'Living' PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities

Nanotechnology

Volumn 24, Issue 35, 2013, Pages

  Chen, Hongwei ^a   Paholak, Hayley ^a   Ito, Masayuki ^b   Sansanaphongpricha, Kanokwan ^a   Qian, Wei ^b   Che, Yong ^b   Sun, Duxin ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b IMRA AMERICA INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMEDICAL APPLICATIONS; GOLD NANOPARTICLES; HETEROBIFUNCTIONAL PEGS; MULTI-FUNCTIONAL NANOPARTICLES; NEGATIVELY CHARGED; NON-SPECIFIC BINDING; POSITIVELY CHARGED; TARGETED NANOPARTICLE;

GOLD; LIGANDS; MEDICAL APPLICATIONS; METAL NANOPARTICLES; POLYETHYLENE GLYCOLS;

CELLS;

ARGINYL-GLYCYL-ASPARTIC ACID; GOLD; MACROGOL DERIVATIVE; NANOPARTICLE; OLIGOPEPTIDE;

CHEMISTRY; DRUG DELIVERY SYSTEM; GLIOBLASTOMA; HUMAN; MACROPHAGE; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; GLIOBLASTOMA; GOLD; HUMANS; MACROPHAGES; NANOPARTICLES; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS;

EID: 84881510558     PISSN: 09574484     EISSN: 13616528     Source Type: Journal    
DOI: 10.1088/0957-4484/24/35/355101     Document Type: Article

References (54)

