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Volumn 162, Issue 6, 2013, Pages 538-545

Association of BDNF gene polymorphisms with schizophrenia and clinical symptoms in a Chinese population

Author keywords

Association; Brain derived neurotrophic factor; Haplotype; Negative symptom; Polymorphism; Schizophrenia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CHLORPROMAZINE; CLOZAPINE; HALOPERIDOL; PERPHENAZINE; RISPERIDONE; SULPIRIDE;

EID: 84881486039     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.32183     Document Type: Article
Times cited : (28)

References (52)
  • 1
    • 79960088614 scopus 로고    scopus 로고
    • Childhood abuse, the BDNF-Val66Met polymorphism and adult psychotic-like experiences
    • Alemany S, Arias B, Aguilera M, Villa H, Moya J, Ibáñez MI., et al. 2011. Childhood abuse, the BDNF-Val66Met polymorphism and adult psychotic-like experiences. Br J Psychiatry 199(1):38-42.
    • (2011) Br J Psychiatry , vol.199 , Issue.1 , pp. 38-42
    • Alemany, S.1    Arias, B.2    Aguilera, M.3    Villa, H.4    Moya, J.5    Ibáñez, M.I.6
  • 2
    • 5744233877 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor
    • Binder DK, Scharfman HE. 2004. Brain-derived neurotrophic factor. Growth Factors 22:123-131.
    • (2004) Growth Factors , vol.22 , pp. 123-131
    • Binder, D.K.1    Scharfman, H.E.2
  • 3
    • 79951581460 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor: Findings in schizophrenia
    • Buckley PF, Pillai A, Howell KR. 2011. Brain-derived neurotrophic factor: Findings in schizophrenia. Curr Opin Psychiatry 24:122-127.
    • (2011) Curr Opin Psychiatry , vol.24 , pp. 122-127
    • Buckley, P.F.1    Pillai, A.2    Howell, K.R.3
  • 4
    • 64849093859 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met polymorphism: Association with psychopathological symptoms of schizophrenia
    • Chang HA, Lu RB, Shy MJ, Chang CC, Lee MS, Huang SY. 2009. Brain-derived neurotrophic factor Val66Met polymorphism: Association with psychopathological symptoms of schizophrenia? J Neuropsychiatry Clin Neurosci 21:30-37.
    • (2009) J Neuropsychiatry Clin Neurosci , vol.21 , pp. 30-37
    • Chang, H.A.1    Lu, R.B.2    Shy, M.J.3    Chang, C.C.4    Lee, M.S.5    Huang, S.Y.6
  • 5
    • 33644986866 scopus 로고    scopus 로고
    • Association between the brain-derived neurotrophic factor (BDNF) gene and schizophrenia in the Chinese population
    • Chen QY, Chen Q, Feng GY, Wan CL, Lindpaintner K, Wang LJ, et al. 2006. Association between the brain-derived neurotrophic factor (BDNF) gene and schizophrenia in the Chinese population. Neurosci Lett 397:285-290.
    • (2006) Neurosci Lett , vol.397 , pp. 285-290
    • Chen, Q.Y.1    Chen, Q.2    Feng, G.Y.3    Wan, C.L.4    Lindpaintner, K.5    Wang, L.J.6
  • 6
    • 79953272270 scopus 로고    scopus 로고
    • Association study of catechol-O-methyltransferase gene polymorphisms with schizophrenia and psychopathological symptoms in Han Chinese
    • Chen CY, Lu RB, Yeh YW, Shih MC, Huang SY. 2011. Association study of catechol-O-methyltransferase gene polymorphisms with schizophrenia and psychopathological symptoms in Han Chinese. Genes Brain Behav 10(3):316-324.
    • (2011) Genes Brain Behav , vol.10 , Issue.3 , pp. 316-324
    • Chen, C.Y.1    Lu, R.B.2    Yeh, Y.W.3    Shih, M.C.4    Huang, S.Y.5
  • 7
    • 0041857847 scopus 로고    scopus 로고
    • Pedigree disequilibrium tests for multilocus haplotypes
    • Dudbridge F. 2003. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 25(2):115-121.
