The interaction of central command and the exercise pressor reflex in mediating baroreflex resetting during exercise in humans

Experimental Physiology

Volumn 91, Issue 1, 2006, Pages 79-87

  Gallagher, Kevin M ^a,d   Fadel, Paul J ^a   Smith, Scott A ^a   Strømstad, Morten ^b   Ide, Kojiro ^b   Secher, Niels H ^b   Raven, Peter B ^c  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b Rigshospitalet   (Denmark)

^c UNIVERSITY OF NORTH TEXAS   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROMUSCULAR BLOCKING AGENT; VECURONIUM;

ADRENERGIC SYSTEM; ADULT; ARTICLE; BLOOD PRESSURE REGULATION; BRAIN FUNCTION; CAROTID ARTERY; CONTROLLED STUDY; FEMALE; HEART RATE; HEART STIMULATION; HUMAN; HUMAN EXPERIMENT; LEG EXERCISE; MALE; MUSCLE CONTRACTION; NEUROMUSCULAR BLOCKING; NORMAL HUMAN; PRESSORECEPTOR REFLEX; STATIC EXERCISE; TASK PERFORMANCE;

EID: 33645093709     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2005.032110     Document Type: Article

References (53)

1. Borg GA 1982 Psychophysical bases of perceived exertion Med Sci Sports Exerc 14 377 381
2. Chen HI & Chang KC 1991 Assessment of threshold and saturation pressure in the baroreflex function curve: a new mathematical analysis Jpn J Physiol 41 861 877
3. Coote JH & Dodds WN 1976 The baroreceptor reflex and the cardiovascular changes associated with sustained muscular contraction in the cat Pflugers Arch 363 167 173
4. Dean C & Seagard JL 1995 Expression of c-Fos protein in the nucleus tractus solitarius in response to physiological activation of carotid baroreceptors Neurosci 69 249 257
5. Ebert TJ 1986 Baroreflex responsiveness is maintained during isometric exercise in humans J Appl Physiol 61 797 803
6. Eckberg DL Cavanaugh MS Mark AL & Abboud FM 1975 A simplified neck suction device for activation of carotid baroreceptors J Lab Clin Med 85 167 173
7. Fadel PJ Ogoh S Keller DM & Raven PB 2003 Recent insights into carotid baroreflex function in humans using the variable pressure neck chamber Exp Physiol 88 671 680
8. Fadel PJ Smith SA & Gallagher KM 2004 Neural mechanisms influencing baroreflex resetting during exercise In Recent Research Developments in Physiology vol. 2 pp. 413 448 Research Signpost Kerala India
9. Gallagher K Fadel P Stromstad M Ide K Smith S Querry R Raven P & Secher N 2001a Effects of partial neuromuscular blockade on carotid baroreflex function during exercise in humans J Physiol 533 861 870
10. Gallagher K Fadel P Stromstad M Ide K Smith S Querry R Raven P & Secher N 2001b Effects of exercise pressor reflex activation on carotid baroreflex function during exercise in humans J Physiol 533 871 880
11. Goodwin GM McCloskey DI & Mitchell JH 1972 Cardiovascular and respiratory responses to changes in central command during isometric exercise at constant muscle tension J Physiol 226 173 190
12. Hammond RL Augustyniak RA Rossi NF Churchill PC Lapanowski K & O'Leary DS 2000 Heart failure alters the strength and mechanisms of the muscle metaboreflex Am J Physiol 278 H818 H828
13. Iellamo F Legramante JM Raimondi G & Peruzzi G 1997 Baroreflex control of sinus node during dynamic exercise in humans: effects of central command and muscle reflexes Am J Physiol 272 H1157 H1164
14. Kalia M Mei SS & Kao FF 1981 Central projections from ergoreceptors (C fibers) in muscle involved in cardiopulmonary responses to static exercise Circ Res 48 I48 I62
15. Kaufman MP Waldrop TG Rybicki KJ Ordway GA & Mitchell JH 1984 Effects of static and rhythmic twitch contractions on the discharge of group III and IV muscle afferents Cardiovasc Res 18 663 668
