메뉴 건너뛰기




Volumn 8, Issue 8, 2013, Pages

Basement Membrane-Rich Organoids with Functional Human Blood Vessels Are Permissive Niches for Human Breast Cancer Metastasis

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RENILLA LUCIFERIN 2 MONOOXYGENASE;

EID: 84881363012     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072957     Document Type: Article
Times cited : (14)

References (39)
  • 1
    • 23144442644 scopus 로고    scopus 로고
    • Breast cancer metastasis: markers and models
    • doi: 10.1038/nrc1670
    • Weigelt B, Peterse JL, van 't Veer LJ, (2005) Breast cancer metastasis: markers and models. Nat Rev Cancer 5: 591-602. doi:10.1038/nrc1670. PubMed: 16056258.
    • (2005) Nat Rev Cancer , vol.5 , pp. 591-602
    • Weigelt, B.1    Peterse, J.L.2    van 't Veer, L.J.3
  • 2
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: from dissemination to organ-specific colonization
    • doi: 10.1038/nrc2622
    • Nguyen DX, Bos PD, Massagué J, (2009) Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 9: 274-284. doi:10.1038/nrc2622. PubMed: 19308067.
    • (2009) Nat Rev Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massagué, J.3
  • 3
    • 34548575794 scopus 로고    scopus 로고
    • Tumour dormancy in breast cancer: an update
    • doi: 10.1186/bcr1677
    • Brackstone M, Townson JL, Chambers AF, (2007) Tumour dormancy in breast cancer: an update. Breast Cancer Res 9: 208. doi:10.1186/bcr1677. PubMed: 17561992.
    • (2007) Breast Cancer Res , vol.9 , pp. 208
    • Brackstone, M.1    Townson, J.L.2    Chambers, A.F.3
  • 4
    • 77950518404 scopus 로고    scopus 로고
    • Mouse models for breast cancer metastasis
    • doi: 10.1016/j.bbrc.2010.03.070
    • Kim IS, Baek SH, (2010) Mouse models for breast cancer metastasis. Biochem Biophys Res Commun 394: 443-447. doi:10.1016/j.bbrc.2010.03.070. PubMed: 20230796.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 443-447
    • Kim, I.S.1    Baek, S.H.2
  • 5
    • 34648832906 scopus 로고    scopus 로고
    • Illuminating the metastatic process
    • doi: 10.1038/nrc2229
    • Sahai E, (2007) Illuminating the metastatic process. Nat Rev Cancer 7: 737-749. doi:10.1038/nrc2229. PubMed: 17891189.
    • (2007) Nat Rev Cancer , vol.7 , pp. 737-749
    • Sahai, E.1
  • 6
    • 41949131865 scopus 로고    scopus 로고
    • Long-term in vivo imaging of human angiogenesis: critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels
    • doi: 10.1016/j.mvr.2007.11.007
    • Sanz L, Santos-Valle P, Alonso-Camino V, Salas C, Serrano A, et al. (2008) Long-term in vivo imaging of human angiogenesis: critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels. Microvasc Res 75: 308-314. doi:10.1016/j.mvr.2007.11.007. PubMed: 18252255.
    • (2008) Microvasc Res , vol.75 , pp. 308-314
    • Sanz, L.1    Santos-Valle, P.2    Alonso-Camino, V.3    Salas, C.4    Serrano, A.5
  • 7
    • 47149102903 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature
    • doi: 10.1182/blood-2007-10-118273
    • Au P, Tam J, Fukumura D, Jain RK, (2008) Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood 111: 4551-4558. doi:10.1182/blood-2007-10-118273. PubMed: 18256324.
    • (2008) Blood , vol.111 , pp. 4551-4558
    • Au, P.1    Tam, J.2    Fukumura, D.3    Jain, R.K.4
  • 8
    • 34249732615 scopus 로고    scopus 로고
    • In vivo vasculogenic potential of human blood-derived endothelial progenitor cells
    • doi: 10.1182/blood-2006-12-062471
    • Melero-Martin JM, Khan ZA, Picard A, Wu X, Paruchuri S, et al. (2007) In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Blood 109: 4761-4768. doi:10.1182/blood-2006-12-062471. PubMed: 17327403.
