SCOPUS 정보 검색 플랫폼

Volumn 21, Issue 17, 2013, Pages 5175-5181

Synthesis and initial in vitro biological evaluation of two new zinc-chelating compounds: Comparison with TPEN and PAC-1

(6) Åstrand, O Alexander H a Aziz, Gulzeb a Ali, Sidra Farzand a Paulsen, Ragnhild E a Hansen, Trond Vidar a Rongved, Pål a

a UNIVERSITY OF OSLO (Norway)

Author keywords

Apoptosis; Caspase 3 activation; PAC 1 analogues; ROS production; Zinc chelators

Indexed keywords

2 (4 BENZYLPIPERAZIN 1 YL) N' [2 [BIS(PYRIDIN 2 YLMETHYL)AMINO]ACETYL]ACETOHYDRAZIDE; 2 (4 BENZYLPIPERAZIN 1 YL) N' [[3 HYDROXY 5 (HYDROXYMETHYL) 2 METHYLPYRIDIN 4 YL]METHYLENE]ACETOHYDRAZIDE; CASPASE 3; CHELATING AGENT; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; PROCASPASE 3; PROCASPASE ACTIVATING COMPOUND; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ZINC; ZINC SULFATE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING KINETICS; CELL TYPE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; IN VITRO STUDY; LIPOPHILICITY; NONHUMAN; PC12 CELL; RAT;

RATTUS;

APOPTOSIS; CASPASE-3 ACTIVATION; CVRXLMUYFMERMJ-UHFFFAOYSA-N; PAC-1 ANALOGUES; QFPVDYVNRNGXRQ-FSJBWODESA-N; ROS PRODUCTION; UBFPFEYJQOUETN-UHFFFAOYSA-N; YQNRVGJCPCNMKT-LFVJCYFKSA-N; ZINC CHELATORS;

AMINES; ANIMALS; APOPTOSIS; CASPASE 3; CASPASE INHIBITORS; CHELATING AGENTS; ETHYLENEDIAMINES; HYDRAZONES; PC12 CELLS; PICOLINIC ACIDS; PIPERAZINES; PYRIDOXINE; RATS; REACTIVE OXYGEN SPECIES; ZINC; ZINC SULFATE;

EID: 84881370895 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.06.037 Document Type: Article

Times cited : (17)

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