    • (2003) Genet Epidemiol , vol.25 , Issue.2 , pp. 115-121
    • Dudbridge, F.1
  • 8
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F. 2008. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Human Heredity 66(2):87-98.
    • (2008) Human Heredity , vol.66 , Issue.2 , pp. 87-98
    • Dudbridge, F.1
  • 9
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNFand human memory and hippocampal function
    • Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A., et al. 2003. The BDNF val66met polymorphism affects activity-dependent secretion of BDNFand human memory and hippocampal function. Cell 112(2):257-269.
    • (2003) Cell , vol.112 , Issue.2 , pp. 257-269
    • Egan, M.F.1    Kojima, M.2    Callicott, J.H.3    Goldberg, T.E.4    Kolachana, B.S.5    Bertolino, A.6
  • 12
    • 0036499241 scopus 로고    scopus 로고
    • Sample size requirements for association studies of gene-gene interaction
    • Gauderman WJ. 2002. Sample size requirements for association studies of gene-gene interaction. Am J Epidemiol 155(5):478-484.
    • (2002) Am J Epidemiol , vol.155 , Issue.5 , pp. 478-484
    • Gauderman, W.J.1
  • 14
    • 80052048908 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor levels in schizophrenia: A systematic review with meta-analysis
    • Green MJ, Matheson SL, Shepherd A, Weickert CS, Carr VJ. 2011. Brain-derived neurotrophic factor levels in schizophrenia: A systematic review with meta-analysis. Mol Psychiatry 16(9):960-972.
    • (2011) Mol Psychiatry , vol.16 , Issue.9 , pp. 960-972
    • Green, M.J.1    Matheson, S.L.2    Shepherd, A.3    Weickert, C.S.4    Carr, V.J.5
  • 15
    • 0142091432 scopus 로고    scopus 로고
    • An association study of a brain-derived neurotrophic factor Val66Met polymorphism and clozapine response of schizophrenic patients
    • Hong CJ, Yu YW, Lin CH, Tsai SJ. 2003. An association study of a brain-derived neurotrophic factor Val66Met polymorphism and clozapine response of schizophrenic patients. Neurosci Lett 349:206-208.
    • (2003) Neurosci Lett , vol.349 , pp. 206-208
    • Hong, C.J.1    Yu, Y.W.2    Lin, C.H.3    Tsai, S.J.4
  • 17
    • 67349151334 scopus 로고    scopus 로고
    • BDNF is not associated with schizophrenia: data from a Japanese population study and meta-analysis
    • Kawashima K, Ikeda M, Kishi T, Kitajima T, Yamanouchi Y, Kinoshita Y., et al. 2009. BDNF is not associated with schizophrenia: data from a Japanese population study and meta-analysis. Schizophr Res 112:72-79.
    • (2009) Schizophr Res , vol.112 , pp. 72-79
    • Kawashima, K.1    Ikeda, M.2    Kishi, T.3    Kitajima, T.4    Yamanouchi, Y.5    Kinoshita, Y.6
  • 18
    • 0023606101 scopus 로고
    • The positive and negative syndrome scale (PANSS) for schizophrenia
    • Kay SR, Fiszbein A, Opler LA. 1987. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 13:261-276.
    • (1987) Schizophr Bull , vol.13 , pp. 261-276
    • Kay, S.R.1    Fiszbein, A.2    Opler, L.A.3
  • 20
    • 0346025505 scopus 로고    scopus 로고
    • Detecting population stratification using a panel of single nucleotide polymorphisms
    • Lee WC. 2003. Detecting population stratification using a panel of single nucleotide polymorphisms. Int J Epidemiol 32:1120.
    • (2003) Int J Epidemiol , vol.32 , pp. 1120
    • Lee, W.C.1
  • 21
    • 64149129354 scopus 로고    scopus 로고
    • Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes
    • Lencz T, Lipsky RH, DeRosse P, Burdick KE, Kane JM, Malhotra AK. 2009. Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypes. Br J Psychiatry 194(4):313-3318.
