Conserved epitopes dominate cross-CD8+ T-cell responses against influenza A H1N1 virus among asian populations

European Journal of Immunology

Volumn 43, Issue 8, 2013, Pages 2055-2069

  Liu, Jun ^a,b   Wu, Bin ^c   Zhang, Shihong ^a,d   Tan, Shuguang ^a,d   Sun, Yeping ^a   Chen, Zhujun ^a,e   Qin, Yuanfang ^c   Sun, Mingwei ^a,f   Shi, Guoli ^a,d   Wu, Ying ^a   Sun, Meiyi ^g   Liu, Na ^h   Ning, Kaida ^h   Ma, Ying ^a   Gao, Bin ^a   Yan, Jinghua ^a,d   Zhu, Fengcai ^c   Wang, Hua ^c   Gao, George F ^a,b,d,f,i  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^c JIANGSU PROVINCIAL CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e ANHUI AGRICULTURAL UNIVERSITY   (China)

^f UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^g Epigen Biotec   (China)

^h YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

CD8+ T cell; Conserved epitope; Immunodominance; Influenza A H1N1 virus; TCR usage

Indexed keywords

ANTIBODY; EPITOPE; HLA A2 ANTIGEN; INFLUENZA VACCINE; PEPTIDE; PLACEBO; PROTEOME; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADULT; ALLOGENEIC RESTRICTION; AMINO ACID SEQUENCE; ANTIBODY TITER; ANTIGENIC VARIATION; ANTIGENICITY; ANTIVIRAL ACTIVITY; ARTICLE; ASIAN; CAUCASIAN; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CROSS REACTION; FEMALE; GENETIC CONSERVATION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNOGENICITY; INFLUENZA A (H1N1); INFLUENZA VACCINATION; INFLUENZA VIRUS A H1N1; MAJOR CLINICAL STUDY; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; POPULATION; PRIORITY JOURNAL;

CD8+ T CELL; CONSERVED EPITOPE; IMMUNODOMINANCE; INFLUENZA A H1N1 VIRUS; TCR USAGE;

ADULT; ANTIGENIC VARIATION; ASIA; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; EPITOPES, T-LYMPHOCYTE; FEMALE; HLA-A2 ANTIGEN; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MALE; MIDDLE AGED; PROTEOME; RECEPTORS, ANTIGEN, T-CELL; VIRAL PROTEINS; YOUNG ADULT;

EID: 84881506605     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343417     Document Type: Article

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