Extracellular cleavage of the p75 neurotrophin receptor is implicated in its pro-survival effect in breast cancer cells

FEBS Letters

Volumn 587, Issue 16, 2013, Pages 2591-2596

  Verbeke, Stéphanie ^a   Tomellini, Elisa ^a   Dhamani, Fatima ^a,b   Meignan, Samuel ^a   Adriaenssens, Eric ^a,b   Xuefen, Le Bourhis ^a  

^a UNIV LILLE   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

Author keywords

Breast cancer cell; p75NTR; Regulated proteolysis; Survival

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTROPHIN RECEPTOR P75; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CARBOXY TERMINAL SEQUENCE; CELL SURVIVAL; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; SIGNAL TRANSDUCTION;

A DISINTEGRIN AND METALLOPROTEASE; ADAM; BREAST CANCER CELL; CARBOXYL-TERMINAL FRAGMENT; CTF; FBS; FETAL BOVINE SERUM; ICD; INTRACELLULAR DOMAIN; P75(NTR); PRESENILIN; PS; REGULATED INTRAMEMBRANE PROTEOLYSIS; REGULATED PROTEOLYSIS; RIP; SURVIVAL; TAPI; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRAIL; TUMOR NECROSIS FACTOR-Α PROTEASE INHIBITOR;

BREAST NEOPLASMS; CASPASE 3; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; POLY(ADP-RIBOSE) POLYMERASES; RECEPTOR, NERVE GROWTH FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84881477565     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.06.039     Document Type: Article

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