    • (2009) Br J Psychiatry , vol.194 , Issue.4 , pp. 313-3318
    • Lencz, T.1    Lipsky, R.H.2    DeRosse, P.3    Burdick, K.E.4    Kane, J.M.5    Malhotra, A.K.6
  • 22
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN. 2003. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33(2):177-182.
    • (2003) Nat Genet , vol.33 , Issue.2 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 23
    • 80052501979 scopus 로고    scopus 로고
    • Genetic animal models of schizophrenia related with the hypothesis of abnormal neurodevelopment
    • Lu L, Mamiya T, Koseki T, Mouri A, Nabeshima T. 2011. Genetic animal models of schizophrenia related with the hypothesis of abnormal neurodevelopment. Biol Pharm Bull 34(9):1358-1363.
    • (2011) Biol Pharm Bull , vol.34 , Issue.9 , pp. 1358-1363
    • Lu, L.1    Mamiya, T.2    Koseki, T.3    Mouri, A.4    Nabeshima, T.5
  • 24
    • 55249091422 scopus 로고    scopus 로고
    • Schizophrenia: A concise overview of incidence, prevalence, and mortality
    • McGrath J, Saha S, Chant D, Welham J. 2008. Schizophrenia: A concise overview of incidence, prevalence, and mortality. Epidemiol Rev 30:67-76.
    • (2008) Epidemiol Rev , vol.30 , pp. 67-76
    • McGrath, J.1    Saha, S.2    Chant, D.3    Welham, J.4
  • 26
    • 33947187626 scopus 로고    scopus 로고
    • No association between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and schizophrenia in Asian populations: Evidence from a case-control study and meta-analysis
    • Naoe Y, Shinkai T, Hori H, Fukunaka Y, Utsunomiya K, Sakata S., et al. 2007. No association between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and schizophrenia in Asian populations: Evidence from a case-control study and meta-analysis. Neurosci Lett 415:108-112.
    • (2007) Neurosci Lett , vol.415 , pp. 108-112
    • Naoe, Y.1    Shinkai, T.2    Hori, H.3    Fukunaka, Y.4    Utsunomiya, K.5    Sakata, S.6
  • 27
    • 0033659799 scopus 로고    scopus 로고
    • Cytokine and growth factor involvement in schizophrenia-support for the developmental model
    • Nawa H, Takahashi M, Patterson PH. 2000. Cytokine and growth factor involvement in schizophrenia-support for the developmental model. Mol Psychiatry 5(6):594-603.
    • (2000) Mol Psychiatry , vol.5 , Issue.6 , pp. 594-603
    • Nawa, H.1    Takahashi, M.2    Patterson, P.H.3
  • 30
    • 33646510499 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms
    • Numata S, Ueno S, Iga J, Yamauchi K, Hongwei S, Ohta K., et al. 2006. Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism in schizophrenia is associated with age at onset and symptoms. Neurosci Lett 401:1-5.
    • (2006) Neurosci Lett , vol.401 , pp. 1-5
    • Numata, S.1    Ueno, S.2    Iga, J.3    Yamauchi, K.4    Hongwei, S.5    Ohta, K.6
  • 31
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt DR. 2004. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74(4):765-769.
    • (2004) Am J Hum Genet , vol.74 , Issue.4 , pp. 765-769
    • Nyholt, D.R.1
  • 33
    • 33845984498 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and risk of schizophrenia: An association study and meta-analysis
    • Qian L, Zhao J, Shi Y, Zhao X, Feng G, Xu F, et al. 2007. Brain-derived neurotrophic factor and risk of schizophrenia: An association study and meta-analysis. Biochem Biophys Res Commun 353:738-743.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 738-743
    • Qian, L.1    Zhao, J.2    Shi, Y.3    Zhao, X.4    Feng, G.5    Xu, F.6
  • 36
    • 32244434819 scopus 로고    scopus 로고
    • The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study
    • Rosa A, Cuesta MJ, Fatjo-Vilas M, Peralta V, Zarzuela A, Fananas L. 2006. The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study. Am J Med Genet Part B 141B:135-138.