1. Phillips M A, Gran M L and Peppas N A 2010 Targeted nanodelivery of drugs and diagnostics Nano Today 5 143
2. de la Zerda A, Bodapati S, Teed R, May S Y, Tabakman S M, Liu Z, Khuri-Yakub B T, Chen X Y, Dai H J and Gambhir S S 2012 Family of enhanced photoacoustic imaging agents for high-sensitivity and multiplexing studies in living mice ACS Nano 6 4694
3. Mickler F M, Mockl L, Ruthardt N, Ogris M, Wagner E and Brauchle C 2012 Tuning nanoparticle uptake: live-cell imaging reveals two distinct endocytosis mechanisms mediated by natural and artificial EGFR targeting ligand Nano Lett. 12 3417
4. Porta F, Lamers G E M, Morrhayim J, Chatzopoulou A, Schaaf M, den Dulk H, Backendorf C, Zink J I and Kros A 2013 Folic acid-modified mesoporous silica nanoparticles for cellular and nuclear targeted drug delivery Adv. Healthc. Mater. 2 281
5. Yue J, Liu S, Wang R, Hu X L, Xie Z G, Huang Y B and Jing X B 2012 Transferrin-conjugated micelles: enhanced accumulation and antitumor effect for transferrin-receptor-overexpressing cancer models Mol. Pharm. 9 1919
6. Yang L L et al 2009 Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging Small 5 235
7. Elias D R, Poloukhtine A, Popik V and Tsourkas A 2013 Effect of ligand density, receptor density, and nanoparticle size on cell targeting Nanomed. Nanotechnol. 9 194
8. Nie S M 2010 Understanding and overcoming major barriers in cancer nanomedicine Nanomedicine 5 523
9. Giljohann D A, Seferos D S, Daniel W L, Massich M D, Patel P C and Mirkin C A 2010 Gold nanoparticles for biology and medicine Angew. Chem. Int. Edn 49 3280
10. Doane T L and Burda C 2012 The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy Chem. Soc. Rev. 41 2885
11. Dykman L and Khlebtsov N 2012 Gold nanoparticles in biomedical applications: recent advances and perspectives Chem. Soc. Rev. 41 2256
12. Daniel M C and Astruc D 2004 Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology Chem. Rev. 104 293
13. Huang X, El-Sayed I H, Qian W and El-Sayed M A 2006 Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods J. Am. Chem. Soc. 128 2115 (Pubitemid 43277351)
14. Klein S, Petersen S, Taylor U, Rath D and Barcikowski S 2010 Quantitative visualization of colloidal and intracellular gold nanoparticles by confocal microscopy J. Biomed. Opt. 15 036015
15. Leduc C, Jung J M, Carney R R, Stellacci F and Lounis B 2011 Direct investigation of intracellular presence of gold nanoparticles via photothermal heterodyne imaging ACS Nano 5 2587
16. Qian X M, Peng X H, Ansari D O, Yin-Goen Q, Chen G Z, Shin D M, Yang L, Young A N, Wang M D and Nie S M 2008 In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags Nature Biotechnol. 26 83
17. Xie W, Qiu P H and Mao C B 2011 Bio-imaging, detection and analysis by using nanostructures as SERS substrates J. Mater. Chem. 21 5190
18. Rand D, Ortiz V, Liu Y A, Derdak Z, Wands J R, Taticek M and Rose-Petruck C 2011 Nanomaterials for x-ray imaging: gold nanoparticle enhancement of x-ray scatter imaging of hepatocellular carcinoma Nano Lett. 11 2678
19. Hirsch L R, Stafford R J, Bankson J A, Sershen S R, Rivera B, Price R E, Hazle J D, Halas N J and West J L 2003 Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance Proc. Natl Acad. Sci. USA 100 13549 (Pubitemid 37444779)
20. von Maltzahn G, Park J H, Lin K Y, Singh N, Schwoppe C, Mesters R, Berdel W E, Ruoslahti E, Sailor M J and Bhatia S N 2011 Nanoparticles that communicate in vivo to amplify tumour targeting Nature Mater. 10 545
21. 4 core@hybrid@Au shell nanocomposite for bimodal imaging and photothermal therapy Adv. Mater. 23 5392
22. Park K, Lee S, Kang E, Kim K, Choi K and Kwon I C 2009 New generation of multifunctional nanoparticles for cancer imaging and therapy Adv. Funct. Mater. 19 1553-66
23. Minelli C, Lowe S B and Stevens M M 2010 Engineering nanocomposite materials for cancer therapy Small 6 2336
24. Wang F, Wang Y C, Dou S, Xiong M H, Sun T M and Wang J 2011 Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells ACS Nano 5 3679
25. Choi C H J, Alabi C A, Webster P and Davis M E 2010 Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles Proc. Natl Acad. Sci. USA 107 1235
26. Qian W, Murakami M, Ichikawa Y and Che Y 2011 Highly efficient and controllable PEGylation of gold nanoparticles prepared by femtosecond laser ablation in water J. Phys. Chem. C 115 23293
27. Xia X H, Yang M X, Wang Y C, Zheng Y Q, Li Q G, Chen J Y and Xia Y N 2012 Quantifying the coverage density of poly(ethylene glycol) chains on the surface of gold nanostructures ACS Nano 6 512
28. Nagasaki Y 2011 Construction of a densely poly(ethylene glycol)-chain-tethered surface and its performance Polym. J. 43 949
29. Thierry B and Griesser H J 2012 Dense PEG layers for efficient immunotargeting of nanoparticles to cancer cells J. Mater. Chem. 22 8810
