Neurocognitive function in an extended Afrikaner-ancestry family with affective illness

Journal of Psychiatry and Neuroscience

Volumn 32, Issue 2, 2007, Pages 116-120

  Savitz, Jonathan ^a   Van Der Merwe, Lize ^b   Solms, Mark ^a   Ramesar, Rajkumar ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

Author keywords

Affective illness; Afrikaner ancestry; Bipolar disorder; Unipolar depression

Indexed keywords

ADULT; AGED; ARTICLE; BIPOLAR DISORDER; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EXTENDED FAMILY; FEMALE; HUMAN; MAJOR DEPRESSION; MALE; MOOD DISORDER; SOCIOECONOMICS; VERBAL MEMORY; VISUAL MEMORY; ADOLESCENT; ATTENTION; COGNITIVE DEFECT; COLOR VISION; CONFLICT; GENETICS; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PHENOTYPE; PROBLEM SOLVING; PSYCHOLOGICAL ASPECT; RECURRENT DISEASE; SEMANTICS; SOUTH AFRICA;

ADOLESCENT; ADULT; ATTENTION; BIPOLAR DISORDER; COGNITION DISORDERS; COLOR PERCEPTION; CONFLICT (PSYCHOLOGY); DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PHENOTYPE; PROBLEM SOLVING; RECURRENCE; SEMANTICS; SOUTH AFRICA;

EID: 34247135805     PISSN: 11804882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. st centuries: statistical methods, data analysis and experimental design. Hum Biol 2000;72:63-132.
2. Gottesman II, Gould TD. the endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003;160:636-45.
3. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. Washington: The Association; 1994.
4. Egan MF, Goldberg TE, Kolachana BS, et al. Effect of COMT Val108/158Met genotype on frontal lobe function and risk for schizophrenia. Proc Natl Acad Sci U S A 2001;98:6917-22.
5. Savitz JB, Solms M, Ramesar RS. Neurocognitive function as an endophenotype for genetic studies of bipolar affective disorder. Neuromolecular Med 2005;7:275-86.
6. Savitz J, Solms M, Ramesar R. Neuropsychological deficits in bipolar affective disorder: a critical opinion. Bipolar Disord 2005;7:216-35.
7. Ferrier IN, Thompson JM. Cognitive impairment in bipolar affective disorder: implications for the bipolar diathesis. Br J Psychiatry 2002;180:293-5.
8. Clark L, Goodwin GM. State and trait-related deficits in sustained attention in bipolar disorder. Eur Arch Psychiatry Clin Neurosci 2004;254:61-8.
9. Paelecke-Habermann Y, Pohl J, Leplow B. Attention and executive functions in remitted major depression patients. J Affect Disord 2005;89:125-35.
10. Altshuler LL, Ventura J, van Gorp WG, et al. Neurocognitive function in clinically stable men with bipolar i disorder or schizophrenia and normal control subjects. Biol Psychiatry 2004;56:560-9.
11. Thompson JM, Gallagher P, Hughes JH, et al. Neurocognitive impairment in euthymic patients with bipolar affective disorder. Br J Psychiatry 2005;186:32-40.
12. Abecasis GR, Burt RA, Hall D, et al. Genomewide scan in families with schizophrenia from the founder population of Afrikaners reveals evidence for linkage and uniparental disomy on chromosome1. Am J Hum Genet 2004;74:403-17.
13. First MB, Spitzer RL, Gibbon M, et al. (1996). Structured Clinical Interview for the DSM-IV, Patient Edition. SCID-I/P (Version 2.0). Modified for the Norvatis Bipolar Disorder Genetic Study: January 7, 1998.
14. Trichard C, Martinot JL, Alagille M, et al. Time course of pre-frontal lobe dysfunction in severely depressed in-patients: a longitudinal neuropsychological study. Psychol Med 1995;25:79-85.
15. Paradiso S, Lamberty GJ, Garvey MJ, et al. Cognitive impairment in the euthymic phase of chronic unipolar depression. J Nerv Ment Dis 1997;185:748-54.
16. Liu SK, Chiu CH, Chang CJ, et al. Deficits in sustained attention in schizophrenia and affective disorders: Stable versus state-dependent markers. Am J Psychiatry 2002;159:975-82.
17. Biringer E, Lundervold A, Stordal K, et al. Executive function improvement upon remission of recurrent unipolar depression. Eur Arch Psychiatry Clin Neurosci 2005;255:373-80.
18. Ali SO, Denicoff KD, Altshuler LL, et al. A preliminary study of the relation of neuropsychological performance to neuroanatomic structures in bipolar disorder. Neuropsychiatry Neuropsychol Behav Neurol 2000;13:20-8.
19. Zubieta JK, Huguelet P, O'Neil RL, et al. Cognitive function in euthymic bipolar I disorder. Psychiatry Res 2001;102:9-20.
20. Martinez-Aran A, Vieta E, Reinares M, et al. Cognitive function across manic or hypomanic, depressed, and euthymic states in bipolar disorder. Am J Psychiatry 2004;161:262-70.
21. Zalla T, Joyce C, Szoke A, et al. Executive dysfunctions as potential markers of familial vulnerability to bipolar disorder and schizophrenia. Psychiatry Res 2004;121:207-17.
22. van Gorp WG, Altshuler L, Theberge DC, et al. Cognitive impairment in euthymic bipolar patients with and without prior alcohol dependence. Arch Gen Psychiatry 1998;55:41-6.
23. Krabbendam L, Honig A, Wiersma J, et al. Cognitive dysfunctions and white matter lesions in patients with bipolar disorder in remission. Acta Psychiatr Scand 2000;101:274-80.
24. Cavanagh JTO, Van Beck M, Muir W, et al. Case-control study of neurocognitive function in euthymic patients with bipolar disorder: an association with mania. Br J Psychiatry 2002;180:320-6.
25. Robinson LJ, Thompson JM, Gallagher P, et al. A meta-analysis of cognitive deficits in euthymic patients with bipolar disorder. J Affect Disord. In press.