-
1
-
-
78649429727
-
Reduced mortality after allogeneic hematopoietic-cell transplantation
-
Gooley TA, Chien JW, Pergam SA, Hingorani S, Sorror ML, Boeckh M, et al. Reduced mortality after allogeneic hematopoietic-cell transplantation. N Engl J Med 2010;363:2091-101.
-
(2010)
N Engl J Med
, vol.363
, pp. 2091-2101
-
-
Gooley, T.A.1
Chien, J.W.2
Pergam, S.A.3
Hingorani, S.4
Sorror, M.L.5
Boeckh, M.6
-
2
-
-
77649181500
-
Allogeneic haematopoietic stem cell transplantation: Individualized stem cell and immune therapy of cancer
-
Jenq RR, van den Brink MR. Allogeneic haematopoietic stem cell transplantation: individualized stem cell and immune therapy of cancer. Nat Rev Cancer 2010;10:213-21.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 213-221
-
-
Jenq, R.R.1
Van Den Brink, M.R.2
-
3
-
-
70449494642
-
Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease
-
Yi T, Chen Y, Wang L, Du G, Huang D, Zhao D, et al. Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood 2009;114: 3101-12.
-
(2009)
Blood
, vol.114
, pp. 3101-3112
-
-
Yi, T.1
Chen, Y.2
Wang, L.3
Du, G.4
Huang, D.5
Zhao, D.6
-
4
-
-
59649098784
-
IL- 17 contributes to CD4-mediated graft-versus-host disease
-
Kappel LW, Goldberg GL, King CG, Suh DY, Smith OM, Ligh C, et al. IL- 17 contributes to CD4-mediated graft-versus-host disease. Blood 2009;113:945-52.
-
(2009)
Blood
, vol.113
, pp. 945-952
-
-
Kappel, L.W.1
Goldberg, G.L.2
King, C.G.3
Suh, D.Y.4
Smith, O.M.5
Ligh, C.6
-
5
-
-
79960533396
-
Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL
-
Hanash AM, Kappel LW, Yim NL, Nejat RA, Goldberg GL, Smith OM, et al. Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL. Blood 2011;118:446-55.
-
(2011)
Blood
, vol.118
, pp. 446-455
-
-
Hanash, A.M.1
Kappel, L.W.2
Yim, N.L.3
Nejat, R.A.4
Goldberg, G.L.5
Smith, O.M.6
-
6
-
-
75149118145
-
T helper17 cells are sufficient but not necessary to induce acute graftversus- host disease
-
Iclozan C, Yu Y, Liu C, Liang Y, Yi T, Anasetti C, et al. T helper17 cells are sufficient but not necessary to induce acute graftversus- host disease. Biol Blood Marrow Transplant 2010;16: 170-8.
-
(2010)
Biol Blood Marrow Transplant
, vol.16
, pp. 170-178
-
-
Iclozan, C.1
Yu, Y.2
Liu, C.3
Liang, Y.4
Yi, T.5
Anasetti, C.6
-
7
-
-
50049084627
-
The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions
-
Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, et al. The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nat Immunol 2008;9:1055-64.
-
(2008)
Nat Immunol
, vol.9
, pp. 1055-1064
-
-
Kovalovsky, D.1
Uche, O.U.2
Eladad, S.3
Hobbs, R.M.4
Yi, W.5
Alonzo, E.6
-
8
-
-
51349121407
-
The transcription factor PLZF directs the effector program of the NKT cell lineage
-
Savage AK, Constantinides MG, Han J, Picard D, Martin E, Li B, et al. The transcription factor PLZF directs the effector program of the NKT cell lineage. Immunity 2008;29:391-403.
-
(2008)
Immunity
, vol.29
, pp. 391-403
-
-
Savage, A.K.1
Constantinides, M.G.2
Han, J.3
Picard, D.4
Martin, E.5
Li, B.6
-
9
-
-
56649091331
-
The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells
-
Raberger J, Schebesta A, Sakaguchi S, Boucheron N, Blomberg KE, Berglof A, et al. The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells. Proc Natl Acad Sci U S A 2008;105:17919-24.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17919-17924
-
-
Raberger, J.1
Schebesta, A.2
Sakaguchi, S.3
Boucheron, N.4
Blomberg, K.E.5
Berglof, A.6
-
10
-
-
77953627623
-
PLZF induces the spontaneous acquisition of memory/ effector functions in T cells independently of NKT cell-related signals
-
Kovalovsky D, Alonzo ES, Uche OU, Eidson M, Nichols KE, Sant'Angelo DB. PLZF induces the spontaneous acquisition of memory/ effector functions in T cells independently of NKT cell-related signals. J Immunol 2010;184:6746-55.
