Physical Exercise Performance in Temperate and Warm Environments Is Decreased by an Impaired Arterial Baroreflex

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Pires, Washington ^a   Wanner, Samuel P ^a   Lima, Milene R M ^a   Fonseca, Ivana A T ^a   Fumega, Ubirajara ^a   Haibara, Andrea S ^a   Coimbra, Cândido C ^a   Lima, Nilo R V ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; CORE TEMPERATURE; ENVIRONMENTAL FACTOR; EXERCISE TOLERANCE; HEART RATE; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PHYSICAL ACTIVITY; PRESSORECEPTOR REFLEX; RAT; SKIN TEMPERATURE; SYSTOLIC BLOOD PRESSURE; THERMOREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; ARTERIES; BAROREFLEX; BLOOD PRESSURE; BODY TEMPERATURE REGULATION; DENERVATION; HEART RATE; MALE; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, WISTAR; RUNNING; SINOATRIAL NODE; TEMPERATURE;

EID: 84881338562     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072005     Document Type: Article

References (51)

1. Pires W, Wanner SP, La Guardia RB, Rodrigues LO, Silveira SA, et al. (2007) Intracerebroventricular physostigmine enhances blood pressure and heat loss in running rats. J Physiol Pharmacol 58: 3-17. PubMed: 17440222.
2. Pires W, Wanner SP, Lima MR, Oliveira BM, Guimarães JB, et al. (2010) Sinoaortic denervation prevents enhanced heat loss induced by central cholinergic stimulation during physical exercise. Brain Res 1366: 120-128. doi:10.1016/j.brainres.2010.09.110. PubMed: 20933510.
3. Potts JT, (2006) Inhibitory neurotransmission in the nucleus tractus solitarii: implications for baroreflex resetting during exercise. Exp Physiol 91: 59-72. PubMed: 16239249.
4. Rowell LB, O'Leary DS, (1990) Reflex control of the circulation during exercise: chemoreflexes and mechanoreflexes. J Appl Physiol 69: 407-418. PubMed: 2228848.
5. Gallagher KM, Fadel PJ, Smith SA, Strømstad M, Ide K, et al. (2006) The interaction of central command and the exercise pressor reflex in mediating baroreflex resetting during exercise in humans. Exp Physiol 91: 79-87. PubMed: 16263799.
6. Krieger EM, Brum PC, Negrão CE, (1998) Role of arterial baroreceptor function on cardiovascular adjustments to acute and chronic dynamic exercise. Biol Res 31: 273-279. PubMed: 9830515.
7. Waki H, Kasparov S, Katahira K, Shimizu T, Murphy D, et al. (2003) Dynamic exercise attenuates spontaneous baroreceptor reflex sensitivity in conscious rats. Exp Physiol 88: 517-526. doi:10.1113/eph8802545. PubMed: 12861339.
8. Martínez-Nieves B, Collins HL, DiCarlo SE, (2000) Arterial baroreflex regulation of regional vascular conductance at rest and during exercise. Am J Physiol Regul Integr Comp Physiol 278: R1634-R1642. PubMed: 10848533.
9. Collins HL, Kim JK, DiCarlo SE, (2001) Sino-aortic denervation alters the hemodynamic response to exercise in hypertensive rats. Clin Exp Hypertens 23: 657-666. doi:10.1081/CEH-100107395. PubMed: 11728010.
10. Ceroni A, Chaar LJ, Bombein RL, Michelini LC, (2009) Chronic absence of baroreceptor inputs prevents training-induced cardiovascular adjustments in normotensive and spontaneously hypertensive rats. Exp Physiol 94: 630-640. doi:10.1113/expphysiol.2008.046128. PubMed: 19251981.
11. Straznicky NE, Eikelis N, Lambert EA, Esler MD, (2008) Mediators of sympathetic activation in metabolic syndrome obesity. Curr Hypertens Rep 10: 440-447. doi:10.1007/s11906-008-0083-1. PubMed: 18959829.
12. Watkins LL, Surwit RS, Grossman P, Sherwood A, (2000) Is there a glycemic threshold for impaired autonomic control? Diabetes Care 23: 826-830. doi:10.2337/diacare.23.6.826. PubMed: 10841004.
13. Pescatello LS, Franklin BA, Fagard R, Farquhar WB, Kelley GA, et al. (2004) American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc 36: 533-553. doi:10.1249/01.MSS.0000115224.88514.3A. PubMed: 15076798.
14. Sanz C, Gautier JF, Hanaire H, (2010) Physical exercise for the prevention and treatment of type 2 diabetes. Diabetes Metab 36: 346-351. doi:10.1016/j.diabet.2010.06.001. PubMed: 20675173.
