Saturated fatty acid palmitate induces extracellular release of histone H3: A possible mechanistic basis for high-fat diet-induced inflammation and thrombosis

Biochemical and Biophysical Research Communications

Volumn 437, Issue 4, 2013, Pages 573-578

  Shrestha, Chandan ^a   Ito, Takashi ^a   Kawahara, Ko ichi ^b   Shrestha, Binita ^a   Yamakuchi, Munekazu ^a   Hashiguchi, Teruto ^a   Maruyama, Ikuro ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b OSAKA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

High fat diet; Histone H3; Inflammation; JNK; Palmitate; ROS

Indexed keywords

HISTONE H3; INTERCELLULAR ADHESION MOLECULE 1; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; SATURATED FATTY ACID; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ARTICLE; CHROMATIN; ENDOTHELIUM CELL; EXTRACELLULAR SPACE; INFLAMMATION; LIPID DIET; MACROPHAGE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; THROMBOSIS;

HIGH-FAT DIET; HISTONE H3; INFLAMMATION; JNK; PALMITATE; ROS;

ADIPOSE TISSUE; ANIMALS; CELL ADHESION; CELL LINE; CELL SURVIVAL; COAGULANTS; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; HISTONES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; MACROPHAGES; MALE; MAP KINASE KINASE 4; MICE; MICE, INBRED C57BL; PALMITIC ACID; REACTIVE OXYGEN SPECIES; THROMBOSIS; VASCULAR CELL ADHESION MOLECULE-1;

MURINAE; MUS;

EID: 84881551234     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.06.117     Document Type: Article

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