-
(2010)
J Immunol
, vol.184
, pp. 6746-6755
-
-
Kovalovsky, D.1
Alonzo, E.S.2
Uche, O.U.3
Eidson, M.4
Nichols, K.E.5
Sant'Angelo, D.B.6
-
11
-
-
27644442438
-
CCR2 is required for CD8-induced graft-versus-host disease
-
Terwey TH, Kim TD, Kochman AA, Hubbard VM, Lu S, Zakrzewski JL, et al. CCR2 is required for CD8-induced graft-versus-host disease. Blood 2005;106:3322-30.
-
(2005)
Blood
, vol.106
, pp. 3322-3330
-
-
Terwey, T.H.1
Kim, T.D.2
Kochman, A.A.3
Hubbard, V.M.4
Lu, S.5
Zakrzewski, J.L.6
-
12
-
-
32644449066
-
Absence of beta7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine
-
Waldman E, Lu SX, Hubbard VM, Kochman AA, Eng JM, Terwey TH, et al. Absence of beta7 integrin results in less graft-versus-host disease because of decreased homing of alloreactive T cells to intestine. Blood 2006;107:1703-11.
-
(2006)
Blood
, vol.107
, pp. 1703-1711
-
-
Waldman, E.1
Lu, S.X.2
Hubbard, V.M.3
Kochman, A.A.4
Eng, J.M.5
Terwey, T.H.6
-
13
-
-
58149401207
-
STAT-3 and ERK 1/2 phosphorylation are critical for Tcell alloactivation and graft-versus-host disease
-
Lu SX, Alpdogan O, Lin J, Balderas R, Campos-Gonzalez R, Wang X, et al. STAT-3 and ERK 1/2 phosphorylation are critical for Tcell alloactivation and graft-versus-host disease. Blood 2008;112: 5254-8.
-
(2008)
Blood
, vol.112
, pp. 5254-5258
-
-
Lu, S.X.1
Alpdogan, O.2
Lin, J.3
Balderas, R.4
Campos-Gonzalez, R.5
Wang, X.6
-
14
-
-
77956402670
-
Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease
-
Lu SX, Holland AM, Na IK, Terwey TH, Alpdogan O, Bautista JL, et al. Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease. J Immunol 2010;185:1912-9.
-
(2010)
J Immunol
, vol.185
, pp. 1912-1919
-
-
Lu, S.X.1
Holland, A.M.2
Na, I.K.3
Terwey, T.H.4
Alpdogan, O.5
Bautista, J.L.6
-
15
-
-
44949150198
-
Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion
-
Ghosh A, Wolenski M, Klein C, Welte K, Blazar BR, Sauer MG. Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion. J Immunother 2008;31:121-31.
-
(2008)
J Immunother
, vol.31
, pp. 121-131
-
-
Ghosh, A.1
Wolenski, M.2
Klein, C.3
Welte, K.4
Blazar, B.R.5
Sauer, M.G.6
-
16
-
-
66149112470
-
Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras
-
Ghosh A, Koestner W, Hapke M, Schlaphoff V, Langer F, Baumann R, et al. Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras. Blood 2009;113:4440-8.
-
(2009)
Blood
, vol.113
, pp. 4440-4448
-
-
Ghosh, A.1
Koestner, W.2
Hapke, M.3
Schlaphoff, V.4
Langer, F.5
Baumann, R.6
-
17
-
-
78650653253
-
Interleukin-1 drives cerebrovascular inflammation via MAP kinase-independent pathways
-
Thornton P, McColl BW,Cooper L, Rothwell NJ, Allan SM. Interleukin-1 drives cerebrovascular inflammation via MAP kinase-independent pathways. Curr Neurovasc Res 2010;7:330-40.
-
(2010)
Curr Neurovasc Res
, vol.7
, pp. 330-340
-
-
Thornton, P.1
McColl, B.W.2
Cooper, L.3
Rothwell, N.J.4
Allan, S.M.5
-
18
-
-
80052432708
-
Altered development of NKT cells, gammadelta T cells, CD8 T cells and NK cells in a PLZF deficient patient
-
Eidson M, Wahlstrom J, Beaulieu AM, Zaidi B, Carsons SE, Crow PK, et al. Altered development of NKT cells, gammadelta T cells, CD8 T cells and NK cells in a PLZF deficient patient. PLoS One 2011;6: e24441.
-
(2011)
PLoS One
, vol.6
-
-
Eidson, M.1
Wahlstrom, J.2
Beaulieu, A.M.3
Zaidi, B.4
Carsons, S.E.5
Crow, P.K.6
-
19
-
-
79956194247
-
Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling
-
Savage AK, Constantinides MG, Bendelac A. Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling. J Immunol 2011;186:5801-6.
-
(2011)
J Immunol
, vol.186
, pp. 5801-5806
-
-
Savage, A.K.1
Constantinides, M.G.2
Bendelac, A.3
-
20
-
-
80052173275
-
A repertoire-independent and cell-intrinsic defect in murine GVHD induction by effector memory T cells
-
Juchem KW, Anderson BE, Zhang C, McNiff JM, Demetris AJ, Farber DL, et al. A repertoire-independent and cell-intrinsic defect in murine GVHD induction by effector memory T cells. Blood 2011;118:6209-19.
