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Volumn 32, Issue 4, 2013, Pages 296-307

Cytotoxicity and genotoxicity of copper oxide nanoparticles in human skin keratinocytes cells

Author keywords

apoptosis; copper oxide nanoparticles; DNA damage; human skin cells; oxidative stress

Indexed keywords

CASPASE 3; CATALASE; COPPER OXIDE NANOPARTICLE; DNA; LIPID; NANOPARTICLE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 84881447859     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581813487563     Document Type: Article
Times cited : (150)

References (45)
  • 2
    • 67349133554 scopus 로고    scopus 로고
    • Nano genotoxicology: The DNA damaging potential of engineered nanomaterials
    • Singh N, Manshian B, Jenkins GJS, et al. Nano genotoxicology: the DNA damaging potential of engineered nanomaterials. Biomaterials. 2009 ; 30 (23-24). 3891-3914
    • (2009) Biomaterials , vol.30 , Issue.2324 , pp. 3891-3914
    • Singh, N.1    Manshian, B.2    Jenkins, G.J.S.3
  • 3
    • 81755171094 scopus 로고    scopus 로고
    • Titanium dioxide in our everyday life; Is it safe?
    • Skocaj M, Filipic M, Petkovic J, Novak S. Titanium dioxide in our everyday life; is it safe?. Radiol Oncol. 2011 ; 45 (4). 227-247
    • (2011) Radiol Oncol , vol.45 , Issue.4 , pp. 227-247
    • Skocaj, M.1    Filipic, M.2    Petkovic, J.3    Novak, S.4
  • 4
    • 79958772996 scopus 로고    scopus 로고
    • Polypropylene with embedded copper metal or copper oxide nanoparticles as a novel plastic antimicrobial agent
    • Delgado K, Quijada R, Palma R, Palza H. Polypropylene with embedded copper metal or copper oxide nanoparticles as a novel plastic antimicrobial agent. Lett Appl Microbiol. 2011 ; 53 (1). 50-54
    • (2011) Lett Appl Microbiol , vol.53 , Issue.1 , pp. 50-54
    • Delgado, K.1    Quijada, R.2    Palma, R.3    Palza, H.4
  • 5
    • 84863951606 scopus 로고    scopus 로고
    • CuO nanoparticle interaction with human epithelial cells: Cellular uptake, location, export, and genotoxicity
    • Wang Z, Li N, Zhao J, White JC, Qu O, Xing B. CuO nanoparticle interaction with human epithelial cells: cellular uptake, location, export, and genotoxicity. Chem Res Toxicol. 2012 ; 25 (7). 1512-1521
    • (2012) Chem Res Toxicol , vol.25 , Issue.7 , pp. 1512-1521
    • Wang, Z.1    Li, N.2    Zhao, J.3    White, J.C.4    Qu, O.5    Xing, B.6
  • 6
    • 80155201448 scopus 로고    scopus 로고
    • Fate and toxicity of metallic and metal-containing nanoparticles for biomedical applications
    • Li Y-F, Chen C. Fate and toxicity of metallic and metal-containing nanoparticles for biomedical applications. Small. 2011 ; 7 (21). 2965-2980
    • (2011) Small , vol.7 , Issue.21 , pp. 2965-2980
    • Li, Y.-F.1    Chen, C.2
  • 7
    • 40949113637 scopus 로고    scopus 로고
    • Toxicity of nano sized and bulk ZnO, CuO and TiO2 to bacteria Vibrio fischeri, crustaceans Daphnia magna and Thamnocephalus platyurus
    • Heinlaan M, Ivask A, Blinova I, Dubourguier HC, Kahru A.. Toxicity of nano sized and bulk ZnO, CuO and TiO2 to bacteria Vibrio fischeri, crustaceans Daphnia magna and Thamnocephalus platyurus. Chemosphere. 2008 ; 71 (7). 1308-1316
    • (2008) Chemosphere , vol.71 , Issue.7 , pp. 1308-1316
    • Heinlaan, M.1    Ivask, A.2    Blinova, I.3    Dubourguier, H.C.4    Kahru, A.5
  • 8
    • 71549142045 scopus 로고    scopus 로고
    • Selective cytotoxic effect of ZnO nanoparticles on glioma cells
    • Ostrovsky S, Kazimirsky G, Gedanken A, Brodie C. Selective cytotoxic effect of ZnO nanoparticles on glioma cells. Nano Res. 2009 ; 2 (11). 882-890
