Cytotoxic T cells reactive to an immunodominant leukemia-associated antigen can be specifically primed and expanded by combining a specific priming step with nonspecific large-scale expansion

Journal of Immunotherapy

Volumn 31, Issue 2, 2008, Pages 121-131

  Ghosh, Arnab ^a   Wolenski, Matthias ^a   Klein, Christoph ^a   Welte, Karl ^a   Blazar, Bruce R ^b,c   Sauer, Martin G ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Divisions of Pediatric Hematology   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Adoptive immunotherapy; CTL; Dendritic cells; Expander beads; Immunization; Leukemia; Mouse

Indexed keywords

CD8 ANTIGEN; GREEN FLUORESCENT PROTEIN; HERMES ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; LEUKEMIA ANTIGEN; OVALBUMIN; T LYMPHOCYTE RECEPTOR; CD28 ANTIGEN; CD3 ANTIGEN; EGG PROTEIN; EPITOPE; INTERLEUKIN DERIVATIVE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; OVA 8; OVA-8; THYMUS LEUKEMIA ANTIGENS; THYMUS-LEUKEMIA ANTIGENS;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN SPECIFICITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL LYSATE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; ADOPTIVE IMMUNOTHERAPY; ANIMAL; C57BL MOUSE; CHEMISTRY; CYTOLOGY; CYTOTOXICITY; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; KAPLAN MEIER METHOD; LYMPHOCYTE ACTIVATION; METHODOLOGY; PATHOLOGY; SPLEEN; TRANSGENIC MOUSE; TRANSPLANTATION; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD28; ANTIGENS, CD3; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; EGG PROTEINS; IMMUNODOMINANT EPITOPES; IMMUNOTHERAPY, ADOPTIVE; INTERLEUKINS; KAPLAN-MEIERS ESTIMATE; LEUKEMIA; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OVALBUMIN; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SPLEEN; T-LYMPHOCYTES, CYTOTOXIC; TRANSFECTION;

EID: 44949150198     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/CJI.0b013e31815aaf24     Document Type: Article

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