In vitro protein tyrosine phosphatase 1B inhibitory phenols from the seeds of Psoralea corylifolia

Planta Medica

Volumn 71, Issue 1, 2005, Pages 87-89

  Kim, Youn Chul ^a   Oh, Hyuncheol ^b   Kim, Beom Seok ^b   Kang, Tai Hyun ^a   Ko, Eun Kyoung ^a   Han, Yu Mi ^b   Kim, Bo Yeon ^b   Ahn, Jong Seog ^b  

^a Wonkwang University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BAKUCHIOL; CORYLIN; INSULIN; PHENOL DERIVATIVE; PLANT EXTRACT; PROTEIN TYROSINE PHOSPHATASE 1B; PSORALIDIN; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; DIABETES MELLITUS; DOSE RESPONSE; DRUG STRUCTURE; ENZYME INHIBITION; IC 50; IN VITRO STUDY; INSULIN SENSITIVITY; KINETICS; MICHAELIS CONSTANT; NEGATIVE FEEDBACK; PLANT SEED; PSORALEA; PSORALEA CORYLIFOLIA; REACTION ANALYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; PROTEIN-TYROSINE-PHOSPHATASE; PSORALEA; SEEDS;

EID: 13544251486     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-837759     Document Type: Article

References (16)

1. Moller DE. New drug targets for type 2 diabetes and the metabolic syndrome. Nature 2001; 414: 821-7
2. van Huijsduijnen RH, Bombrun A, Swinnen D. Selecting protein tyrosine phosphatases as drug targets. Drug Discov Today 2002; 7: 1013-9
3. Johnson TO, Ermolieff J, Jirousek MR. Protein tyrosine phosphatase 1B inhibitors for diabetes. Nat Rev Drug Discov 2002; 1: 696-709
4. Huyer G, Liu S, Kelly J, Moffat J, Payette P, Kennedy B, Tsaprailis G, Gresser MJ, Ramachandran C. Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate. J Biol Chem 1997; 272:843-51
5. Goldwaser I, Gefel D, Gershonov E, Fridkin M, Shechter Y. Insulin-like effects of vanadium: basic and clinical implications. J Inorg Biochem 2000;80:21-5
6. Imparl-Radosevich J, Deas S, Polansky MM, Baedke DA, Ingebritsen TS, Anderson RA, Graves DJ. Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling. Horm Res 1998; 50: 177-82
7. Chen RM, Hu LH, An TY, Li J, Shen Q. Natural PTP1B inhibitors from Broussonetia papyrifera. Bioorg Med Chem Lett 2002; 12: 3387-90
8. Zhu YP. Chinese Materia Medica: Chemistry, Pharmacology and Applications. Amsterdam: Harwood Academic Publishers, 1998: pp 609-12
9. Yang YM, Hyun JW, Sung MS, Chung HS, Kim BK, Paik WH, Kang SS, Park JG. The cytotoxicity of psoralidin from Psoralea corylifolia. Planta Med 1996; 62: 353-4
10. Cho H, Jun JY, Song EK, Kang KH, Baek HY, Ko YS, Kim YC. Bakuchiol: a hepatoprotective compound of Psoralea corylifolia on tacrine-induced cytotoxicity in Hep G2 cells. Planta Med 2001; 67: 750-1
11. Wang D, Li F, Jiang Z. Osteoblastic proliferation stimulating activity of Psoralea corylifolia extracts and two of its flavonoids. Planta Med 2001; 67: 748-9
12. Xiong Z, Wang D, Xu Y, Li F. Osteoblastic differentiation bioassay and its application to investigating the activity of fractions and compounds from Psoralea corylifolia L. Pharmazie 2003; 58: 925-8
13. Khatune NA, Islam ME, Haque ME, Khondkar P, Rahman MM. Antibacterial compounds from the seeds of Psoralea corylifolia. Fitoterapia 2004; 75: 228-30
14. 1 phase. FEBS Letters 1995; 372: 54-8
15. Iwamura J, Dohi T, Tanaka H, Odani T, Kubo M. Cytotoxicity of corylifoliae fructus. II. Cytotoxicity of bakuchiol and the analogues. Yakugaku Zasshi 1989; 109: 962-5
16. Lee MS, Oh WK, Kim BY, Ahn SC, Kang DO, Sohn CB, Osada H, Ahn JS. Inhibition of VHR dual-specificity protein tyrosine phosphatase activity by flavonoids isolated from Scutellaria baicalensis: structure-activity relationships. Planta Med 2002; 68: 1063-5