In vivo and in silico pharmacokinetics and biodistribution of a melanocortin receptor 1 targeted agent in preclinical models of melanoma

Molecular Pharmaceutics

Volumn 10, Issue 8, 2013, Pages 3175-3185

  Tafreshi, Narges K ^a   Silva, Ariosto ^a   Estrella, Veronica C ^a   McCardle, Timothy W ^a   Chen, Tingan ^a   Jeune Smith, Yolaine ^a   Lloyd, Mark C ^a   Enkemann, Steven A ^a   Smalley, Keiran S M ^a   Sondak, Vernon K ^a   Vagner, Josef ^b   Morse, David L ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

biodistribution; malignant melanoma; Melanocortin 1 receptor; pharmacokinetics; targeted imaging agent

Indexed keywords

MELANOCORTIN 1 RECEPTOR; MESSENGER RNA; PEPTIDOMIMETIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; COMPUTER MODEL; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG TARGETING; DRUG UPTAKE; FEMALE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; KIDNEY; MELANOMA; MOLECULAR PROBE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE DISTRIBUTION; TISSUE MICROARRAY; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MELANOMA; MICE; MODELS, THEORETICAL; MOLECULAR PROBES; RECEPTOR, MELANOCORTIN, TYPE 1; TISSUE ARRAY ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84881362839     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400222j     Document Type: Article

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