patients with different fasting plasma glucose levels.]
    • in Chinese
    • Li YB, Zeng LY, Shi LX etal. [The effects of early intensive therapy on islet beta cell function and long-term glycemia control in newly diagnosed type 2 diabetic patients with different fasting plasma glucose levels.]. Zhonghua Nei Ke Za Zhi. 2010; 49: 9-13. (in Chinese).
    • (2010) Zhonghua Nei Ke Za Zhi , vol.49 , pp. 9-13
    • Li, Y.B.1    Zeng, L.Y.2    Shi, L.X.3
  • 28
    • 73449099308 scopus 로고    scopus 로고
    • Remission of hyperglycemia following intensive insulin therapy in newly diagnosed type 2 diabetic patients: A long-term follow-up study
    • Xu W, Li YB, Deng WP, Hao YT, Weng JP. Remission of hyperglycemia following intensive insulin therapy in newly diagnosed type 2 diabetic patients: A long-term follow-up study. Chin Med J. 2009; 122: 2554-2559.
    • (2009) Chin Med J , vol.122 , pp. 2554-2559
    • Xu, W.1    Li, Y.B.2    Deng, W.P.3    Hao, Y.T.4    Weng, J.P.5
  • 29
    • 0035136156 scopus 로고    scopus 로고
    • Near-normoglycaemic remission in African-Americans with Type 2 diabetes mellitus is associated with recovery of beta cell function
    • McFarlane SI, Chaiken RL, Hirsch S, Harrington P, Lebovitz HE, Banerji MA. Near-normoglycaemic remission in African-Americans with Type 2 diabetes mellitus is associated with recovery of beta cell function. Diabet Med. 2001; 18: 10-16.
    • (2001) Diabet Med , vol.18 , pp. 10-16
    • McFarlane, S.I.1    Chaiken, R.L.2    Hirsch, S.3    Harrington, P.4    Lebovitz, H.E.5    Banerji, M.A.6
  • 30
    • 0036068886 scopus 로고    scopus 로고
    • Normalization of plasma glucose concentration by insulin therapy improves insulin-stimulated glycogen synthesis in type 2 diabetes
    • Pratipanawatr T, Cusi K, Ngo P, Pratipanawatr W, Mandarino LJ, DeFronzo RA. Normalization of plasma glucose concentration by insulin therapy improves insulin-stimulated glycogen synthesis in type 2 diabetes. Diabetes. 2002; 51: 462-468.
    • (2002) Diabetes , vol.51 , pp. 462-468
    • Pratipanawatr, T.1    Cusi, K.2    Ngo, P.3    Pratipanawatr, W.4    Mandarino, L.J.5    DeFronzo, R.A.6
  • 31
    • 77749277261 scopus 로고    scopus 로고
    • Insulin therapy stimulates lipid synthesis and improves endocrine functions of adipocytes in dietary obese C57BL/6 mice
    • Chen X, Yu QQ, Zhu YH etal. Insulin therapy stimulates lipid synthesis and improves endocrine functions of adipocytes in dietary obese C57BL/6 mice. Acta Pharmacol Sin. 2010; 31: 341-346.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 341-346
    • Chen, X.1    Yu, Q.Q.2    Zhu, Y.H.3
  • 32
    • 81255135881 scopus 로고    scopus 로고
    • Changes in serum adiponectin concentrations and endothelial function after intensive insulin treatment in people with newly diagnosed type 2 diabetes: A pilot study
    • Li F, Zhao T, Wen X. Changes in serum adiponectin concentrations and endothelial function after intensive insulin treatment in people with newly diagnosed type 2 diabetes: A pilot study. Diabetes Res Clin Pract. 2011; 94: 186-192.
    • (2011) Diabetes Res Clin Pract , vol.94 , pp. 186-192
    • Li, F.1    Zhao, T.2    Wen, X.3
  • 33
    • 79960020593 scopus 로고    scopus 로고
    • Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats
    • Sun W, Bi Y, Liang H etal. Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats. Endocrine. 2011; 39: 235-241.
    • (2011) Endocrine , vol.39 , pp. 235-241
    • Sun, W.1    Bi, Y.2    Liang, H.3
  • 34
    • 84870472682 scopus 로고    scopus 로고
    • [Effects of early insulin therapy on sterol regulatory element binding protein 1 pathway and lipid accumulation in liver of type 2 diabetic rats.]
    • in Chinese
    • Sun WP, Bi Y, Liang H etal. [Effects of early insulin therapy on sterol regulatory element binding protein 1 pathway and lipid accumulation in liver of type 2 diabetic rats.]. Zhonghua Yi Xue Za Zhi. 2011; 91: 1809-1812. (in Chinese).
    • (2011) Zhonghua Yi Xue Za Zhi , vol.91 , pp. 1809-1812
    • Sun, W.P.1    Bi, Y.2    Liang, H.3
  • 35
    • 0141645381 scopus 로고    scopus 로고
    • [LysB3, GluB29] insulin: A novel insulin analog with enhanced beta-cell protective action
    • Rakatzi I, Seipke G, Eckel J. [LysB3, GluB29] insulin: A novel insulin analog with enhanced beta-cell protective action. Biochem Biophys Res Commun. 2003; 310: 852-859.