15. Noakes TD, (2012) Fatigue is a Brain-Derived Emotion that Regulates the Exercise Behavior to Ensure the Protection of Whole Body Homeostasis. Front Physiol 3: 82. PubMed: 22514538.
16. Lambert EV, St Clair Gibson A, Noakes TD, (2005) Complex systems model of fatigue: integrative homoeostatic control of peripheral physiological systems during exercise in humans. Br J Sports Med 39: 52-62. doi:10.1136/bjsm.2003.011247. PubMed: 15618343.
17. Nybo L, (2008) Viewpoint: Fatigue mechanisms determining exercise performance: integrative physiology is systems physiology. J Appl Physiol 104: 1543-1544. doi:10.1152/japplphysiol.90427.2008. PubMed: 185048171850481618450996.
18. Marcora S, (2010) Counterpoint: Afferent feedback from fatigued locomotor muscles is not an important determinant of endurance exercise performance. J Appl Physiol 108: 454-456; discussion 456-457 doi:10.1152/japplphysiol.00976.2009a. PubMed: 20118347.
19. Cheuvront SN, Kenefick RW, Montain SJ, Sawka MN, (2010) Mechanisms of aerobic performance impairment with heat stress and dehydration. J Appl Physiol 109: 1989-1995. doi:10.1152/japplphysiol.00367.2010. PubMed: 20689090.
20. Kregel KC, Johnson DG, Tipton CM, Seals DR, (1990) Arterial baroreceptor reflex modulation of sympathetic-cardiovascular adjustments to heat stress. Hypertension 15: 497-504. doi:10.1161/01.HYP.15.5.497. PubMed: 2332240.
21. Leon LR, Helwig BG, (2010) Heat stroke: role of the systemic inflammatory response. J Appl Physiol 109: 1980-1988. doi:10.1152/japplphysiol.00301.2010. PubMed: 20522730.
22. Krieger EM, (1964) Neurogenic Hypertension in the Rat. Circ Res 15: 511-521. doi:10.1161/01.RES.15.6.511. PubMed: 14243890.
23. Schreihofer AM, Sved AF, (1994) Use of sinoaortic denervation to study the role of baroreceptors in cardiovascular regulation. Am J Physiol 266: R1705-R1710. PubMed: 8203654.
24. Wanner SP, Guimaraes JB, Rodrigues LO, Marubayashi U, Coimbra CC, et al. (2007) Muscarinic cholinoceptors in the ventromedial hypothalamic nucleus facilitate tail heat loss during physical exercise. Brain. Res Bull 73: 28-33. doi:10.1016/j.brainresbull.2007.03.004.
25. Lima MR, Pires W, Fonseca IA, Fonseca CG, Martinelli PM, et al. (2013) Chronic sympathectomy of the caudal artery delays cutaneous heat loss during passive heating. Neurosci Lett 537: 11-16. doi:10.1016/j.neulet.2013.01.013. PubMed: 23347842.
26. Wanner SP, Guimarães JB, Pires W, Marubayashi U, Lima NR, et al. (2011) Muscarinic receptors within the ventromedial hypothalamic nuclei modulate metabolic rate during physical exercise. Neurosci Lett 488: 210-214. doi:10.1016/j.neulet.2010.11.031. PubMed: 21094211.
27. Cerutti C, Barres C, Paultre C, (1994) Baroreflex modulation of blood pressure and heart rate variabilities in rats: assessment by spectral analysis. Am J Physiol 266: H1993-H2000. PubMed: 8203598.
28. Bland JM, Altman DG, (2004) The logrank test. BMJ 328: 1073. doi:10.1136/bmj.328.7447.1073. PubMed: 15117797.
29. Julien C, Chapuis B, Cheng Y, Barrès C, (2003) Dynamic interactions between arterial pressure and sympathetic nerve activity: role of arterial baroreceptors. Am J Physiol Regul Integr Comp Physiol 285: R834-R841. PubMed: 12805090.
30. Dworkin BR, Tang X, Snyder AJ, Dworkin S, (2000b) Carotid and aortic baroreflexes of the rat: II. Open-loop frequency response and the blood pressure spectrum. Am J Physiol Regul Integr Comp Physiol 279: R1922-R1933.
31. Goldstein DS, Bentho O, Park MY, Sharabi Y, (2011) Low-frequency power of heart rate variability is not a measure of cardiac sympathetic tone but may be a measure of modulation of cardiac autonomic outflows by baroreflexes. Exp Physiol 96: 1255-1261. PubMed: 21890520.
32. Noakes TD, (2000) Physiological models to understand exercise fatigue and the adaptations that predict or enhance athletic performance. Scand J Med Sci Sports 10: 123-145. doi:10.1034/j.1600-0838.2000.010003123.x. PubMed: 10843507.