    • (2009) Nano Res , vol.2 , Issue.11 , pp. 882-890
    • Ostrovsky, S.1    Kazimirsky, G.2    Gedanken, A.3    Brodie, C.4
  • 9
    • 53549086404 scopus 로고    scopus 로고
    • Copper oxide nanoparticles are highly toxic: A comparison between metal oxide nanoparticles and carbon nanotubes
    • Karlsson HL, Cronholm P, Gustafsson J, Moller L. Copper oxide nanoparticles are highly toxic: a comparison between metal oxide nanoparticles and carbon nanotubes. Chem Res Toxicol. 2008 ; 21 (9). 1726-1732
    • (2008) Chem Res Toxicol , vol.21 , Issue.9 , pp. 1726-1732
    • Karlsson, H.L.1    Cronholm, P.2    Gustafsson, J.3    Moller, L.4
  • 10
    • 37549005552 scopus 로고    scopus 로고
    • High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles
    • Li F, Zhou X, Zhu J, Ma J, Huang X, Wong STC. High content image analysis for human H4 neuroglioma cells exposed to CuO nanoparticles. BMC Biotechnol. 2007 ; 7: 66
    • (2007) BMC Biotechnol , vol.7 , pp. 66
    • Li, F.1    Zhou, X.2    Zhu, J.3    Ma, J.4    Huang, X.5    Wong, S.T.C.6
  • 11
    • 65449128102 scopus 로고    scopus 로고
    • Differential cytotoxicity of metal oxide nanoparticles
    • Chen J, Zhu J, Cho HH, et al. Differential cytotoxicity of metal oxide nanoparticles. J Exp Nanosci. 2008 ; 3 (4). 321-328
    • (2008) J Exp Nanosci , vol.3 , Issue.4 , pp. 321-328
    • Chen, J.1    Zhu, J.2    Cho, H.H.3
  • 12
    • 78649361273 scopus 로고    scopus 로고
    • Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats
    • Sharma HS, Hussain S, Schlager J, Ali SF, Sharma A. Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats. Acta Neurochir Suppl. 2010 ; 106: 359-364
    • (2010) Acta Neurochir Suppl , vol.106 , pp. 359-364
    • Sharma, H.S.1    Hussain, S.2    Schlager, J.3    Ali, S.F.4    Sharma, A.5
  • 13
    • 45849128316 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes
    • Kang SJ, Kim BM, Lee YJ, Chung H. Titanium dioxide nanoparticles trigger p53-mediated damage response in peripheral blood lymphocytes. Environ Mol Mutagen. 2008 ; 49 (5). 399-405
    • (2008) Environ Mol Mutagen , vol.49 , Issue.5 , pp. 399-405
    • Kang, S.J.1    Kim, B.M.2    Lee, Y.J.3    Chung, H.4
  • 14
    • 38149135806 scopus 로고    scopus 로고
    • Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique
    • Murdock RC, Braydich-Stolle L, Schrand AM, Schlager JJ, Hussain SM. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicol Sci. 2007 ; 101 (2). 239-253
    • (2007) Toxicol Sci , vol.101 , Issue.2 , pp. 239-253
    • Murdock, R.C.1    Braydich-Stolle, L.2    Schrand, A.M.3    Schlager, J.J.4    Hussain, S.M.5
  • 15
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mossman T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983 ; 65 (1-2). 55-63
    • (1983) J Immunol Methods , vol.65 , Issue.12 , pp. 55-63
    • Mossman, T.1
  • 16
    • 12244254598 scopus 로고
    • Lactate dehydrogenase activity in blood
    • Wroblewski F, LaDue JS. Lactate dehydrogenase activity in blood. Proc Soc Exp Biol Med. 1955 ; 90 (1). 210-213
    • (1955) Proc Soc Exp Biol Med , vol.90 , Issue.1 , pp. 210-213
    • Wroblewski, F.1    Ladue, J.S.2
  • 17
    • 0032820452 scopus 로고    scopus 로고
    • Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
    • Wang H, Joseph JA. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic Biol Med. 1999 ; 27 (5-6). 612-616
    • (1999) Free Radic Biol Med , vol.27 , Issue.56 , pp. 612-616
    • Wang, H.1    Joseph, J.A.2
  • 18
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976 ; 72: 248-254