16. Kazatani Y Hamada M Shigematsu Y Hiwada K & Kokubu T 1995 Beneficial effect of a long-term antihypertensive therapy on blood pressure response to isometric handgrip exercise in patients with essential hypertension Am J Ther 2 165 169
17. Kent BB Drane JW Blumenstein B & Manning JW 1972 A mathematical model to assess changes in the baroreceptor reflex Cardiology 57 295 310
18. Kim JK Augustyniak RA Sala-Mercado JA Hammond RL Ansorge EJ Rossi NF & O'Leary DS 2004 Heart failure alters the strength and mechanisms of arterial baroreflex pressor responses during dynamic exercise Am J Physiol 287 H1682 H1688
19. Kokkinos PF Andreas PE Coutoulakis E Colleran JA Narayan P Dotson CO Choucair W Farmer C & Fernhall B 2002 Determinants of exercise blood pressure response in normotensive and hypertensive women: role of cardiorespiratory fitness J Cardiopulm Rehab 22 178 183
20. Krogh A & Lindhard J 1913 The regulation of respiration and circulation during the initial stages of muscular work J Physiol 47 112 136
21. La Rovere MT Pinna GD Hohnloser SH Marcus FI Mortara A Nohara R Bigger JT Jr. Camm AJ & Schwartz PJ 2001 Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials Circulation 103 2072 2077
22. Legramante JM Massaro M Raimondi G Castrucci F Cassarino S Peruzzi G & Iellamo F 1999 Effect of postural changes on cardiovascular responses to static exercise in hypertensive human beings J Hypertens 17 99 105
23. Leonard B Mitchell JH Mizuno M Rube N Saltin B & Secher NH 1985 Partial neuromuscular blockade and cardiovascular responses to static exercise in man J Physiol 359 365 379
24. Li J Potts JT & Mitchell JH 1998 Effect of barodenervation on c-Fos expression in the medulla induced by static muscle contraction in cats Am J Physiol 274 H901 H908
25. Li J Sinoway AN Gao Z Maile MD Pu M & Sinoway LI 2004 Muscle mechanoreflex and metaboreflex responses after myocardial infarction in rats Circulation 110 3049 3054
26. McCloskey DI & Mitchell JH 1972 Reflex cardiovascular and respiratory response originating in exercising muscle J Physiol 224 173 186
27. McIlveen SA Hayes SG & Kaufman MP 2001 Both central command and exercise pressor reflex reset carotid sinus baroreflex Am J Physiol 280 H1454 H1463
28. Melcher A & Donald DE 1981 Maintained ability of carotid baroreflex to regulate arterial pressure during exercise Am J Physiol 241 H838 H849
29. Middlekauff HR Nitzsche EU Hoh CK Hamilton MA Fonarow CG Hage A & Moriguchi JD 2001 Exaggerated muscle mechanoreflex control of reflex renal vasoconstriction in heart failure J Appl Physiol 90 1714 1719
30. Middlekauff HR Nitzsche EU Hoh CK Hamilton MA Fonarow GC Hage A & Moriguchi JD 2000 Exaggerated renal vasoconstriction during exercise in heart failure patients Circulation 101 784 789
31. Minami N Yoshikawa T Kataoka H Mori N Nagasaka M Kurosawa H Kanazawa M & Kohzuki M 2003 Effects of exercise and beta-blocker on blood pressure and baroreflexes in spontaneously hypertensive rats Am J Hypertens 16 966 972
32. Mittleman MA Maclure M Tofler GH Sherwood JB Goldberg RJ & Muller JE 1993 Triggering of acute myocardial infarction by heavy physical exertion N Engl J Med 329 1677 1683
33. Norton KH Boushel R Strange S Saltin B & Raven PB 1999a Resetting of the carotid arterial baroreflex during dynamic exercise in humans J Appl Physiol 87 332 338
34. Norton KH Gallagher KM Smith SA Querry RG Welch-O'Connor RM & Raven PB 1999b Carotid baroreflex function during prolonged exercise J Appl Physiol 87 339 347
