Dopaminergic therapy removal differentially effects learning in schizophrenia and Parkinson's disease

Schizophrenia Research

Volumn 149, Issue 1-3, 2013, Pages 162-166

  Weickert, Thomas W ^a,b   Mattay, Venkata S ^c   Das, Saumitra ^a   Bigelow, Llewellyn B ^a   Apud, Jose A ^a   Egan, Michael F ^a   Weinberger, Daniel R ^a   Goldberg, Terry E ^d  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d ZUCKER HILLSIDE HOSPITAL   (United States)

Author keywords

Antipsychotics; Dopamimetics; Frontal striatal circuitry; Parkinson's disease; Probabilistic association learning; Schizophrenia

Indexed keywords

AMANTADINE; CARBIDOPA PLUS LEVODOPA; CLOZAPINE; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; PERGOLIDE; PRAMIPEXOLE; QUETIAPINE; RISPERIDONE; ZIPRASIDONE;

ADJUVANT THERAPY; ADULT; ARTICLE; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; FEMALE; HUMAN; LEARNING; MENTAL PERFORMANCE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROBABILISTIC ASSOCIATION LEARNING; SCHIZOPHRENIA;

ANTIPSYCHOTICS; DOPAMIMETICS; EC; ELDERLY CONTROL; FRONTAL-STRIATAL CIRCUITRY; PAL; PARKINSON'S DISEASE; PD; PROBABILISTIC ASSOCIATION LEARNING; SC; SCHIZOPHRENIA; YC; YOUNG CONTROL;

ADULT; AGED; ASSOCIATION LEARNING; DOPAMINE AGENTS; FEMALE; HUMANS; LEARNING DISORDERS; LEVODOPA; MALE; MIDDLE AGED; PARKINSON DISEASE; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84881234192     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2013.06.028     Document Type: Article

References (41)