    • (2006) Am J Med Genet Part B , vol.141 B , pp. 135-138
    • Rosa, A.1    Cuesta, M.J.2    Fatjo-Vilas, M.3    Peralta, V.4    Zarzuela, A.5    Fananas, L.6
  • 37
    • 23644432395 scopus 로고    scopus 로고
    • Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression
    • Schumacher J, Jamra RA, Becker T, Ohlraun S, Klopp N, Binder EB, et al. 2005. Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression. Biol Psychiatry 58(4):307-314.
    • (2005) Biol Psychiatry , vol.58 , Issue.4 , pp. 307-314
    • Schumacher, J.1    Jamra, R.A.2    Becker, T.3    Ohlraun, S.4    Klopp, N.5    Binder, E.B.6
  • 38
    • 84858846969 scopus 로고    scopus 로고
    • Association study between BDNF C-281A polymorphism and paranoid schizophrenia in polish population
    • Suchanek R, Owczarek A, Kowalski J. 2012. Association study between BDNF C-281A polymorphism and paranoid schizophrenia in polish population. J Mol Neurosci 46(1):217-222.
    • (2012) J Mol Neurosci , vol.46 , Issue.1 , pp. 217-222
    • Suchanek, R.1    Owczarek, A.2    Kowalski, J.3
  • 39
    • 19444386373 scopus 로고    scopus 로고
    • Decreased BDNF in serum of patients with chronic schizophrenia on long-term treatment with antipsychotics
    • Tan YL, Zhou DF, Cao LY, Zou YZ, Zhang XY. 2005. Decreased BDNF in serum of patients with chronic schizophrenia on long-term treatment with antipsychotics. Neurosci Lett 382(1-2):27-32.
    • (2005) Neurosci Lett , vol.382 , Issue.1-2 , pp. 27-32
    • Tan, Y.L.1    Zhou, D.F.2    Cao, L.Y.3    Zou, Y.Z.4    Zhang, X.Y.5
  • 40
    • 33747200830 scopus 로고    scopus 로고
    • The PLA2G4A gene and negative symptoms in a Chinese population
    • Tao R, Wei J, Guo Y, Yu Y, Xu Q, Shi J., et al. 2006. The PLA2G4A gene and negative symptoms in a Chinese population. Schizophr Res 86:326-328.
    • (2006) Schizophr Res , vol.86 , pp. 326-328
    • Tao, R.1    Wei, J.2    Guo, Y.3    Yu, Y.4    Xu, Q.5    Shi, J.6
  • 41
    • 68949180394 scopus 로고    scopus 로고
    • Schizophrenia
    • Van Os J, Kapur S. 2009. Schizophrenia. Lancet 374(9690):635-645.
    • (2009) Lancet , vol.374 , Issue.9690 , pp. 635-645
    • Van Os, J.1    Kapur, S.2
  • 42
    • 54249120358 scopus 로고    scopus 로고
    • Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction
    • van Winkel R, Stefanis NC, Myin-Germeys I. 2008. Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction. Schizophr Bull 34:1095-1105.
    • (2008) Schizophr Bull , vol.34 , pp. 1095-1105
    • van Winkel, R.1    Stefanis, N.C.2    Myin-Germeys, I.3
  • 43
    • 77954143925 scopus 로고    scopus 로고
    • The Val66Met polymorphism of the brain-derived neurotrophic factor gene is not associated with risk for schizophrenia and tardive dyskinesia in Han Chinese population
    • Wang Y, Wang JD, Wu HR, Zhang BS, Fang H, Ma QM, et al. 2010. The Val66Met polymorphism of the brain-derived neurotrophic factor gene is not associated with risk for schizophrenia and tardive dyskinesia in Han Chinese population. Schizophr Res 120:240-242.
    • (2010) Schizophr Res , vol.120 , pp. 240-242
    • Wang, Y.1    Wang, J.D.2    Wu, H.R.3    Zhang, B.S.4    Fang, H.5    Ma, Q.M.6
  • 44
    • 33747502544 scopus 로고    scopus 로고
    • No association between the brain-derived neurotrophic factor gene and schizophrenia in a Japanese population
    • Watanabe Y, Muratake T, Kaneko N, Nunokawa A, Someya T. 2006. No association between the brain-derived neurotrophic factor gene and schizophrenia in a Japanese population. Schizophr Res 84(1):29-35.
