Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B

Cell Communication and Signaling

Volumn 11, Issue 1, 2013, Pages

  Bakke, Jesse ^a   Bettaieb, Ahmed ^a   Nagata, Naoto ^a   Matsuo, Kosuke ^a   Haj, Fawaz G ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adipocytes; Glucose; Munc18c; PTP1B; SNARE complex

Indexed keywords

MUNC18 PROTEIN; MUNC18C PROTEIN; PROTEIN TYROSINE PHOSPHATASE 1B; SNARE PROTEIN; SYNTAXIN 4; TYROSINE; UNCLASSIFIED DRUG; PTPN1 PROTEIN, MOUSE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISSOCIATION; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBSTRATE; GLUCOSE TRANSPORT; IN VIVO STUDY; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; 3T3 CELL LINE; ANIMAL; METABOLISM; PHOSPHORYLATION; TRANSGENIC MOUSE; CELL STRAIN 3T3;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; DIET, HIGH-FAT; MALE; MICE; MICE, TRANSGENIC; MUNC18 PROTEINS; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; SNARE PROTEINS; TYROSINE;

EID: 84881266007     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/1478-811X-11-57     Document Type: Article

References (46)

1. Moving the insulin-regulated glucose transporter GLUT4 into and out of storage. Holman GD, Sandoval IV, Trends Cell Biol 2001 11 173 179 10.1016/S0962-8924(01)01953-5 11306298 (Pubitemid 32295923)
2. Regulated transport of the glucose transporter GLUT4. Bryant NJ, Govers R, James DE, Nat Rev Mol Cell Biol 2002 3 267 277 10.1038/nrm782 11994746 (Pubitemid 34619262)
3. SNAREs and traffic. Hong W, Biochim Biophys Acta 2005 1744 493 517 16038056
4. SNAREpins: minimal machinery for membrane fusion. Weber T, Zemelman BV, McNew JA, Westermann B, Gmachl M, Parlati F, Sollner TH, Rothman JE, Cell 1998 92 759 772 10.1016/S0092-8674(00)81404-X 9529252 (Pubitemid 28155315)
5. Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins. Cheatham B, Volchuk A, Kahn CR, Wang L, Rhodes CJ, Klip A, Proc Natl Acad Sci USA 1996 93 15169 15173 10.1073/pnas.93.26.15169 8986782 (Pubitemid 27009571)
6. The Sec1 family: a novel family of proteins involved in synaptic transmission and general secretion. Halachmi N, Lev Z, J Neurochem 1996 66 889 897 8769846 (Pubitemid 26065883)
7. Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues. Tellam JT, McIntosh S, James DE, J Biol Chem 1995 270 5857 5863 10.1074/jbc.270.11.5857 7890715
8. Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin. Hata Y, Slaughter CA, Sudhof TC, Nature 1993 366 347 351 10.1038/366347a0 8247129 (Pubitemid 23349362)
9. n-Sec1: a neural-specific syntaxin-binding protein. Pevsner J, Hsu SC, Scheller RH, Proc Natl Acad Sci USA 1994 91 1445 1449 10.1073/pnas.91.4.1445 8108429 (Pubitemid 24059029)
10. Identification of SNAP receptors in rat adipose cell membrane fractions and in SNARE complexes co-immunoprecipitated with epitope-tagged N-ethylmaleimide-sensitive fusion protein. Timmers KI, Clark AE, Omatsu-Kanbe M, Whiteheart SW, Bennett MK, Holman GD, Cushman SW, Biochem J 1996 320 Pt 2 429 436 8973549 (Pubitemid 26417762)
11. Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes. Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K, Pessin JE, J Biol Chem 1998 273 33876 33883 10.1074/jbc.273.50.33876 9837979 (Pubitemid 29005781)
12. Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. Tellam JT, Macaulay SL, McIntosh S, Hewish DR, Ward CW, James DE, J Biol Chem 1997 272 6179 6186 10.1074/jbc.272.10.6179 9045631 (Pubitemid 27118086)
13. Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin4 in 3T3-L1 adipocytes. Tamori Y, Kawanishi M, Niki T, Shinoda H, Araki S, Okazawa H, Kasuga M, J Biol Chem 1998 273 19740 19746 10.1074/jbc.273.31.19740 9677404 (Pubitemid 28367033)
14. Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization. Kanda H, Tamori Y, Shinoda H, Yoshikawa M, Sakaue M, Udagawa J, Otani H, Tashiro F, Miyazaki J, Kasuga M, J Clin Invest 2005 115 291 301 15690082 (Pubitemid 40385471)
15. Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4. Aran V, Bryant NJ, Gould GW, BMC Biochem 2011 12 19 10.1186/1471-2091-12-19 21548926
16. Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis. Jewell JL, Oh E, Ramalingam L, Kalwat MA, Tagliabracci VS, Tackett L, Elmendorf JS, Thurmond DC, J Cell Biol 2011 193 185 199 10.1083/jcb.201007176 21444687
17. The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence. Frangioni JV, Beahm PH, Shifrin V, Jost CA, Neel BG, Cell 1992 68 545 560 10.1016/0092- 8674(92)90190-N 1739967
18. Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts. Woodford-Thomas TA, Rhodes JD, Dixon JE, J Cell Biol 1992 117 401 414 10.1083/jcb.117.2.401 1373143
19. Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum. Haj FG, Verveer PJ, Squire A, Neel BG, Bastiaens PI, Science 2002 295 1708 1711 10.1126/science.1067566 11872838 (Pubitemid 34202905)
20. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Elchebly M, Payette P, Michaliszyn E, Cromlish W, Collins S, Loy AL, Normandin D, Cheng A, Himms-Hagen J, Chan CC, et al. Science 1999 283 1544 1548 10.1126/science.283.5407.1544 10066179 (Pubitemid 29133367)
21. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, et al. Mol Cell Biol 2000 20 5479 5489 10.1128/MCB.20.15.5479- 5489.2000 10891488 (Pubitemid 30482885)
22. Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B. Delibegovic M, Bence KK, Mody N, Hong EG, Ko HJ, Kim JK, Kahn BB, Neel BG, Mol Cell Biol 2007 27 7727 7734 10.1128/MCB.00959-07 17724080 (Pubitemid 350033677)
23. Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice. Haj FG, Zabolotny JM, Kim YB, Kahn BB, Neel BG, J Biol Chem 2005 280 15038 15046 10.1074/jbc.M413240200 15699041 (Pubitemid 40562857)
24. Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced ER Stress. Delibegovic M, Zimmer D, Kauffman C, Rak K, Hong EG, Cho YR, Kim JK, Kahn BB, Neel BG, Bence KK, Diabetes 2008 58 590 599 10.2337/db08-0913 19074988
25. Neuronal PTP1B regulates body weight, adiposity and leptin action. Bence KK, Delibegovic M, Xue B, Gorgun CZ, Hotamisligil GS, Neel BG, Kahn BB, Nat Med 2006 12 917 924 10.1038/nm1435 16845389 (Pubitemid 44175143)
26. Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis. Owen C, Czopek A, Agouni A, Grant L, Judson R, Lees EK, McIlroy GD, Goransson O, Welch A, Bence KK, et al. PLoS One 2012 7 32700 10.1371/journal.pone.0032700 22389718
27. Adipocytes as regulators of energy balance and glucose homeostasis. Rosen ED, Spiegelman BM, Nature 2006 444 847 853 10.1038/nature05483 17167472 (Pubitemid 46024991)
28. Molecular determinants of brown adipocyte formation and function. Farmer SR, Genes Dev 2008 22 1269 1275 10.1101/gad.1681308 18483216 (Pubitemid 351717518)
29. Human brown adipose tissue. Enerback S, Cell Metab 2010 11 248 252 10.1016/j.cmet.2010.03.008 20374955