1. Aosaki T., Graybiel A.M., Kimura M. Effect of the nigrostriatal dopamine system on acquired neural responses in the striatum of behaving monkeys. Science 1994, 265:412-415.
2. Buchsbaum M.S., Buchsbaum B.R., Hazlett E.Z., et al. Relative glucose metabolic rate higher in white matter in patients with schizophrenia. Am. J. Psychiatry 2007, 164:1072-1081.
3. Divac I., Rosvold H.E., Szwarcbart M.K. Behavioral effects of selective ablation of the caudate nucleus. J. Comp. Physiol. Psychol. 1967, 63:184-190.
4. Elliott R., Friston K.J., Dolan R.J. Dissociable neural responses in human reward systems. J. Neurosci. 2000, 20:6159-6165.
5. Fera F., Weickert T.W., Goldberg T.E., et al. Neural mechanisms underlying probabilistic category learning in normal aging. J. Neurosci. 2005, 25:11340-11348.
6. Foerde K., Poldrack R.A., Knowlton B.J., et al. Selective cortical dysfunction in schizophrenia: examination of motor and cognitive skill learning. Neuropsychology 2008, 22:100-109.
7. Fusar-Poli P., Howes O.D., Allen P., et al. Abnormal prefrontal activation directly related to presynaptic striatal dopamine dysfunction in people at clinical high risk for psychosis. Mol. Psychiatry 2011, 16:67-75.
8. Hoehn M.M., Yahr M.D. Parkinsonism: onset, progression and mortality. Neurology 1967, 17:427-442.
9. Horan W.P., Green M.F., Knowlton B.J., Wynn J.K., Mintz J., Nuechterlein K.H. Impaired implicit learning in schizophrenia. Neuropsychology 2008, 22:606-617.
10. Hornykiewicz O. Dopamine (3-hydroxytyramine) and brain function. Pharmacol. Rev. 1966, 18:925-964.
11. Jahanshahi M., Wilkinson L., Gahir H., Dharminda A., Lagnado D.A. Medication impairs probabilistic classification learning in Parkinson's disease. Neuropsychologia 2010, 48:1096-1103.
12. Kapur S., Seeman P. Does fast dissociation from the dopamine D(2) receptor explain the action of atypical antipsychotics? A new hypothesis. Am. J. Psychiatry 2001, 158:360-369.
13. Kay S.R., Fiszbein A., Opler L.A. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr. Bull. 1987, 13:261-276.
14. Keri S., Kelemen O., Szekeres G., et al. Schizophrenics know more than they can tell: probabilistic classification learning in schizophrenia. Psychol. Med. 2000, 30:149-155.
15. Keri S., Juhasz A., Rimanoczy A., et al. Habit learning and the genetics of the dopamine D3 receptor: evidence from patients with schizophrenia and healthy controls. Behav. Neurosci. 2005, 119:687-693.
16. Knowlton B.J., Squire L.R., Paulsen J.S., Swerdlow N.R., Swenson M. Dissociations within nondeclarative memory in Huntington's disease. Neuropsychology 1996, 10:538-548.
17. Knowlton B.J., Mangels J.A., Squire L.R. A neostriatal habit learning system in humans. Science 1996, 273:1399-1402.
18. Knutson B., Adams C.M., Fong G.W., Hommer D. Anticipation of increasing monetary reward selectively recruits nucleus accumbens. J. Neurosci. 2001, 21:RC159.
19. Laruelle M., Abi-Dargham A., van Dyck C.H., et al. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:9235-9240.
20. McDonald R.J., White N.M. A triple dissociation of memory systems: hippocampus, amygdala, and dorsal striatum. Behav. Neurosci. 1993, 107:3-22.
21. Moody T.D., Bookheimer S.Y., Vanek Z., Knowlton B.J. An implicit learning task activates medial temporal lobe in patients with Parkinson's disease. Behav. Neurosci. 2004, 118:438-442.
22. Morris R.W., Vercammen A., Lenroot R., et al. Disambiguating ventral striatum fMRI related BOLD signal during reward prediction in schizophrenia. Mol. Psychiatry 2012, 17:280-289.
23. Murray G.K., Corlett P.R., Clark L., et al. Substantia nigra/ventral tegmental reward prediction error disruption in psychosis. Mol. Psychiatry 2008, 13:267-276.
24. Packard M.G., Hirsh R., White N.M. Differential effects of fornix and caudate nucleus lesions on two radial maze tasks: evidence for multiple memory systems. J. Neurosci. 1989, 9:1465-1472.
25. Pickens R., Harris W.C. Self-administration of d-amphetamine by rats. Psychopharmacologia 1968, 12:158-163.
26. Pickens R., Thompson T. Cocaine-reinforced behavior in rats: effects of reinforcement magnitude and fixed-ratio size. J. Pharmacol. Exp. Ther. 1968, 161:122-129.
27. Pilowsky L.S., Costa D.C., Ell P.J., Verhoeff N.P., Murray R.M., Kerwin R.W. D2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerised tomography study. Br. J. Psychiatry 1994, 164:16-26.
28. Poldrack R.A., Prabhakaran V., Seger C.A., Gabrieli J.D. Striatal activation during acquisition of a cognitive skill. Neuropsychology 1999, 13:564-574.
29. Poldrack R.A., Clark J., Pare-Blagoev E.J., et al. Interactive memory systems in the human brain. Nature 2001, 414:546-550.
30. Sage J.R., Anagnostaras S.G., Mitchell S., et al. Analysis of probabilistic classification learning in patients with Parkinson's disease before and after pallidotomy surgery. Learn. Mem. 2003, 10:226-236.
31. Saunders R.C., Kolachana B.S., Weinberger D.R. Local pharmacological manipulation of extracellular dopamine levels in dorsolateral prefrontal cortex and caudate nucleus in the rhesus monkey: an in vivo microdialysis study. Exp. Brain Res. 1994, 98:44-52.
32. Schultz W., Dayan P., Montague P.R. A neural substrate of prediction and reward. Science 1997, 275:1593-1599.
33. Shohamy D., Myers C.E., Grossman S., Sage J., Gluck M.A., Poldrack R.A. Cortico-striatal contributions to feedback based learning: converging data from neuroimaging and neuropsychology. Brain 2004, 127:851-859.
34. Shohamy D., Myers C.E., Onlaor S., Gluck M.A. Role of the basal ganglia in category learning: how do patients with Parkinson's disease learn?. Behav. Neurosci. 2004, 118:676-686.
35. Shohamy D., Myers C.E., Hopkins R.O., Sage J., Gluck M.A. Distinct hippocampal and basal ganglia contributions to probabilistic learning and reversal. J. Cogn. Neurosci. 2009, 21:1821-1833.
36. Vonsattel J.P., Myers R.H., Stevens T.J., Ferrante R.J., Bird E.D., Richardson E.P. Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 1985, 44:559-577.
37. Weickert T.W., Terrazas A., Bigelow L.B., et al. Habit and skill learning in schizophrenia: evidence of normal striatal processing with abnormal cortical input. Learn. Mem. 2002, 9:430-442.
38. Weickert T.W., Goldberg T.E., Marenco S., Bigelow L.B., Egan M.F., Weinberger D.R. Comparison of cognitive performances during a placebo period and an atypical antipsychotic treatment period in schizophrenia: critical examination of confounds. Neuropsychopharmacology 2003, 28:1491-1500.
39. Weickert T.W., Goldberg T.E., Callicott J.H., et al. Neural correlates of probabilistic category learning in patients with schizophrenia. J. Neurosci. 2009, 29:1244-1254.
40. Weickert T.W., Goldberg T.E., Egan M.F., et al. Relative risk of probabilistic learning deficits in patients with schizophrenia and their siblings. Biol. Psychiatry 2010, 67:948-955.
41. Wise R.A., Spindler J., deWit H., Gerberg G.J. Neuroleptic-induced "anhedonia" in rats: pimozide blocks reward quality of food. Science 1978, 201:262-264.