    • (2006) Schizophr Res , vol.84 , Issue.1 , pp. 29-35
    • Watanabe, Y.1    Muratake, T.2    Kaneko, N.3    Nunokawa, A.4    Someya, T.5
  • 45
    • 34548180031 scopus 로고    scopus 로고
    • Meta-analysis of case-control association studies between the C270T polymorphism of the brain-derived neurotrophic factor gene and schizophrenia
    • Watanabe Y, Nunokawa A, Kaneko N, Someya T. 2007. Meta-analysis of case-control association studies between the C270T polymorphism of the brain-derived neurotrophic factor gene and schizophrenia. Schizophr Res 95(1-3):250-252.
    • (2007) Schizophr Res , vol.95 , Issue.1-3 , pp. 250-252
    • Watanabe, Y.1    Nunokawa, A.2    Kaneko, N.3    Someya, T.4
  • 46
    • 68249117473 scopus 로고    scopus 로고
    • New insights into the role of brain-derived neurotrophic factor in synaptic plasticity
    • Waterhouse EG, Xu B. 2009. New insights into the role of brain-derived neurotrophic factor in synaptic plasticity. Mol Cell Neurosci 42:81-89.
    • (2009) Mol Cell Neurosci , vol.42 , pp. 81-89
    • Waterhouse, E.G.1    Xu, B.2
  • 47
    • 0038266756 scopus 로고    scopus 로고
    • Chlorpromazine equivalent doses for the newer atypical antipsychotics
    • Woods SW. 2003. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry 64(6):663-667.
    • (2003) J Clin Psychiatry , vol.64 , Issue.6 , pp. 663-667
    • Woods, S.W.1
  • 48
    • 33847303530 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene C-270T and Val66Met functional polymorphisms and risk of schizophrenia: a moderate-scale population-based study and meta-analysis
    • Xu MQ, St Clair D, Ott J, Feng GY, He L. 2007. Brain-derived neurotrophic factor gene C-270T and Val66Met functional polymorphisms and risk of schizophrenia: a moderate-scale population-based study and meta-analysis. Schizophr Res 91:6-13.
    • (2007) Schizophr Res , vol.91 , pp. 6-13
    • Xu, M.Q.1    St Clair, D.2    Ott, J.3    Feng, G.Y.4    He, L.5
  • 49
    • 77955125925 scopus 로고    scopus 로고
    • Neither single-marker nor haplotype analyses support an association between the dopamine transporter gene and heroin dependence in Han Chinese
    • Yeh YW, Lu RB, Tao PL, Shih MC, Lin WW, Huang SY. 2010. Neither single-marker nor haplotype analyses support an association between the dopamine transporter gene and heroin dependence in Han Chinese. Genes Brain Behav 9(6):638-647.
    • (2010) Genes Brain Behav , vol.9 , Issue.6 , pp. 638-647
    • Yeh, Y.W.1    Lu, R.B.2    Tao, P.L.3    Shih, M.C.4    Lin, W.W.5    Huang, S.Y.6
  • 51
    • 34548172739 scopus 로고    scopus 로고
    • Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics
    • Zhang XY, Tan YL, Zhou DF, Cao LY, Wu GY, Xu Q, et al. 2007. Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics. J Psychiatr Res 41(12):997-1004.
    • (2007) J Psychiatr Res , vol.41 , Issue.12 , pp. 997-1004
    • Zhang, X.Y.1    Tan, Y.L.2    Zhou, D.F.3    Cao, L.Y.4    Wu, G.Y.5    Xu, Q.6
  • 52
    • 34247101730 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene polymorphisms and schizophrenia: A meta-analysis
    • Zintzaras E. 2007. Brain-derived neurotrophic factor gene polymorphisms and schizophrenia: A meta-analysis. Psychiatr Genet 17:69-75.
    • (2007) Psychiatr Genet , vol.17 , pp. 69-75
    • Zintzaras, E.1


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