Engineering and refolding of a novel trimeric fusion protein TRAIL-collagen XVIII NC1

Applied Microbiology and Biotechnology

Volumn 97, Issue 16, 2013, Pages 7253-7264

  Pan, Li Qiang ^a   Xie, Zhang Ming ^a   Tang, Xiao Jing ^a   Wu, Min ^a   Wang, Fu Rong ^a   Naranmandura, Hua ^a   Chen, Shu Qing ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; Non collagenous domain; Protein refolding; TRAIL; Two step refolding approach

Indexed keywords

APOPTOSIS ACTIVITY; CONVENTIONAL METHODS; GEL-FILTRATION CHROMATOGRAPHY; NON-COLLAGENOUS DOMAIN; PROTEIN REFOLDING; REFOLDING; TRAIL; TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGANDS;

CELL CULTURE; CHROMATOGRAPHY; COLLAGEN; ESCHERICHIA COLI; GEL PERMEATION CHROMATOGRAPHY; OLIGOMERS;

CELL DEATH;

ANTINEOPLASTIC AGENT; COLLAGEN TYPE 18; HYBRID PROTEIN; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND COLLAGEN XVIII NON COLLAGENOUS DOMAIN FUSION PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND COLLAGEN XVIII TRIMERIZATION DOMAIN FUSION PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; COLLAGEN; DILUTION; LIGAND; TUMOR;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL INCLUSION; CONTROLLED STUDY; DILUTION; DRUG HALF LIFE; ESCHERICHIA COLI; GEL FILTRATION CHROMATOGRAPHY; GEL PERMEATION CHROMATOGRAPHY; GENE EXPRESSION SYSTEM; GENE FUSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN REFOLDING; PROTEIN STABILITY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CHROMATOGRAPHY, GEL; COLLAGEN TYPE XVIII; EPITHELIAL CELLS; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; PROTEIN FOLDING; RECOMBINANT FUSION PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

ESCHERICHIA COLI;

EID: 84881256983     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-012-4604-0     Document Type: Article

References (35)

