Transcription Factor TFAP2C Regulates Major Programs Required for Murine Fetal Germ Cell Maintenance and Haploinsufficiency Predisposes to Teratomas in Male Mice

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Schemmer, Jana ^a   Araúzo Bravo, Marcos J ^b   Haas, Natalie ^a   Schäfer, Sabine ^a,c   Weber, Susanne N ^a,d   Becker, Astrid ^a   Eckert, Dawid ^a,e   Zimmer, Andreas ^a   Nettersheim, Daniel ^a   Schorle, Hubert ^a  

^a UNIVERSITY OF BONN   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^c PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

^d SAARLAND UNIVERSITY   (Germany)

^e BIOBSERVE GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DNA METHYLTRANSFERASE 3B; KRUPPEL LIKE FACTOR 4; PROTEIN TFAP2C; SECRETED FRIZZLED RELATED PROTEIN 1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C KIT GENE; CANCER INCIDENCE; CANCER SUSCEPTIBILITY; CDK6 GENE; CDKN1A GENE; CELL DIFFERENTIATION; CELL FATE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DMRT1 GENE; DNMT3B GENE; DNMT3L GENE; DOWN REGULATION; EMBRYO; EMBRYONIC STEM CELL; EPIGENETICS; FETUS; FGF4 GENE; GENE; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENE TARGETING; GENETIC IDENTIFICATION; HAPLOINSUFFICIENCY; HETEROZYGOSITY; KLF4 GENE; MALE; MOUSE; NANOS3 GENE; NONHUMAN; PLURIPOTENT STEM CELL; PRIMORDIAL GERM CELL; PROTEIN BINDING; PROTEIN DEPLETION; SFRP1 GENE; SOMATIC CELL; TESTIS TERATOMA;

ANIMALS; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; CHROMATIN IMMUNOPRECIPITATION; CLUSTER ANALYSIS; EMBRYONIC STEM CELLS; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC PREDISPOSITION TO DISEASE; GERM CELLS; HAPLOINSUFFICIENCY; HETEROZYGOTE; MALE; MICE; MICE, KNOCKOUT; REPRODUCIBILITY OF RESULTS; RNA-BINDING PROTEINS; TERATOMA; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTIONAL ACTIVATION;

EID: 84881506685     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071113     Document Type: Article

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