    • (2003) Biochem Biophys Res Commun , vol.310 , pp. 852-859
    • Rakatzi, I.1    Seipke, G.2    Eckel, J.3
  • 36
    • 2142822851 scopus 로고    scopus 로고
    • Insulin-like growth factors and pancreas beta cells
    • van Haeften TW, Twickler TB. Insulin-like growth factors and pancreas beta cells. Eur J Clin Invest. 2004; 34: 249-255.
    • (2004) Eur J Clin Invest , vol.34 , pp. 249-255
    • van Haeften, T.W.1    Twickler, T.B.2
  • 37
    • 35148859290 scopus 로고    scopus 로고
    • Exploring treatment strategies for type 2 diabetes
    • Bloomgarden ZT. Exploring treatment strategies for type 2 diabetes. Diabetes Care. 2007; 30: 2737-2745.
    • (2007) Diabetes Care , vol.30 , pp. 2737-2745
    • Bloomgarden, Z.T.1
  • 39
    • 0031961242 scopus 로고    scopus 로고
    • Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in type 2 diabetes mellitus: The 10-year follow-up of the Belfast Diet Study
    • Levy J, Atkinson AB, Bell PM, McCance DR, Hadden DR. Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in type 2 diabetes mellitus: The 10-year follow-up of the Belfast Diet Study. Diabet Med. 1998; 15: 290-296.
    • (1998) Diabet Med , vol.15 , pp. 290-296
    • Levy, J.1    Atkinson, A.B.2    Bell, P.M.3    McCance, D.R.4    Hadden, D.R.5
  • 40
    • 50149116384 scopus 로고    scopus 로고
    • Intensive insulin therapy in patients with type 2 diabetes
    • DeVries JH, Siegelaar S, Holleman F, Hoekstra JB. Intensive insulin therapy in patients with type 2 diabetes. Lancet. 2008; 372: 717.
    • (2008) Lancet , vol.372 , pp. 717
    • DeVries, J.H.1    Siegelaar, S.2    Holleman, F.3    Hoekstra, J.B.4
  • 41
    • 82755165018 scopus 로고    scopus 로고
    • Intensive glycaemic control for patients with type 2 diabetes: Systematic review with meta-analysis and trial sequential analysis of randomised clinical trials
    • Hemmingsen B, Lund SS, Gluud C etal. Intensive glycaemic control for patients with type 2 diabetes: Systematic review with meta-analysis and trial sequential analysis of randomised clinical trials. BMJ. 2011; 343: d6898.
    • (2011) BMJ , vol.343
    • Hemmingsen, B.1    Lund, S.S.2    Gluud, C.3
  • 42
    • 0034853485 scopus 로고    scopus 로고
    • Clinical review 135: The importance of beta-cell failure in the development and progression of type 2 diabetes
    • Kahn SE. Clinical review 135: The importance of beta-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab. 2011; 86: 4047-4058.
    • (2011) J Clin Endocrinol Metab , vol.86 , pp. 4047-4058
    • Kahn, S.E.1
  • 43
    • 3042714557 scopus 로고    scopus 로고
    • The burden of treatment failure in type 2 diabetes
    • Brown JB, Nichols GA, Perry A. The burden of treatment failure in type 2 diabetes. Diabetes Care. 2004; 27: 1535-1540.
    • (2004) Diabetes Care , vol.27 , pp. 1535-1540
    • Brown, J.B.1    Nichols, G.A.2    Perry, A.3
  • 44
    • 33644798145 scopus 로고    scopus 로고
    • Resistance to insulin therapy among patients and providers: Results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study
    • Peyrot M, Rubin RR, Lauritzen T etal. Resistance to insulin therapy among patients and providers: Results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study. Diabetes Care. 2005; 28: 2673-2679.
    • (2005) Diabetes Care , vol.28 , pp. 2673-2679
    • Peyrot, M.1    Rubin, R.R.2    Lauritzen, T.3
  • 45
    • 0036736185 scopus 로고    scopus 로고
    • When oral agents fail: Practical barriers to starting insulin
    • Korytkowski M. When oral agents fail: Practical barriers to starting insulin. Int J Obes Relat Metab Disord. 2002; 26 (Suppl. 3): S18-24.
    • (2002) Int J Obes Relat Metab Disord , vol.26 , Issue.SUPPL. 3
    • Korytkowski, M.1
  • 46
    • 84858126250 scopus 로고    scopus 로고
    • Effect of short-term intensive insulin therapy on quality of life in type 2 diabetes
    • Opsteen C, Qi Y, Zinman B, Retnakaran R. Effect of short-term intensive insulin therapy on quality of life in type 2 diabetes. J Eval Clin Pract. 2012; 18: 256-261.
