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Volumn 17, Issue 2, 2013, Pages 427-431

Induction of pro-inflammatory cytokine production in thymocytes by the immune response modifiers Imiquimod and Gardiquimod™

Author keywords

Cytokine; Immune response modifier; Interleukin 17; T cell; Thymus

Indexed keywords

ANTIVIRUS AGENT; GAMMA INTERFERON; GARDIQUIMOD; IMIQUIMOD; INTERLEUKIN 17; INTERLEUKIN 6; UNCLASSIFIED DRUG;

EID: 84881524257     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.06.023     Document Type: Article
Times cited : (25)

References (23)
  • 4
    • 33745848865 scopus 로고    scopus 로고
    • IL-17 production by thymocytes upon CD3 stimulation and costimulation with microbial factors
    • DOI 10.1016/j.cyto.2006.04.014, PII S1043466606001499
    • Hofstetter HH, Luhder F, Toyka KV, Gold R. IL-17 production by thymocytes upon CD3 stimulation and costimulation with microbial factors. Cytokine 2006;34: 184-97. (Pubitemid 44038574)
    • (2006) Cytokine , vol.34 , Issue.3-4 , pp. 184-197
    • Hofstetter, H.H.1    Luhder, F.2    Toyka, K.V.3    Gold, R.4
  • 5
    • 80155131752 scopus 로고    scopus 로고
    • The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells
    • Kim JS, Smith-Garvin JE, Koretzky GA, Jordan MS. The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells. J Exp Med 2011;208:2201-7.
    • (2011) J Exp Med , vol.208 , pp. 2201-2207
    • Kim, J.S.1    Smith-Garvin, J.E.2    Koretzky, G.A.3    Jordan, M.S.4
  • 6
    • 70349448417 scopus 로고    scopus 로고
    • Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation
    • Marks BR, Nowyhed HN, Choi JY, Poholek AC, Odegard JM, Flavell RA, et al. Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation. Nat Immunol 2009;10:1125-32.
    • (2009) Nat Immunol , vol.10 , pp. 1125-1132
    • Marks, B.R.1    Nowyhed, H.N.2    Choi, J.Y.3    Poholek, A.C.4    Odegard, J.M.5    Flavell, R.A.6
  • 7
    • 73349132687 scopus 로고    scopus 로고
    • Natural occurring IL-17 producing T cells regulate the initial phase of neutrophil mediated airway responses
    • Tanaka S, Yoshimoto T, Naka T, Nakae S, Iwakura Y, Cua D, et al. Natural occurring IL-17 producing T cells regulate the initial phase of neutrophil mediated airway responses. J Immunol 2009;183:7523-30.
    • (2009) J Immunol , vol.183 , pp. 7523-7530
    • Tanaka, S.1    Yoshimoto, T.2    Naka, T.3    Nakae, S.4    Iwakura, Y.5    Cua, D.6
  • 9
    • 80054837244 scopus 로고    scopus 로고
    • NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses
    • Hofmann J,Mair F,GreterM, Schmidt-SupprianM, Becher B.NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses. J Exp Med 2011;208:1917-29.
    • (2011) J Exp Med , vol.208 , pp. 1917-1929
    • Hofmann, J.1    Mair, F.2    Greter, M.3    Schmidt-Supprian, M.4    Becher, B.5
  • 11
    • 2442565738 scopus 로고    scopus 로고
    • Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the toll-like receptors
    • DOI 10.1074/jbc.M311618200
    • Nishiya T, DeFranco AL. Ligand-regulated chimeric receptor approach reveals distinctive subcellular localization and signaling properties of the Toll-like receptors. J Biol Chem 2004;279:19008-17. (Pubitemid 38623331)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.18 , pp. 19008-19017
    • Nishiya, T.1    DeFranco, A.L.2
  • 12
    • 77957680668 scopus 로고    scopus 로고
    • The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice
    • Ma F, Zhang J, Zhang C. The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in mice. Cell Mol Immunol 2010;7: 381-8.
    • (2010) Cell Mol Immunol , vol.7 , pp. 381-388
    • Ma, F.1    Zhang, J.2    Zhang, C.3
  • 13
    • 37848999304 scopus 로고    scopus 로고
    • TLR7 and TLR8 as targets in cancer therapy
    • Schon MP, Schon M. TLR7 and TLR8 as targets in cancer therapy. Oncogene 2008;27:190-9.
    • (2008) Oncogene , vol.27 , pp. 190-199
    • Schon, M.P.1    Schon, M.2
  • 14
    • 78249253334 scopus 로고    scopus 로고
