Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Pan, Chang ^a,b   Liu, Hong Da ^a   Gong, Zheng ^a,c   Yu, Xiao ^a   Hou, Xu Ben ^a   Xie, Di Dong ^a   Zhu, Xi Bin ^a   Li, Hao Wen ^d   Tang, Jun Yi ^a   Xu, Yun Fei ^a,b   Yu, Jia Qi ^a   Zhang, Lian Ying ^a   Fang, Hao ^a   Xiao, Kun Hong ^e   Chen, Yu Guo ^b   Wang, Jiang Yun ^f   Pang, Qi ^a   Chen, Wei ^d,e   Sun, Jin Peng ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

^d CAPITAL MEDICAL UNIVERSITY   (China)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

^f INSTITUTE OF BIOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN BINDING; PROTEIN PHOSPHATASE 2C; PHOSPHOPROTEIN PHOSPHATASE 2C;

ANTAGONISTS AND INHIBITORS; BINDING SITE; CHEMICAL MODEL; CHEMISTRY; COMPUTER SIMULATION; ENZYME ACTIVATION; HEK293 CELL LINE; HUMAN; KINETICS; METABOLISM; ARTICLE; CELL STRAIN HEK293; DRUG ANTAGONISM; PROTEIN BINDING;

BINDING SITES; CADMIUM; COMPUTER SIMULATION; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; KINETICS; MODELS, CHEMICAL; PHOSPHOPROTEIN PHOSPHATASES; PROTEIN BINDING;

EID: 84881451906     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep02333     Document Type: Article

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