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 19
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979 ; 95 (2). 351-358
    • (1979) Anal Biochem , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 20
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman G. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959 ; 82 (1). 70-77
    • (1959) Arch Biochem Biophys , vol.82 , Issue.1 , pp. 70-77
    • Ellman, G.1
  • 21
    • 0021681627 scopus 로고
    • A modified spectrophotometric assay of superoxide dismutase
    • Kakkar PS, Das B, Viswanathan PN. A modified spectrophotometric assay of superoxide dismutase. Ind. J Biochem Biophys. 1984 ; 21 (2). 130-132
    • (1984) Ind. J Biochem Biophys , vol.21 , Issue.2 , pp. 130-132
    • Kakkar, P.S.1    Das, B.2    Viswanathan, P.N.3
  • 22
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • Sinha AK. Colorimetric assay of catalase. Anal Biochem. 1972 ; 47 (2). 389-394
    • (1972) Anal Biochem , vol.47 , Issue.2 , pp. 389-394
    • Sinha, A.K.1
  • 23
    • 36649019376 scopus 로고    scopus 로고
    • AICAR inhibits proliferation and induced s-phase arrest and promotes apoptosis in CaSki cells
    • Guan T, Qin F, Du J, Geng L, Zhang Y, Li M. AICAR inhibits proliferation and induced s-phase arrest and promotes apoptosis in CaSki cells. Acta Pharmacol Sin. 2007 ; 28 (12). 1984-1990
    • (2007) Acta Pharmacol Sin , vol.28 , Issue.12 , pp. 1984-1990
    • Guan, T.1    Qin, F.2    Du, J.3    Geng, L.4    Zhang, Y.5    Li, M.6
  • 24
    • 0023919963 scopus 로고
    • A simple technique for quantization of low levels of DNA damage in individual cells
    • Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantization of low levels of DNA damage in individual cells. Exp Cell Res. 1988 ; 175 (1). 184-191
    • (1988) Exp Cell Res , vol.175 , Issue.1 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 25
    • 77957948549 scopus 로고    scopus 로고
    • UVA-induced cyototoxicity and DNA damaging potential of Benz (e) acephenanthrylene in human skin cell line
    • Ali D, Ray RS, Hans RK. UVA-induced cyototoxicity and DNA damaging potential of Benz (e) acephenanthrylene in human skin cell line. Toxicol Lett. 2010 ; 199 (2). 193-200
    • (2010) Toxicol Lett , vol.199 , Issue.2 , pp. 193-200
    • Ali, D.1    Ray, R.S.2    Hans, R.K.3
  • 26
    • 0028305534 scopus 로고
    • The effect of various antioxidants and other modifying agents on oxygen-radical generated DNA damage inhuman lymphocytes in the comet assay
    • Anderson D, Yu TW, Phillips BJ, Schmerzer P. The effect of various antioxidants and other modifying agents on oxygen-radical generated DNA damage inhuman lymphocytes in the comet assay. Mutat Res. 1994 ; 307 (1). 261-271
    • (1994) Mutat Res , vol.307 , Issue.1 , pp. 261-271
    • Anderson, D.1    Yu, T.W.2    Phillips, B.J.3    Schmerzer, P.4
  • 27
    • 67651213676 scopus 로고    scopus 로고
    • Nanomaterials: A challenge for toxicologists
    • Dhawan A, Sharma V, Parmar D. Nanomaterials: a challenge for toxicologists. Nanotoxicology. 2009 ; 3 (1). 1-9
    • (2009) Nanotoxicology , vol.3 , Issue.1 , pp. 1-9
    • Dhawan, A.1    Sharma, V.2    Parmar, D.3
  • 28
    • 58149267870 scopus 로고    scopus 로고
    • Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line
    • Monteiro-Riviere NA, Inman AO, Zhang LW. Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line. Toxicol Appl Pharmacol. 2009 ; 234 (2). 222-235
    • (2009) Toxicol Appl Pharmacol , vol.234 , Issue.2 , pp. 222-235