35. Ogoh S Wasmund WL Keller DM O-Yurvati A Gallagher KM Mitchell JH & Raven PB 2002 Role of central command in carotid baroreflex resetting in humans during static exercise J Physiol 543 349 364
36. Papelier Y Escourrou P Gauthier JP & Rowell LB 1994 Carotid baroreflex control of blood pressure and heart rate in men during dynamic exercise J Appl Physiol 77 502 506
37. Pawelczyk JA & Raven PB 1989 Reductions in central venous pressure improve carotid baroreflex responses in conscious men Am J Physiol 257 H1389 H1395
38. Pickering TG 1987 Pathophysiology of exercise hypertension Herz 12 119 124
39. Piepoli M Clark AL Volterrani M Adamopoulos S Sleight P & Coats AJS 1996 Contribution of muscle afferents to the hemodynamic, autonomic, and ventilatory responses to exercise in patients with chronic heart failure: effects of physical training Circulation 93 940 952
40. Ponikowski PP Chua TP Francis DP Capucci A Coats AJS & Piepoli MF 2001 Muscle ergoreceptor overactivity reflects deterioration in clinical status and cardiorespiratory reflex control in chronic heart failure Circulation 104 2324 2330
41. Potts JT Lee SM & Anguelov PI 2002 Tracing of projection neurons from the cervical dorsal horn to the medulla with the anterograde tracer biotinylated dextran amine Auton Neurosci 98 64 69
42. Potts JT & Mitchell JH 1998 Rapid resetting of carotid baroreceptor reflex by afferent input from skeletal muscle receptors Am J Physiol 275 H2000 H2008
43. Potts JT Shi XR & Raven PB 1993 Carotid baroreflex responsiveness during dynamic exercise in humans Am J Physiol 265 H1928 H1938
44. Querry RG Smith SA Stromstad M Ide K Raven PB & Secher NH 2001 Neural blockade during exercise augments central command's contribution to carotid baroreflex resetting Am J Physiol 280 H1635 H1644
45. Rowell LB & O'Leary DS 1990 Reflex control of the circulation during exercise: chemoreflexes and mechanoreflexes J Appl Physiol 69 407 418
46. Smith SA Mammen PPA Mitchell JH & Garry MG 2003a Role of the exercise pressor reflex in rats with dilated cardiomyopathy Circulation 108 1126 1132
47. Smith SA Mitchell JH & Garry MG 2003b Sympathetic blockade abolishes the exaggerated pressor response to muscular contraction in hypertensive rats Med Sci Sports Exerc 35 S109 abstract no. 598
48. Smith SA Querry RG Fadel PJ Gallagher KM Stromstad M Ide K Raven PB & Secher NH 2003c Partial blockade of skeletal muscle somatosensory afferents attenuates baroreflex resetting during exercise in humans J Physiol 551 1013 1021
49. Smith SA Williams MA Mitchell JH Mammen PPA & Garry MG 2005 The capsaicin-sensitive afferent neuron in skeletal muscle is abnormal in heart failure Circulation 111 2056 2065
50. Strange S Secher NH Pawelczyk JA Karpakka J Christensen NJ Mitchell JH & Saltin B 1993 Neural control of cardiovascular responses and of ventilation during dynamic exercise in man J Physiol 470 693 704
51. Waldrop TG Eldridge FL Iwamoto GA & Mitchell JH 1996 Central neural control of respiration and circulation during exercise In Handbook of Physiology, section 12, Exercise: Regulation and Integration of Multiple Systems ed. Rowell LB & Shepherd JT pp. 333 380 American Physiological Society Bethesda MA USA
52. Williamson JW Mitchell JH Olesen HL Raven PB & Secher NH 1994 Reflex increase in blood pressure induced by leg compression in man J Physiol 475 351 357
53. Winchester PK Williamson JW & Mitchell JH 2000 Cardiovascular responses to static exercise in patients with Brown-Sequard syndrome J Physiol 527 193 202