Zinc depletion efficiently inhibits pancreatic cancer cell growth by increasing the ratio of antiproliferative/proliferative genes

Journal of Cellular Biochemistry

Volumn 104, Issue 1, 2008, Pages 202-212

  Donadelli, M ^a   Dalla Pozza, E ^a   Costanzo, C ^a   Scupoli, M T ^a   Scarpa, A ^a   Palmieri, M ^a,b  

^a UNIVERSITY OF VERONA   (Italy)

^b Department of Morphological and Biomedical Sciences   (Italy)

Author keywords

Apoptosis; Cell cycle; N,N,N ,N tetrakis(2 pyridylmethyl)ethylenediamine (TPEN); Pancreatic adenocarcinoma; Zinc

Indexed keywords

AXXORA; CASPASE 3; CASPASE 8; CISPLATIN; CYCLIN DEPENDENT KINASE 2 INHIBITOR; CYCLINE; EDELFOSINE; FLUOROURACIL; GEMCITABINE; IRINOTECAN; MITOMYCIN C; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; TRICHOSTATIN A; UNCLASSIFIED DRUG; ZINC; CHELATING AGENT; ETHYLENEDIAMINE DERIVATIVE; N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)ETHYLENEDIAMINE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DAMAGE; CELL VIABILITY; CHRONOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENZYME ACTIVATION; FIBROBLAST; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MITOCHONDRION; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; CELL CYCLE; CELL PROLIFERATION; GENE EXPRESSION REGULATION; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHELATING AGENTS; ETHYLENEDIAMINES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PANCREATIC NEOPLASMS; ZINC;

EID: 46449130108     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21613     Document Type: Article

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