1. Ahn JH, Lee YP, Rhee JS (1997) Investigation of refolding condition for Pseudomonas fluorescens lipase by response surface methodology. J Biotechnol 54(3):151-160. doi: 10.1016/S0168-1656(97)01693-3 (Pubitemid 27285998)
2. Batas B, Chaudhuri JB (1996) Protein refolding at high concentration using size-exclusion chromatography. Biotechnol Bioeng 50(1):16-23. doi:10.1002/(SICI)1097-0290(19960405)50:1<16::AID-BIT3>3.0.CO;2-4 (Pubitemid 26086779)
3. Batas B, Chaudhuri JB (1999) Considerations of sample application and elution during size-exclusion chromatography-based protein refolding. J Chromatogr A 864(2):229-236. doi: 10.1016/S0021-9673(99)01030-4
4. Batas B, Jones HR, Chaudhuri JB (1997) Studies of the hydrodynamic volume changes that occur during refolding of lysozyme using size-exclusion chromatography. J Chromatogr A 766(1-2):109-119. doi: 10.1016/S0021-9673(96) 01020-5 (Pubitemid 27166338)
5. Bodmer JL, Meier P, Tschopp J, Schneider P (2000) Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL. J Biol Chem 275(27):20632-20637. doi: 10.1074/jbc.M909721199 (Pubitemid 30457649)
6. Boudko SP, Sasaki T, Engel J, Lerch TF, Nix J, Chapman MS, Bachinger HP (2009) Crystal structure of human collagen XVIII trimerization domain: a novel collagen trimerization Fold. J Mol Biol 392(3):787-802. doi: 10.1016/j.jmb.2009.07.057
7. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254. doi: 10.1016/0003-2697(76)90527-3
8. Buchner J, Rudolph R (1991) Renaturation, purification and characterization of recombinant Fab-fragments produced in Escherichia coli. Biotechnology (N Y) 9(2):157-162. doi: 10.1038/nbt0291-157
9. Cardamone M, Puri NK, Brandon MR (1995) Comparing the refolding and reoxidation of recombinant porcine growth hormone from a urea denatured state and from Escherichia coli inclusion bodies. Biochemistry 34(17):5773-5794. doi: 10.1021/bi00017a009
10. Clark EDB (1998) Refolding of recombinant proteins. Curr Opin Biotechnol 9(2):157-163. doi: 10.1016/S0958-1669(98)80109-2 (Pubitemid 28195001)
11. Ejima D, Watanabe M, Sato Y, Date M, Yamada N, Takahara Y (1999) High yield refolding and purification process for recombinant human interleukin-6 expressed in Escherichia coli. Biotechnol Bioeng 62(3):301-310. doi:10.1002/(SICI)1097-0290(19990205)62:3<301::AID-BIT6>3.0.CO;2-W (Pubitemid 29018354)
12. Ganten TM, Koschny R, Sykora J, Schulze-Bergkamen H, Buchler P, Haas TL, Schader MB, Untergasser A, Stremmel W, Walczak H (2006) Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs. Clin Cancer Res 12(8):2640-2646. doi: 10.1158/1078-0432.CCR-05-2635
13. Gu Z, Su Z, Janson JC (2001) Urea gradient size-exclusion chromatography enhanced the yield of lysozyme refolding. J Chromatogr A 918(2):311-318. doi: 10.1016/S0021-9673(01)00766-X (Pubitemid 32432935)
14. Hamaker KH, Liu J, Seely RJ, Ladisch CM, Ladisch MR (1996) Chromatography for rapid buffer exchange and refolding of secretory leukocyte protease inhibitor. Biotechnol Prog 12(2):184-189. doi: 10.1021/bp950071f (Pubitemid 126545760)
15. He Y, Zhou H, Tang H, Luo Y (2006) Deficiency of disulfide bonds facilitating fibrillogenesis of endostatin. J Biol Chem 281(2):1048-1057. doi: 10.1074/jbc.M507745200
16. Hevehan DL, De Bernardez Clark E (1997) Oxidative renaturation of lysozyme at high concentrations. Biotechnol Bioeng 54(3):221-230. doi:10.1002/(SICI)1097-0290(19970505)54:3<221::AID-BIT3>3.0.CO;2-H (Pubitemid 27176594)
17. Ichikawa K, Liu W, Zhao L, Wang Z, Liu D, Ohtsuka T, Zhang H, Mountz JD, Koopman WJ, Kimberly RP, Zhou T (2001) Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 7(8):954-960. doi: 10.1038/91000 (Pubitemid 32756434)
18. Jo M, Kim TH, Seol DW, Esplen JE, Dorko K, Billiar TR, Strom SC (2000) Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 6(5):564-567. doi: 10.1038/75045 (Pubitemid 30305907)
