Lack of association between interleukin-18 polymorphisms and rheumatoid arthritis;Ausência de associação entre os polimorfismos do gene interleucina-18 e artrite reumatoide

Revista Brasileira de Reumatologia

Volumn 53, Issue 2, 2013, Pages 199-205

  Farias, Ticiana Della Justina ^a   Do Cantoa, Luisa Matos ^a   Medeiros, Mayara Delagnelo ^a   Sereia, Aline Fernanda Rodrigues ^a   Back, Lia Kubelka Fernandes de Carlos ^a   De Mello, Filipe Martins ^b   Zimmermann, Adriana Fontes ^a   Pereira, Ivânio Alves ^a   Muniz, Yara Costa Netto ^a   Marrero, Andrea Rita ^a   De Souza, Ilíada Rainha ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Brazil; Cardiovascular diseases; Gene polymorphism; Interleukin 18; Rheumatoid arthritis

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; DNA; RHEUMATOID FACTOR;

ALLELE; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA EXTRACTION; DNA POLYMORPHISM; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HYPERTENSION; IL 18 GENE; MAJOR CLINICAL STUDY; PROTEIN BLOOD LEVEL; RHEUMATOID ARTHRITIS; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING HABIT;

ARTHRITIS, RHEUMATOID; CARDIOVASCULAR DISEASES; FEMALE; HUMANS; INTERLEUKIN-18; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 84881490278     PISSN: 04825004     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0482-50042013000200007     Document Type: Article

References (41)