30. Walkey C D, Olsen J B, Guo H B, Emili A and Chan W C W 2012 Nanoparticle size and surface chemistry determine serum protein adsorption and macrophage uptake J. Am. Chem. Soc. 134 2139
31. Braunecker W A and Matyjaszewski K 2007 Controlled/living radical polymerization: features, developments, and perspectives Prog. Polym. Sci. 32 93 (Pubitemid 46201961)
32. Petersen S, Barchanski A, Taylor U, Klein S, Rath D and Barcikowski S 2011 Penetratin-conjugated gold nanoparticles - design of cell-penetrating nanomarkers by femtosecond laser ablation J. Phys. Chem. C 115 5152
33. Zeng H B, Du X W, Singh S C, Kulinich S A, Yang S K, He J P and Cai W P 2012 Nanomaterials via laser ablation/irradiation in liquid: a review Adv. Funct. Mater. 22 1333
34. Huang X H, Peng X H, Wang Y Q, Wang Y X, Shin D M, El-Sayed M A and Nie S M 2010 A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands ACS Nano 4 5887
35. Liu X O, Atwater M, Wang J H and Huo Q 2007 Extinction coefficient of gold nanoparticles with different sizes and different capping ligands Colloids Surf. B 58 3 (Pubitemid 46783417)
36. Kawaguchi S, Imai G, Suzuki J, Miyahara A and Kitano T 1997 Aqueous solution properties of oligo- and poly(ethylene oxide) by static light scattering and intrinsic viscosity Polymer 38 2885
37. Sylvestre J P, Poulin S, Kabashin A V, Sacher E, Meunier M and Luong J H T 2004 Surface chemistry of gold nanoparticles produced by laser ablation in aqueous media J. Phys. Chem. B 108 16864
38. Udenfrie S, Stein S, Bohlen P and Dairman W 1972 Fluorescamine - reagent for assay of amino-acids, peptides, proteins, and primary amines in picomole range Science 178 871
39. Gormley A J, Malugin A, Ray A, Robinson R and Ghandehari H 2011 Biological evaluation of RGDfK-gold nanorod conjugates for prostate cancer treatment J. Drug Target 19 915
40. Polyak D, Ryppa C, Eldar-Boock A, Ofek P, Many A, Licha K, Kratz F and Satchi-Fainaro R 2011 Development of PEGylated doxorubicin-E-[c(RGDfK)(2)] conjugate for integrin-targeted cancer therapy Polym. Adv. Technol. 22 103
41. de la Zerda A, Bodapati S, Teed R, May S Y, Tabakman S M, Liu Z, Khuri-Yakub B T, Chen X, Dai H and Gambhir S S 2012 Family of enhanced photoacoustic imaging agents for high-sensitivity and multiplexing studies in living mice ACS Nano 6 4694
42. Chen H W, Wang L Y, Yeh J, Wu X Y, Cao Z H, Wang Y A, Zhang M M, Yang L and Mao H 2010 Reducing non-specific binding and uptake of nanoparticles and improving cell targeting with an antifouling PEO-b-P gamma MPS copolymer coating Biomaterials 31 5397
43. Sancey L et al 2009 Clustering and internalization of integrin alpha(v)beta(3) with a tetrameric RGD-synthetic peptide Mol. Ther. 17 837
44. Byzova T V, Rabbani R, D'Souza S E and Plow E F 1998 Role of integrin alpha(v)beta(3) in vascular biology Thromb. Haemost. 80 726
45. Liu X S, Jin Q, Ji Y and Ji J 2012 Minimizing nonspecific phagocytic uptake of biocompatible gold nanoparticles with mixed charged zwitterionic surface modification J. Mater. Chem. 22 1916
46. Arvizo R R, Miranda O R, Thompson M A, Pabelick C M, Bhattacharya R, Robertson J D, Rotello V M, Prakash Y S and Mukherjee P 2010 Effect of nanoparticle surface charge at the plasma membrane and beyond Nano Lett. 10 2543
47. He C B, Hu Y P, Yin L C, Tang C and Yin C H 2010 Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles Biomaterials 31 3657
48. Pillai P P, Huda S, Kowalczyk B and Grzybowski B A 2013 Controlled pH stability and adjustable cellular uptake of mixed-charge nanoparticles J. Am. Chem. Soc. 135 6392
49. Cho E C, Au L, Zhang Q and Xia Y N 2010 The effects of size, shape, and surface functional group of gold nanostructures on their adsorption and internalization by cells Small 6 517
50. Frohlich E 2012 The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles Int. J. Nanomedicine 7 5577
51. Murthy A K, Stover R J, Hardin W G, Schramm R, Nie G D, Gourisankar S, Truskett T M, Sokolov K V and Johnston K P 2013 Charged gold nanoparticles with essentially zero serum protein adsorption in undiluted fetal bovine serum J. Am. Chem. Soc. 135 7799
52. Holmlin R E, Chen X X, Chapman R G, Takayama S and Whitesides G M 2001 Zwitterionic SAMs that resist nonspecific adsorption of protein from aqueous buffer Langmuir 17 2841
53. Chen S F, Yu F C, Yu Q M, He Y and Jiang S Y 2006 Strong resistance of a thin crystalline layer of balanced charged groups to protein adsorption Langmuir 22 8186 (Pubitemid 44412576)
54. Zhang L, Xue H, Gao C L, Carr L, Wang J N, Chu B C and Jiang S Y 2010 Imaging and cell targeting characteristics of magnetic nanoparticles modified by a functionalizable zwitterionic polymer with adhesive 3,4-dihydroxyphenyl-L- alanine linkages Biomaterials 31 6582