19. Lawrence D, Shahrokh Z, Marsters S, Achilles K, Shih D, Mounho B, Hillan K, Totpal K, DeForge L, Schow P, Hooley J, Sherwood S, Pai R, Leung S, Khan L, Gliniak B, Bussiere J, Smith CA, Strom SS, Kelley S, Fox JA, Thomas D, Ashkenazi A (2001) Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 7(4):383-385. doi: 10.1038/86397 (Pubitemid 32298514)
20. Maeda Y, Yamada H, Ueda T, Imoto T (1996) Effect of additives on the renaturation of reduced lysozyme in the presence of 4 M urea. Protein Eng 9(5):461-465. doi: 10.1093/protein/9.5.461 (Pubitemid 26169559)
21. O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E, Birkhead JR, Olsen BR, Folkman J (1997) Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88(2):277-285. doi: 10.1016/S0092-8674(00) 81848-6 (Pubitemid 28015876)
22. Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A (1996) Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271(22):12687-12690. doi: 10.1074/jbc.271.22.12687 (Pubitemid 26175834)
23. Qin J, Chaturvedi V, Bonish B, Nickoloff BJ (2001) Avoiding premature apoptosis of normal epidermal cells. Nat Med 7(4):385-386. doi: 10.1038/86401 (Pubitemid 32298515)
24. Qin JZ, Bacon PE, Chaturvedi V, Bonish B, Nickoloff BJ (2002) Pathways involved in proliferating, senescent and immortalized keratinocyte cell death mediated by two different TRAIL preparations. Exp Dermatol 11(6):573-583. doi: 10.1034/j.1600-0625.2002.110610.x (Pubitemid 37009769)
25. Rozanov DV, Savinov AY, Golubkov VS, Rozanova OL, Postnova TI, Sergienko EA, Vasile S, Aleshin AE, Rega MF, Pellecchia M, Strongin AY (2009) Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cells. Mol Cancer Ther 8(6):1515-1525. doi: 10.1158/1535-7163.MCT-09-0202
26. Schneider P (2000) Production of recombinant TRAIL and TRAIL receptor: Fc chimeric proteins. Methods Enzymol 322:325-345. doi: 10.1016/S0076-6879(00) 22031-4 (Pubitemid 30482067)
27. Shalongo W, Ledger R, Jagannadham MV, Stellwagen E (1987) Refolding of denatured thioredoxin observed by size-exclusion chromatography. Biochemistry 26(11):3135-3141. doi: 10.1021/bi00385a029 (Pubitemid 17087849)
28. Simmons T, Newhouse YM, Arnold KS, Innerarity TL, Weisgraber KH (1997) Human low density lipoprotein receptor fragment. Successful refolding of a functionally active ligand-binding domain produced in Escherichia coli. J Biol Chem 272(41):25531-25536. doi: 10.1074/jbc.272.41.25531 (Pubitemid 27438861)
29. Stempfer G, Holl-Neugebauer B, Rudolph R (1996) Improved refolding of an immobilized fusion protein. Nat Biotechnol 14(3):329-334. doi: 10.1038/nbt0396-329 (Pubitemid 3035127)
30. Vagenende V, Yap MG, Trout BL (2009) Mechanisms of protein stabilization and prevention of protein aggregation by glycerol. Biochemistry 48(46):11084-11096. doi: 10.1021/bi900649t
31. Walczak H, Miller RE, Ariail K, Gliniak B, Griffith TS, Kubin M, Chin W, Jones J, Woodward A, Le T, Smith C, Smolak P, Goodwin RG, Rauch CT, Schuh JC, Lynch DH (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5(2):157-163. doi: 10.1038/5517 (Pubitemid 29068521)
32. Wetlaufer DB, Xie Y (1995) Control of aggregation in protein refolding: a variety of surfactants promote renaturation of carbonic anhydrase II. Protein Sci 4(8):1535-1543. doi: 10.1002/pro.5560040811
33. Wiley SR, Schooley K, Smolak PJ, Din WS, Huang C-P, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA, Goodwin RG (1995) Identification and characterization of a new member of the TNF family that induces Apoptosis. Immunity 3:673-682. doi: 10.1016/1074-7613(95)90057-8 (Pubitemid 26091143)
34. Williams DC, Van Frank RM, Muth WL, Burnett JP (1982) Cytoplasmic inclusion bodies in Escherichia coli producing biosynthetic human insulin proteins. Science 215(4533):687-689. doi: 10.1126/science.7036343 (Pubitemid 12113758)
35. Wu X, Li P, Qian C, Li O, Zhou Y (2009) Trimeric coiled-coil domain of human pulmonary surfactant protein D enhances zinc-binding ability and biologic activity of soluble TRAIL. Mol Immunol 46(11-12):2381-2388. doi: 10.1016/j.molimm.2009.03.004