    • (2007) Blood , vol.109 , pp. 4761-4768
    • Melero-Martin, J.M.1    Khan, Z.A.2    Picard, A.3    Wu, X.4    Paruchuri, S.5
  • 9
    • 48849109338 scopus 로고    scopus 로고
    • Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells
    • doi: 10.1161/CIRCRESAHA.108.178590
    • Melero-Martin JM, De Obaldia ME, Kang S-Y, Khan ZA, Yuan L, et al. (2008) Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Circ Res 103: 194-202. doi:10.1161/CIRCRESAHA.108.178590. PubMed: 18556575.
    • (2008) Circ Res , vol.103 , pp. 194-202
    • Melero-Martin, J.M.1    De Obaldia, M.E.2    Kang, S.-Y.3    Khan, Z.A.4    Yuan, L.5
  • 10
    • 77953477857 scopus 로고    scopus 로고
    • Factory neovessels: engineered human blood vessels secreting therapeutic proteins as a new drug delivery system
    • doi: 10.1038/gt.2010.33
    • Compte M, Alonso-Camino V, Santos-Valle P, Cuesta AM, Sánchez-Martín D, et al. (2010) Factory neovessels: engineered human blood vessels secreting therapeutic proteins as a new drug delivery system. Gene Ther 17: 745-751. doi:10.1038/gt.2010.33. PubMed: 20336155.
    • (2010) Gene Ther , vol.17 , pp. 745-751
    • Compte, M.1    Alonso-Camino, V.2    Santos-Valle, P.3    Cuesta, A.M.4    Sánchez-Martín, D.5
  • 11
    • 33947264398 scopus 로고    scopus 로고
    • Inhibition of tumor growth in vivo by in situ secretion of bispecific anti-CEA x anti-CD3 diabodies from lentivirally transduced human lymphocytes
    • doi: 10.1038/sj.cgt.7701021
    • Compte M, Blanco B, Serrano F, Cuesta AM, Sanz L, et al. (2007) Inhibition of tumor growth in vivo by in situ secretion of bispecific anti-CEA x anti-CD3 diabodies from lentivirally transduced human lymphocytes. Cancer Gene Ther 14: 380-388. doi:10.1038/sj.cgt.7701021. PubMed: 17218946.
    • (2007) Cancer Gene Ther , vol.14 , pp. 380-388
    • Compte, M.1    Blanco, B.2    Serrano, F.3    Cuesta, A.M.4    Sanz, L.5
  • 12
    • 78650797767 scopus 로고    scopus 로고
    • Engineered human tumor xenografts with functional human vascular networks
    • doi: 10.1016/j.mvr.2010.10.002
    • Alonso-Camino V, Santos-Valle P, Ispizua MC, Sanz L, Alvarez-Vallina L, (2011) Engineered human tumor xenografts with functional human vascular networks. Microvasc Res 81: 18-25. doi:10.1016/j.mvr.2010.10.002. PubMed: 20934439.
    • (2011) Microvasc Res , vol.81 , pp. 18-25
    • Alonso-Camino, V.1    Santos-Valle, P.2    Ispizua, M.C.3    Sanz, L.4    Alvarez-Vallina, L.5
  • 13
    • 0032477786 scopus 로고    scopus 로고
    • De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor
    • doi: 10.1073/pnas.95.3.1062
    • Kawaguchi N, Toriyama K, Nicodemou-Lena E, Inou K, Torii S, et al. (1998) De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor. Proc Natl Acad Sci U S A 95: 1062-1066. doi:10.1073/pnas.95.3.1062. PubMed: 9448285.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 1062-1066
    • Kawaguchi, N.1    Toriyama, K.2    Nicodemou-Lena, E.3    Inou, K.4    Torii, S.5
  • 14
    • 62549151252 scopus 로고    scopus 로고
    • Why are tumour blood vessels abnormal and why is it important to know?
    • doi: 10.1038/sj.bjc.6604929
    • Nagy JA, Chang S-H, Dvorak AM, Dvorak HF, (2009) Why are tumour blood vessels abnormal and why is it important to know? Br J Cancer 100: 865-869. doi:10.1038/sj.bjc.6604929. PubMed: 19240721.
    • (2009) Br J Cancer , vol.100 , pp. 865-869
    • Nagy, J.A.1    Chang, S.-H.2    Dvorak, A.M.3    Dvorak, H.F.4
  • 15
    • 23144461051 scopus 로고    scopus 로고
    • Genes that mediate breast cancer metastasis to lung
    • doi: 10.1038/nature03799
    • Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, et al. (2005) Genes that mediate breast cancer metastasis to lung. Nature 436: 518-524. doi:10.1038/nature03799. PubMed: 16049480.
