A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis

Journal of Allergy and Clinical Immunology

Volumn 132, Issue 2, 2013, Pages 371-377

  Esparza Gordillo, Jorge ^a,b   Schaarschmidt, Heidi ^c   Liang, Liming ^d   Cookson, William ^e   Bauerfeind, Anja ^b   Lee Kirsch, Min Ae ^f   Nemat, Katja ^f   Henderson, John ^g   Paternoster, Lavinia ^g   Harper, John I ^h   Mangold, Elisabeth ⁱ   Nothen, Markus M ⁱ   Rüschendorf, Franz ^b   Kerscher, Tamara ^a,b   Marenholz, Ingo ^a,b   Matanovic, Anja ^a,b   Lau, Susanne ^a   Keil, Thomas ^a   Bauer, Carl Peter ^j   Kurek, Michael ^k   Ciechanowicz, Andrzej ^k   MacEk, Milan ^l   Franke, Andre ^c   Kabesch, Michael ^m   Hubner, Norbert ^b   Abecasis, Gonçalo ⁿ   Weidinger, Stephan ^o   Moffatt, Miriam ^e   Lee, Young Ae ^a,b   more..

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c UNIVERSITY OF KIEL   (Germany)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^f DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^g UNIVERSITY OF BRISTOL   (United Kingdom)

^h GREAT ORMOND STREET HOSPITAL   (United Kingdom)

ⁱ UNIVERSITY OF BONN   (Germany)

^j TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^k POMERANIAN MEDICAL UNIVERSITY   (Poland)

^l UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^m UNIVERSITY HOSPITAL REGENSBURG   (Germany)

ⁿ UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

^o UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

more..

Author keywords

Atopic dermatitis; candidate association study; genetic risk factor; inflammation; longitudinal study; persistent atopic dermatitis; population based cohort; prognosis; single nucleotide polymorphism; soluble IL 6 receptor

Indexed keywords

INTERLEUKIN 6 RECEPTOR;

ADOLESCENT; AMINO ACID SUBSTITUTION; ARTICLE; ATOPIC DERMATITIS; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; GENETIC VARIABILITY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; INFANT; MAJOR CLINICAL STUDY; NEWBORN; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; RECEPTOR GENE; RISK ASSESSMENT; SCHOOL CHILD; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

AD; ALSPAC; ATOPIC DERMATITIS; AVON LONGITUDINAL STUDY OF PARENTS AND CHILDREN; CANDIDATE ASSOCIATION STUDY; GENETIC RISK FACTOR; GENOME-WIDE ASSOCIATION STUDY; GWAS; IL-6 RECEPTOR; IL-6R; INFLAMMATION; LONGITUDINAL STUDY; MAS; MULTICENTER ALLERGY STUDY; ODDS RATIO; OR; PERSISTENT ATOPIC DERMATITIS; POPULATION-BASED COHORT; PROGNOSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SNP; SOLUBLE IL-6 RECEPTOR;

ADOLESCENT; ALLELES; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DERMATITIS, ATOPIC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; INTERLEUKIN-6; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, INTERLEUKIN-6; RISK FACTORS;

EID: 84881153838     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2013.01.057     Document Type: Article

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