Morphometric analysis of vascular pathology in the orbitofrontal cortex of older subjects with major depression

International Journal of Geriatric Psychiatry

Volumn 28, Issue 9, 2013, Pages 959-970

  Miguel Hidalgo, Jose Javier ^a   Jiang, Wei ^b   Konick, Lisa ^c   Overholser, James C ^c   Jurjus, George J ^c,d   Stockmeier, Craig A ^a,c   Steffens, David C ^b   Krishnan, K Ranga R ^b   Rajkowska, Grazyna ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

blood vessels; depression; morphometry; prefrontal cortex

Indexed keywords

VON WILLEBRAND FACTOR;

ADULT; AGED; ANTIBODY LABELING; ARTICLE; BLOOD VESSEL; COMPARATIVE STUDY; CONTROLLED STUDY; DENSITY; FEMALE; GRAY MATTER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR DEPRESSION; MALE; MORPHOMETRICS; NISSL STAINING; ORBITAL CORTEX; SUICIDE; VASCULAR DISEASE; WHITE MATTER;

EID: 84881375339     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.3911     Document Type: Article

References (48)

1. Alexopoulos GS,. 2006. The vascular depression hypothesis: 10 years later. Biol Psychiatry 60: 1304-5.
2. Alexopoulos GS, Meyers BS, Young RC, et al,. 1997. Clinically defined vascular depression. Am J Psychiatry 154: 562-5.
3. American Psychiatric Association 1994. Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Association: Washington, D.C.
4. Anderson CM, Nedergaard M,. 2003. Astrocyte-mediated control of cerebral microcirculation. Trend Neurosci 26: 340-4.
5. Attwell D, Buchan AM, Charpak S, et al,. 2010. Glial and neuronal control of brain blood flow. Nature 468: 232-43.
6. Brassen S, Kalisch R, Weber-Fahr W, Braus DF, Buchel C,. 2008. Ventromedial prefrontal cortex processing during emotional evaluation in late-life depression: a longitudinal functional magnetic resonance imaging study. Biol Psychiatry 64: 349-55.
7. Camus V, Kraehenbuhl H, Preisig M, Bula CJ, Waeber G,. 2004. Geriatric depression and vascular diseases: what are the links? J Affect Disord 81: 1-16.
8. Coffey CE, Figiel GS, Djang WT, Saunders WB, Weiner RD,. 1989. White matter hyperintensity on magnetic resonance imaging: clinical and neuroanatomic correlates in the depressed elderly. J Neuropsychiatry Clin Neurosci 1: 135-44.
9. Coffey CE, Figiel GS, Djang WT, Weiner RD,. 1990. Subcortical hyperintensity on magnetic resonance imaging: a comparison of normal and depressed elderly subjects. Am J Psychiatry 147: 187-9.
10. Dejong TM, Overholser JC,. 2009. Assessment of depression and suicidal actions: agreement between suicide attempters and informant reports. Suicide Life Threat Behav 39: 38-46.
11. Drevets WC, Price JL, Furey ML,. 2008. Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct Funct 213: 93-118.
12. Erickson K, Drevets WC, Clark L, et al,. 2005. Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder. Am J Psychiatry 162: 2171-3.
13. Figiel GS, Krishnan KR, Doraiswamy PM, et al,. 1991. Subcortical hyperintensities on brain magnetic resonance imaging: a comparison between late age onset and early onset elderly depressed subjects. Neurobiol Aging 12: 245-7.
14. Grafman J, Schwab K, Warden D, et al,. 1996. Frontal lobe injuries, violence, and aggression: a report of the Vietnam Head Injury Study. Neurology 46: 1231-8.
15. Greenwald B, Kramer-Ginsberg E, Krishnan K, et al,. 1998. Neuroanatomic localization of magnetic resonance imaging signal hyperintensities in geriatric depression. Stroke 29: 613-7.
16. Hamel E,. 2006. Perivascular nerves and the regulation of cerebrovascular tone. J Appl Physiol 100: 1059-64.
17. Herrmann LL, Le Masurier M, Ebmeier KP,. 2008. White matter hyperintensities in late life depression: a systematic review. J Neurol Neurosug Psychiatry 79: 619-624.
18. Krishnan KRR,. 2000. Depression as a contributing factor in cerebrovascular disease. Am Heart J 140: S70-S76.
19. Krishnan KR, Goli V, Ellinwood EH, et al,. 1988. Leukoencephalopathy in patients diagnosed as major depressive. Biol Psychiatry 23: 519-22.
20. Krishnan KR, Taylor WD, Mcquoid DR, et al,. 2004. Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression. Biol Psychiatry 55: 390-7.
21. Kumar A, Miller D,. 1997. Neuroimaging in late-life mood disorders. Clin Neurosci 4: 8-15.
22. Lai T, Payne ME, Byrum CE, Steffens DC, Krishnan KR,. 2000. Reduction of orbital frontal cortex volume in geriatric depression. Biol Psychiatry 48: 971-5.
23. Lee SH, Payne ME, Steffens DC, et al,. 2003. Subcortical lesion severity and orbitofrontal cortex volume in geriatric depression. Biol Psychiatry 54: 529-33.