    • (2005) Nature , vol.436 , pp. 518-524
    • Minn, A.J.1    Gupta, G.P.2    Siegel, P.M.3    Bos, P.D.4    Shu, W.5
  • 16
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • doi: 10.1038/nature06188
    • Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, et al. (2007) Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 449: 557-563. doi:10.1038/nature06188. PubMed: 17914389.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3    Sullivan, A.4    Brooks, M.W.5
  • 17
    • 70349497161 scopus 로고    scopus 로고
    • The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art
    • doi: 10.1007/s10456-009-9146-4
    • Arnaoutova I, George J, Kleinman HK, Benton G, (2009) The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art. Angiogenesis 12: 267-274. doi:10.1007/s10456-009-9146-4. PubMed: 19399631.
    • (2009) Angiogenesis , vol.12 , pp. 267-274
    • Arnaoutova, I.1    George, J.2    Kleinman, H.K.3    Benton, G.4
  • 18
    • 77957231341 scopus 로고    scopus 로고
    • The "chemoinvasion" assay, 25 years and still going strong: the use of reconstituted basement membranes to study cell invasion and angiogenesis
    • doi: 10.1016/j.ceb.2010.08.017
    • Albini A, Noonan DM, (2010) The "chemoinvasion" assay, 25 years and still going strong: the use of reconstituted basement membranes to study cell invasion and angiogenesis. Curr Opin Cell Biol 22: 677-689. doi:10.1016/j.ceb.2010.08.017. PubMed: 20822888.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 677-689
    • Albini, A.1    Noonan, D.M.2
  • 19
    • 79951979275 scopus 로고    scopus 로고
    • Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells
    • doi: 10.1002/ijc.25781
    • Benton G, Kleinman HK, George J, Arnaoutova I, (2011) Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells. Int J Cancer 128: 1751-1757. doi:10.1002/ijc.25781. PubMed: 21344372.
    • (2011) Int J Cancer , vol.128 , pp. 1751-1757
    • Benton, G.1    Kleinman, H.K.2    George, J.3    Arnaoutova, I.4
  • 20
    • 77956399506 scopus 로고    scopus 로고
    • Matrigel: a complex protein mixture required for optimal growth of cell culture
    • doi: 10.1002/pmic.200900758
    • Hughes CS, Postovit LM, Lajoie GA, (2010) Matrigel: a complex protein mixture required for optimal growth of cell culture. Proteomics 10: 1886-1890. doi:10.1002/pmic.200900758. PubMed: 20162561.
    • (2010) Proteomics , vol.10 , pp. 1886-1890
    • Hughes, C.S.1    Postovit, L.M.2    Lajoie, G.A.3
  • 21
    • 38349091953 scopus 로고    scopus 로고
    • Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis
    • doi: 10.1242/dev.011171
    • Patel VN, Knox SM, Likar KM, Lathrop CA, Hossain R, et al. (2007) Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis. Development 134: 4177-4186. doi:10.1242/dev.011171. PubMed: 17959718.
    • (2007) Development , vol.134 , pp. 4177-4186
    • Patel, V.N.1    Knox, S.M.2    Likar, K.M.3    Lathrop, C.A.4    Hossain, R.5
  • 22
    • 33747843457 scopus 로고    scopus 로고
    • The engineering of endovascular stent technology: a review
    • doi: 10.1177/153857440604000201
    • Whittaker DR, Fillinger MF, (2006) The engineering of endovascular stent technology: a review. Vasc Endovasc Surg 40: 85-94. doi:10.1177/153857440604000201. PubMed: 16598355.
    • (2006) Vasc Endovasc Surg , vol.40 , pp. 85-94
    • Whittaker, D.R.1    Fillinger, M.F.2
  • 23
    • 84857641315 scopus 로고    scopus 로고
    • Basement membrane matrix (BME) has multiple uses with stem cells
    • doi: 10.1007/s12015-011-9278-y
    • Arnaoutova I, George J, Kleinman HK, Benton G, (2012) Basement membrane matrix (BME) has multiple uses with stem cells. Stem Cell Rev 8: 163-169. doi:10.1007/s12015-011-9278-y. PubMed: 21655946.