    • Monteiro-Riviere, N.A.1    Inman, A.O.2    Zhang, L.W.3
  • 29
    • 84866125214 scopus 로고    scopus 로고
    • Evaluation of topically applied copper (II) oxide nanoparticle cytotoxicity in human skin organ culture
    • Cohen D, Soroka Y, Maor Z, et al. Evaluation of topically applied copper (II) oxide nanoparticle cytotoxicity in human skin organ culture. Toxicol In Vitro. 2013 ; 27 (1). 292-298
    • (2013) Toxicol in Vitro , vol.27 , Issue.1 , pp. 292-298
    • Cohen, D.1    Soroka, Y.2    Maor, Z.3
  • 30
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nano-level
    • Nel A, Xia T, Madler L, Li N. Toxic potential of materials at the nano-level. Science. 2006 ; 311 (5761). 622-627
    • (2006) Science , vol.311 , Issue.5761 , pp. 622-627
    • Nel, A.1    Xia, T.2    Madler, L.3    Li, N.4
  • 31
    • 33748310797 scopus 로고    scopus 로고
    • Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm
    • Xia T, Kovochich M, Brant J, et al. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett. 2006 ; 6 (8). 1794-1807
    • (2006) Nano Lett , vol.6 , Issue.8 , pp. 1794-1807
    • Xia, T.1    Kovochich, M.2    Brant, J.3
  • 32
    • 34247490186 scopus 로고    scopus 로고
    • Mitochondria, oxidative stress and cell death
    • Ott M, Gogvadze V, Orrenius S, Zhivotovsky B. Mitochondria, oxidative stress and cell death. Apoptosis. 2007 ; 12 (5). 913-922
    • (2007) Apoptosis , vol.12 , Issue.5 , pp. 913-922
    • Ott, M.1    Gogvadze, V.2    Orrenius, S.3    Zhivotovsky, B.4
  • 33
    • 55649109613 scopus 로고    scopus 로고
    • Metals and apoptosis: Recent developments
    • Rana SV. Metals and apoptosis: recent developments. J Trace Elem Med Biol. 2008 ; 22 (4). 262-284
    • (2008) J Trace Elem Med Biol , vol.22 , Issue.4 , pp. 262-284
    • Rana, S.V.1
  • 34
    • 53549086404 scopus 로고    scopus 로고
    • Copper oxide nanoparticles are highly toxic: A comparison between metal oxide nanoparticles and carbon nanotubes
    • Karlsson HL, Cronholm P, Gustafsson J, Moller L. Copper oxide nanoparticles are highly toxic: a comparison between metal oxide nanoparticles and carbon nanotubes. Chem Res Toxicol. 2008 ; 21 (9). 1726-1732
    • (2008) Chem Res Toxicol , vol.21 , Issue.9 , pp. 1726-1732
    • Karlsson, H.L.1    Cronholm, P.2    Gustafsson, J.3    Moller, L.4
  • 35
    • 78650509723 scopus 로고    scopus 로고
    • Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles
    • Song W, Zhang J, Guo J, Ding F, Li L, Sun Z. Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles. Toxicol Lett. 2009 ; 199 (3). 389-397
    • (2009) Toxicol Lett , vol.199 , Issue.3 , pp. 389-397
    • Song, W.1    Zhang, J.2    Guo, J.3    Ding, F.4    Li, L.5    Sun, Z.6
  • 36
    • 67650457630 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles induce apoptosis through the JNK/p38-caspase-8-Bid pathway in phytohemagglutin in-stimulated human lymphocytes
    • Kang SJ, Kim BM, Lee YJ, Hong SH, Chung HW. Titanium dioxide nanoparticles induce apoptosis through the JNK/p38-caspase-8-Bid pathway in phytohemagglutin in-stimulated human lymphocytes. Biochem Biophys Res Commun. 2009 ; 386 (4). 682-687
    • (2009) Biochem Biophys Res Commun , vol.386 , Issue.4 , pp. 682-687
    • Kang, S.J.1    Kim, B.M.2    Lee, Y.J.3    Hong, S.H.4    Chung, H.W.5
  • 37
    • 63249096865 scopus 로고    scopus 로고
    • Oxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, BEAS-2B
    • Eom HJ, Choi J.. Oxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, BEAS-2B. Toxicol Lett. 2009 ; 187 (2). 77-83