    • Imiquimod-induced clearance of HPV is associated with normalization of immune cell counts in usual type vulvar intraepithelial neoplasia
    • TerlouA, van SetersM, KleinjanA, Heijmans-Antonissen C, Santegoets LA, BeckmannI, et al. Imiquimod-induced clearance ofHPV is associated with normalization of immune cell counts in usual type vulvar intraepithelial neoplasia. Int J Cancer 2010;127: 2831-40.
    • (2010) Int J Cancer , vol.127 , pp. 2831-2840
    • Terlou, A.1    Van Seters, M.2    Kleinjan, A.3    Heijmans-Antonissen, C.4    Santegoets, L.A.5    Beckmann, I.6
  • 15
    • 79956277591 scopus 로고    scopus 로고
    • Topical imiquimod treatment of aciclovir-resistant herpes simplex disease: Case series and literature review
    • Perkins N, Nisbet M, Thomas M. Topical imiquimod treatment of aciclovir-resistant herpes simplex disease: case series and literature review. Sex Transm Infect 2011;87:292-5.
    • (2011) Sex Transm Infect , vol.87 , pp. 292-295
    • Perkins, N.1    Nisbet, M.2    Thomas, M.3
  • 16
    • 79953065996 scopus 로고    scopus 로고
    • Topical imiquimod has therapeutic and immunomodulatory effects against intracranial tumors
    • Xiong Z, Ohlfest JR. Topical imiquimod has therapeutic and immunomodulatory effects against intracranial tumors. J Immunother 2011;34:264-9.
    • (2011) J Immunother , vol.34 , pp. 264-269
    • Xiong, Z.1    Ohlfest, J.R.2
  • 18
    • 33747622584 scopus 로고    scopus 로고
    • Masked oral prodrugs of toll-like receptor 7 agonists: A new approach for the treatment of infectious disease
    • Fletcher S, Steffy K, Averett D.Masked oral prodrugs of toll-like receptor 7 agonists: a new approach for the treatment of infectious disease. Curr Opin Investig Drugs 2006;7:702-8. (Pubitemid 44263174)
    • (2006) Current Opinion in Investigational Drugs , vol.7 , Issue.8 , pp. 702-708
    • Fletcher, S.1    Steffy, K.2    Averett, D.3
  • 19
    • 84861801523 scopus 로고    scopus 로고
    • Rorgammat+ innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice
    • Pantelyushin S, Haak S, Ingold B, Kulig P, Heppner FL, Navarini AA, et al. Rorgammat+ innate lymphocytes and gammadelta T cells initiate psoriasiform plaque formation in mice. J Clin Invest 2012;122:2252-6.
    • (2012) J Clin Invest , vol.122 , pp. 2252-2256
    • Pantelyushin, S.1    Haak, S.2    Ingold, B.3    Kulig, P.4    Heppner, F.L.5    Navarini, A.A.6
  • 20
    • 58849119199 scopus 로고    scopus 로고
    • Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology
    • Baenziger S, Heikenwalder M, Johansen P, Schlaepfer E, Hofer U, Miller RC, et al. Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology. Blood 2009;113:377-88.
    • (2009) Blood , vol.113 , pp. 377-388
    • Baenziger, S.1    Heikenwalder, M.2    Johansen, P.3    Schlaepfer, E.4    Hofer, U.5    Miller, R.C.6
  • 21
    • 79951723390 scopus 로고    scopus 로고
    • Stimulation of TLR7 prior to polymicrobial sepsis improves the immune control of the inflammatory response in adult mice
    • Koerner P, Traeger T,Mehmcke H, Cziupka K, KesslerW, Busemann A, et al. Stimulation of TLR7 prior to polymicrobial sepsis improves the immune control of the inflammatory response in adult mice. Inflamm Res 2011;60:271-9.
    • (2011) Inflamm Res , vol.60 , pp. 271-279
    • Koerner, P.1    Traeger, T.2    Mehmcke, H.3    Cziupka, K.4    Kessler, W.5    Busemann, A.6
  • 22
    • 79952779696 scopus 로고    scopus 로고
    • Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses
    • Billard MJ, Gruver AL, Sempowski GD. Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses. PLoS One 2011;6:e17940.
    • (2011) PLoS One , vol.6
    • Billard, M.J.1    Gruver, A.L.2    Sempowski, G.D.3
  • 23
    • 0028223194 scopus 로고
    • Sepsis-induced apoptosis of the thymocytes in mice
    • Wang SD, Huang KJ, Lin YS, Lei HY. Sepsis-induced apoptosis of the thymocytes in mice. J Immunol 1994;152:5014-21.
    • (1994) J Immunol , vol.152 , pp. 5014-5021
    • Wang, S.D.1    Huang, K.J.2    Lin, Y.S.3    Lei, H.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.