    • (2012) J Eval Clin Pract , vol.18 , pp. 256-261
    • Opsteen, C.1    Qi, Y.2    Zinman, B.3    Retnakaran, R.4
  • 47
    • 49449103190 scopus 로고    scopus 로고
    • Improvement of cardiovascular risk factors in patients with type 2 diabetes after long-term continuous subcutaneous insulin infusion
    • Noh YH, Lee SM, Kim EJ etal. Improvement of cardiovascular risk factors in patients with type 2 diabetes after long-term continuous subcutaneous insulin infusion. Diabetes Metab Res Rev. 2008; 24: 384-391.
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 384-391
    • Noh, Y.H.1    Lee, S.M.2    Kim, E.J.3
  • 48
    • 0037357931 scopus 로고    scopus 로고
    • Induction of long-term normoglycemia without medication in Korean type 2 diabetes patients after continuous subcutaneous insulin infusion therapy
    • Park S, Choi SB. Induction of long-term normoglycemia without medication in Korean type 2 diabetes patients after continuous subcutaneous insulin infusion therapy. Diabetes Metab Res Rev. 2003; 19: 124-130.
    • (2003) Diabetes Metab Res Rev , vol.19 , pp. 124-130
    • Park, S.1    Choi, S.B.2
  • 49
    • 70349675747 scopus 로고    scopus 로고
    • Raskin P 2009. Insulin-based versus triple oral therapy for newly diagnosed type 2 diabetes: Which is better?
    • Lingvay I, Legendre JL, Kaloyanova PF, Zhang S, Adams-Huet B. Raskin P 2009. Insulin-based versus triple oral therapy for newly diagnosed type 2 diabetes: Which is better? Diabetes Care. 2009; 32: 1789-1795.
    • (2009) Diabetes Care , vol.32 , pp. 1789-1795
    • Lingvay, I.1    Legendre, J.L.2    Kaloyanova, P.F.3    Zhang, S.4    Adams-Huet, B.5
  • 50
    • 33745000699 scopus 로고    scopus 로고
    • Triple therapy in type 2 diabetes: Insulin glargine or rosiglitazone added to combination therapy of sulfonylurea plus metformin in insulin-naive patients
    • Rosenstock J, Sugimoto D, Strange P, Stewart JA, Soltes-Rak E, Dailey G. Triple therapy in type 2 diabetes: Insulin glargine or rosiglitazone added to combination therapy of sulfonylurea plus metformin in insulin-naive patients. Diabetes Care. 2006; 29: 554-559.
    • (2006) Diabetes Care , vol.29 , pp. 554-559
    • Rosenstock, J.1    Sugimoto, D.2    Strange, P.3    Stewart, J.A.4    Soltes-Rak, E.5    Dailey, G.6
  • 51
    • 77953356804 scopus 로고    scopus 로고
    • Gluttony, sloth and the metabolic syndrome: A roadmap to lipotoxicity
    • Unger RH, Scherer PE. Gluttony, sloth and the metabolic syndrome: A roadmap to lipotoxicity. Trends Endocrinol Metab. 2010; 21: 345-352.
    • (2010) Trends Endocrinol Metab , vol.21 , pp. 345-352
    • Unger, R.H.1    Scherer, P.E.2
  • 52
    • 52249114681 scopus 로고    scopus 로고
    • The islet beta-cell: Fuel responsive and vulnerable
    • Nolan CJ, Prentki M. The islet beta-cell: Fuel responsive and vulnerable. Trends Endocrinol Metab. 2008; 19: 285-291.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 285-291
    • Nolan, C.J.1    Prentki, M.2
  • 53
    • 84864270406 scopus 로고    scopus 로고
    • Basal insulin and cardiovascular and other outcomes in dysglycemia
    • Gerstein HC, Bosch J, Dagenais GR etal. Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med. 2012; 367: 319-328.
    • (2012) N Engl J Med , vol.367 , pp. 319-328
    • Gerstein, H.C.1    Bosch, J.2    Dagenais, G.R.3
  • 54
    • 77958192655 scopus 로고    scopus 로고
    • Cost-effectiveness of interventions to prevent and control diabetes mellitus: A systematic review
    • Li R, Zhang P, Barker LE, Chowdhury FM, Zhang X. Cost-effectiveness of interventions to prevent and control diabetes mellitus: A systematic review. Diabetes Care. 2010; 33: 1872-1894.
    • (2010) Diabetes Care , vol.33 , pp. 1872-1894
    • Li, R.1    Zhang, P.2    Barker, L.E.3    Chowdhury, F.M.4    Zhang, X.5
  • 55
    • 38949210220 scopus 로고    scopus 로고
    • Effect of a multifactorial intervention on mortality in type 2 diabetes
    • Gaede P, Lund-Andersen H, Parving HH, Pedersen O. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med. 2008; 358: 580-591.
    • (2008) N Engl J Med , vol.358 , pp. 580-591
    • Gaede, P.1    Lund-Andersen, H.2    Parving, H.H.3    Pedersen, O.4


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