    • (2012) Stem Cell Rev , vol.8 , pp. 163-169
    • Arnaoutova, I.1    George, J.2    Kleinman, H.K.3    Benton, G.4
  • 24
    • 79551493736 scopus 로고    scopus 로고
    • Proteomics of human embryonic stem cells
    • doi: 10.1002/pmic.201000407
    • Hughes CS, Nuhn AA, Postovit LM, Lajoie GA, (2011) Proteomics of human embryonic stem cells. Proteomics 11: 675-690. doi:10.1002/pmic.201000407. PubMed: 21225999.
    • (2011) Proteomics , vol.11 , pp. 675-690
    • Hughes, C.S.1    Nuhn, A.A.2    Postovit, L.M.3    Lajoie, G.A.4
  • 25
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: A dynamic niche in cancer progression
    • doi: 10.1083/jcb.201102147
    • Lu P, Weaver VM, Werb Z, (2012) The extracellular matrix: A dynamic niche in cancer progression. J Cell Biol 196: 395-406. doi:10.1083/jcb.201102147. PubMed: 22351925.
    • (2012) J Cell Biol , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 26
    • 28644432204 scopus 로고    scopus 로고
    • VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
    • doi: 10.1038/nature04186
    • Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, et al. (2005) VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438: 820-827. doi:10.1038/nature04186. PubMed: 16341007.
    • (2005) Nature , vol.438 , pp. 820-827
    • Kaplan, R.N.1    Riba, R.D.2    Zacharoulis, S.3    Bramley, A.H.4    Vincent, L.5
  • 27
    • 84855425160 scopus 로고    scopus 로고
    • Interactions between cancer stem cells and their niche govern metastatic colonization
    • 22158103
    • Malanchi I, Santamaria-Martínez A, Susanto E, Peng H, Lehr H-A, et al. (2012) Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 481: 85-89. PubMed: 22158103.
    • (2012) Nature , vol.481 , pp. 85-89
    • Malanchi, I.1    Santamaria-Martínez, A.2    Susanto, E.3    Peng, H.4    Lehr, H.-A.5
  • 28
    • 84857189202 scopus 로고    scopus 로고
    • Extracellular matrix players in metastatic niches
    • 22179697
    • Oskarsson T, Massagué J, (2012) Extracellular matrix players in metastatic niches. EMBO J 31: 254-256. PubMed: 22179697.
    • (2012) EMBO J , vol.31 , pp. 254-256
    • Oskarsson, T.1    Massagué, J.2
  • 29
    • 84858199187 scopus 로고    scopus 로고
    • Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition
    • doi: 10.1158/1538-7445.AM2012-1384
    • Gao D, Joshi N, Choi H, Ryu S, Hahn M, et al. (2012) Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer Res 72: 1384-1394. doi:10.1158/1538-7445.AM2012-1384. PubMed: 22282653.
    • (2012) Cancer Res , vol.72 , pp. 1384-1394
    • Gao, D.1    Joshi, N.2    Choi, H.3    Ryu, S.4    Hahn, M.5
  • 30
    • 47949121662 scopus 로고    scopus 로고
    • Linking inflammation reactions to cancer: novel targets for therapeutic strategies
    • doi: 10.1007/978-0-387-73898-7_9
    • Mantovani A, Marchesi F, Portal C, Allavena P, Sica A, (2008) Linking inflammation reactions to cancer: novel targets for therapeutic strategies. Adv Exp Med Biol 610: 112-127. doi:10.1007/978-0-387-73898-7_9. PubMed: 18593019.
    • (2008) Adv Exp Med Biol , vol.610 , pp. 112-127
    • Mantovani, A.1    Marchesi, F.2    Portal, C.3    Allavena, P.4    Sica, A.5
  • 31
    • 84861191800 scopus 로고    scopus 로고
    • Building the niche: the role of the S100 proteins in metastatic growth
    • doi: 10.1016/j.semcancer.2012.02.006
    • Lukanidin E, Sleeman JP, (2012) Building the niche: the role of the S100 proteins in metastatic growth. Semin Cancer Biol 22: 216-225. doi:10.1016/j.semcancer.2012.02.006. PubMed: 22381352.
    • (2012) Semin Cancer Biol , vol.22 , pp. 216-225
    • Lukanidin, E.1    Sleeman, J.P.2
  • 32
    • 33751504690 scopus 로고    scopus 로고
    • Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
    • doi: 10.1038/ncb1507
    • Hiratsuka S, Watanabe A, Aburatani H, Maru Y, (2006) Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol 8: 1369-1375. doi:10.1038/ncb1507. PubMed: 17128264.