1. Firestein GS. Envolving concepts or rheumatoid arthritis. Nature. 2003;423:356-61.
2. Klareskog L, Catrina AI, Paget S. Rheumatoid arthritis. Lancet. 2009;373 9664659-72
3. Alamanos Y, Drosos AA. Epidemiology of adult rheumatoid arthritis. Autoimmun Rev. 2005;4(3):130-6.
4. Harney S, Wordsworth BP. Genetic epidemiology of rheumatoid arthritis. Tissue Antigens. 2002;60(6):465-73.
5. Coenen MJ, Grefersen PK. Rheumatoid arthritis: a view of the current genetic landscape. Genes Immun. 2009;10(2):101-11.
6. de Souza AW, Mesquita Júnior D, Araújo JA, Catelan TT, Cruvinel W de M, Andrade LE, et al. Immune system: part III. The delicate balance of the immune system between tolerance and autoimmunity. Rev Bras Reumatol. 2010;50(6):665-79.
7. McInnes IB, Schett G. Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol. 2007;7(6):429-42.
8. Gabriel SE, Crowson CS. Risk factors for cardiovascular disease in rheumatoid arthritis. Curr Opin Rheumatol. 2012;24(2):171-6.
9. Aviña-Zubieta JA, Choi HK, Sadatsafavi M, Etminan M, Esdaile JM, Lacaille D. Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies. Arthritis Rheum. 2008;59(12):1690-7.
10. Boyer JF, Gourraud PA, Cantagrel A, Davignon JL, Constantin A. Traditional cardiovascular risk factors in rheumatoid arthritis: A meta-analysis. Jt, Bone Spine. 2011;78(2):179-83.
11. Bartoloni E, Alunno A, Bistoni O, Gerli R. Cardiovascular Risk in Rheumatoid Arthritis and Systemic Autoimmune Rheumatic Disorders: a Suggested Model of Preventive Strategy. Clin Rev Allergy Immunol. 2013;44(1):14-22.
12. Gonzalez-Juanatey C, Llorca J, Testa A, Revuelta J, Garcia- Porrua C, Gonzalez-Gay MA. Increased prevalence of severe subclinical atherosclerotic fi ndings in long-term treated rheumatoid arthritis patients without clinically evident atherosclerotic disease. Medicine (Baltimore). 2003;82(6):407-13.
13. Pereira IA, Borba EF. The role of infl ammation, humoral and cell mediated autoimmunity in the pathogenesis of atherosclerosis. Swiss Med Wkly. 2008;138(37-38):534-9.
14. Gracie JA, Forsey RJ, Chan WL, Gilmour A, Leung BP, Greer MR, et al. A proinfl ammatory role for IL-18 in rheumatoid arthritis. J Clin Invest. 1999;104(10):1393-401.
15. Giedraitis V, He B, Huang WX, Hillert J. Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol. 2001;112(1-2):146-52.
16. Thompson SR, Humphries SE. Interleukin-18 genetics and infl ammatory disease susceptibility. Genes Immun. 2007; 8(2):91-9.
17. Nurmohamed MT. Cardiovascular risk in rheumatoid arthritis. Autoimmun Rev. 2009;8(8):663-7.
18. Blankenberg S, Tiret L, Bickel C, Peetz D, Cambien F, Meyer J, et al. Interleukin-18 is a strong predictor of cardiovascular death in stable and unstable angina. Circulation. 2002;106:24-30.
19. Skurk T, Kolb H, Mũller-Scholze S, Röhrig K, Hauner H, Herder C. The proatherogenic cytokine interleukin-18 is secreted by human adipocytes. Eur J Endocrinol. 2005;152:863-8.
20. Hulthe J, McPheat W, Samnegård A, Tornvall P, Hamsten A, Eriksson P. Plasma interleukin (IL)-18 concentrations is elevated in patients with previous myocardial infarction and related to severity of coronary atherosclerosis independently of C-reactive protein and IL-6. Atherosclerosis. 2006;188(2):450-4.
21. Hernesniemi JA, Karhunen PJ, Oksala N, Kähönen M, Levula M, Rontu R, et al. Interleukin 18 gene promoter polymorphism: a link between hypertension and prehospital sudden cardiac death: the Helsinki Sudden Death Study. Eur Heart J. 2009;30(23):2939-46.
22. Zhang N, Yu JT, Yu NN, Lu RC, Ma T, Wang ND, et al. Interleukin-18 promoter polymorphisms and risk of ischemic stroke. Brain Res Bull. 2010;81(6):590-4.
23. Bis JC, Heckbert SR, Smith NL, Reiner AP, Rice K, Lumley T, et al. Variation in infl ammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke. Atherosclerosis. 2008;198(1):166-73.
24. Szeto CC, Chow KM, Poon PY, Kwan BC, Li PK. Association of interleukin-18 promoter polymorphism and atherosclerotic diseases in Chinese patients with diabetic nephropathy. Nephrology. 2009;14(6):606-12.
25. Sivalingam SP, Yoon KH, Koh DR, Fong KY. Single-nucleotide polymorphisms of the interleukin-18 gene promoter region in rheumatoid arthritis patients: protective effect of AA genotype. Tissue Antigens. 2003;62(2):498-504.
26. Sambrook J, Russel DW. Molecular cloning: a laboratory manual. 3.ed. New York: Cold Spring Harbour Laboratory Press; 2001.
27. Takada T, Suzuki E, Morohashi K, Gejyo F. Association of single nucleotide polymorphisms in the IL-18 gene with sarcoidosis in a Japanese population. Tissue Antigens. 2002;60(1):36-42.
28. Raymond M Rousset F. GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism. J Hered 1995; 86(3):248-9. Available from: http://genepop.curtin.edu. au/ [Access in May 2011].
29. Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 2001;68(4):978-89.
30. Woolf B. On estimating the relation between blood groups and disease. Ann Hum Genet 1955;19(4):251-3.
31. HDS EpiMax Table Calculator. Available from: http://www. healthstrategy.com/epiperl/epiperl.htm [Access in May 2011].
32. Pawlik A, Kurzawski M, Czerny B, Gawronska-Szklarz B, Drozdzik M, Herczynska M. Interleukin-18 promoter polymorphism in patients with rheumatoid arthritis. Tissue Antigens. 2006;67(5):415-8.
33. Rueda B, González-Gay MA, Mataran L, López-Nevot MA, Martín J. Interleukin-18-promoter polymorphisms are not relevant in rheumatoid arthritis. Tissue Antigens. 2005;65(6):544-8.
34. Ying B, Shi Y, Pan X, Song X, Huang Z, Niu Q, et al. Association of polymorphisms in the human IL-10 and IL-18 genes with rheumatoid arthritis. Mol Biol Rep. 2011;38(1):379-58.
35. Salzano FM, Freire-Maia SM. Problems in Human Biology. A Study of Brazilian Populations. Detroit: Wayne State University Press; 1970.
36. Pan HF, Leng RX, Ye DQ. Lack of association of interleukin-18 gene promoter -607 A/C polymorphism with susceptibility to autoimmune diseases: a meta-analysis. Lupus. 2011;20(9):945-51.
37. Mota LM, Cruz BA, Brenol CV, Pereira IA, Rezende-Fronza LS, Bertolo MB, et al. 2012 Brazilian Society of Rheumatology Consensus for the treatment of rheumatoid arthritis. Rev Bras Reumatol. 2012;52(2):152-74.
38. Boyer JF, Gourraud PA, Cantagrel A, Davignon JL, Constantin A. Traditional cardiovascular risk factors in rheumatoid arthritis: A meta-analysis. Jt, Bone Spine. 2011;78(2):179-83.
39. Torigoe, DY, Laurindo, IMM. Artrite Reumatoide e Doenças Cardiovasculares. Rev Bras Reumatol. 2006;46(1):60-6.
40. Evans J, Collins M, Jennings C, van der Merwe L, Söderström I, Olsson T, et al. The association of interleukin-18 genotype and serum levels with metabolic risk factors for cardiovascular disease. Eur J Endocrinol. 2007;157(5):633-40.
41. Hernesniemi JA, Anttila K, Nieminen T, Kähönen M, Mononen N, Nikus K, et al. IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease. Eur J Clin Invest. 2010;40(11):994-1001.