24. Lesperance F, Frasure-Smith N, Theroux P, Irwin M,. 2004. The association between major depression and levels of soluble intercellular adhesion molecule 1, interleukin-6, and C-reactive protein in patients with recent acute coronary syndromes. Am J Psychiatry 161: 271-7.
25. Lesser IM, Mena I, Boone KB, et al,. 1994. Reduction of cerebral blood flow in older depressed patients. Arch Gen Psychiatry 51: 677-86.
26. Macfall JR, Payne ME, Provenzale JE, Krishnan KR,. 2001. Medial orbital frontal lesions in late-onset depression. Biol Psychiatry 49: 803-6.
27. Miguel-Hidalgo JJ, Rajkowska G,. 1999. Immunohistochemistry of neural markers for the study of the laminar architecture in celloidin sections from the human cerebral cortex. J Neurosci Meth 93: 69-79.
28. Munoz DG, Hastak SM, Harper B, Lee D, Hachinski VC,. 1993. Pathologic correlates of increased signals of the centrum ovale on magnetic resonance imaging. Arch Neurol 50: 492-7.
29. Ordway GA, Szebeni A, Chandley MJ, et al,. 2011. Low gene expression of bone morphogenetic protein 7 in brainstem astrocytes in major depression. Int J Neuropsychopharmacol 15: 855-868.
30. Rajkowska G, Goldman-Rakic PS,. 1995. Cytoarchitectonic definition of prefrontal areas in the normal human cortex: I. quantitative criteria for distinguishing areas 9 and 46. Cereb Cortex 4: 307-322.
31. Rajkowska G, Miguel-Hidalgo JJ, Wei J, et al,. 1999. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol Psychiatry 45: 1085-98.
32. Rajkowska G, Miguel-Hidalgo JJ, Dubey P, Stockmeier CA, Krishnan KRR,. 2005. Prominent reduction in pyramidal neurons density in the orbitofrontal cortex of elderly depressed patients. Biol Psychiatry 58: 297-306.
33. Sandor P,. 1999. Nervous control of the cerebrovascular system: doubts and facts. Neurochem Int 35: 237-59.
34. Savitz J, Van Der Merwe L, Solms M, Ramesar R,. 2007. Neurocognitive function in an extended Afrikaner-ancestry family with affective illness. J Psychiatry Neurosci 32: 116-20.
35. Steffens D, Krishnan K,. 1998. Structural neuroimaging and mood disorders: recent findings, implications for classification, and future directions. Biol Psychiatry 43: 705-12.
36. Steffens DC, Helms MJ, Krishnan KR, Burke GL,. 1999. Cerebrovascular disease and depression symptoms in the cardiovascular health study. Stroke 30: 2159-66.
37. Stockmeier CA, Shapiro LA, Dilley GE, et al,. 1998. Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity. J Neurosci 18: 7394-401.
38. Taylor WD, Krishnan RR,. 2003. Affective disorders: imaging studies. In Handbook of Medical Psychiatry, Soares JC, Gershon S, (eds.) Marcel Dekker, Inc: New York.
39. Taylor WD, Payne ME, Krishnan KR, et al,. 2001. Evidence of white matter tract disruption in MRI hyperintensities. Biol Psychiatry 50: 179-83.
40. Taylor WD, Macfall JR, Steffens DC, et al,. 2003a. Localization of age-associated white matter hyperintensities in late-life depression. Prog Neuropsychopharmacol Biol Psychiatry 27: 539-44.
41. Taylor WD, Steffens DC, Macfall JR, et al,. 2003b. White matter hyperintensity progression and late-life depression outcomes. Arch Gen Psychiatry 60: 1090-1096.
42. Thomas AJ, Ferrier IN, Kalaria RN, et al,. 2000. Elevation in late-life depression of intercellular adhesion molecule-1 expression in the dorsolateral prefrontal cortex. Am J Psychiatry 157: 1682-4.
43. Thomas AJ, Ferrier IN, Kalaria RN, et al,. 2001. A neuropathological study of vascular factors in late-life depression. J Neurol Neurosurg Psychiatry 70: 83-87.
44. Thomas AJ, Ferrier IN, Kalaria RN, Davis S, O'brien JT,. 2002a. Cell adhesion molecule expression in the dorsolateral prefrontal cortex and anterior cingulate cortex in major depression in the elderly. Br J Psychiatry 181: 129-34.
45. Thomas AJ, O'brien JT, Davis S, et al,. 2002b. Ischemic basis for deep white matter hyperintensities in major depression: a neuropathological study. Arch Gen Psychiatry 59: 785-92.
46. Thomas AJ, O'brien JT, Barber R, Mcmeekin W, Perry R,. 2003. A neuropathological study of periventricular white matter hyperintensities in major depression. J Affect Disord 76: 49-54.
47. Uylings HB, Sanz-Arigita EJ, De Vos K, et al,. 2010. 3-D cytoarchitectonic parcellation of human orbitofrontal cortex correlation with postmortem MRI. Psychiatry Res 183: 1-20.
48. Vaishnavi S, Taylor WD,. 2006. Neuroimaging in late-life depression. Int Rev Psychiatry 18: 443-51.