Changes in metabolic markers in insulin-producing β-cells during hypoxia-induced cell death as studied by NMR metabolomics

Journal of Proteome Research

Volumn 12, Issue 8, 2013, Pages 3738-3745

  Tian, Lianji ^a   Kim, Hoe Suk ^a,b   Kim, Heyonjin ^a,b   Jin, Xing ^a   Jung, Hye Seung ^b   Park, Kyong Soo ^b   Cho, Kyoung Won ^b   Park, Sunghyouk ^a   Moon, Woo Kyung ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

1H nuclear magnetic resonance spectroscopy; cell death; choline species; creatine; hypoxia; metabolic markers; pancreatic cell; taurine

Indexed keywords

CASPASE 3; CHOLINE; CREATINE; GLYCEROPHOSPHORYLCHOLINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TAURINE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DEATH; CELL HYPOXIA; CELL LYSATE; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; INSULIN SYNTHESIS; INTRACELLULAR FLUID; METABOLOMICS; NONHUMAN; PANCREAS ISLET BETA CELL; PATTERN RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; WESTERN BLOTTING;

EID: 84881147837     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr400315e     Document Type: Article

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