33. Shan ZZ, Dai SM, Fang F, Su DF, (2004) Changes of central norepinephrine, beta-endorphin, LEU-enkephalin, peripheral arginine-vasopressin, and angiotensin II levels in acute and chronic phases of sino-aortic denervation in rats. J Cardiovasc Pharmacol 43: 234-241. doi:10.1097/00005344-200402000-00011. PubMed: 14716211.
34. Stebbins CL, Symons JD, (1993) Vasopressin contributes to the cardiovascular response to dynamic exercise. Am J Physiol 264: H1701-H1707. PubMed: 8498582.
35. Wade CE, (1984) Response, regulation, and actions of vasopressin during exercise: a review. Med Sci Sports Exerc 16: 506-511. doi:10.1249/00005768-198410000-00015. PubMed: 6392809.
36. Dworkin BR, Dworkin S, Tang X, (2000a) Carotid and aortic baroreflexes of the rat: I. Open-loop steady-state properties and blood pressure variability. Am J Physiol Regul Integr Comp Physiol 279: R1910-R1921.
37. Radaelli A, Castiglioni P, Centola M, Cesana F, Balestri G, et al. (2006) Adrenergic origin of very low-frequency blood pressure oscillations in the unanesthetized rat. Am J Physiol Heart Circ Physiol 290: H357-H364. PubMed: 16143647.
38. Waki H, Katahira K, Polson JW, Kasparov S, Murphy D, et al. (2006) Automation of analysis of cardiovascular autonomic function from chronic measurements of arterial pressure in conscious rats. Exp Physiol 91: 201-213. PubMed: 16239254.
39. Koshiya N, Guyenet PG, (1994) Role of the pons in the carotid sympathetic chemoreflex. Am J Physiol 267: R508-R518. PubMed: 8067462.
40. Kollai M, Koizumi K, (1977) Differential responses in sympathetic outflow evoked by chemoreceptor activation. Brain Res 138: 159-165. doi:10.1016/0006-8993(77)90791-0. PubMed: 589463.
41. Cruz JC, Cavalleri MT, Ceroni A, Michelini LC, (2013) Peripheral chemoreceptors mediate training-induced plasticity in paraventricular nucleus pre-autonomic oxytocinergic neurons. Exp Physiol 98: 386-396. doi:10.1113/expphysiol.2012.065888. PubMed: 22872656.
42. Collins HL, DiCarlo SE, (1993) Cardiac afferents attenuate the muscle metaboreflex in the rat. J Appl Physiol 75: 114-120. PubMed: 8376257.
43. Lieberman DE, Bramble DM, (2007) The evolution of marathon running: capabilities in humans. Sports Med 37: 288-290. doi:10.2165/00007256-200737040-00004. PubMed: 17465590.
44. González-Alonso J, (2012) Human thermoregulation and the cardiovascular system. Exp Physiol 97: 340-346. PubMed: 22227198.
45. Galloway SD, Maughan RJ, (1997) Effects of ambient temperature on the capacity to perform prolonged cycle exercise in man. Med Sci Sports Exerc 29: 1240-1249. doi:10.1097/00005768-199709000-00018. PubMed: 9309637.
46. González-Alonso J, Crandall CG, Johnson JM, (2008) The cardiovascular challenge of exercising in the heat. J Physiol 586: 45-53. PubMed: 17855754.
47. Périard JD, Cramer MN, Chapman PG, Caillaud C, Thompson MW, (2011) Cardiovascular strain impairs prolonged self-paced exercise in the heat. Exp Physiol 96: 134-144. doi:10.1113/expphysiol.2010.054213. PubMed: 20851861.
48. Raven PB, (2008) Recent advances in baroreflex control of blood pressure during exercise in humans: an overview. Med Sci Sports Exerc 40: 2033-2036. doi:10.1249/MSS.0b013e318180bc41. PubMed: 19018210.
49. Fadel PJ, (2008) Arterial baroreflex control of the peripheral vasculature in humans: rest and exercise. Med Sci Sports Exerc 40: 2055-2062. doi:10.1249/MSS.0b013e318180bc80. PubMed: 18981944.
50. Balthazar CH, Leite LH, Rodrigues AG, Coimbra CC, (2009) Performance-enhancing and thermoregulatory effects of intracerebroventricular dopamine in running rats. Pharmacol Biochem Behav 93: 465-469. doi:10.1016/j.pbb.2009.06.009. PubMed: 19549536.
51. Hasegawa H, Piacentini MF, Sarre S, Michotte Y, Ishiwata T, et al. (2008) Influence of brain catecholamines on the development of fatigue in exercising rats in the heat. J Physiol 586: 141-149. PubMed: 17947314.