Compounds isolated from Psoralea corylifolia seeds inhibit protein kinase activity and induce apoptotic cell death in mammalian cells

Journal of Pharmacy and Pharmacology

Volumn 65, Issue 9, 2013, Pages 1393-1408

  Limper, Christian ^a   Wang, Yao ^a   Ruhl, Sven ^a   Wang, Zhiqiang ^d   Lou, Yijia ^d   Totzke, Frank ^b   Kubbutat, Michael H G ^b   Chovolou, Yvonni ^a   Proksch, Peter ^a   Wätjen, Wim ^a,c  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b PROQINASE GMBH   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

apoptosis; cancer; cytotoxicity; kinase inhibitor; oxidative stress

Indexed keywords

7,2',4' TRIHYDROXY 3 ARYLCOUMARIN; ANTIOXIDANT; BAKUCHALCONE; BAVACHROMENE; CORYLIFOL C; CORYLIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ISOWIGHTEONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PLANT MEDICINAL PRODUCT; PROTEIN KINASE; PSORACHALCONE A; PSORACOUMESTAN; STRESS ACTIVATED PROTEIN KINASE; TROLOX C; UNCLASSIFIED DRUG; WIGHTEONE; XANTHOANGELOL;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; OXIDATIVE STRESS; PLANT SEED; PROTEIN PHOSPHORYLATION; PSORALEA; PSORALEA CORYLIFOLIA; RAT; WESTERN BLOTTING;

EID: 84881478116     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12107     Document Type: Article

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