Comparative analysis of folate derived PET imaging agents with [ 18F]-2-fluoro-2-deoxy-d-glucose using a rodent inflammatory paw model

Molecular Pharmaceutics

Volumn 10, Issue 8, 2013, Pages 3103-3111

  Kularatne, Sumith A ^a   Bélanger, Marie José ^b   Meng, Xiangjun ^b   Connolly, Brett M ^b   Vanko, Amy ^b   Suresch, Donna L ^b   Guenther, Ilonka ^b   Wang, Shubing ^b   Low, Philip S ^a   McQuade, Paul ^b   Trotter, Dinko González ^b  

^a PURDUE UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

18F FDG; activated macrophages; folate PET; inflammatory diseases; PET imaging

Indexed keywords

4 FLUOROPHENYLFOLATE F 18; FLUORODEOXYGLUCOSE F 18; FOLATE RECEPTOR 2; FOLATE TETRAXETAN GA 68; FOLIC ACID; GALLIUM 68; TETRAXETAN; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; EXPERIMENTAL MODEL; FOREFOOT; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MACROPHAGE; NONHUMAN; PATIENT MONITORING; PATIENT SELECTION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; RADIOCHEMISTRY; RAT; SIGNAL NOISE RATIO;

ANIMALS; FLUORODEOXYGLUCOSE F18; FOLIC ACID; INFLAMMATION; POSITRON-EMISSION TOMOGRAPHY;

EID: 84881330454     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp4001684     Document Type: Article

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