30. Protein-tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation. Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, Aboubechara D, Melhem R, Stanhope K, Cummings B, et al. J Biol Chem 2013 288 17360 17371 10.1074/jbc.M112.441469 23640882
31. Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1B. Matsuo K, Bettaieb A, Nagata N, Matsuo I, Keilhack H, Haj FG, PLoS One 2011 6 16446 10.1371/journal.pone.0016446 21305007
32. Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases. Flint AJ, Tiganis T, Barford D, Tonks NK, Proc Natl Acad Sci USA 1997 94 1680 1685 10.1073/pnas.94.5.1680 9050838 (Pubitemid 27113895)
33. The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosis. Oh E, Thurmond DC, J Biol Chem 2006 281 17624 17634 10.1074/jbc.M601581200 16638745 (Pubitemid 44035561)
34. Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytes. Umahara M, Okada S, Yamada E, Saito T, Ohshima K, Hashimoto K, Yamada M, Shimizu H, Pessin JE, Mori M, Endocrinology 2008 149 40 49 17916632
35. Protein tyrosine phosphatase substrate specificity: size and phosphotyrosine positioning requirements in peptide substrates. Zhang ZY, Maclean D, McNamara DJ, Sawyer TK, Dixon JE, Biochemistry 1994 33 2285 2290 10.1021/bi00174a040 7509638 (Pubitemid 24099629)
36. Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatase-1B. Haj FG, Markova B, Klaman LD, Bohmer FD, Neel BG, J Biol Chem 2003 278 739 744 10.1074/jbc.M210194200 12424235 (Pubitemid 36790744)
37. PTP1B regulates cortactin tyrosine phosphorylation by targeting Tyr446. Stuible M, Dube N, Tremblay ML, J Biol Chem 2008 283 15740 15746 10.1074/jbc.M710534200 18387954
38. Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2alpha signaling in brown adipocytes. Bettaieb A, Matsuo K, Matsuo I, Wang S, Melhem R, Koromilas AE, Haj FG, PLoS One 2012 7 34412 10.1371/journal.pone.0034412 22509299
39. Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B. Salmeen A, Andersen JN, Myers MP, Tonks NK, Barford D, Mol Cell 2000 6 1401 1412 10.1016/S1097-2765(00) 00137-4 11163213 (Pubitemid 32045932)
40. Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate. Huyer G, Liu S, Kelly J, Moffat J, Payette P, Kennedy B, Tsaprailis G, Gresser MJ, Ramachandran C, J Biol Chem 1997 272 843 851 10.1074/jbc.272.2.843 8995372 (Pubitemid 27034572)
41. Munc18c in adipose tissue is downregulated in obesity and is associated with insulin. Garrido-Sanchez L, Escote X, Coin-Araguez L, Fernandez-Garcia JC, El Bekay R, Vendrell J, Garcia-Fuentes E, Tinahones FJ, PLoS One 2013 8 63937 10.1371/journal.pone.0063937 23700440
42. Skeletal muscle munc18c and syntaxin 4 in human obesity. Bergman BC, Cornier MA, Horton TJ, Bessesen DH, Eckel RH, Nutr Metab (Lond) 2008 5 21 10.1186/1743-7075-5-21
43. Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. Meng TC, Buckley DA, Galic S, Tiganis T, Tonks NK, J Biol Chem 2004 279 37716 37725 10.1074/jbc.M404606200 15192089 (Pubitemid 39195485)
44. Differential regulation of endoplasmic reticulum stress by protein tyrosine phosphatase 1B and T cell protein tyrosine phosphatase. Bettaieb A, Liu S, Xi Y, Nagata N, Matsuo K, Matsuo I, Chahed S, Bakke J, Keilhack H, Tiganis T, Haj FG, J Biol Chem 2011 286 9225 9235 10.1074/jbc.M110.186148 21216966
45. Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells. Samali A, Cai J, Zhivotovsky B, Jones DP, Orrenius S, Embo J 1999 18 2040 2048 10.1093/emboj/18.8.2040 10205158 (Pubitemid 29179161)
46. GLUT4 exocytosis. Stockli J, Fazakerley DJ, James DE, J Cell Sci 2011 124 4147 4159 10.1242/jcs.097063 22247191