    • (2009) Toxicol Lett , vol.187 , Issue.2 , pp. 77-83
    • Eom, H.J.1    Choi, J.2
  • 38
    • 60849117522 scopus 로고    scopus 로고
    • Surface characteristics, copper release, and toxicity of nano-and micrometer-sized copper and copper (II) oxide particles: A cross-disciplinary study
    • Midander K, Cronholm P, Karlsson HL, et al. Surface characteristics, copper release, and toxicity of nano-and micrometer-sized copper and copper (II) oxide particles: a cross-disciplinary study. Small. 2009 ; 5 (3). 389-399
    • (2009) Small , vol.5 , Issue.3 , pp. 389-399
    • Midander, K.1    Cronholm, P.2    Karlsson, H.L.3
  • 39
    • 70349399043 scopus 로고    scopus 로고
    • Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells
    • Fahmy B, Cormier SA. Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells. Toxicol In Vitro. 2009 ; 23 (7). 1365-1371
    • (2009) Toxicol in Vitro , vol.23 , Issue.7 , pp. 1365-1371
    • Fahmy, B.1    Cormier, S.A.2
  • 40
    • 36849054525 scopus 로고    scopus 로고
    • Exposure to copper nanoparticles causes gill injury and acute lethality in zebra fish (Danio rerio)
    • Griffitt RJ, Weil R, Hyndman KA, et al. Exposure to copper nanoparticles causes gill injury and acute lethality in zebra fish (Danio rerio). Environ Sci Technol. 2007 ; 41 (23). 8178-8186
    • (2007) Environ Sci Technol , vol.41 , Issue.23 , pp. 8178-8186
    • Griffitt, R.J.1    Weil, R.2    Hyndman, K.A.3
  • 41
    • 15044357362 scopus 로고    scopus 로고
    • Formation of nucleoplasmic protein aggregates impairs nuclear function in response to SiO2 nanoparticles
    • Chen M, Mikecz A. Formation of nucleoplasmic protein aggregates impairs nuclear function in response to SiO2 nanoparticles. Exp Cell Res. 2005 ; 305 (1). 51-62
    • (2005) Exp Cell Res , vol.305 , Issue.1 , pp. 51-62
    • Chen, M.1    Mikecz, A.2
  • 42
    • 78650519473 scopus 로고    scopus 로고
    • ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells
    • Shukla RK, Sharma V, Pandey AK, Singh S, Sultana S, Dhawan A. ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells. Toxicol In Vitro. 2010 ; 25 (1). 231-241
    • (2010) Toxicol in Vitro , vol.25 , Issue.1 , pp. 231-241
    • Shukla, R.K.1    Sharma, V.2    Pandey, A.K.3    Singh, S.4    Sultana, S.5    Dhawan, A.6
  • 43
    • 8544283254 scopus 로고    scopus 로고
    • The comet assay for DNA damage and repair: Principles, applications, and limitations
    • Collins AR. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol. 2004 ; 26 (3). 249-261
    • (2004) Mol Biotechnol , vol.26 , Issue.3 , pp. 249-261
    • Collins, A.R.1
  • 44
    • 67349174323 scopus 로고    scopus 로고
    • The effect of zinc oxide and titanium dioxide nanoparticles in the Comet assay with UVA photo activation of human sperm and lymphocytes
    • Gopalan RC, Osman IF, Amani A, De Matas M, Anderson D. The effect of zinc oxide and titanium dioxide nanoparticles in the Comet assay with UVA photo activation of human sperm and lymphocytes. Nanotoxicology. 2009 ; 3 (1). 33-39
    • (2009) Nanotoxicology , vol.3 , Issue.1 , pp. 33-39
    • Gopalan, R.C.1    Osman, I.F.2    Amani, A.3    De Matas, M.4    Anderson, D.5
  • 45
    • 10744231806 scopus 로고    scopus 로고
    • Oxidative and alkylating damage in DNA
    • Martinez GR, Loureiro AP, Marques SA, et al. Oxidative and alkylating damage in DNA. Mutat Res. 2003 ; 544 (2-3). 115-127
    • (2003) Mutat Res , vol.544 , Issue.23 , pp. 115-127
    • Martinez, G.R.1    Loureiro, A.P.2    Marques, S.A.3


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