Insights into the importance of DFD-motif and insertion I1 in stabilizing the DFD-out conformation of Mnk2 kinase

ACS Medicinal Chemistry Letters

Volumn 4, Issue 8, 2013, Pages 736-741

  Hou, Jinqiang ^a   Teo, Theodosia ^a   Sykes, Matthew J ^a   Wang, Shudong ^a  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

DFD motif; insertion I1; Mnk; molecular dynamics simulation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE INTERACTING KINASE 2; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; HIGH TEMPERATURE; MOLECULAR DYNAMICS; MUTANT; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; SEQUENCE HOMOLOGY;

EID: 84881451886     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml400145x     Document Type: Article

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