-
(2011)
Blood
, vol.118
, pp. 6209-6219
-
-
Juchem, K.W.1
Anderson, B.E.2
Zhang, C.3
McNiff, J.M.4
Demetris, A.J.5
Farber, D.L.6
-
21
-
-
79953074487
-
Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4-dependent mechanism
-
Leveson-Gower DB, Olson JA, Sega EI, Luong RH, Baker J, Zeiser R, et al. Low doses of natural killer T cells provide protection from acute graft-versus-host disease via an IL-4-dependent mechanism. Blood 2011;117:3220-9.
-
(2011)
Blood
, vol.117
, pp. 3220-3229
-
-
Leveson-Gower, D.B.1
Olson, J.A.2
Sega, E.I.3
Luong, R.H.4
Baker, J.5
Zeiser, R.6
-
22
-
-
84860652954
-
Graft invariant natural killer T-cell dose predicts risk of acute graftversus- host disease in allogeneic hematopoietic stem cell transplantation
-
Chaidos A, Patterson S, Szydlo R, Chaudhry MS, Dazzi F, Kanfer E, et al.Graft invariant natural killer T-cell dose predicts risk of acute graftversus- host disease in allogeneic hematopoietic stem cell transplantation. Blood 2012;119:5030-6.
-
(2012)
Blood
, vol.119
, pp. 5030-5036
-
-
Chaidos, A.1
Patterson, S.2
Szydlo, R.3
Chaudhry, M.S.4
Dazzi, F.5
Kanfer, E.6
-
23
-
-
79958273555
-
PLZF induces an intravascular surveillance program mediated by long-lived LFA-1-ICAM-1 interactions
-
Thomas SY, Scanlon ST, Griewank KG, Constantinides MG, Savage AK, Barr KA, et al. PLZF induces an intravascular surveillance program mediated by long-lived LFA-1-ICAM-1 interactions. J Exp Med 2011; 208:1179-88.
-
(2011)
J Exp Med
, vol.208
, pp. 1179-1188
-
-
Thomas, S.Y.1
Scanlon, S.T.2
Griewank, K.G.3
Constantinides, M.G.4
Savage, A.K.5
Barr, K.A.6
-
24
-
-
80855128779
-
Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORgammat in mice
-
Yu Y, Wang D, Liu C, Kaosaard K, Semple K, Anasetti C, et al. Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORgammat in mice. Blood 2011;118:5011-20.
-
(2011)
Blood
, vol.118
, pp. 5011-5020
-
-
Yu, Y.1
Wang, D.2
Liu, C.3
Kaosaard, K.4
Semple, K.5
Anasetti, C.6
-
25
-
-
0032100478
-
Differential effects of anti-Fas ligand and anti-tumor necrosis factor alpha antibodies on acute graft-versus-host disease pathologies
-
Hattori K, Hirano T, Miyajima H, Yamakawa N, Tateno M, Oshimi K, et al. Differential effects of anti-Fas ligand and anti-tumor necrosis factor alpha antibodies on acute graft-versus-host disease pathologies. Blood 1998;91:4051-5.
-
(1998)
Blood
, vol.91
, pp. 4051-4055
-
-
Hattori, K.1
Hirano, T.2
Miyajima, H.3
Yamakawa, N.4
Tateno, M.5
Oshimi, K.6
-
26
-
-
0033980662
-
Fas-deficient lpr mice are more susceptible to graftversus- host disease
-
van Den Brink MR, Moore E, Horndasch KJ, Crawford JM, Hoffman J, Murphy GF, et al. Fas-deficient lpr mice are more susceptible to graftversus- host disease. J Immunol 2000;164:469-80.
-
(2000)
J Immunol
, vol.164
, pp. 469-480
-
-
Van Den Brink, M.R.1
Moore, E.2
Horndasch, K.J.3
Crawford, J.M.4
Hoffman, J.5
Murphy, G.F.6
-
27
-
-
0141461418
-
CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
-
Edinger M, Hoffmann P, Ermann J, Drago K, Fathman CG, Strober S, et al. CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med 2003;9:1144-50.
-
(2003)
Nat Med
, vol.9
, pp. 1144-1150
-
-
Edinger, M.1
Hoffmann, P.2
Ermann, J.3
Drago, K.4
Fathman, C.G.5
Strober, S.6
-
28
-
-
79959958408
-
Absence of Stat1 in donor CD4 T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice
-
Ma H, Lu C, Ziegler J, Liu A, Sepulveda A, Okada H, et al. Absence of Stat1 in donor CD4 T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice. J Clin Invest 2011;121: 2554-69.
-
(2011)
J Clin Invest
, vol.121
, pp. 2554-2569
-
-
Ma, H.1
Lu, C.2
Ziegler, J.3
Liu, A.4
Sepulveda, A.5
Okada, H.6
|