    • (2006) Nat Cell Biol , vol.8 , pp. 1369-1375
    • Hiratsuka, S.1    Watanabe, A.2    Aburatani, H.3    Maru, Y.4
  • 33
    • 63049121364 scopus 로고    scopus 로고
    • The metastatic niche: adapting the foreign soil
    • doi: 10.1038/nrc2621
    • Psaila B, Lyden D, (2009) The metastatic niche: adapting the foreign soil. Nat Rev Cancer 9: 285-293. doi:10.1038/nrc2621. PubMed: 19308068.
    • (2009) Nat Rev Cancer , vol.9 , pp. 285-293
    • Psaila, B.1    Lyden, D.2
  • 34
    • 78650739435 scopus 로고    scopus 로고
    • Malignant cells facilitate lung metastasis by bringing their own soil
    • doi: 10.1073/pnas.1016234107
    • Duda DG, Duyverman AMMJ, Kohno M, Snuderl M, Steller EJA, et al. (2010) Malignant cells facilitate lung metastasis by bringing their own soil. Proc Natl Acad Sci U S A 107: 21677-21682. doi:10.1073/pnas.1016234107. PubMed: 21098274.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 21677-21682
    • Duda, D.G.1    Duyverman, A.M.M.J.2    Kohno, M.3    Snuderl, M.4    Steller, E.J.A.5
  • 35
    • 78649889485 scopus 로고    scopus 로고
    • Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression
    • doi: 10.1073/pnas.1004654107
    • DeLisser H, Liu Y, Desprez P-Y, Thor A, Briasouli P, et al. (2010) Vascular endothelial platelet endothelial cell adhesion molecule 1 (PECAM-1) regulates advanced metastatic progression. Proc Natl Acad Sci USA 107: 18616-18621. doi:10.1073/pnas.1004654107. PubMed: 20926749.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 18616-18621
    • DeLisser, H.1    Liu, Y.2    Desprez, P.-Y.3    Thor, A.4    Briasouli, P.5
  • 36
    • 84871942211 scopus 로고    scopus 로고
    • Cdc42 promotes transendothelial migration of cancer cells through β1 integrin
    • Reymond N, Im JH, Garg R, Vega FM, Borda d'Agua B, et al. (2012) Cdc42 promotes transendothelial migration of cancer cells through β1 integrin. J Cell Biol 199: 653-668.
    • (2012) J Cell Biol , vol.199 , pp. 653-668
    • Reymond, N.1    Im, J.H.2    Garg, R.3    Vega, F.M.4    Borda d'Agua, B.5
  • 37
    • 33846938312 scopus 로고    scopus 로고
    • Mouse models of breast cancer metastasis
    • doi: 10.1186/bcr1530
    • Fantozzi A, Christofori G, (2006) Mouse models of breast cancer metastasis. Breast Cancer Res 8: 212. doi:10.1186/bcr1530. PubMed: 16887003.
    • (2006) Breast Cancer Res , vol.8 , pp. 212
    • Fantozzi, A.1    Christofori, G.2
  • 38
    • 22244455403 scopus 로고    scopus 로고
    • A mouse model of human breast cancer metastasis to human bone
    • doi: 10.1158/0008-5472.CAN-04-1408
    • Kuperwasser C, Dessain S, Bierbaum BE, Garnet D, Sperandio K, et al. (2005) A mouse model of human breast cancer metastasis to human bone. Cancer Res 65: 6130-6138. doi:10.1158/0008-5472.CAN-04-1408. PubMed: 16024614.
    • (2005) Cancer Res , vol.65 , pp. 6130-6138
    • Kuperwasser, C.1    Dessain, S.2    Bierbaum, B.E.3    Garnet, D.4    Sperandio, K.5
  • 39
    • 58149117928 scopus 로고    scopus 로고
    • Differential transplantability of human endothelial cells in colorectal cancer and renal cell carcinoma primary xenografts
    • doi: 10.1038/labinvest.2008.108
    • Sanz L, Cuesta AM, Salas C, Corbacho C, Bellas C, et al. (2009) Differential transplantability of human endothelial cells in colorectal cancer and renal cell carcinoma primary xenografts. Lab Invest 89: 91-97. doi:10.1038/labinvest.2008.108. PubMed: 19002108.
    • (2009) Lab Invest , vol.89 , pp. 91-97
    • Sanz, L.1    Cuesta, A.M.2    Salas, C.3    Corbacho, C.4    Bellas, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.